Abstract:
BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METHODS:A microsimulation model was developed to estimate alcohol-attributable diseases and injuries in patients with alcohol dependence and to explore the clinical relevance of reducing alcohol consumption. RESULTS:For all diseases and injuries considered, the number of events (inpatient episodes) increased with the number of HDDs and TAC per year. The model predicted that a reduction of 20 HDDs per year would result in 941 fewer alcohol-attributable events per 100,000 patients, while a reduction in intake of 3,000 g/year of pure alcohol (ethanol) would result in 1,325 fewer events per 100,000 patients. CONCLUSION:The potential gains of reducing consumption in alcohol-dependent patients were considerable.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
François C,Laramée P,Rahhali N,Chalem Y,Aballéa S,Millier A,Bineau S,Toumi M,Rehm Jdoi
10.1159/000362408subject
Has Abstractpub_date
2014-01-01 00:00:00pages
269-84issue
6eissn
1022-6877issn
1421-9891pii
000362408journal_volume
20pub_type
杂志文章abstract:BACKGROUND:Alcohol use among medical specialists remains a delicate topic. However, the number of prevalence studies remains very limited in Western European countries. AIMS:To explore alcohol use and hazardous drinking among male and female medical specialists. METHODS:All medical specialists in Belgium--a typical W...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341993
更新日期:2013-01-01 00:00:00
abstract::The aim of this study was to investigate to what extent alcohol-specific parenting practices relate to adolescents' alcohol use, binge drinking, and alcohol-related problems, and whether these associations are moderated by socioeconomic status (SES), i.e. parents' education level and family income. The present data we...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000110408
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Therapeutic communities (TCs) are drug-free residential settings, focused on psychosocial rehabilitation. While TCs are considered an effective method, the bulk of the research evidence is from poorly controlled studies. The goal of this study was to evaluate TC effectiveness in terms of abstinence and to de...
journal_title:European addiction research
pub_type: 杂志文章,评审
doi:10.1159/000331007
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Two forms of institutionalized pressure to treatment can be distinguished in Switzerland: civil commitment and court referral. In court referral, the referred patient has the right to refuse treatment. OBJECTIVES:To compare court referrals for inpatient treatment to voluntary therapy. METHODS:Comparison of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000052058
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Methadone maintenance treatment (MMT) has been shown to dramatically reduce illicit opioid use and criminal activity among injection drug users (IDU). However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000130418
更新日期:2008-01-01 00:00:00
abstract:AIMS:There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness o...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000485564
更新日期:2018-01-01 00:00:00
abstract:AIMS:The aim of this paper is to illustrate how Switzerland was able to play such a pioneering role in the field of addiction treatment, in creating a drug policy that includes the medical prescription of diacetylmorphine (heroin). The paper will also describe the role of knowledge brokering processes and coalition bui...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000357234
更新日期:2014-01-01 00:00:00
abstract::In the article the growing interest of studies on treatment systems rather than specific treatment modalities is taken as a starting point for a discussion and outlook on how the research agenda of drug treatment research will develop in the near future. The relative absence of research that provides substantial guida...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018984
更新日期:1999-09-01 00:00:00
abstract::The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018951
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Besides numerous advantages and commodities offered by smartphones, there are obvious unhealthy effects. The global trend of an increase in the frequency of usage of smartphones, that is, prolonged screen time, is closely related to problematic smartphone use. The aim of our study was to measure the level of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000506738
更新日期:2021-01-01 00:00:00
abstract:AIM:Little is known about whether heroin-dependent individuals receiving methadone maintenance treatment (MMT) who were discharged involuntarily and against medical advice (DAMA) get benefits before they left. The aims of this 12-month follow-up study were to examine whether the effects of MMT on depressive symptoms, h...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000342309
更新日期:2013-01-01 00:00:00
abstract:AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000331017
更新日期:2012-01-01 00:00:00
abstract::In this paper, the effectiveness of the treatment program developed by Proyecto Hombre ('Project Mankind') in Asturias, Spain, is evaluated. In a long-term follow-up (range from 73 days to 8 years) with a sample of 249 subjects, the results obtained by subjects completing the treatment (194) were compared with pre-tre...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000049484
更新日期:2002-01-01 00:00:00
abstract::Adult attention deficit/hyperactivity disorder (ADHD) often co-occurs with substance use disorders (SUD) and is associated with early onset and more severe development of SUD and with reduced treatment effectiveness. Screening tools allow for a good recognition of possible ADHD in adults with SUD and should be used ro...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000487767
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Behavioral problems in adolescence have been shown to be associated with the presence of a positive family history of alcoholism (FH+), obstetric complications (OCs), and negative parenting practices. METHOD:This study tested the relation of these factors to aggression/delinquency and attention problems in ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000073721
更新日期:2004-01-01 00:00:00
abstract:AIMS:To investigate the gender differences in the patterns of cannabis use (CU), namely frequency, times of day, social context and methods and in their association with DSM-IV cannabis dependence. METHODS:A sample of 3,904 students from German universities was recruited via an internet survey. Logistic regressions an...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000333338
更新日期:2011-01-01 00:00:00
abstract::The combination of intoxication and criminal responsibility has been a problem field for legal theory and practice for quite some time. While it has been argued in certain contexts that intoxication reduces or denies criminal responsibility, elsewhere it has been reasoned that intoxicated offenders should be held as (...
journal_title:European addiction research
pub_type: 杂志文章,评审
doi:10.1159/000018931
更新日期:1998-09-01 00:00:00
abstract:AIM:The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics was also examined. METHODS:The role of polymorphisms in the serotonin receptor 1A (5-HT1A), sero...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000173008
更新日期:2009-01-01 00:00:00
abstract::The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000052043
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND/AIMS:We investigated the psychometric properties of a German translation of the 12-item Autonomy over Tobacco Scale (AUTOS) among 1,195 eighth-grade students. METHODS:Data for this study were collected as part of the fourth wave of data collection of the Smokefree Class Competition intervention in the Saxon...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000334410
更新日期:2012-01-01 00:00:00
abstract::In Europe, adolescent substance misuse increased during the 1990s. Ireland has among the highest rates of substance misuse among schoolchildren in Europe. We sought to describe the socio-demographic and drug misuse profile of children presenting to addiction treatment services in Dublin during the 1990s. Of the 9,874 ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000076116
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND/AIMS:Opioid substitution treatment (OST) improves outcomes in opioid dependence. However, controlled drugs used in treatment may be misused or diverted, resulting in negative treatment outcomes. This review defines a framework to assess the impact of misuse and diversion. METHODS:A systematic review of publ...
journal_title:European addiction research
pub_type: 杂志文章,评审
doi:10.1159/000438988
更新日期:2016-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000441220
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Evaluation of the Addiction Severity Index (ASI) as a screen for identifying sexual and physical assault histories. METHOD:The sensitivity and specificity of the ASI assault items were examined in 146 alcoholic patients with the assault questions of the Composite International Diagnostic Interview posttrauma...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050740
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:To investigate drug use among secondary schoolchildren aged 14-18 years in the city of Szeged in Hungary in order to observe and describe drug use, smoking and alcohol intake and to find risk factors for these behaviours. METHODS:The questionnaire was concerned with recreational drug use, smoking and drinkin...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000081415
更新日期:2005-01-01 00:00:00
abstract:AIMS:To describe and assess trends in the use of hallucinogens and other adjunct drugs over a 5-year period. DESIGN:Repeated-measures cross-sectional survey. SETTING AND PARTICIPANTS:Annual magazine-based survey targeting people who use drugs in dance contexts. MEASUREMENTS:Lifetime use prevalence (ever used); age o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000095816
更新日期:2007-01-01 00:00:00
abstract::γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000324343
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000506630
更新日期:2020-01-01 00:00:00
abstract::In the UK, few doctors prescribe diamorphine for the treatment of opiate dependence to a small number of patients. A retrospective case note review of patients receiving diamorphine in 2000 was conducted in the UK to determine how and why these patients came to receive a prescription for diamorphine. Patient eligibili...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000101550
更新日期:2007-01-01 00:00:00
abstract::We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000066131
更新日期:2002-11-01 00:00:00