Substitution with buprenorphine in methadone- and morphine sulfate-dependent patients. Preliminary results.

Abstract:

:In France, during the 1990s, there have been some rapid developments in the treatment of opioid addiction with the introduction of legal substitution agents. Originally, some patients were treated with morphine sulfate, but this was superseded by high dose buprenorphine (Subutex(R)) and methadone. This resulted in those patients originally treated with morphine being transferred to either of these two licensed products. A study investigating the effects of the transition from morphine to either buprenorphine or methadone was undertaken. Supplementary to this, a trial investigating transition between these new compounds was also conducted. The primary outcome measures for these trials were retention rate, which was assessed at 5, 9 and 12 months, and the precipitation of withdrawal symptoms. The studies showed that transferring patients between substitution agents can be accomplished without severe withdrawal symptoms, although specific management may be required for transfer from high doses of methadone to buprenorphine. High long-term retention rates were observed in the studies, with most drop-outs occurring directly after transfer. Results suggest that patients on long-term buprenorphine maintenance therapy may have good compliance in comparison with other agents.

journal_name

Eur Addict Res

authors

Bouchez J,Beauverie P,Touzeau D

doi

10.1159/000052035

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

8-12

eissn

1022-6877

issn

1421-9891

pii

ear4a008

journal_volume

4 Suppl 1

pub_type

临床试验,杂志文章
  • Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism.

    abstract::A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000019011

    authors: Soyka M,Bondy B,Benda E,Preuss U,Hegerl U,Möller H

    更新日期:2000-06-01 00:00:00

  • Influence of personality disorder features on social functioning in substance-abusing women five years after compulsive residential treatment.

    abstract:BACKGROUND:Personality disorders (PD) are related to negative outcome in substance abuse treatment, and in the general population, personality disorders are related to negative outcome in overall functioning. Little is known about the impact of PD on adjustment following substance abuse treatment. METHODS:A cohort of ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000173006

    authors: Jansson I,Hesse M,Fridell M

    更新日期:2009-01-01 00:00:00

  • Increased S100B Levels in Cannabis Use Disorder.

    abstract:BACKGROUND:It has been determined that cannabis has adverse effects on brain tissue, and that increased S100 calcium binding protein B (S100B) blood levels are markers of neuronal damage. Therefore, the aim of this study was to evaluate the S100B levels in cannabis use disorder. METHOD:Thirty-two patients with cannabi...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000442046

    authors: Bayazit H,Cicek E,Selek S,Aksoy N,Karababa IF,Kandemir H,Basmaci Kandemir S

    更新日期:2016-01-01 00:00:00

  • Effectiveness of therapeutic communities: a systematic review.

    abstract:BACKGROUND:Therapeutic communities (TCs) are drug-free residential settings, focused on psychosocial rehabilitation. While TCs are considered an effective method, the bulk of the research evidence is from poorly controlled studies. The goal of this study was to evaluate TC effectiveness in terms of abstinence and to de...

    journal_title:European addiction research

    pub_type: 杂志文章,评审

    doi:10.1159/000331007

    authors: Malivert M,Fatséas M,Denis C,Langlois E,Auriacombe M

    更新日期:2012-01-01 00:00:00

  • Dual diagnosis in an inpatient drug-abuse detoxification unit.

    abstract::In Spain, detoxification in general hospitals plays an important role in the medical care of patients. We aim to provide clinicians with information on the prevalence and correlates of psychiatric co-morbidity in drug abusers in detoxification. A sample of 115 substance-abuse inpatients (mean age 31.9 +/- 6.4 years) i...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000104881

    authors: Nocon A,Bergé D,Astals M,Martín-Santos R,Torrens M

    更新日期:2007-01-01 00:00:00

  • Effects of parents' education and occupation on adolescent smoking and the mediating role of smoking-specific parenting and parent smoking.

    abstract::The current study examined the independent effects of parents' educational attainment and occupational status on adolescent smoking and mediation of smoking-specific communication and parents' smoking behaviours on this link. Data were collected in a multi-informant, full-family design in two sampling waves separated ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000321258

    authors: Ringlever L,Otten R,de Leeuw RN,Engels RC

    更新日期:2011-01-01 00:00:00

  • Family-based and case-control study of glutamate receptor GRIK3 Ser310Ala polymorphism in alcohol dependence.

    abstract:AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000341714

    authors: Grzywacz A,Małecka I,Suchanecka A,Bieńkowski P,Samochowiec J

    更新日期:2013-01-01 00:00:00

  • 5-Year trends in use of hallucinogens and other adjunct drugs among UK dance drug users.

    abstract:AIMS:To describe and assess trends in the use of hallucinogens and other adjunct drugs over a 5-year period. DESIGN:Repeated-measures cross-sectional survey. SETTING AND PARTICIPANTS:Annual magazine-based survey targeting people who use drugs in dance contexts. MEASUREMENTS:Lifetime use prevalence (ever used); age o...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000095816

    authors: McCambridge J,Winstock A,Hunt N,Mitcheson L

    更新日期:2007-01-01 00:00:00

  • Effect of methadone treatment on incarceration rates among injection drug users.

    abstract:BACKGROUND:Methadone maintenance treatment (MMT) has been shown to dramatically reduce illicit opioid use and criminal activity among injection drug users (IDU). However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect o...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000130418

    authors: Werb D,Kerr T,Marsh D,Li K,Montaner J,Wood E

    更新日期:2008-01-01 00:00:00

  • Alcohol consumption in southern Sweden after major decreases in Danish spirits taxes and increases in Swedish travellers' quotas.

    abstract:BACKGROUND:In 2003, Denmark lowered its tax on spirits, and in 2004, Sweden increased its traveller import quotas. AIM:The aim of the study was to determine whether these two changes increased self-reported alcohol consumption in southern Sweden, which is located near Denmark. METHOD:Data were collected through telep...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000314358

    authors: Gustafsson NK

    更新日期:2010-01-01 00:00:00

  • The contextualization of drug treatment - future research perspectives and concepts.

    abstract::In the article the growing interest of studies on treatment systems rather than specific treatment modalities is taken as a starting point for a discussion and outlook on how the research agenda of drug treatment research will develop in the near future. The relative absence of research that provides substantial guida...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000018984

    authors: Bergmark A

    更新日期:1999-09-01 00:00:00

  • Effectiveness of a therapeutic community treatment in Spain: a long-term follow-up study.

    abstract::In this paper, the effectiveness of the treatment program developed by Proyecto Hombre ('Project Mankind') in Asturias, Spain, is evaluated. In a long-term follow-up (range from 73 days to 8 years) with a sample of 249 subjects, the results obtained by subjects completing the treatment (194) were compared with pre-tre...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000049484

    authors: Fernández-Hermida JR,Secades-Villa R,Fernández-Ludeña JJ,Marina-González PA

    更新日期:2002-01-01 00:00:00

  • Acceptance and therapeutic practice of controlled drinking as an outcome goal by Swiss alcohol treatment programmes.

    abstract::Sixty-one percent (138/226) of Swiss inpatient and outpatient alcohol treatment programmes responded to a postal survey designed to assess the definition and acceptance of controlled drinking (CD) as a treatment objective, the degree to which a client's severity of dependence and finality of CD as an outcome goal were...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000210041

    authors: Klingemann H,Rosenberg H

    更新日期:2009-01-01 00:00:00

  • Intoxication, the law and criminal responsibility--a sparkling cocktail at times: the case studies of Canada and Germany.

    abstract::The combination of intoxication and criminal responsibility has been a problem field for legal theory and practice for quite some time. While it has been argued in certain contexts that intoxication reduces or denies criminal responsibility, elsewhere it has been reasoned that intoxicated offenders should be held as (...

    journal_title:European addiction research

    pub_type: 杂志文章,评审

    doi:10.1159/000018931

    authors: Fischer B,Rehm J

    更新日期:1998-09-01 00:00:00

  • Replacing the last week of a motivational inpatient alcohol withdrawal programme by a day-clinic setting.

    abstract::The impact on the motivation to treatment of a qualified alcohol withdrawal programme was evaluated in a pre/post setting. Over a period of 2 years we compared the results of replacing the last week of an inpatient setting by day-clinic treatment. In the first year, 202 patients were treated in a 3-week inpatient sett...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000050717

    authors: Reymann G,Danziger HJ

    更新日期:2001-07-01 00:00:00

  • Effectiveness of text versus pictorial health warning labels and predictors of support for plain packaging of tobacco products within the European Union.

    abstract:BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000366019

    authors: Agaku IT,Filippidis FT,Vardavas CI

    更新日期:2015-01-01 00:00:00

  • Can heroin-dependent individuals benefit from a methadone maintenance treatment program before they drop out against medical advice? A 12-month follow-up study.

    abstract:AIM:Little is known about whether heroin-dependent individuals receiving methadone maintenance treatment (MMT) who were discharged involuntarily and against medical advice (DAMA) get benefits before they left. The aims of this 12-month follow-up study were to examine whether the effects of MMT on depressive symptoms, h...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000342309

    authors: Wang PW,Wu HC,Lin HC,Yen CN,Yeh YC,Chung KS,Chang HC,Yen CF

    更新日期:2013-01-01 00:00:00

  • Psychological distress in alcohol-dependent patients. Evaluating inpatient treatment with the symptom checklist (SCL-90-R).

    abstract::The aim of this study was to evaluate the change of psychological distress measured by the symptom checklist in alcohol dependent inpatients during treatment and at follow-up. In addition, psychological distress as a predictive variable for abstinence or relapse during a 1-year follow-up was investigated. In a sample ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000090424

    authors: Sander W,Jux M

    更新日期:2006-01-01 00:00:00

  • Association between early onset of cigarette, alcohol and cannabis use and later drug use patterns: an analysis of a survey in European metropolises.

    abstract:OBJECTIVES:The study presents data about age of onset of alcohol, cigarette and cannabis use and investigates the association between age of onset and later drug use patterns. METHODS:Using a sample from a cross-sectional multi-site study, personal interviews were conducted with 3,503 individuals aged 12-49 years. Las...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000083038

    authors: Baumeister SE,Tossmann P

    更新日期:2005-01-01 00:00:00

  • Fatal Overdoses of Opioids in Israel 2005-2014.

    abstract:AIMS:To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005-2014. METHODS:Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000485033

    authors: Feingold D,Goldberger N,Haklai Z,Lev-Ran S

    更新日期:2017-01-01 00:00:00

  • Outpatient alcohol detoxification: implementation efficacy and outcome effectiveness of a model project.

    abstract:BACKGROUND:The aim of the study was to examine the practicability and implementation efficacy of an alcohol outpatient detoxification model and the concomitant 'motivational' psychotherapeutic approach. METHOD:This was an open prospective study to examine the implementation efficacy, practicability and medical safety ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000079840

    authors: Soyka M,Horak M

    更新日期:2004-01-01 00:00:00

  • Anabolic androgenic steroids in the general population: user characteristics and associations with substance use.

    abstract:AIMS:To analyse correlates of anabolic androgenic steroids (AAS) use in the general male population. DESIGN:A national household survey. PARTICIPANTS:Individuals aged 15-64 years in Sweden. MEASUREMENTS:AAS use and potential correlates of AAS use, including demographic data, financial situation, physical training, a...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000333037

    authors: Hakansson A,Mickelsson K,Wallin C,Berglund M

    更新日期:2012-01-01 00:00:00

  • A World Health Organization perspective on alcohol and illicit drug use and health.

    abstract::Alcohol and illicit drug use has a significant impact on global health. Alcohol consumption is increasing worldwide, particularly in developing countries and countries in transition, leading to an increasing number of health and social problems, both acute and chronic. Illicit drug use is also increasing, particularly...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000050727

    authors: Monteiro MG

    更新日期:2001-08-01 00:00:00

  • The Depression, Anxiety and Stress Scale (DASS-21) as a Screener for Depression in Substance Use Disorder Inpatients: A Pilot Study.

    abstract::Depression is a common co-morbid disorder in substance use disorder (SUD) patients. Hence, valid instruments are needed to screen for depression in this subpopulation. In this study, the predictive validity of the Depression, Anxiety and Stress Scale (DASS-21) for the presence of a depressive disorder was investigated...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000485182

    authors: Beaufort IN,De Weert-Van Oene GH,Buwalda VAJ,de Leeuw JRJ,Goudriaan AE

    更新日期:2017-01-01 00:00:00

  • The Early Developmental Stages of Psychopathology Study (EDSP): a methodological update.

    abstract::The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000052043

    authors: Lieb R,Isensee B,von Sydow K,Wittchen HU

    更新日期:2000-12-01 00:00:00

  • Simultaneous versus delayed treatment of tobacco dependence in alcohol-dependent outpatients.

    abstract:INTRODUCTION:There is a high prevalence of smoking among heavy drinkers, which is often forgotten even though it has important health consequences. AIM:To evaluate the effects that providing an intensive tobacco cessation treatment simultaneously with alcohol dependence treatment versus delayed treatment (first alcoho...

    journal_title:European addiction research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000321256

    authors: Nieva G,Ortega LL,Mondon S,Ballbè M,Gual A

    更新日期:2011-01-01 00:00:00

  • Neuro-Immuno-Endocrine Interactions in Early Life Stress and Heroin Withdrawal Timeline.

    abstract::Both heroin abuse and early life stress (ELS) affect the immune system and the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, accelerated aging due to mild inflammation has been indicated in these conditions. The present study aims to compare plasma levels of apoptosis markers, inflammatory markers, and stre...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000503880

    authors: Moeini M,Esmaeil N,Mokhtari HR,Eskandari N,Banafshe HR

    更新日期:2020-01-01 00:00:00

  • Treatment outcome in alcoholism - a comparison of self-report and the biological markers carbohydrate-deficient transferrin and gamma-glutamyl transferase.

    abstract::The primary source for evaluating treatment outcome in alcoholism is usually verbal self-report. Because the validity of self-report is often doubted, more objective markers for treatment outcome are needed. In this study, we compared self-report data from 238 male alcohol-dependent patients participating in a combine...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000018972

    authors: Mundle G,Ackermann K,Günthner A,Munkes J,Mann K

    更新日期:1999-06-01 00:00:00

  • Primary Care of Opioid use Disorder: The End of "the French Model"?

    abstract:BACKGROUND:In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000506630

    authors: Dupouy J,Maumus-Robert S,Mansiaux Y,Pariente A,Lapeyre-Mestre M

    更新日期:2020-01-01 00:00:00

  • Drugs on prescription--the Swedish experiment of 1965-67 in retrospect.

    abstract::The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...

    journal_title:European addiction research

    pub_type: 杂志文章

    doi:10.1159/000018951

    authors: Lenke L,Olsson B

    更新日期:1998-12-01 00:00:00