Abstract:
:In France, during the 1990s, there have been some rapid developments in the treatment of opioid addiction with the introduction of legal substitution agents. Originally, some patients were treated with morphine sulfate, but this was superseded by high dose buprenorphine (Subutex(R)) and methadone. This resulted in those patients originally treated with morphine being transferred to either of these two licensed products. A study investigating the effects of the transition from morphine to either buprenorphine or methadone was undertaken. Supplementary to this, a trial investigating transition between these new compounds was also conducted. The primary outcome measures for these trials were retention rate, which was assessed at 5, 9 and 12 months, and the precipitation of withdrawal symptoms. The studies showed that transferring patients between substitution agents can be accomplished without severe withdrawal symptoms, although specific management may be required for transfer from high doses of methadone to buprenorphine. High long-term retention rates were observed in the studies, with most drop-outs occurring directly after transfer. Results suggest that patients on long-term buprenorphine maintenance therapy may have good compliance in comparison with other agents.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
Bouchez J,Beauverie P,Touzeau Ddoi
10.1159/000052035subject
Has Abstractpub_date
1998-01-01 00:00:00pages
8-12eissn
1022-6877issn
1421-9891pii
ear4a008journal_volume
4 Suppl 1pub_type
临床试验,杂志文章abstract::A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000019011
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Personality disorders (PD) are related to negative outcome in substance abuse treatment, and in the general population, personality disorders are related to negative outcome in overall functioning. Little is known about the impact of PD on adjustment following substance abuse treatment. METHODS:A cohort of ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000173006
更新日期:2009-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000442046
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Therapeutic communities (TCs) are drug-free residential settings, focused on psychosocial rehabilitation. While TCs are considered an effective method, the bulk of the research evidence is from poorly controlled studies. The goal of this study was to evaluate TC effectiveness in terms of abstinence and to de...
journal_title:European addiction research
pub_type: 杂志文章,评审
doi:10.1159/000331007
更新日期:2012-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000104881
更新日期:2007-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000321258
更新日期:2011-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341714
更新日期:2013-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000095816
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Methadone maintenance treatment (MMT) has been shown to dramatically reduce illicit opioid use and criminal activity among injection drug users (IDU). However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000130418
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:In 2003, Denmark lowered its tax on spirits, and in 2004, Sweden increased its traveller import quotas. AIM:The aim of the study was to determine whether these two changes increased self-reported alcohol consumption in southern Sweden, which is located near Denmark. METHOD:Data were collected through telep...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000314358
更新日期:2010-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018984
更新日期:1999-09-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000049484
更新日期:2002-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000210041
更新日期:2009-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章,评审
doi:10.1159/000018931
更新日期:1998-09-01 00:00:00
abstract::The impact on the motivation to treatment of a qualified alcohol withdrawal programme was evaluated in a pre/post setting. Over a period of 2 years we compared the results of replacing the last week of an inpatient setting by day-clinic treatment. In the first year, 202 patients were treated in a 3-week inpatient sett...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050717
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000366019
更新日期:2015-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000342309
更新日期:2013-01-01 00:00:00
abstract::The aim of this study was to evaluate the change of psychological distress measured by the symptom checklist in alcohol dependent inpatients during treatment and at follow-up. In addition, psychological distress as a predictive variable for abstinence or relapse during a 1-year follow-up was investigated. In a sample ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000090424
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The study presents data about age of onset of alcohol, cigarette and cannabis use and investigates the association between age of onset and later drug use patterns. METHODS:Using a sample from a cross-sectional multi-site study, personal interviews were conducted with 3,503 individuals aged 12-49 years. Las...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000083038
更新日期:2005-01-01 00:00:00
abstract:AIMS:To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005-2014. METHODS:Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485033
更新日期:2017-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000079840
更新日期:2004-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000333037
更新日期:2012-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050727
更新日期:2001-08-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485182
更新日期:2017-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000052043
更新日期:2000-12-01 00:00:00
abstract:INTRODUCTION:There is a high prevalence of smoking among heavy drinkers, which is often forgotten even though it has important health consequences. AIM:To evaluate the effects that providing an intensive tobacco cessation treatment simultaneously with alcohol dependence treatment versus delayed treatment (first alcoho...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000321256
更新日期:2011-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000503880
更新日期:2020-01-01 00:00:00
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journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018972
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000506630
更新日期:2020-01-01 00:00:00
abstract::The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018951
更新日期:1998-12-01 00:00:00