The Escherichia coli starvation gene cstC is involved in amino acid catabolism.

Abstract:

:Escherichia coli strains mutant in the starvation gene cstC grow normally in a mineral salts medium but are impaired in utilizing amino acids as nitrogen sources. They are also compromised in starvation survival, where amino acid catabolism is important. The cstC gene encodes a 406-amino-acid protein that closely resembles the E. coli ArgD protein, which is involved in arginine biosynthesis. We postulate that CstC is a counterpart of ArgD in an amino acid catabolic pathway. The cstC upstream region contains several regulatory consensus sequences. Both sigmaS and sigma54 promoters are probably involved in cstC transcription and appear to compete with each other, presumably to match cstC expression to the cellular amino acid catabolic needs.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Fraley CD,Kim JH,McCann MP,Matin A

doi

10.1128/JB.180.16.4287-4290.1998

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

4287-90

issue

16

eissn

0021-9193

issn

1098-5530

journal_volume

180

pub_type

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