In vivo interaction of endotoxin with a plasma lipoprotein having esterase activity.

Abstract:

:Circulating endotoxin was specifically precipitated from plasma samples withdrawn from three different animal species subsequent to parenteral injection of the toxin. Lipoprotein-positive staining and esterase activity were demonstrated on the precipitation lines formed in immunodiffusion, thus establishing the in vivo interaction of endotoxin with a plasma lipoprotein having esterase activity. Evidence was given to show that the intensity of this interaction in circulating plasma increased gradually with time. The concordance of this in vivo inter-action with the in vitro degradation and inactivation of endotoxin by plasma esterases is discussed.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Skarnes RC

doi

10.1128/JB.95.6.2031-2034.1968

subject

Has Abstract

pub_date

1968-06-01 00:00:00

pages

2031-4

issue

6

eissn

0021-9193

issn

1098-5530

journal_volume

95

pub_type

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