Abstract:
BACKGROUND:Mortality from smoking-related diseases in women is increasing worldwide. Studies comparing hazards associated with smoking in women and men based on a sufficient number of heavy smokers of both genders are lacking. METHODS:We used pooled data from three prospective population studies conducted in Copenhagen to compare total and cause-specific mortality in relation to smoking habits. A total of 30917 subjects, 44% women, with initial examinations between 1964 and 1992 were followed until 1994 for date and cause of death. RESULTS:During follow up, 2900 women and 5744 men died. Smoking characteristics differed considerably with gender, particularly in the older subjects. Overall mortality rates in smokers were approximately twice those in people who never smoked. Positive associations with smoking in both men and women were confirmed for all-cause mortality as well as mortality from respiratory disease, vascular disease, lung cancer, and other tobacco-related cancers. Despite large gender differences in age at smoking debut, total and cause-specific relative mortality in smokers was similar in men and women. After excluding non-inhalers, relative risks associated with smoking for respiratory and vascular disease were higher for women than men whereas there were no gender differences in smoking related risk of cancers. CONCLUSIONS:The relative risks suggest that women may be more sensitive than men to some of the deleterious effects of smoking. However, because of lower baseline mortality rates in women, rate differences may be similar and results should be interpreted with caution.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Prescott E,Osler M,Andersen PK,Hein HO,Borch-Johnsen K,Lange P,Schnohr P,Vestbo Jdoi
10.1093/ije/27.1.27subject
Has Abstractpub_date
1998-02-01 00:00:00pages
27-32issue
1eissn
0300-5771issn
1464-3685journal_volume
27pub_type
杂志文章abstract::Using data from seven malformation monitoring systems around the world, the feasibility of monitoring fresh dominant mutations using skeletal dysplasias was explored. Based on a total of over 9.5 million births, 1500 infants with skeletal dysplasias were identified (16 per 100,000). In spite of efforts to get exact di...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.1.107
更新日期:1993-02-01 00:00:00
abstract::Aetiology confronts two distinct issues: the determinants of individual cases, and the determinants of incidence rate. If exposure to a necessary agent is homogeneous within a population, then case/control and cohort methods will fail to detect it: they will only identify markers of susceptibility. The corresponding s...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.1.32
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:Extended breastfeeding is known to benefit the health of children in developing countries and despite widespread expectations of a decline in breastfeeding in these countries, it has been demonstrated that the incidence and duration of breastfeeding are in fact increasing many countries. METHODS:In this pap...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.1.94
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:Urbanization in developing countries is usually accompanied by migration to cities, making it a challenge to unpack the independent relationships between migration, urbanization and health, particularly in the presence of health-selective migration. Since 1978, unprecedented planned urbanization has taken pl...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz031
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Sub-Saharan Africa (SSA) has the highest burden of HIV in the world and a rising prevalence of cardiometabolic disease; however, the interrelationship between HIV, antiretroviral therapy (ART) and cardiometabolic traits is not well described in SSA populations. METHODS:We conducted a systematic review and m...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyt198
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism. METHODS:We used multivariable linear regression and a negative control design to examine offspring epigenome-wide DNA me...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyv042
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to analyse misclassification of height, weight and body mass index (BMI), derived from mail questionnaires, and its dependency on socioeconomic factors. METHODS:A random sample of 4442 adults aged 18-84 years, living in Stockholm county, Sweden, were in 1984-1985 asked about th...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.4.860
更新日期:1997-08-01 00:00:00
abstract::METHODS. Mortality rates for four types of cancer (stomach, colorectal, lung, and breast cancer) in migrant populations were compared to those of individuals who still resided in the political region in which they were born. The effects on mortality rates of place of birth and of place of residence were studied, compa...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.1.8
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:It is unclear when in the life course do social inequalities in inflammation emerge. We examined whether the association between socioeconomic position (SEP) and C-reactive protein (CRP) is determined at conception, in childhood, adolescence or adulthood in 1484 participants from the population-based Cardiov...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym244
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The protective effect of a vaccine following an outbreak is often measured by the vaccine efficacy statistic, namely one minus the ratio of attack rates in vaccinees and non-vaccinees. This quantity is not an adequate measure of the population-level benefits of the vaccine. METHODS:We discuss two measures o...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.6.1249
更新日期:1995-12-01 00:00:00
abstract::This cohort profile describes the origins, tracing, recruitment, testing and follow-up of the University of Edinburgh-based Lothian Birth Cohorts of 1921 (LBC1921; N = 550) and 1936 (LBC1936; N = 1091). The participants undertook a general intelligence test at age 11 years and were recruited for these cohorts at mean ...
journal_title:International journal of epidemiology
pub_type: 历史文章,杂志文章
doi:10.1093/ije/dyr197
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:The long average incubation time from HIV infection to AIDS makes it difficult to estimate recent HIV transmission from AIDS incidence data. Age-period-cohort (APC) analysis can separate out the effects of age, calendar time and birth cohort to provide a clearer picture of transmission trends. METHODS:AIDS ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.6.1141
更新日期:1999-12-01 00:00:00
abstract::In an extensive health survey 115 male viscose rayon workers exposed to carbon disulphide (CS2) and 76 referents not exposed to this chemical were interviewed using the WHO cardiovascular questionnaire and responded to a self-administered questionnaire. A 12-lead ECG was taken and coded using the Minnesota code. Blood...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.4.745
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Associations between soy, dairy intakes and breast cancer risk are inconsistent. No studies exist with large numbers of dairy consumers and soy consumers to assess mutual confounding. METHODS:The study cohort contains 52 795 North American women, initially free of cancer, followed for 7.9 years (29.7% were ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa007
更新日期:2020-10-01 00:00:00
abstract::A matched case-control study among cervical cancer patients in Denmark was conducted to evaluate the possible influence of radiation therapy on leukaemia risk. Among 25718 women treated between 1943-1977, 27 cases of leukaemia occurred one or more years after diagnosis. Four controls were matched to each case on age, ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.3.363
更新日期:1985-09-01 00:00:00
abstract::Examinations of 'healthy' men in Helsinki and in rural west and east Finland in 1956 included estimation of total cholesterol and that in the HDL and beta fractions separated by electrophoresis. Vital status to the end of 1980 has been ascertained for all but eight of the 526 men aged 35-61 and for all but two of 261 ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/13.4.428
更新日期:1984-12-01 00:00:00
abstract:OBJECTIVES:The aim of the present historical cohort study was to enhance the understanding of the unusual mortality pattern seen among seafarers. The main object was to describe the mortality pattern of Danish seafarers in recent years with special reference to the influence of accidents in the maritime workplace and a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.6.1237
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND:Genetic and maternal prenatal environmental factors as well as the post-natal rearing environment may contribute to the association between childhood socioeconomic circumstances and later mortality. In order to disentangle these influences, we studied all-cause and cause-specific mortality in a cohort of ado...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyl045
更新日期:2006-10-01 00:00:00
abstract::This paper describes a means of analysing the effects that the benefit of early treatment, lead time and length-biased sampling (and other forms of prognostic selection bias) have on the mortality rate of cases detected in screening programmes. Both benefit and lead time reduce the mortality rate of screen-detected ca...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/11.3.261
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that the serum level of sialic acid is associated positively with mortality from coronary disease and stroke. In this study its relation with carotid atherosclerosis was evaluated. METHODS:From the Atherosclerosis Risk in Communities (ARIC) Study, 323 cases with carotid intima-me...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/25.5.953
更新日期:1996-10-01 00:00:00
abstract::This population-based study examines whether dietary intake in middle-aged Italian women is influenced by alcohol drinking habits. The 499 participants were interviewed using a dietary history questionnaire designed to investigate alcohol consumption. Mean intake of total and non-alcohol energy increased progressively...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.3.663
更新日期:1991-09-01 00:00:00
abstract::One task faced by public health surveillance practitioners is the timely identification of data patterns that might suggest the onset of an epidemic period. Many available techniques for analysis of surveillance data are based on sequential procedures, which predict expected numbers of cases and compare this estimate ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.2.408
更新日期:1994-04-01 00:00:00
abstract::In a questionnaire administered to a general population sample of 1673 adults, a 14-item scale of social desirability was divided into two groups of questions, almost evenly divided between desirable and undesirable behaviour, the percentage answering 'true' was higher when the question was asked early than when it wa...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/5.2.125
更新日期:1976-06-01 00:00:00
abstract::The effects of smoking habits, socio-occupational factors and respiratory symptoms in the development of airflow obstruction have been studied in a working population of 575 men aged 30-54 in 1960 and surveyed in 1960 and 1972. On average, FEV1 decreased by 47 ml/annum. Apart from FEV1 level, which reflects loss since...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/8.3.201
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVES:To examine whether educational attainment and intelligence have causal effects on risk of Alzheimer's disease (AD), independently of each other. DESIGN:Two-sample univariable and multivariable Mendelian randomization (MR) to estimate the causal effects of education on intelligence and vice versa, and the to...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz280
更新日期:2020-08-01 00:00:00
abstract::Cardiovascular disease risk factor and mortality data collected since the 1978 Conference on the Decline in Coronary Heart Disease Mortality were reviewed. Risk factor and disease trends were generally parallel and compatible with current hypotheses of cause and prevention. A few discrepancies between risk factors and...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies. METHO...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyq207
更新日期:2011-04-01 00:00:00
abstract::The Themba Lethu Clinical Cohort was established in 2004 to allow large patient-level analyses from a single HIV treatment site to evaluate National Treatment Guidelines, answer questions of national and international policy relevance and to combine an economic and epidemiologic focus on HIV research. The current obje...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dys029
更新日期:2013-04-01 00:00:00
abstract::A comparative study of the effects of combined oral contraceptives (OC) on coagulation and fibrinolytic variables using standardized laboratory technique and methodology has been performed in Dublin (Ireland), Salvador (Brazil), Santiago (Chile) and Singapore. Of 777 entrants to the study, 622 were randomly allocated ...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1093/ije/20.4.913
更新日期:1991-12-01 00:00:00
abstract::The immune adherence haemagglutination assay (IAHA), widely used for human viral disease diagnosis, has been adapted for detection of rabies virus antibodies in dog sera. Rabies virus antibody titres obtained by the IAHA correlated well with those obtained by the currently accepted test for rabies antibody determinati...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.3.472
更新日期:1987-09-01 00:00:00