Abstract:
:The Themba Lethu Clinical Cohort was established in 2004 to allow large patient-level analyses from a single HIV treatment site to evaluate National Treatment Guidelines, answer questions of national and international policy relevance and to combine an economic and epidemiologic focus on HIV research. The current objectives of the Themba Lethu Clinical Cohort analyses are to: (i) provide cohort-level information on the outcomes of HIV treatment; (ii) evaluate aspects of HIV care and treatment that have policy relevance; (iii) evaluate the cost and cost-effectiveness of different approaches to HIV care and treatment; and (iv) provide a platform for studies on improving HIV care and treatment. Since 2004, Themba Lethu Clinic has enrolled approximately 30,000 HIV-positive patients into its HIV care and treatment programme, over 21,000 of whom have received anti-retroviral therapy since being enrolled. Patients on treatment are typically seen at least every 3 months with laboratory monitoring every 6 months to 1 year. The data collected include demographics, clinical visit data, laboratory data, medication history and clinical diagnoses. Requests for collaborations on analyses can be submitted to our data centre.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Fox MP,Maskew M,MacPhail AP,Long L,Brennan AT,Westreich D,MacLeod WB,Majuba P,Sanne IMdoi
10.1093/ije/dys029subject
Has Abstractpub_date
2013-04-01 00:00:00pages
430-9issue
2eissn
0300-5771issn
1464-3685pii
dys029journal_volume
42pub_type
杂志文章abstract::Operational research (OR) analysis provides information and systems to support decision making. In health care there are examples of OR being used to support decisions surrounding both the organization of health services and the treatment of individual patients. However, its uptake is currently low in spite of the inc...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.supplement_1.s90
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:This study is an attempt to apply Markov process modelling to health status switching behaviour of infants. The data for the study consist of monthly records of diagnosed illnesses for 1152 children, each observed from the month of first contact with Kasangati Health Centre, Kampala, Uganda, until age 18 mon...
journal_title:International journal of epidemiology
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更新日期:2008-04-01 00:00:00
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更新日期:2017-04-01 00:00:00
abstract::This discussion of sexually transmitted diseases (STDs) in less developed countries covers incidence/prevalence, antimicrobial resistance, sequelae, future trends, and new opportunities for STD control -- technological changes, health service changes, and social and political changes. For most countries, current, pop...
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pub_type: 杂志文章,评审
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更新日期:1985-12-01 00:00:00
abstract::The European Prospective Investigation of Cancer (EPIC) is a 10-country collaborative study in which EPIC-Norfolk is one of the UK centres. EPIC-Norfolk examined 25 639 men and women resident in East Anglia (aged 40-79 years), between 1993 and 1997. The EPIC collaboration was set up to examine the dietary determinants...
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更新日期:2014-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/26.3.635
更新日期:1997-06-01 00:00:00
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doi:10.1093/ije/29.4.715
更新日期:2000-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1989-06-01 00:00:00
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abstract:BACKGROUND:Present understanding of increased risk of Epstein-Barr virus (EBV)-related infectious mononucleosis among children of low birth order or small sibships is mainly based on old and indirect evidence. Societal changes and methodological limitations of previous studies call for new data. METHODS:We used data f...
journal_title:International journal of epidemiology
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1988-03-01 00:00:00
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更新日期:2006-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.1.56
更新日期:1988-03-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.251
更新日期:1991-03-01 00:00:00
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更新日期:2018-10-01 00:00:00
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更新日期:1996-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1995-08-01 00:00:00
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更新日期:2019-08-01 00:00:00