Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa.

Abstract:

:The Themba Lethu Clinical Cohort was established in 2004 to allow large patient-level analyses from a single HIV treatment site to evaluate National Treatment Guidelines, answer questions of national and international policy relevance and to combine an economic and epidemiologic focus on HIV research. The current objectives of the Themba Lethu Clinical Cohort analyses are to: (i) provide cohort-level information on the outcomes of HIV treatment; (ii) evaluate aspects of HIV care and treatment that have policy relevance; (iii) evaluate the cost and cost-effectiveness of different approaches to HIV care and treatment; and (iv) provide a platform for studies on improving HIV care and treatment. Since 2004, Themba Lethu Clinic has enrolled approximately 30,000 HIV-positive patients into its HIV care and treatment programme, over 21,000 of whom have received anti-retroviral therapy since being enrolled. Patients on treatment are typically seen at least every 3 months with laboratory monitoring every 6 months to 1 year. The data collected include demographics, clinical visit data, laboratory data, medication history and clinical diagnoses. Requests for collaborations on analyses can be submitted to our data centre.

journal_name

Int J Epidemiol

authors

Fox MP,Maskew M,MacPhail AP,Long L,Brennan AT,Westreich D,MacLeod WB,Majuba P,Sanne IM

doi

10.1093/ije/dys029

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

430-9

issue

2

eissn

0300-5771

issn

1464-3685

pii

dys029

journal_volume

42

pub_type

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