Abstract:
:Peptic ulcer (PU) disease is the cause of substantial morbidity and mortality in a number of countries including Australia. Despite diagnostic and treatment advances, sustained mortality from PU disease has been reported. To understand this problem a birth cohort analysis using the Median Polish Technique (MPT) was performed on 36 years of mortality data from New South Wales, Australia. The MPT allows cohort effects to be quantified, yet has rarely been applied to mortality data. Birth cohort effects detected using graphical presentation of mortality data for duodenal (DU) and gastric ulcer (GU) mortality data for both males and females, were supported by the results obtained using the MPT. The DU mortality rates for females increased significantly over the 36-year period. This increase can be explained by the presence of a birth cohort effect, with women born between 1898 and 1913 having a greater risk of dying from DU than preceding or subsequent generations. Cohort effects in GU and DU mortality data for males and in GU mortality for females were also present, although these were masked by the overall decline in PU mortality rates. The results support the findings of other studies of birth cohort effects in PU mortality data from England, Europe and Japan, and provide support for the existence of environmental factors which resulted in increased PU mortality among specific birth cohorts. Demonstration of these birth cohort effects should influence the theories of PU disease aetiology and prevention and should be considered in developing approaches for further research.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Westbrook JI,Rushworth RLdoi
10.1093/ije/22.6.1085subject
Has Abstractpub_date
1993-12-01 00:00:00pages
1085-92issue
6eissn
0300-5771issn
1464-3685journal_volume
22pub_type
杂志文章abstract:BACKGROUND:In Switzerland, assisted suicide is legal but there is concern that vulnerable or disadvantaged groups are more likely to die in this way than other people. We examined socio-economic factors associated with assisted suicide. METHODS:We linked the suicides assisted by right-to-die associations during 2003-0...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyu010
更新日期:2014-04-01 00:00:00
abstract::This paper illustrates the basis of, expectations for and evaluation of prevention from an epidemiological perspective. Specifically, the extent to which epidemiologists could and should be involved in designing and evaluating public health interventions is addressed. Changes in the view on disease causation and epide...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/24.4.655
更新日期:1995-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/5.2.125
更新日期:1976-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/dyz159
更新日期:2020-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:1996-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/dyg001
更新日期:2003-02-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1983-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/28.2.335
更新日期:1999-04-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy252
更新日期:2019-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.1.175
更新日期:2000-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/17.1.14
更新日期:1988-03-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/13.2.229
更新日期:1984-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.2.315
更新日期:1993-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/ije/dyg100
更新日期:2003-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.2.368
更新日期:1989-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyv197
更新日期:2015-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.4.926
更新日期:1989-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.4.624
更新日期:1985-12-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:10.1093/ije/dyr055
更新日期:2011-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.5.1082
更新日期:1994-10-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy212
更新日期:2018-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.1.32
更新日期:1985-03-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.6.1111
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Breast cancer is the most frequent cancer in women and the incidence has increased over time. Our objectives were to study: (1) the socioeconomic differences in breast cancer incidence and mortality in Denmark, (2) how different socioeconomic groups have contributed to the increasing incidence, (3) whether t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyg049
更新日期:2003-04-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa287
更新日期:2021-01-18 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/18.4.842
更新日期:1989-12-01 00:00:00
abstract::Workers in the corn wet-milling industry are exposed to grain dusts, pesticides and fumigants, acids, solvents, sulphur dioxide, and other chemicals used in the manufacture of starch, oil, syrup, and dextrins. In a preliminary investigation of the long-term health effects of occupational exposures in this industry, de...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.3.432
更新日期:1985-09-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/9.2.111
更新日期:1980-06-01 00:00:00