Abstract:
BACKGROUND:Melioidosis, or infection with Pseudomonas pseudomallei is an important cause of morbidity and mortality in South East Asia and Northern Australia. The epidemiology of melioidosis in Ubon Ratchatani, Northeast Thailand was studied over a 5-year period from 1987 to 1991. METHODS:Rates and, when possible, the risks of developing melioidosis were calculated. The numerator was the number of culture-proven cases of melioidosis seen in the 1000-bed referral hospital of the province. The denominators were obtained from the population census, a survey of Health, Welfare and Use of Traditional Medicine, and the North Eastern Meterological Centre, Thailand. RESULTS:The average incidence of human melioidosis was 4.4 (95% confidence interval [CI]: 3.8-5.0) per 100,000. The disease affected all ages with the highest incidence in 40-60 years olds. Melioidosis was 1.4 (95% CI: 0.4-5.3) times more common in males than females. The disease showed a significant seasonal variation in incidence, and a strong linear correlation with rainfall (r = 0.7, 95% CI: 0.5-0.9) Adults exposed to soil and water in their work (most were rice farmers) had an increased risk of melioidosis (in the 40-59 year age group, relative risk = 4.1, 95% CI: 2.4-6.9). Most adult patients had an underlying disease (mainly diabetes mellitus) predisposing them to this infection. CONCLUSION:Melioidosis may result from either acute exposure to the organism in the soil and water, or 're-activation' of an asymptomatic childhood infection (by an unidentified possibly infective seasonal cofactor). The results from this analysis are consistent with both hypotheses. Further epidemiological studies are needed to identify risk factors so that optimal strategies for control of melioidosis may be developed.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Suputtamongkol Y,Hall AJ,Dance DA,Chaowagul W,Rajchanuvong A,Smith MD,White NJdoi
10.1093/ije/23.5.1082subject
Has Abstractpub_date
1994-10-01 00:00:00pages
1082-90issue
5eissn
0300-5771issn
1464-3685journal_volume
23pub_type
杂志文章abstract::A person to person outbreak of hepatitis A is described: 90 cases of hepatitis A occurred in a small town in Calabria, southern Italy; all cases were under 18 years of age with the highest age-specific incidence rate in the 6-10 year age group. Transmission was identified by tracing close contacts with other incubatin...
journal_title:International journal of epidemiology
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更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:Prospective studies of alcohol and mortality in middle-aged men almost universally find a U-shaped relationship between alcohol consumption and risk of mortality. This review demonstrates the extent to which different studies lead to different risk estimates, analyses the putative influence of abstention as ...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/24.1.100
更新日期:1995-02-01 00:00:00
abstract::This paper illustrates the basis of, expectations for and evaluation of prevention from an epidemiological perspective. Specifically, the extent to which epidemiologists could and should be involved in designing and evaluating public health interventions is addressed. Changes in the view on disease causation and epide...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/24.4.655
更新日期:1995-08-01 00:00:00
abstract::Mortality rates for cancers of 13 sites in 34 countries were analysed using two data reduction techniques, factor and cluster analysis. Factor analysis identified two independent underlying factors which appear to influence cancer mortality patterns. The first factor, which appears to be related to affluence, may repr...
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更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:There is considerable interest in estimating the causal effect of a range of maternal environmental exposures on offspring health-related outcomes. Previous attempts to do this using Mendelian randomization methodologies have been hampered by the paucity of epidemiological cohorts with large numbers of genot...
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abstract:BACKGROUND:Burgeoning global mental health endeavors have renewed debates about cultural applicability of psychiatric categories. This study's goal is to review strengths and limitations of literature comparing psychiatric categories with cultural concepts of distress (CCD) such as cultural syndromes, culture-bound syn...
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pub_type: 杂志文章,meta分析,评审
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更新日期:2014-04-01 00:00:00
abstract::In the Hérault region of France, vineyards cover an area of 128,000 hectares (60% of agricultural land) and involve more than 93% of farms. A vine-growing exposure matrix was built for assessing pesticide exposure. It is based on information obtained from a survey among 85 vine-growers who lived in Hérault and who had...
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abstract:BACKGROUND:This prospective study was performed in order to investigate the effect of baseline body mass index (BMI), BMI changes, baseline alcohol consumption, and changes in alcohol consumption on liver enzyme activity. METHODS:This study population consisted of 6846 male workers in a steel manufacturing company who...
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更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:We enrolled a cohort of primary schoolchildren with a history of wheeze (n = 148) in an 11-month longitudinal study to examine the relationship between ambient ozone concentrations and peak expiratory flow rate. METHODS:Enrolled children recorded peak expiratory flow rates (PEFR) twice daily. We obtained ai...
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doi:
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abstract:BACKGROUND:The reproducibility and validity of self-administered questionnaires on physical activity and inactivity were examined in a random (representative) sample of the Nurses' Health Study II cohort and a random sample of African-American women in that cohort. METHODS:Repeat questionnaires were administered 2 yea...
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pub_type: 临床试验,杂志文章
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更新日期:1994-10-01 00:00:00
abstract::Several conditions, whose timely and appropriate therapy should decrease case fatality, have been proposed as indicators of medical care quality for the National Health Service. Mortality rates for these diseases vary widely within the UK. To evaluate the contribution of varying incidence rates to these mortality diff...
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更新日期:1986-09-01 00:00:00
abstract:BACKGROUND:Cross-national comparisons of injury mortality can suggest possible causal explanations for injuries across different countries and cultures. This study identifies differences in injury mortality between Los Angeles (LA) County, California and Mexico City DF, Mexico. METHODS:Using LA County and Mexico City ...
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更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:In studies of health behaviour exploring factors associated with differences and changes in eating patterns of populations, diet is often measured with short food frequency questionnaires (FFQ). This study examines the validity of a short FFQ by comparing frequencies of food intake from the FFQ to informatio...
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pub_type: 杂志文章
doi:10.1093/ije/25.5.1023
更新日期:1996-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:A growing body of evidence supports the role of type 2 diabetes as an individual-level risk factor for tuberculosis (TB), though evidence from developing countries with the highest TB burdens is lacking. In developing countries, TB is most common among the poor, in whom diabetes may be less common. We assess...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyq238
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The increased odds of stomach cancer among subjects with blood type A have been reported in epidemiological studies. AIM:To study the relation of family history of gastric cancer and ABO blood type with precancerous gastric lesions in a high-risk area for stomach cancer. Subjects and setting We examined 340...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:The genetic basis of several familial cancers including breast and colon cancers has been identified recently. The occurrence of multiple cancers in one individual is also suggestive of a genetic predisposition. To evaluate inherited predisposition in pancreatic cancer we compared the clinical data of pancre...
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pub_type: 杂志文章
doi:10.1093/ije/29.6.999
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Aboriginal Australians experience a higher risk of diabetes than the general Australian population. In this paper, we conducted a nested case-control study to determine whether the presence of microalbuminuria and macroalbuminuria is associated with the development of diabetes among diabetes-free Aboriginal ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyl115
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Extended breastfeeding is known to benefit the health of children in developing countries and despite widespread expectations of a decline in breastfeeding in these countries, it has been demonstrated that the incidence and duration of breastfeeding are in fact increasing many countries. METHODS:In this pap...
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pub_type: 杂志文章
doi:10.1093/ije/25.1.94
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:Cost effective use of new vaccines against pneumococcal disease in children requires detailed information about the local epidemiology of pneumococcal infections. METHODS:Data on 393 culture-confirmed cases of invasive pneumococcal infection in children (<17 years) hospitalized in Swiss paediatric clinics w...
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pub_type: 临床试验,杂志文章,多中心研究
doi:10.1093/ije/27.6.1101
更新日期:1998-12-01 00:00:00
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更新日期:2003-10-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-02-01 00:00:00
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更新日期:2010-08-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2017-04-01 00:00:00
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更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:An ideological climate has persisted in Korea that has discouraged public discussion of social inequalities. Thus studies on inequalities in mortality remain undeveloped. This study is to examine age- and cause-specific socioeconomic mortality differentials for both men and women representative of the Korean...
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pub_type: 杂志文章
doi:10.1093/ije/dyg244
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism. METHODS:We used multivariable linear regression and a negative control design to examine offspring epigenome-wide DNA me...
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更新日期:2015-08-01 00:00:00
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更新日期:2019-04-01 00:00:00
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更新日期:1999-06-01 00:00:00
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更新日期:1996-02-01 00:00:00