Abstract:
:Mortality rates for cancers of 13 sites in 34 countries were analysed using two data reduction techniques, factor and cluster analysis. Factor analysis identified two independent underlying factors which appear to influence cancer mortality patterns. The first factor, which appears to be related to affluence, may represent the combined effects of high fat diets and cigarette smoking common in developed countries. The second factor may reflect the common consumption of beverages of a high tannin content such as tea, red wine and 'mate' as well as the smoking or chewing of black tobacco. Two factor scores were computed for each country, and the countries were then ranked according to their scores on each factor. Cluster analysis aggregated countries into seven distinct groups using these factor scores as the clustering criteria. Each of the groups thus defined displays a distinctive profile of site-specific cancer mortality rates. This methodology shows promise as a means of summarizing large sets of data on morbidity and mortality from a variety of cancers (and possibly other chronic diseases as well) in diverse populations.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Groves FD,Zavala DE,Correa Pdoi
10.1093/ije/16.4.501subject
Has Abstractpub_date
1987-12-01 00:00:00pages
501-8issue
4eissn
0300-5771issn
1464-3685journal_volume
16pub_type
杂志文章abstract:BACKGROUND:Despite reporting lower levels of alcohol consumption, people with lower socio-economic status (SES) experience greater alcohol-related harm. Whether differential biases in the measurement of alcohol use could explain this apparent paradox is unknown. Using alcohol biomarkers to account for measurement error...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa113
更新日期:2021-01-23 00:00:00
abstract::The clustering of xerophthalmia in villages and in households was assessed among preschool children surveyed in the Lower Shire Valley, Malawi, and in Aceh province, Indonesia. Trachoma clustering was similarly assessed among the same children in Malawi. Trachoma clustered much more than xerophthalmia among villages a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.4.865
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:Type 2 diabetes (T2D) results from a complex interplay between genetics and the environment. Several epigenome-wide association studies (EWAS) have found DNA methylation loci associated with T2D in European populations. However, data from African populations are lacking. We undertook the first EWAS for T2D a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy171
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Associations between soy, dairy intakes and breast cancer risk are inconsistent. No studies exist with large numbers of dairy consumers and soy consumers to assess mutual confounding. METHODS:The study cohort contains 52 795 North American women, initially free of cancer, followed for 7.9 years (29.7% were ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyaa007
更新日期:2020-10-01 00:00:00
abstract::Selection bias remains a more difficult bias to understand than confounding or measurement error. Past definitions have not always been illuminating and a simple method (such as the change-in-estimate method for confounding) has not been available to determine its presence and magnitude in the study sample. A better u...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy138
更新日期:2018-10-01 00:00:00
abstract::This paper describes a means of analysing the effects that the benefit of early treatment, lead time and length-biased sampling (and other forms of prognostic selection bias) have on the mortality rate of cases detected in screening programmes. Both benefit and lead time reduce the mortality rate of screen-detected ca...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/11.3.261
更新日期:1982-09-01 00:00:00
abstract::This paper examines methods for estimating the efficiency of measles and pertussis notification with particular reference to England and Wales. Crude estimates are obtained from a comparison of annual numbers of births and notifications, and this approach is modified to include detailed age-specific data. Other source...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.1.153
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:The tuberculin skin test (TST) is the most commonly used tool to detect infection with Mycobacterium tuberculosis. We sought to determine whether tuberculin skin testing is useful to detect latent infection by M. tuberculosis in a population that was vaccinated with the Bacille Calmette Guérin (BCG) vaccine....
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyl213
更新日期:2006-12-01 00:00:00
abstract::The total duration of 'ovulatory activity' or 'ovulatory age' has been reported to be the strongest indicator of the risk of ovarian cancer. In the case-control study examined in this paper this variable was found to be a strong correlate of the risk of ovarian cancer. However, the finding that in older women the majo...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/12.2.161
更新日期:1983-06-01 00:00:00
abstract::The familial aggregation of chronic bronchitis and obstructive airways disease was investigated in a propositus population of 430 persons aged 45-54 years and 1340 of their first (1 degree), second (2degrees) and third (3 degrees ) order relatives. All subjects were screened in their homes using a modified British MRC...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/7.1.55
更新日期:1978-03-01 00:00:00
abstract:BACKGROUND:There is evidence that occupational factors that cause psychological strain can affect physical and mental health, but findings are not consistent. METHODS:Work satisfaction was used as a convenient global index of job-related psychological strain. Relationships with general, physical and emotional health, ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.1.98
更新日期:1994-02-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyq024
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Mortality in developing countries has multiple causes. Some of these causes are linked to climatic conditions that differ over the year. Data on season-specific mortality are sparse. METHODS:We analysed longitudinal data from a population of approximately 35,000 individuals in Burkina Faso. During the obser...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyi150
更新日期:2006-04-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.6.1000
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:The excess risk of fatal and non-fatal cerebrovascular disease in people from low socioeconomic positions is only partially explained by conventional cerebrovascular risk factors. This has led to the suggestion that poor psychosocial work environments provide important additional explanatory power. However, ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn373
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Small-for-gestational-age (SGA) birth is commonly used as a proxy for fetal growth restriction, but also includes constitutionally small infants. Genetic factors account for almost half of the risk of SGA birth. We estimated perinatal risks of SGA birth using both population-based and within-sibling analyses...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy196
更新日期:2019-02-01 00:00:00
abstract:Background:Infectious disease interventions are increasingly tested using cluster-randomized trials (CRTs). These trial settings tend to involve a set of sampling units, such as villages, whose geographic arrangement may present a contamination risk in treatment exposure. The most widely used approach for reducing cont...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy213
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Recent communications have argued that often it may not be appropriate to analyse cross-sectional studies of prevalent outcomes with logistic regression models. The purpose of this communication is to compare three methods that have been proposed for application to cross sectional studies: (1) a multiplicati...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.1.91
更新日期:1998-02-01 00:00:00
abstract::Interest has recently emerged about the increasing trend of pancreatic cancer mortality in Taiwan, particularly in the elderly. The mortality data of pancreatic cancer over the period 1971-1986 for males and females aged 40-84 in Taiwan were analysed using a log-linear Poisson model to examine the effects of age, cale...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.4.839
更新日期:1990-12-01 00:00:00
abstract:Background:It is known that perchlorate, nitrate and thiocyanate have the property of inhibiting sodium iodide symporter. Animal studies have suggested that these compounds, especially perchlorate, might also interfere with insulin secretion. However, the association between their exposure and diabetes risk is largely ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyx188
更新日期:2017-12-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyw335
更新日期:2017-08-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/9.2.111
更新日期:1980-06-01 00:00:00
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journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt115
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Accumulating evidence suggests that aspirin use may improve survival in cancer patients, however, for endometrial cancer, epidemiological evidence is limited and results are equivocal. In a nationwide cohort study, we examined the association between post-diagnostic low-dose aspirin use and endometrial cance...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz253
更新日期:2020-02-01 00:00:00
abstract::Interrupted time series (ITS) analysis is a valuable study design for evaluating the effectiveness of population-level health interventions that have been implemented at a clearly defined point in time. It is increasingly being used to evaluate the effectiveness of interventions ranging from clinical therapy to nation...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyw098
更新日期:2017-02-01 00:00:00
abstract::Geographical variations in the declining rates of ischaemic heart disease (IHD) mortality may provide clues about various environmental risk factors responsible as a mass influence on the population IHD rate. The rate of IHD decline in 18 of 21 NJ counties was 2 to 45% less than the USA national rate of decline. The o...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.1.26
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:In many western countries an increase in incidence of adenocarcinoma of the oesophagus and/or gastric cardia have been reported. The aim of this study was to describe and compare trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in several areas of Europe, 1968-1995, using Eurocim (a...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/29.4.645
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Anxiety or depression symptoms may increase the risk of developing asthma, and their interaction with obesity is not known. We aimed to assess the association of anxiety or depression symptoms and the joint association of these symptoms and obesity with incident asthma. METHODS:We conducted a prospective co...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt151
更新日期:2013-10-01 00:00:00
abstract::A serological survey of a random sample of 541 of the population of St Lucia was undertaken. The prevalence of antibodies to dengue, herpes virus, VZ, rotavirus, rubella and syphilis is described and compared with other communities. ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/8.4.327
更新日期:1979-12-01 00:00:00
abstract::Until recently, botulism was not recognized as an important public health problem in Taiwan. In 1986, an outbreak of type A foodborne botulism resulted in nine cases, two of them fatal. The vehicle in this outbreak was commercially preserved peanuts processed by an improperly equipped, unlicensed cannery. A single bat...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.4.899
更新日期:1988-12-01 00:00:00