Interrupted time series regression for the evaluation of public health interventions: a tutorial.

abstract：:The total duration of 'ovulatory activity' or 'ovulatory age' has been reported to be the strongest indicator of the risk of ovarian cancer. In the case-control study examined in this paper this variable was found to be a strong correlate of the risk of ovarian cancer. However, the finding that in older women the majo...

journal_title：International journal of epidemiology

authors： La Vecchia C,Franceschi S,Gallus G,Decarli A,Liberati A,Tognoni G

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Birthweight distributions among second-born infants depend on the birthweights of older siblings, with implications for weight-specific perinatal mortality. We wanted to study whether these relations were explained by socioeconomic levels, and to study time trends in a situation with decreasing perinatal mor...

journal_title：International journal of epidemiology

authors： Melve KK,Skjaerven R

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) mortality has more than halved in England since the 1980s, but there are few data on small-area trends. We estimated CVD mortality by ward in 5-year intervals between 1982 and 2006, and examined trends in relation to starting mortality, region and community deprivation. METHODS:...

journal_title：International journal of epidemiology

authors： Asaria P,Fortunato L,Fecht D,Tzoulaki I,Abellan JJ,Hambly P,de Hoogh K,Ezzati M,Elliott P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Neighbourhood socioeconomic status (SES) may affect rich and poor residents differentially. Two models are proposed. Model 1: living in a non-deprived neighbourhood is better for health because better collective material and social resources are available. Model 2: being poor (rich) relative to the neighbour...

journal_title：International journal of epidemiology

authors： Stafford M,Marmot M

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:In many countries, little is known about adult mortality rates. New innovations are necessary to develop reasonable estimates from available information. One readily available resource is household survey data. While birth histories collected in surveys have produced reasonable estimates of child mortality, ...

journal_title：International journal of epidemiology

authors： Gakidou E,Hogan M,Lopez AD

更新日期：2004-08-01 00:00:00

abstract：:We describe our experience in several settings, following a suggestion in 1983 to add questions on the smoking status of the deceased on the UK death certificate as an effective way to monitor the evolution of the smoking epidemic. In South Africa in 1997 and in Tianjin Municipality, China, in 2010, questions about th...

journal_title：International journal of epidemiology

authors： Sitas F,Bradshaw D,Egger S,Jiang G,Peto R

更新日期：2019-04-01 00:00:00

abstract：:The ratio of test statistics has been used to compare the efficiency of matched and unmatched designs, and stratified and pooled analyses for case-control studies. The index has been computed for a wide range of population conditions and it is concluded that (a) pooled analysis is always more efficient than stratified...

journal_title：International journal of epidemiology

authors： Choi BC,Howe GR

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:The impact and cost-effectiveness of couples' voluntary HIV counselling and testing (CVCT) has not been quantified in real-world settings. We quantify cost-per-HIV-infection averted by CVCT in Zambia from the donor's perspective. METHODS:From 2010 to 2016, CVCT was established in 73 Zambian government clini...

journal_title：International journal of epidemiology

authors： Wall KM,Inambao M,Kilembe W,Karita E,Vwalika B,Mulenga J,Parker R,Sharkey T,Sonti D,Tichacek A,Hunter E,Yohnka R,Abdallah JF,Thior I,Pulerwitz J,Allen S

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:A genetic component of early-onset lung cancer has been suggested. The role of metabolic gene polymorphisms has never been studied in young lung cancer cases. Phase 1 and Phase 2 gene polymorphisms are involved in tobacco carcinogens' metabolism and therefore in lung cancer risk. METHODS:The effect of metab...

journal_title：International journal of epidemiology

authors： Taioli E,Gaspari L,Benhamou S,Boffetta P,Brockmoller J,Butkiewicz D,Cascorbi I,Clapper ML,Dolzan V,Haugen A,Hirvonen A,Husgafvel-Pursiainen K,Kalina I,Kremers P,Le Marchand L,London S,Rannug A,Romkes M,Schoket B,Sei

更新日期：2003-02-01 00:00:00

abstract：:Specificity of association between putative risk factor and disease under study is important to inference on causality. Nevertheless many studies investigate mortality of a single disease without comparison with a control. Age-standardized proportional mortality ratios make single disease studies into case-control stu...

journal_title：International journal of epidemiology

authors： West RR

更新日期：1991-12-01 00:00:00

abstract：:The completeness of cancer registration in the IKL (Integraal Kankercentrum Limburg) cancer registry, Limburg, the Netherlands, was evaluated for the years 1988-1990 by means of the independent case ascertainment method. This study was performed in co-operation with the Registration Network of Family Practices (RNFP) ...

journal_title：International journal of epidemiology

authors： Schouten LJ,Höppener P,van den Brandt PA,Knottnerus JA,Jager JJ

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-beta1 (TGFbeta1) is a multifunctional signalling molecule with a wide array of roles. Animal experiments suggest that TGFbeta1 plays a biphasic role in carcinogenesis by protecting against the early formation of benign epithelial growths, but promoting malignant transformation of t...

journal_title：International journal of epidemiology

authors： Sparks R,Bigler J,Sibert JG,Potter JD,Yasui Y,Ulrich CM

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The genetic basis of several familial cancers including breast and colon cancers has been identified recently. The occurrence of multiple cancers in one individual is also suggestive of a genetic predisposition. To evaluate inherited predisposition in pancreatic cancer we compared the clinical data of pancre...

journal_title：International journal of epidemiology

authors： Gerdes B,Ziegler A,Ramaswamy A,Wild A,Langer P,Bartsch DK

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to analyse misclassification of height, weight and body mass index (BMI), derived from mail questionnaires, and its dependency on socioeconomic factors. METHODS:A random sample of 4442 adults aged 18-84 years, living in Stockholm county, Sweden, were in 1984-1985 asked about th...

journal_title：International journal of epidemiology

authors： Boström G,Diderichsen F

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:We examined the effect of a large reduction in the price of alcohol that occurred in Finland in 2004 on alcohol-related and all-cause mortality, and mortality due to cardiovascular diseases (CVDs) from which alcohol-attributable cases were excluded. METHODS:Time series intervention analysis modelling was ap...

journal_title：International journal of epidemiology

authors： Herttua K,Mäkelä P,Martikainen P

更新日期：2011-04-01 00:00:00

abstract：:Mortality among male employees was studied in a chromium chemical production plant, part of which was rebuilt in 1950-51 and the remainder in 1960, to reduce exposure to chromium bearing dusts. Of 2 101 employees initially employed between 1945 and 1974 and having worked at least 90 days, the vital status of 88% was a...

journal_title：International journal of epidemiology

authors： Hayes RB,Lilienfeld AM,Snell LM

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The long-term effects of infant vitamin D supplementation and status are unclear since there have been few controlled intervention trials and these have been small and contradictory. The Delhi Infant Vitamin D Supplementation (DIVIDS) trial found that supplementation of low-birthweight term infants with one ...

journal_title：International journal of epidemiology

authors： Trilok-Kumar G,Kaur M,Rehman AM,Arora H,Rajput MM,Chugh R,Kurpad A,Sachdev HS,Filteau S

更新日期：2015-06-01 00:00:00

abstract：Background:Medication adherence is frequently suboptimal in adults with chronic diseases, resulting in negative consequences. Motivational interviewing (MI) is a collaborative conversational style for strengthening a person's motivation and commitment to change. We aimed to assess whether MI interventions are effective...

journal_title：International journal of epidemiology

authors： Zomahoun HTV,Guénette L,Grégoire JP,Lauzier S,Lawani AM,Ferdynus C,Huiart L,Moisan J

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:In Sri Lanka, the major malaria vector Anopheles culicifacies breeds in pools formed in streams and river beds and it is likely that people living close to such breeding sites are at higher risk of malaria than people living further away. This study was done to quantify the importance of house location relat...

journal_title：International journal of epidemiology

authors： Van Der Hoek W,Konradsen F,Amerasinghe PH,Perera D,Piyaratne MK,Amerasinghe FP

更新日期：2003-04-01 00:00:00

abstract：:Two controlled, double blind field trials of a non-living promastigote vaccine against New World Cutaneous Leishmaniasis (NWCL) were conducted in 1981 and 1983 in Brazil. Brazilian Army conscripts were randomly assigned to the vaccine or placebo groups and tested during their training in the Amazon jungle, a high risk...

journal_title：International journal of epidemiology

authors： Antunes CM,Mayrink W,Magalhaes PA,Costa CA,Melo MN,Dias M,Michalick MS,Williams P,Lima AO,Vieira JB

更新日期：1986-12-01 00:00:00

abstract：:The EURODEM re-analyses of 11 case-control studies of Alzheimer's disease imply that familial aggregation of dementia, Down's syndrome, and parkinsonism occurs more frequently in Alzheimer's disease than in matched controls. Prior history of head trauma, hypothyroidism, and depression also occurs in higher frequency a...

journal_title：International journal of epidemiology

authors： Kokmen E

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Not every leprosy patient is equally effective in transmitting Mycobacterium leprae. We studied the spatial distribution of infection (using seropositivity as a marker) in the population to identify which disease characteristics of leprosy patients are important in transmission. METHODS:Clinical data and bl...

journal_title：International journal of epidemiology

authors： Bakker MI,Hatta M,Kwenang A,Faber WR,van Beers SM,Klatser PR,Oskam L

更新日期：2004-12-01 00:00:00

abstract：:Geoffrey Rose's 1985 paper, Sick individuals and sick populations, continues to spark debate and discussion. Since this original publication, there have been two notable challenges to Rose's population strategy of prevention. First, identification of high-risk individuals has improved considerably in accuracy, which s...

journal_title：International journal of epidemiology

authors： McLaren L,McIntyre L,Kirkpatrick S

更新日期：2010-04-01 00:00:00

abstract：:Samples of East African tribesmen from two separate locations were compared with respect to a number of anthropometric, cardiovascular and biochemical variables. The major finding was a large, significant difference in mean triglyceride levels between the groups (0.97 vs. 0.67 mmol/l; p less than 0.001), the mean plas...

journal_title：International journal of epidemiology

authors： Robinson D,Day J

更新日期：1986-06-01 00:00:00

abstract：:There is increasing recognition that the concepts traditionally taught by epidemiologists are essential for all medical graduates, most of whom will be clinicians, and not just for the minority who will specialize in population-based disciplines. This paper presents the recommendations of a Canadian conference which c...

journal_title：International journal of epidemiology

authors： Jenicek M,Fletcher RH

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:In a pilot study for the European Prospective Investigation into Cancer and Nutrition (EPIC) a modification of the Baecke questionnaire on physical activity was tested for repeatability and relative validity in a population of 134 men and women aged 20-70 years. METHODS:For the assessment of repeatability P...

journal_title：International journal of epidemiology

authors： Pols MA,Peeters PH,Bueno-De-Mesquita HB,Ocké MC,Wentink CA,Kemper HC,Collette HJ

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Complicated HIV transmission dynamics make it unclear how to design and interpret results from community-randomized controlled trials (CRCT) of interventions to prevent infection. METHODS:Mathematical modelling was used to investigate the effectiveness of interventions to prevent HIV transmission aimed at h...

journal_title：International journal of epidemiology

authors： Hallett TB,Garnett GP,Mupamberiyi Z,Gregson S

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:To determine the presence of interaction in epidemiologic research, typically a product term is added to the regression model. In linear regression, the regression coefficient of the product term reflects interaction as departure from additivity. However, in logistic regression it refers to interaction as de...

journal_title：International journal of epidemiology

authors： Knol MJ,van der Tweel I,Grobbee DE,Numans ME,Geerlings MI

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:We conducted this combined analysis of available data from studies with information on this issue to clarify the association between Trichomonas vaginalis infection and cervical neoplasia. METHODS:We performed MEDLINE searches (1966-1993) using the key words and phrases 'trichomonas vaginitis' and 'neoplasm...

journal_title：International journal of epidemiology

authors： Zhang ZF,Begg CB

更新日期：1994-08-01 00:00:00

abstract：:To describe secular trends in pneumonia hospitalizations in the Bronx, New York City from 1982-1986, we analysed all cases with a discharge diagnosis of pneumonia, excluding Pneumocystis carinii pneumonia (PCP), for Bronx residents by age, sex, neighbourhood, and length of stay (N = 21,822). Hospital deaths from PCP a...

journal_title：International journal of epidemiology

authors： Drucker E,Webber MP,McMaster P,Vermund SH

更新日期：1989-12-01 00:00:00