Abstract:
:The EURODEM re-analyses of 11 case-control studies of Alzheimer's disease imply that familial aggregation of dementia, Down's syndrome, and parkinsonism occurs more frequently in Alzheimer's disease than in matched controls. Prior history of head trauma, hypothyroidism, and depression also occurs in higher frequency among patients with Alzheimer's disease. Exposure to a series of other medical conditions and environmental toxins was not significant. The association between Alzheimer's disease and maternal age remains unclear.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Kokmen Edoi
10.1093/ije/20.supplement_2.s65subject
Has Abstractpub_date
1991-01-01 00:00:00pages
S65-7eissn
0300-5771issn
1464-3685journal_volume
20 Suppl 2pub_type
杂志文章abstract::In a population-based cohort study in Southern Brazil, 87.3% of 5914 liveborn infants were followed for over 12 months. The 215 infant deaths occurring in this cohort were studied in relation to birthweight, gestational age and socioeconomic status. Causes of death were ascertained through the review of case notes and...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.2.239
更新日期:1987-06-01 00:00:00
abstract::Using data from seven malformation monitoring systems around the world, the feasibility of monitoring fresh dominant mutations using skeletal dysplasias was explored. Based on a total of over 9.5 million births, 1500 infants with skeletal dysplasias were identified (16 per 100,000). In spite of efforts to get exact di...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.1.107
更新日期:1993-02-01 00:00:00
abstract::The attributable risk for invasive cervical cancer in the US and Italian populations has been estimated in relation to main 'aetiological' factors (number of sexual partners, age at first intercourse, parity, oral contraceptive use and smoking) and history of Pap smear using data from two case-control studies conducte...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.3.539
更新日期:1990-09-01 00:00:00
abstract::Involvement of adult Ixodes persulcatus ticks in the transmission of Lyme disease in Hailin County, Heilongjiang Province, China, is reported. In 1986 from April through August adult I. persulcatus was the dominant tick in this endemic area with an infection rate of 43% for the Lyme disease spirochaete, Borrelia burgd...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.4.1061
更新日期:1990-12-01 00:00:00
abstract::The European Atherosclerosis Research Study--EARS--is a multicentre collaborative project sponsored by the European Community. Its main objective is to study, in young people, the biological expression of a paternal history of premature acute myocardial infarction (AMI) and the relative share of heredity and environme...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/23.3.465
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:Mother's ethnicity is associated with her baby's birthweight and risk of perinatal mortality. Given the close relation between birthweight and perinatal mortality, we explored whether ethnic differences in birthweight explain ethnic differences in perinatal mortality. METHODS:Data on all births to mothers b...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/31.3.654
更新日期:2002-06-01 00:00:00
abstract::A serological survey of 300 Israeli intravenous drug addicts in 1988-1989, showed a 2.3% prevalence of antibodies to human immunodeficiency virus (HIV), very similar to the finding of a previous study (2%) performed in the same population in 1986. Travel and drug injection abroad continue to be the most significant pr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.3.561
更新日期:1992-06-01 00:00:00
abstract::In an effort to search for causes of malnutrition in the urban environment to guide intervention efforts, a study of more than 2000 mother/child pairs was conducted in Kinshasa, Zaire. Under the auspices of the Zairian National Nutrition Planning Center a representative sample of a large lower class urban population w...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.3.556
更新日期:1988-09-01 00:00:00
abstract::To determine whether mortality from asthma in Japan has increased, and to examine the age-, sex-, and race-specific mortality rates from this disease and their secular trends in both Japan and the US, vital statistics from 1979 through 1988 were studied. Overall, rates were highest among Japanese and decreased from 19...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/23.1.143
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Uncontrolled confounding by personal exposures like smoking can limit the inferential power of occupational cohort studies. We developed and demonstrate a refinement of an existing type of sensitivity analysis, indirect adjustment, for evaluating the potential magnitude of confounding by alcohol and tobacco....
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh151
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Trisomy 18 (Edwards' syndrome, T18) is the second most common trisomy in man. We describe 118 children with regular T18 who were ascertained clinically and cytogenetically in the Kuwait Medical Genetics Centre during 1980-1997. METHODS:Ascertainment of T18 cases was performed shortly after birth. Chromosoma...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/28.4.711
更新日期:1999-08-01 00:00:00
abstract::The relationship between risk of cervical neoplasia and various sociodemographic, reproductive and sexual characteristics was studied in 126 women (cases) with an abnormal Papanicolaou test finding and 1914 controls seen at the same clinic in which cases were detected but showing no evidence of cervical neoplasia. All...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/15.4.477
更新日期:1986-12-01 00:00:00
abstract::This discussion of sexually transmitted diseases (STDs) in less developed countries covers incidence/prevalence, antimicrobial resistance, sequelae, future trends, and new opportunities for STD control -- technological changes, health service changes, and social and political changes. For most countries, current, pop...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/14.4.505
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:Mycobacterium leprae (M. leprae) soluble antigen (MLSA) reagents have been developed with the aim of finding a reagent, comparable to tuberculin, which could identify individuals infected with the leprosy bacillus. They have yet to be evaluated fully in human populations. METHODS:More than 15000 individuals...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.4.713
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:Undernutrition is associated with an increased risk of death among young children in developing countries. Infant and child nutritional status and mortality were monitored in a rural area of Casamance, Senegal. METHODS:Analysis of weight measurements taken at 3-24 months of age during routine growth monitor...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh174
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Epidemiology in Latin America, as in the rest of the world, has been developed for the purpose of contributing towards understanding the causes and determinants of the phenomena of health and disease in specific contexts. However, in that continent it has specific characteristics. METHODS:The paper explores...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/dyh113
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Recently, using a counterfactual framework, a causal mediation analysis has been formalized to decompose the total effect of a time-fixed exposure on an outcome into four components that can be loosely defined as being components due to mediation only, interaction only, mediated interaction and neither. The ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy252
更新日期:2019-08-01 00:00:00
abstract::In both seasonal and inter-town variation, the mortality from ischaemic heart disease in England and Wales in 1969-71 is very highly correlated with temperature. Also in the inter-town variation, IHD mortality is highly correlated with rainfall and with socio-economic index. It is postulated that the same mechanism of...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/5.2.195
更新日期:1976-06-01 00:00:00
abstract:Background:This paper investigates trends in suicide rate, the reasons for and means of suicide and the occupation of deceased, to prioritize suicide prevention activities in India and to highlight the limitations to data quality for surveillance. Methods:Data available in the public domain from the National Crimes Re...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyw113
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Bundling, which consists of wrapping an infant for prolonged periods in a sheepskin cover after dried cow dung is applied, is a common and apparently unique practice limited to the rural, mountainous regions of Northern Pakistan. The practice is initiated at various ages during the neonatal period. Its poten...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.4.879
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Identifying mild cognitive impairment (MCI) in midlife could improve early identification of Alzheimer's disease (AD). Also, AD is highly heritable, but the heritability of MCI has not been established. We estimated prevalence rates, association with premorbid general cognitive ability (GCA) and heritability...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt242
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Many European countries have in recent decades reported growing socioeconomic differentials in mortality. While these trends have usually paralleled high unemployment and increasing income disparities, Sweden had low unemployment and narrowing income differences. This study describes trends, 1961-1990, in to...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.4.782
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Little is known about the relationship between physical functional health and long-term risk of coronary heart disease (CHD) independently of known risk factors in a general population. METHODS:Men and women aged 40-79 years at baseline who completed a health and lifestyle questionnaire and attended a healt...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyq061
更新日期:2010-08-01 00:00:00
abstract::A matched case-control study among cervical cancer patients in Denmark was conducted to evaluate the possible influence of radiation therapy on leukaemia risk. Among 25718 women treated between 1943-1977, 27 cases of leukaemia occurred one or more years after diagnosis. Four controls were matched to each case on age, ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.3.363
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND:Since 1997, an unexpected 2-5-fold increase in the incidence of pertussis has been reported in Poland in comparison with the previous 10 years, although the introduction of the diphtheria-tetanus-pertussis (DTP) vaccination in 1960 reduced the incidence of pertussis approximately 100-fold in the 1980s. The a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh012
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:The prevalence of obesity has increased rapidly in most developed countries in the last decades, and this rise is now spreading to developing countries. Childhood obesity is also increasing. The UK government has set a target to halt the rise in childhood obesity by 2010. Dietary recommendations are a centra...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/dyl208
更新日期:2006-12-01 00:00:00
abstract:Background:We studied associations of number of daily cigarettes in the first trimester with placental weight and birthweight in women who smoked throughout pregnancy, and in women who stopped smoking after the first trimester. Methods:We included all women with delivery of a singleton in Norway (n = 698 891) during 1...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy110
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:This study aims to evaluate the contribution of the reduction in major cardiovascular diseases (CVD), malignant neoplasms (MN), accidents and AIDS mortality to the gains in life expectancy observed during the decade 1985-1994, as well as to calculate and compare the potential gains due to the partial or tota...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/28.5.905
更新日期:1999-10-01 00:00:00
abstract:Background:Interventions to mitigate fuel poverty and particularly energy efficiency façade retrofitting (EEFR) have demonstrated positive impacts on health but the impacts of EEFR interventions on cold-related mortality have not been studied in depth. We evaluated the impact of EEFR interventions in Barcelona on the a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyw335
更新日期:2017-08-01 00:00:00
abstract::Cirrhosis mortality death rates in Ontario for ages 20 and over declined from a high of 9.3 per 100,000 in 1911 to a low of 5.6 per 100,000 in 1919 (p less than 0.001) and after a 17-year period of relative stability, rose steadily to a high of 19.7 per 100,000 in 1975 (p less than 0.0001) and then declined to 13.3 pe...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.1.199
更新日期:1991-03-01 00:00:00