Cohort Profile: Longitudinal Study of Adult Health (ELSA-Brasil).

Abstract:

:Chronic diseases are a global problem, yet information on their determinants is generally scant in low- and middle-income countries. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information regarding the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes, in one such setting. At Visit 1, we enrolled 15 105 civil servants from predefined universities or research institutes. Baseline assessment (2008-10) included detailed interviews and measurements to assess social and biological determinants of health, as well as various clinical and subclinical conditions related to diabetes, cardiovascular diseases and mental health. A second visit of interviews and examinations is under way (2012-14) to enrich the assessment of cohort exposures and to detect initial incident events. Annual surveillance has been conducted since 2009 for the ascertainment of incident events. Biological samples (sera, plasma, urine and DNA) obtained at both visits have been placed in long-term storage. Baseline data are available for analyses, and collaboration via specific research proposals directed to study investigators is welcome.

journal_name

Int J Epidemiol

authors

Schmidt MI,Duncan BB,Mill JG,Lotufo PA,Chor D,Barreto SM,Aquino EM,Passos VM,Matos SM,Molina Mdel C,Carvalho MS,Bensenor IM

doi

10.1093/ije/dyu027

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

68-75

issue

1

eissn

0300-5771

issn

1464-3685

pii

dyu027

journal_volume

44

pub_type

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