Craving is associated with smoking relapse: findings from three prospective studies.

abstract：:Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...

journal_title：Experimental and clinical psychopharmacology

authors： Gruber SA,Silveri MM,Dahlgren MK,Yurgelun-Todd D

更新日期：2011-06-01 00:00:00

abstract：:It is proposed that potential drug cues are evaluated preattentively, are prioritized, and subsequently trigger somatovisceral, behavioral, and cognitive responses. Throughout, this information processing is subjected to automatized attentional and interpretative biases. These processes can enhance subjective awarenes...

journal_title：Experimental and clinical psychopharmacology

authors： Ryan F

更新日期：2002-05-01 00:00:00

abstract：:Cigarette smoking is highly prevalent among patients who are being treated for opioid-dependence, yet there have been limited scientific efforts to promote smoking cessation in this population. Contingency management (CM) is a behavioral treatment that provides monetary incentives contingent upon biochemical evidence ...

journal_title：Experimental and clinical psychopharmacology

authors： Dunn KE,Saulsgiver KA,Sigmon SC

更新日期：2011-02-01 00:00:00

abstract：:The accurate assessment of nicotine withdrawal is important theoretically and clinically. A 28-item scale, the Wisconsin Smoking Withdrawal Scale, was developed that contains 7 reliable subscales tapping the major symptom elements of the nicotine withdrawal syndrome. Coefficients alpha for the subscales range from .75...

journal_title：Experimental and clinical psychopharmacology

authors： Welsch SK,Smith SS,Wetter DW,Jorenby DE,Fiore MC,Baker TB

更新日期：1999-11-01 00:00:00

abstract：:Drug cue reactivity is theoretically and clinically important. The modified Stroop task has been widely used to assess attention capture by drug cues (attentional bias). Attentional bias to drug cues is assumed to reflect the incentive value of those cues, but this has not been directly tested. The authors examined wh...

journal_title：Experimental and clinical psychopharmacology

authors： Waters AJ,Carter BL,Robinson JD,Wetter DW,Lam CY,Kerst W,Cinciripini PM

更新日期：2009-08-01 00:00:00

abstract：:Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Tapscott BE,Krishnan-Sarin S

更新日期：2016-04-01 00:00:00

abstract：:Prevalence of heavy alcohol use remain high, and daily marijuana use is at an all-time high in young adults. As perceptions of drug effects may guide risky decision making, understanding subjective feelings for alcohol and marijuana use is critical. Existing laboratory-based and diary metrics (0-100 rating of "how dru...

journal_title：Experimental and clinical psychopharmacology

authors： Linden-Carmichael AN,Masters LD,Lanza ST

更新日期：2020-12-01 00:00:00

abstract：:Varenicline reduces drinking in people with alcohol use disorder, but little is known about the mechanisms underlying this effect. Varenicline targets α4β2 and α7 nicotinic acetylcholine receptors, which are associated with several cognitive functions such as working memory. Varenicline may improve drinking outcomes b...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,McKee SA

更新日期：2018-02-01 00:00:00

abstract：:When 2 stimuli that occasion cocaine self-administration are presented in compound, their ability to increase cocaine-reinforced operant responding is substantially enhanced. The goal of the present experiment was to determine whether stimulus compounding could produce analogous enhancements of a classically condition...

journal_title：Experimental and clinical psychopharmacology

authors： Panlilio LV,Weiss SJ,Schindler CW

更新日期：2000-02-01 00:00:00

abstract：:The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

journal_title：Experimental and clinical psychopharmacology

authors： Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

更新日期：2011-12-01 00:00:00

abstract：:Insulin receptors are present in brain areas that are involved in the control of hunger and satiety, and intranasal insulin is assumed to have an anorexigenic effect. This known influence of insulin on satiety encouraged us to investigate the effect of intranasal insulin on feeding-related behaviors. The aim of the cu...

journal_title：Experimental and clinical psychopharmacology

authors： Rodriguez-Raecke R,Sommer M,Brünner YF,Müschenich FS,Sijben R

更新日期：2020-08-01 00:00:00

abstract：:The review article "Regulation of Drug Taking by Sensitization and Habituation" by F. K. McSweeney, E. S. Murphy, and B. P. Kowal introduces 2 basic principles of behavior, sensitization and habituation, into a comprehensive model for studying drug intake and drug addiction. A key assumption of the model is that the r...

journal_title：Experimental and clinical psychopharmacology

authors： Rowlett JK

更新日期：2005-08-01 00:00:00

abstract：:Smoking-related cues tend to produce urges and cardiac responses in smokers. This reactivity has been assumed to reflect prior classical conditioning. However, little direct evidence exists supporting the notion that environmental cues can be classically conditioned to cigarette smoking. In this study, 8 smokers recei...

journal_title：Experimental and clinical psychopharmacology

authors： Lazev AB,Herzog TA,Brandon TH

更新日期：1999-02-01 00:00:00

abstract：:Heavy smokers (N = 408, smoking more than 25 cigarettes/day) were randomized to receive high-dose (25 mg) or standard-dose (15 mg) nicotine patch therapy delivered during the daytime only (16 hr) for a period of 6 weeks. Treatment effects of each dose were similar. The percentages of participants not smoking at 2-, 6-...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Davis L,Strausberg L,Varady A

更新日期：1999-08-01 00:00:00

abstract：:In Experiment 1, the effect of repeated injections of 2.5, 5.0, or 10.0 mg/kg of chlordiazepoxide (CDP) on food intake and body weight was studied in rats on an activity anorexia (AA) regimen. For several days before CDP testing began, rats lived in activity wheels and had one 60-min meal per day. During CDP testing, ...

journal_title：Experimental and clinical psychopharmacology

authors： Lett BT,Grant VL,Koh MT,Parsons JF

更新日期：1998-11-01 00:00:00

abstract：:Adolescent brains are particularly susceptible to the rewarding properties of risky decisions in social contexts. Individual differences in genetic influences on dopamine transmission moderate neural outcome processing of risky decisions and may exert pronounced effects on adolescent risk-taking behavior (RTB) and cor...

journal_title：Experimental and clinical psychopharmacology

authors： Webber TA,Soder HE,Potts GF,Park JY,Bornovalova MA

更新日期：2017-02-01 00:00:00

abstract：:This study targeted poly-drug (cocaine plus heroin) abstinence among buprenorphine-maintained participants with a 12-week voucher-based reinforcement therapy (VBRT) phase versus a yoked control condition. Baseline levels of cocaine and heroin use were significant predictors of treatment outcome, regardless of treatmen...

journal_title：Experimental and clinical psychopharmacology

authors： Downey KK,Helmus TC,Schuster CR

更新日期：2000-05-01 00:00:00

abstract：:The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...

journal_title：Experimental and clinical psychopharmacology

authors： Boucart M,Waucquier N,Michael GA,Libersa C

更新日期：2007-02-01 00:00:00

abstract：:W. J. Lynch and M. E. Carroll (2001) suggested 3 processes that contribute to the regulation of drug intake over time when drugs serve as reinforcers. The commentator suggests that none of these processes are necessary for drugs to function as reinforcers and hence are either secondary or superfluous to the study of d...

journal_title：Experimental and clinical psychopharmacology

authors： Woods JH

更新日期：2001-05-01 00:00:00

abstract：:The authors investigated the effects of a laboratory stressor task on rapid initial orienting and delayed disengagement aspects of attentional bias for alcohol-related cues in social drinkers (N = 58). Participants were randomly allocated to receive a stress induction or control manipulation before completing a visual...

journal_title：Experimental and clinical psychopharmacology

authors： Field M,Quigley M

更新日期：2009-10-01 00:00:00

abstract：:In this study, crack/cocaine-dependent (CD) and non-drug-using matched control (MC) participants were presented with hypothetical immediate and delayed rewards, with 16 delay conditions ranging from 5 min to 25 years. All participants were presented with hypothetical monetary rewards; however, the CD group was also pr...

journal_title：Experimental and clinical psychopharmacology

authors： Coffey SF,Gudleski GD,Saladin ME,Brady KT

更新日期：2003-02-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants known to adversely impact human health. Ortho-substituted PCBs affect the nervous system, including the brain dopaminergic system. The reinforcing effects of psychostimulants are typically modulated via the dopaminergic system, so this study used ...

journal_title：Experimental and clinical psychopharmacology

authors： Miller MM,Meyer AE,Sprowles JL,Sable HJ

更新日期：2017-04-01 00:00:00

abstract：:Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...

journal_title：Experimental and clinical psychopharmacology

authors： Lawyer SR,Schoepflin F,Green R,Jenks C

更新日期：2011-08-01 00:00:00

abstract：:Lapses within the first 2 weeks of a smoking cessation attempt are strongly associated with a return to regular smoking (S. L. Kenford et al., 1994). Unfortunately, little is known about how to prevent an initial lapse from progressing to a full relapse, and presently there are no validated lapse-responsive therapeuti...

journal_title：Experimental and clinical psychopharmacology

authors： Juliano LM,Houtsmuller EJ,Stitzer ML

更新日期：2006-11-01 00:00:00

abstract：:The present study investigated the effects of chronic pre-exposure to methamphetamine on sexual motivation and performance in male Japanese quail. Quail were pre-exposed to methamphetamine (1.0 or 3.0 mg/kg ip) or saline (ip) once daily for 10 days and locomotor activity was measured. After a 10 day washout period, se...

journal_title：Experimental and clinical psychopharmacology

authors： Bolin BL,Akins CK

更新日期：2009-02-01 00:00:00

abstract：:Female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than on any other drug. Additionally, female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than their male counterparts, despite no cons...

journal_title：Experimental and clinical psychopharmacology

authors： Lejuez CW,Bornovalova MA,Reynolds EK,Daughters SB,Curtin JJ

更新日期：2007-04-01 00:00:00

abstract：:The relationship between nicotine abstinence and panic onset is still not well understood and the role of catastrophic misinterpretation, as possible moderator or mediator of this relationship, is unknown. We tested whether nicotine abstinence influences the response to a CO₂ panic challenge and whether catastrophic m...

journal_title：Experimental and clinical psychopharmacology

authors： Cosci F,Ibrahim HM,Nannini A,Schruers K

更新日期：2015-12-01 00:00:00

abstract：:Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases...

journal_title：Experimental and clinical psychopharmacology

authors： Chang HY,Tseng PT,Stubbs B,Chu CS,Li DJ,Fornaro M,Carvalho A,Solmi M,Veronese N,Vieta E,Chen TY,Chen YW,Lin PY,Chow PC

更新日期：2017-10-01 00:00:00

abstract：:Cocaine dependence constitutes a significant public health concern. This randomized, double-blind, placebo-controlled trial tested a novel approach to reducing cocaine use among cocaine-dependent individuals with d-cycloserine, a drug known to enhance learning and some learning-based therapies. Urine samples and cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Johnson MW,Bruner NR,Johnson PS,Silverman K,Berry MS

更新日期：2020-04-01 00:00:00

abstract：:A series of experiments in rats explored the possibility that D3/D2 dopamine receptors are involved in behaviors that might be related to compulsion. A series of D3/D2 agonists and antagonists were shown to elicit yawning (D3-receptor mediated) and its inhibition (D2-receptor mediated). In rats with histories of cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Woods JH

更新日期：2008-12-01 00:00:00