Effects of varenicline on cognitive performance in heavy drinkers: Dose-response effects and associations with drinking outcomes.

abstract：:In this study, crack/cocaine-dependent (CD) and non-drug-using matched control (MC) participants were presented with hypothetical immediate and delayed rewards, with 16 delay conditions ranging from 5 min to 25 years. All participants were presented with hypothetical monetary rewards; however, the CD group was also pr...

journal_title：Experimental and clinical psychopharmacology

authors： Coffey SF,Gudleski GD,Saladin ME,Brady KT

更新日期：2003-02-01 00:00:00

abstract：:W. J. Lynch and M. E. Carroll (2001) suggested 3 processes that contribute to the regulation of drug intake over time when drugs serve as reinforcers. The commentator suggests that none of these processes are necessary for drugs to function as reinforcers and hence are either secondary or superfluous to the study of d...

journal_title：Experimental and clinical psychopharmacology

authors： Woods JH

更新日期：2001-05-01 00:00:00

abstract：:Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether delay discounting changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects who completed discounting assessments at ba...

journal_title：Experimental and clinical psychopharmacology

authors： Landes RD,Christensen DR,Bickel WK

更新日期：2012-08-01 00:00:00

abstract：:Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxet...

journal_title：Experimental and clinical psychopharmacology

authors： Minami H,Kahler CW,Bloom EL,Prince MA,Abrantes AM,Strong DR,Niaura R,Miller IW,Palm Reed KM,Price LH,Brown RA

更新日期：2014-10-01 00:00:00

abstract：:Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...

journal_title：Experimental and clinical psychopharmacology

authors： Cheng J,Lu Y,Han X,González-Vallejo C,Sui N

更新日期：2012-10-01 00:00:00

abstract：:The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

journal_title：Experimental and clinical psychopharmacology

authors： Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

更新日期：2011-12-01 00:00:00

abstract：:There are important individual differences in acute subjective responses to alcohol, which have often been assessed using self-report measures. There is also evidence of meaningful between-persons variation in alcohol's disinhibiting effects on behavior, such that some individuals become more impaired on tasks of inhi...

journal_title：Experimental and clinical psychopharmacology

authors： Quinn PD,Fromme K

更新日期：2016-04-01 00:00:00

abstract：:Evidence suggests that smoking to cope among adolescents is associated with a number of problematic outcomes (e.g., greater smoking frequency, higher rates of dependence). It is thus imperative to better understand factors that may increase the likelihood of smoking to cope among adolescents. Research suggests anxiety...

journal_title：Experimental and clinical psychopharmacology

authors： Bilsky SA,Feldner MT,Knapp AA,Rojas SM,Leen-Feldner EW

更新日期：2016-06-01 00:00:00

abstract：:Using data from 4 smoking cessation trials conducted from 1988 to 2000, the authors investigated whether men are more successful than women in quitting smoking. Odds ratios indicated that the abstinence rates were not significantly different for men and women. Thus, there may be little value to diverting research fund...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Varady A,Kraemer HC

更新日期：2002-08-01 00:00:00

abstract：:Prescription stimulant misuse (PSM) is common in young adult college students, at over 10% in the past year, and it is associated with other substance use and risk behaviors. Research focused on the real-time drivers of PSM is absent, impeding prevention and intervention. This research aimed to fill that gap by examin...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Buckner JD,Klare DL,Wade LR,Benedetto N

更新日期：2020-05-28 00:00:00

abstract：:The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

journal_title：Experimental and clinical psychopharmacology

authors： Zhou J,Heim D,Monk R,Levy A,Pollard P

更新日期：2018-06-01 00:00:00

abstract：:It is proposed that potential drug cues are evaluated preattentively, are prioritized, and subsequently trigger somatovisceral, behavioral, and cognitive responses. Throughout, this information processing is subjected to automatized attentional and interpretative biases. These processes can enhance subjective awarenes...

journal_title：Experimental and clinical psychopharmacology

authors： Ryan F

更新日期：2002-05-01 00:00:00

abstract：:The authors investigated several features of polydrug use in rats. Heroin and cocaine were self-administered following responses on different levers, with only 1 drug and 1 lever available on alternate days of training. Four doses of each drug (heroin: 25, 50, 100, and 200 microg/kg/infusion; cocaine: 0.25, 0.5, 1, an...

journal_title：Experimental and clinical psychopharmacology

authors： Leri F,Stewart J

更新日期：2001-08-01 00:00:00

abstract：:Estrogen increases and progesterone decreases the acquisition and reinstatement of cocaine-seeking behavior in female rats. Here estrogen and progesterone were studied for their effects on the escalation of cocaine self-administration in female rats. The rats received ovariectomy (OVX) or sham (SH) surgery and were tr...

journal_title：Experimental and clinical psychopharmacology

authors： Larson EB,Anker JJ,Gliddon LA,Fons KS,Carroll ME

更新日期：2007-10-01 00:00:00

abstract：:Female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than on any other drug. Additionally, female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than their male counterparts, despite no cons...

journal_title：Experimental and clinical psychopharmacology

authors： Lejuez CW,Bornovalova MA,Reynolds EK,Daughters SB,Curtin JJ

更新日期：2007-04-01 00:00:00

abstract：:In the United States, the Food and Drug Administration (FDA) has initiated a public dialogue about reducing the nicotine content of cigarettes. A reduced-nicotine standard could increase withdrawal symptoms among current smokers. We examined the impact of switching smokers to cigarettes that varied in nicotine content...

journal_title：Experimental and clinical psychopharmacology

authors： Dermody SS,McClernon FJ,Benowitz N,Luo X,Tidey JW,Smith TT,Vandrey R,Hatsukami D,Donny EC

更新日期：2018-06-01 00:00:00

abstract：:A retrospective study was conducted to examine aripiprazole's effectiveness and safety in a naturalistic treatment setting in both inpatients and outpatients affected by schizophrenia and other psychotic disorders. All patients with schizophrenia, schizoaffective and delusional disorders, and schizoid and schizotypal ...

journal_title：Experimental and clinical psychopharmacology

authors： Di Lorenzo R,Amoretti A,Forghieri M,Fiorini F,Genedani S,Rigatelli M

更新日期：2007-12-01 00:00:00

abstract：:Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...

journal_title：Experimental and clinical psychopharmacology

authors： Mendelson J,Flower K,Pletcher MJ,Galloway GP

更新日期：2008-10-01 00:00:00

abstract：:The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differe...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Girdler SS,Shapiro D,Jarvik ME

更新日期：1998-02-01 00:00:00

abstract：:Sprague-Dawley (Rattus norvegicus) rats were trained in a drug discrimination task using the state-dependent interoceptive stimulus attributes of cocaine's delayed or rebound effects (CDE) versus "normal" basal homeostasis. Rats were injected with either 32 mg/kg cocaine or equivalent volumes of saline (SAL), subcutan...

journal_title：Experimental and clinical psychopharmacology

authors： Gauvin DV,Vanecek SA,Baird TJ,Briscoe RJ,Vallett M,Carl KL,Wasielewski JA,Holloway FA

更新日期：1998-08-01 00:00:00

abstract：:This review outlines the development and use of placebo cigarettes in smoking research. Research on effects of smoking has been disadvantaged by the lack of an adequate placebo condition. Recently, tobacco-based denicotinized cigarettes have been used in smoking research to distinguish effects of smoking due to the de...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson ML,Houtsmuller EJ,Moolchan ET,Pickworth WB

更新日期：2000-08-01 00:00:00

abstract：:Two studies were conducted to determine the anger-attenuating effects of nicotine as a function of trait hostility. The 1st study examined the effects of nicotine on diary ratings of anger during a 24-hr period in a natural setting in 30 smokers and 30 nonsmokers. Participants took part in 2 monitoring sessions involv...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Shapiro D,Jarvik ME

更新日期：1999-11-01 00:00:00

abstract：:Smokers are highly reactive to smoking-related cues that are directly linked, or most proximal, to actual smoking behavior (e.g., lit cigarettes). However, over the course of smoking, proximal cues may not be the only stimuli to become strongly associated with smoking. Distal cues, such as the environments in which sm...

journal_title：Experimental and clinical psychopharmacology

authors： Conklin CA,Robin N,Perkins KA,Salkeld RP,McClernon FJ

更新日期：2008-06-01 00:00:00

abstract：:Goods-based contingency management interventions (e.g., those using vouchers or prizes as incentives) have demonstrated efficacy in reducing cocaine use, but cost has limited dissemination to community clinics. Recent research suggests that development of a cash-based contingency management approach may improve treatm...

journal_title：Experimental and clinical psychopharmacology

authors： Vandrey R,Bigelow GE,Stitzer ML

更新日期：2007-08-01 00:00:00

abstract：:Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...

journal_title：Experimental and clinical psychopharmacology

authors： Kleykamp BA,Griffiths RR,Mintzer MZ

更新日期：2010-02-01 00:00:00

abstract：:Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Tapscott BE,Krishnan-Sarin S

更新日期：2016-04-01 00:00:00

abstract：:Six features of the report are commented on. First, the Therapeutic Workplace intervention described in the report represents a creative and promising new approach to drug abuse treatment. Second, to the author's knowledge, it represents the first intervention that has been shown in a randomized clinical trial to sign...

journal_title：Experimental and clinical psychopharmacology

authors： Higgins ST

更新日期：2001-02-01 00:00:00

abstract：:A series of experiments in rats explored the possibility that D3/D2 dopamine receptors are involved in behaviors that might be related to compulsion. A series of D3/D2 agonists and antagonists were shown to elicit yawning (D3-receptor mediated) and its inhibition (D2-receptor mediated). In rats with histories of cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Woods JH

更新日期：2008-12-01 00:00:00

abstract：:Although marijuana is the most commonly used illicit drug in the United States, it is not established whether withdrawal from chronic use results in a clinically significant abstinence syndrome. The present study was conducted to characterize symptoms associated with marijuana withdrawal following chronic use during a...

journal_title：Experimental and clinical psychopharmacology

authors： Kouri EM,Pope HG Jr

更新日期：2000-11-01 00:00:00

abstract：:Drug abuse and impulsive choice are related in humans. In female rats, impulsive choice predicted the rate of acquisition of IV cocaine self-administration. The objectives of the present experiments were to: (a) compare impulsive choice in males and females, (b) extend previous research on impulsive choice and acquisi...

journal_title：Experimental and clinical psychopharmacology

authors： Perry JL,Nelson SE,Carroll ME

更新日期：2008-04-01 00:00:00