Drug-induced reinstatement to heroin and cocaine seeking: a rodent model of relapse in polydrug use.

abstract：:Addiction is characterized as a chronic debilitating disease. One devastating feature of addiction is the susceptibility of relapse (40-60%) after stretches of abstinence. One theory that may account for relapse suggests that drug cues (e.g., paraphernalia) may increase stress hormones, and this may prompt relapse. Re...

journal_title：Experimental and clinical psychopharmacology

authors： Rice BA,Eaton SE,Prendergast MA,Akins CK

更新日期：2018-08-01 00:00:00

abstract：:Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...

journal_title：Experimental and clinical psychopharmacology

authors： Lawyer SR,Schoepflin F,Green R,Jenks C

更新日期：2011-08-01 00:00:00

abstract：:The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

journal_title：Experimental and clinical psychopharmacology

authors： Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

更新日期：2011-12-01 00:00:00

abstract：:Delay discounting, the devaluation of delayed reinforcers, is one defining behavioral economic characteristic of cigarette smokers. Attempts at abstinence by smokers that result in relapse are conceptualized in this framework as preference reversals. Despite preference reversals being predicted by delay discounting mo...

journal_title：Experimental and clinical psychopharmacology

authors： Pope DA,Poe L,Stein JS,Snider SE,Bianco AG,Bickel WK

更新日期：2019-02-01 00:00:00

abstract：:Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether delay discounting changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects who completed discounting assessments at ba...

journal_title：Experimental and clinical psychopharmacology

authors： Landes RD,Christensen DR,Bickel WK

更新日期：2012-08-01 00:00:00

abstract：:Cocaine dependence constitutes a significant public health concern. This randomized, double-blind, placebo-controlled trial tested a novel approach to reducing cocaine use among cocaine-dependent individuals with d-cycloserine, a drug known to enhance learning and some learning-based therapies. Urine samples and cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Johnson MW,Bruner NR,Johnson PS,Silverman K,Berry MS

更新日期：2020-04-01 00:00:00

abstract：:Relative to intravenous drug self-administration, locomotor activity is easier to measure with high throughput, particularly in mice. Therefore its potential to predict differences in self-administration between genotypes (e.g., targeted mutations, recombinant inbred strains) is appealing, but such predictive value is...

journal_title：Experimental and clinical psychopharmacology

authors： Thomsen M,Caine SB

更新日期：2011-10-01 00:00:00

abstract：:Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases...

journal_title：Experimental and clinical psychopharmacology

authors： Chang HY,Tseng PT,Stubbs B,Chu CS,Li DJ,Fornaro M,Carvalho A,Solmi M,Veronese N,Vieta E,Chen TY,Chen YW,Lin PY,Chow PC

更新日期：2017-10-01 00:00:00

abstract：:The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

journal_title：Experimental and clinical psychopharmacology

authors： Zhou J,Heim D,Monk R,Levy A,Pollard P

更新日期：2018-06-01 00:00:00

abstract：:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a struct...

journal_title：Experimental and clinical psychopharmacology

authors： Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

更新日期：2002-11-01 00:00:00

abstract：:Nicotine administration has been found to enhance performance on tasks of selective attention. It has been proposed that efficient attentional filtering depends on the successful inhibition of distracting information. In the work reported here, a negative priming paradigm was adopted to test whether smoking enhanced t...

journal_title：Experimental and clinical psychopharmacology

authors： Rodway P,Dienes Z,Schepman A

更新日期：2000-02-01 00:00:00

abstract：:This review outlines the development and use of placebo cigarettes in smoking research. Research on effects of smoking has been disadvantaged by the lack of an adequate placebo condition. Recently, tobacco-based denicotinized cigarettes have been used in smoking research to distinguish effects of smoking due to the de...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson ML,Houtsmuller EJ,Moolchan ET,Pickworth WB

更新日期：2000-08-01 00:00:00

abstract：:Evidence suggests that smoking to cope among adolescents is associated with a number of problematic outcomes (e.g., greater smoking frequency, higher rates of dependence). It is thus imperative to better understand factors that may increase the likelihood of smoking to cope among adolescents. Research suggests anxiety...

journal_title：Experimental and clinical psychopharmacology

authors： Bilsky SA,Feldner MT,Knapp AA,Rojas SM,Leen-Feldner EW

更新日期：2016-06-01 00:00:00

abstract：:The nonmedical use of prescription drugs is a widely recognized public health issue, and young adults are particularly vulnerable to their use. Behavioral economic drug purchase tasks capture an individual's strength of desire and motivation for a particular drug. We examined young adult prescription drug purchase and...

journal_title：Experimental and clinical psychopharmacology

authors： Pickover AM,Messina BG,Correia CJ,Garza KB,Murphy JG

更新日期：2016-02-01 00:00:00

abstract：:The psycholinguistic analysis of client-counselor interactions indicates that how individuals talk about their substance use is associated with treatment outcome. However, the processes by which client speech influences out-of-session behaviors have not been clearly delineated. This study investigated the relationship...

journal_title：Experimental and clinical psychopharmacology

authors： Carpenter KM,Amrhein PC,Bold KW,Mishlen K,Levin FR,Raby WN,Evans SM,Foltin RW,Nunes EV

更新日期：2016-04-01 00:00:00

abstract：:Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxet...

journal_title：Experimental and clinical psychopharmacology

authors： Minami H,Kahler CW,Bloom EL,Prince MA,Abrantes AM,Strong DR,Niaura R,Miller IW,Palm Reed KM,Price LH,Brown RA

更新日期：2014-10-01 00:00:00

abstract：:A burgeoning literature supports a link between alcohol use and panic-spectrum problems (e.g., panic attacks, disorder) among adolescents, but the direction of influence has yet to be properly examined. From a theoretical perspective, panic-spectrum problems may increase risk for problematic drinking via affect regula...

journal_title：Experimental and clinical psychopharmacology

authors： Blumenthal H,Cloutier RM,Zamboanga BL,Bunaciu L,Knapp AA

更新日期：2015-10-01 00:00:00

abstract：:Drug abuse and obesity are serious public health problems. Dopamine plays a central role in mediating the reinforcing effects of drugs and food. Prolonged use of drugs is known to alter the function and/or sensitivity of many neurotransmitter systems, including dopamine; however, the impact of consuming foods high in ...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Chen Y,Tschumi C,Rush EL,Mensah A,Koek W,France CP

更新日期：2015-08-01 00:00:00

abstract：:Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,Fillmore MT,Milich R

更新日期：2012-04-01 00:00:00

abstract：:Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...

journal_title：Experimental and clinical psychopharmacology

authors： Mendelson J,Flower K,Pletcher MJ,Galloway GP

更新日期：2008-10-01 00:00:00

abstract：:When 2 stimuli that occasion cocaine self-administration are presented in compound, their ability to increase cocaine-reinforced operant responding is substantially enhanced. The goal of the present experiment was to determine whether stimulus compounding could produce analogous enhancements of a classically condition...

journal_title：Experimental and clinical psychopharmacology

authors： Panlilio LV,Weiss SJ,Schindler CW

更新日期：2000-02-01 00:00:00

abstract：:Delay discounting, reflected in the tendency to prefer immediate rewards over delayed rewards, is associated with most forms of problematic substance use. When assessed multiple times to examine within-individual changes, for example, following acute drug administration or an intervention, shifts in delay discounting ...

journal_title：Experimental and clinical psychopharmacology

authors： Kuang J,Milhorn H,Stuppy-Sullivan A,Jung S,Yi R

更新日期：2018-10-01 00:00:00

abstract：:The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...

journal_title：Experimental and clinical psychopharmacology

authors： Boucart M,Waucquier N,Michael GA,Libersa C

更新日期：2007-02-01 00:00:00

abstract：:The effects of using several nicotine replacement treatments on self-reported withdrawal symptoms and side effects during 2-day periods of smoking cessation, with 5 days of ad lib smoking between cessation days, were evaluated. Participants (N = 18) experienced the following conditions: nicotine gum, 24-hr patch, 16-h...

journal_title：Experimental and clinical psychopharmacology

authors： Leischow SJ,Valente SN,Hill AL,Otte PS,Aickin M,Holden T,Kligman E,Cook G

更新日期：1997-02-01 00:00:00

abstract：:Social learning theory considers self-efficacy as a causal factor in behavior change. However, in line with behavioral theory, recent clinical research suggests self-efficacy ratings may reflect, rather than cause, behavior change. To test these two disparate views, self-efficacy was related to actual smoking abstinen...

journal_title：Experimental and clinical psychopharmacology

authors： Perkins KA,Parzynski C,Mercincavage M,Conklin CA,Fonte CA

更新日期：2012-02-01 00:00:00

abstract：:In a combined sample of more than 2600 smokers, immediate postcessation craving is shown to be prospectively associated with smokers' ability to maintain abstinence. Relapse is strikingly rapid among those reporting high levels of craving following cessation. More than 32% of those with high craving scores relapsed wi...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP

更新日期：1997-05-01 00:00:00

abstract：:The present study primarily sought to (a) determine the effects of environmental context on subjective ratings of craving for alcohol and caffeinated alcohol beverages (CAB) and (b) test inhibitory control, a state behavioral aspect of impulsivity, as a mediator of the association between context and craving in a samp...

journal_title：Experimental and clinical psychopharmacology

authors： Stamates AL,Lau-Barraco C

更新日期：2017-12-01 00:00:00

abstract：:This study examined prevalence and patterns of co-use of opioids and cocaine in regular users of illicit opioids (N = 729) recruited from 5 Canadian cities. Fifty-seven percent (n = 417) reported having used both opioids and cocaine in the month and week preceding the interview; of these, 73% (n = 304) were able to id...

journal_title：Experimental and clinical psychopharmacology

authors： Leri F,Stewart J,Fischer B,Jürgen R,Marsh DC,Brissette S,Bruneau J,El-Guebaly N,Noël L,Tyndall MW,Wild TC

更新日期：2005-11-01 00:00:00

abstract：:The affectively valenced scripts used by S. Tiffany (1990) suggest that different scripts produce relatively equivalent levels of cue reactivity, although it is unclear if these laboratory findings generalize to clinical samples. In this study, cessation-motivated smokers were tested 7 days before they tried to quit s...

journal_title：Experimental and clinical psychopharmacology

authors： Shadel WG,Niaura R,Abrams DB,Goldstein MG,Rohsenow DJ,Sirota AD,Monti PM

更新日期：1998-05-01 00:00:00

abstract：:The review article "Regulation of Drug Taking by Sensitization and Habituation" by F. K. McSweeney, E. S. Murphy, and B. P. Kowal introduces 2 basic principles of behavior, sensitization and habituation, into a comprehensive model for studying drug intake and drug addiction. A key assumption of the model is that the r...

journal_title：Experimental and clinical psychopharmacology

authors： Rowlett JK

更新日期：2005-08-01 00:00:00