Impulsive choice as a predictor of acquisition of IV cocaine self- administration and reinstatement of cocaine-seeking behavior in male and female rats.

abstract：:Insulin receptors are present in brain areas that are involved in the control of hunger and satiety, and intranasal insulin is assumed to have an anorexigenic effect. This known influence of insulin on satiety encouraged us to investigate the effect of intranasal insulin on feeding-related behaviors. The aim of the cu...

journal_title：Experimental and clinical psychopharmacology

authors： Rodriguez-Raecke R,Sommer M,Brünner YF,Müschenich FS,Sijben R

更新日期：2020-08-01 00:00:00

abstract：:Heavy drinking among college students is a public health concern in part due to the accessibility of alcohol and promotions such as "happy hours," which discount the price of alcohol. In addition, consuming alcohol at unregulated off-campus parties may result in greater alcohol consumption, higher blood alcohol concen...

journal_title：Experimental and clinical psychopharmacology

authors： Morrell MN,Reed DD,Martinetti MP

更新日期：2020-03-19 00:00:00

abstract：:Smoking rates are higher in U.S. soldiers than civilians, with combat-experienced soldiers particularly at risk for heavy smoking (≥20 cigarettes/day). While heavy smoking is correlated with mental health symptoms in civilian samples, the extent to which these symptoms, background variables, and unit climate (self-rep...

journal_title：Experimental and clinical psychopharmacology

authors： Lopez AA,Toblin RL,Riviere LA,Lee JD,Adler AB

更新日期：2018-06-01 00:00:00

abstract：:The social environment plays a critical role in determining the likelihood that an individual will use drugs or will develop a drug use disorder. Recent evidence obtained from preclinical studies reveals that proximal social factors (i.e., those factors that are immediately present at the time of drug exposure) exert ...

journal_title：Experimental and clinical psychopharmacology

authors： Strickland JC,Smith MA

更新日期：2014-02-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with complex genetic inheritance. Findings suggest a role for brain-derived neurotrophic factor (BDNF) in OCD, but reports are limited. Here we studied the association of BDNF polymorphisms rs6265 and rs2883187 with OCD and its clinical charact...

journal_title：Experimental and clinical psychopharmacology

authors： Abdolhosseinzadeh S,Alizadeh N,Shams J,Asadi S,Ahmadiani A

更新日期：2020-04-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are ubiquitous environmental toxicants known to adversely impact human health. Ortho-substituted PCBs affect the nervous system, including the brain dopaminergic system. The reinforcing effects of psychostimulants are typically modulated via the dopaminergic system, so this study used ...

journal_title：Experimental and clinical psychopharmacology

authors： Miller MM,Meyer AE,Sprowles JL,Sable HJ

更新日期：2017-04-01 00:00:00

abstract：:In the United States, the Food and Drug Administration (FDA) has initiated a public dialogue about reducing the nicotine content of cigarettes. A reduced-nicotine standard could increase withdrawal symptoms among current smokers. We examined the impact of switching smokers to cigarettes that varied in nicotine content...

journal_title：Experimental and clinical psychopharmacology

authors： Dermody SS,McClernon FJ,Benowitz N,Luo X,Tidey JW,Smith TT,Vandrey R,Hatsukami D,Donny EC

更新日期：2018-06-01 00:00:00

abstract：:In Experiment 1, the effect of repeated injections of 2.5, 5.0, or 10.0 mg/kg of chlordiazepoxide (CDP) on food intake and body weight was studied in rats on an activity anorexia (AA) regimen. For several days before CDP testing began, rats lived in activity wheels and had one 60-min meal per day. During CDP testing, ...

journal_title：Experimental and clinical psychopharmacology

authors： Lett BT,Grant VL,Koh MT,Parsons JF

更新日期：1998-11-01 00:00:00

abstract：:Despite depressive symptoms being very common among patients seeking treatment for cocaine dependence, few studies have examined the effects of depressive symptoms on cocaine outpatient treatment outcomes, and there is even less research in the context of Contingency Management (CM). The purpose of this study was to a...

journal_title：Experimental and clinical psychopharmacology

authors： García-Fernández G,Secades-Villa R,García-Rodríguez O,Peña-Suárez E,Sánchez-Hervás E

更新日期：2013-12-01 00:00:00

abstract：:Delayed reward discounting (DRD) is a behavioral economic measure of impulsivity that has been consistently associated with addiction. It has also been identified as a promising addiction endophenotype, linking specific sources of genetic variation to individual risk. A challenge in the studies to date is that levels ...

journal_title：Experimental and clinical psychopharmacology

authors： MacKillop J,Gray JC,Weafer J,Sanchez-Roige S,Palmer AA,de Wit H

更新日期：2019-02-01 00:00:00

abstract：:Smoking is among the most important health behaviors linked to premature death and disability among the Latinx population. Yet there is limited understanding of whether transdiagnostic factors like anxiety sensitivity may help explain smoking expectancies among Spanish-speaking Latinx smokers. The present investigatio...

journal_title：Experimental and clinical psychopharmacology

authors： Zvolensky MJ,Bakhshaie J,Shepherd JM,Garey L,Peraza N,Viana AG,Brown JT,Brown RA

更新日期：2019-12-01 00:00:00

abstract：:Sprague-Dawley (Rattus norvegicus) rats were trained in a drug discrimination task using the state-dependent interoceptive stimulus attributes of cocaine's delayed or rebound effects (CDE) versus "normal" basal homeostasis. Rats were injected with either 32 mg/kg cocaine or equivalent volumes of saline (SAL), subcutan...

journal_title：Experimental and clinical psychopharmacology

authors： Gauvin DV,Vanecek SA,Baird TJ,Briscoe RJ,Vallett M,Carl KL,Wasielewski JA,Holloway FA

更新日期：1998-08-01 00:00:00

abstract：:A burgeoning literature supports a link between alcohol use and panic-spectrum problems (e.g., panic attacks, disorder) among adolescents, but the direction of influence has yet to be properly examined. From a theoretical perspective, panic-spectrum problems may increase risk for problematic drinking via affect regula...

journal_title：Experimental and clinical psychopharmacology

authors： Blumenthal H,Cloutier RM,Zamboanga BL,Bunaciu L,Knapp AA

更新日期：2015-10-01 00:00:00

abstract：:When 2 stimuli that occasion cocaine self-administration are presented in compound, their ability to increase cocaine-reinforced operant responding is substantially enhanced. The goal of the present experiment was to determine whether stimulus compounding could produce analogous enhancements of a classically condition...

journal_title：Experimental and clinical psychopharmacology

authors： Panlilio LV,Weiss SJ,Schindler CW

更新日期：2000-02-01 00:00:00

abstract：:Two studies were conducted to determine the anger-attenuating effects of nicotine as a function of trait hostility. The 1st study examined the effects of nicotine on diary ratings of anger during a 24-hr period in a natural setting in 30 smokers and 30 nonsmokers. Participants took part in 2 monitoring sessions involv...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Shapiro D,Jarvik ME

更新日期：1999-11-01 00:00:00

abstract：:The affectively valenced scripts used by S. Tiffany (1990) suggest that different scripts produce relatively equivalent levels of cue reactivity, although it is unclear if these laboratory findings generalize to clinical samples. In this study, cessation-motivated smokers were tested 7 days before they tried to quit s...

journal_title：Experimental and clinical psychopharmacology

authors： Shadel WG,Niaura R,Abrams DB,Goldstein MG,Rohsenow DJ,Sirota AD,Monti PM

更新日期：1998-05-01 00:00:00

abstract：:The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effe...

journal_title：Experimental and clinical psychopharmacology

authors： Baldwin RL,Chelonis JJ,Flake RA,Edwards MC,Feild CR,Meaux JB,Paule MG

更新日期：2004-02-01 00:00:00

abstract：:Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...

journal_title：Experimental and clinical psychopharmacology

authors： Gruber SA,Silveri MM,Dahlgren MK,Yurgelun-Todd D

更新日期：2011-06-01 00:00:00

abstract：:Cigarette smoking is highly prevalent among patients who are being treated for opioid-dependence, yet there have been limited scientific efforts to promote smoking cessation in this population. Contingency management (CM) is a behavioral treatment that provides monetary incentives contingent upon biochemical evidence ...

journal_title：Experimental and clinical psychopharmacology

authors： Dunn KE,Saulsgiver KA,Sigmon SC

更新日期：2011-02-01 00:00:00

abstract：:Antipsychotic polypharmacy refers to the clinical practice of treating a patient with two or more antipsychotic drugs concurrently. There is abundant evidence in the clinical literature that treatment with antipsychotic polypharmacy is associated with an increased prevalence of drug side effects compared with monother...

journal_title：Experimental and clinical psychopharmacology

authors： Boyda HN,Procyshyn RM,Tse L,Xu J,Jin CH,Wong D,Pang CC,Honer WG,Barr AM

更新日期：2013-04-01 00:00:00

abstract：:The authors investigated several features of polydrug use in rats. Heroin and cocaine were self-administered following responses on different levers, with only 1 drug and 1 lever available on alternate days of training. Four doses of each drug (heroin: 25, 50, 100, and 200 microg/kg/infusion; cocaine: 0.25, 0.5, 1, an...

journal_title：Experimental and clinical psychopharmacology

authors： Leri F,Stewart J

更新日期：2001-08-01 00:00:00

abstract：:Drug cue reactivity is theoretically and clinically important. The modified Stroop task has been widely used to assess attention capture by drug cues (attentional bias). Attentional bias to drug cues is assumed to reflect the incentive value of those cues, but this has not been directly tested. The authors examined wh...

journal_title：Experimental and clinical psychopharmacology

authors： Waters AJ,Carter BL,Robinson JD,Wetter DW,Lam CY,Kerst W,Cinciripini PM

更新日期：2009-08-01 00:00:00

abstract：:There are important individual differences in acute subjective responses to alcohol, which have often been assessed using self-report measures. There is also evidence of meaningful between-persons variation in alcohol's disinhibiting effects on behavior, such that some individuals become more impaired on tasks of inhi...

journal_title：Experimental and clinical psychopharmacology

authors： Quinn PD,Fromme K

更新日期：2016-04-01 00:00:00

abstract：:Alcohol use and risky single occasion drinking are common among adolescents and are associated with a higher risk of various negative social, physical, academic, or sexual consequences. Studies have shown that among college students, willingness to experience negative consequences is associated with a higher likelihoo...

journal_title：Experimental and clinical psychopharmacology

authors： Wicki M,Mallett KA,Delgrande Jordan M,Reavy R,Turrisi R,Archimi A,Kuntsche E

更新日期：2018-04-01 00:00:00

abstract：:Lapses within the first 2 weeks of a smoking cessation attempt are strongly associated with a return to regular smoking (S. L. Kenford et al., 1994). Unfortunately, little is known about how to prevent an initial lapse from progressing to a full relapse, and presently there are no validated lapse-responsive therapeuti...

journal_title：Experimental and clinical psychopharmacology

authors： Juliano LM,Houtsmuller EJ,Stitzer ML

更新日期：2006-11-01 00:00:00

abstract：:Six features of the report are commented on. First, the Therapeutic Workplace intervention described in the report represents a creative and promising new approach to drug abuse treatment. Second, to the author's knowledge, it represents the first intervention that has been shown in a randomized clinical trial to sign...

journal_title：Experimental and clinical psychopharmacology

authors： Higgins ST

更新日期：2001-02-01 00:00:00

abstract：:Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...

journal_title：Experimental and clinical psychopharmacology

authors： Lawyer SR,Schoepflin F,Green R,Jenks C

更新日期：2011-08-01 00:00:00

abstract：:The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differe...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Girdler SS,Shapiro D,Jarvik ME

更新日期：1998-02-01 00:00:00

abstract：:Substance use disorders and pathological gambling share similarities in terms of diagnostic criteria, epidemiology, and clinical course. However, relatively few studies have evaluated the efficacy of treatments for gambling disorders. As interest in pathological gambling grows, adaptation of effective treatments from ...

journal_title：Experimental and clinical psychopharmacology

authors： Petry NM

更新日期：2002-08-01 00:00:00

abstract：:Evidence suggests that smoking to cope among adolescents is associated with a number of problematic outcomes (e.g., greater smoking frequency, higher rates of dependence). It is thus imperative to better understand factors that may increase the likelihood of smoking to cope among adolescents. Research suggests anxiety...

journal_title：Experimental and clinical psychopharmacology

authors： Bilsky SA,Feldner MT,Knapp AA,Rojas SM,Leen-Feldner EW

更新日期：2016-06-01 00:00:00