Abstract:
:The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differences in nicotine's hypoalgesic actions, ratings of electrocutaneous stimulation were obtained from 30 male and 44 female smokers and nonsmokers under placebo and nicotine conditions. Nicotine increased the pain threshold and tolerance ratings of men but had no effect on the pain ratings of women. Among men, there was no effect of smoking history, suggesting that the changes in pain perception reflect a direct pain-inhibitory effect of nicotine rather than a relief from acute nicotine withdrawal. Nicotine had no effect on mood or task ratings, indicating that the antinociceptive effects observed were not due to nicotine's putative mood effects.
journal_name
Exp Clin Psychopharmacoljournal_title
Experimental and clinical psychopharmacologyauthors
Jamner LD,Girdler SS,Shapiro D,Jarvik MEdoi
10.1037//1064-1297.6.1.96subject
Has Abstractpub_date
1998-02-01 00:00:00pages
96-106issue
1eissn
1064-1297issn
1936-2293journal_volume
6pub_type
临床试验,杂志文章abstract::The accurate assessment of nicotine withdrawal is important theoretically and clinically. A 28-item scale, the Wisconsin Smoking Withdrawal Scale, was developed that contains 7 reliable subscales tapping the major symptom elements of the nicotine withdrawal syndrome. Coefficients alpha for the subscales range from .75...
journal_title:Experimental and clinical psychopharmacology
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journal_title:Experimental and clinical psychopharmacology
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journal_title:Experimental and clinical psychopharmacology
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doi:10.1037//1064-1297.6.2.179
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journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/pha0000058
更新日期:2016-02-01 00:00:00
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journal_title:Experimental and clinical psychopharmacology
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更新日期:2018-06-01 00:00:00
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更新日期:2018-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-12-01 00:00:00
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abstract::The social environment plays a critical role in determining the likelihood that an individual will use drugs or will develop a drug use disorder. Recent evidence obtained from preclinical studies reveals that proximal social factors (i.e., those factors that are immediately present at the time of drug exposure) exert ...
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abstract::Previous field research has shown that individuals consumed more alcohol and at a faster rate in environments paired with loud music. Theoretically, this effect has been linked to approach/avoidance accounts of how music influences arousal and mood, but no work has tested this experimentally. In the present study, fem...
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pub_type: 杂志文章
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abstract::Maternal smoking is a leading preventable cause of poor pregnancy outcomes and infant morbidity and mortality. Whereas pregnancy has been thought of as a "window of opportunity" when women are more motivated to change health behaviors such as smoking, only 20% of pregnant women quit smoking upon learning they are preg...
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pub_type: 杂志文章
doi:10.1037/1064-1297.14.2.165
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journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/pha0000344
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abstract::Smoking rates are higher in U.S. soldiers than civilians, with combat-experienced soldiers particularly at risk for heavy smoking (≥20 cigarettes/day). While heavy smoking is correlated with mental health symptoms in civilian samples, the extent to which these symptoms, background variables, and unit climate (self-rep...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/pha0000193
更新日期:2018-06-01 00:00:00
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journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
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更新日期:2010-02-01 00:00:00
abstract::The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
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更新日期:2007-02-01 00:00:00
abstract::Methylphenidate (MPH) is one of the most widely prescribed drugs for treating attention-deficit hyperactivity disorder. Previous research suggested that MPH is a reinforcer for rats, but not all of the manipulations to show that lever pressing is controlled by the contingency to obtain MPH have been examined. In Exper...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0019814
更新日期:2010-06-01 00:00:00
abstract::Despite depressive symptoms being very common among patients seeking treatment for cocaine dependence, few studies have examined the effects of depressive symptoms on cocaine outpatient treatment outcomes, and there is even less research in the context of Contingency Management (CM). The purpose of this study was to a...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
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更新日期:2013-12-01 00:00:00
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journal_title:Experimental and clinical psychopharmacology
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更新日期:2018-08-01 00:00:00
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journal_title:Experimental and clinical psychopharmacology
pub_type: 评论,杂志文章
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更新日期:2001-02-01 00:00:00
abstract::Heavy smokers (N = 408, smoking more than 25 cigarettes/day) were randomized to receive high-dose (25 mg) or standard-dose (15 mg) nicotine patch therapy delivered during the daytime only (16 hr) for a period of 6 weeks. Treatment effects of each dose were similar. The percentages of participants not smoking at 2-, 6-...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-08-01 00:00:00
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journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
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