Treatment of heroin-dependent poly-drug abusers with contingency management and buprenorphine maintenance.

abstract：:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a struct...

journal_title：Experimental and clinical psychopharmacology

authors： Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

更新日期：2002-11-01 00:00:00

abstract：:Sprague-Dawley (Rattus norvegicus) rats were trained in a drug discrimination task using the state-dependent interoceptive stimulus attributes of cocaine's delayed or rebound effects (CDE) versus "normal" basal homeostasis. Rats were injected with either 32 mg/kg cocaine or equivalent volumes of saline (SAL), subcutan...

journal_title：Experimental and clinical psychopharmacology

authors： Gauvin DV,Vanecek SA,Baird TJ,Briscoe RJ,Vallett M,Carl KL,Wasielewski JA,Holloway FA

更新日期：1998-08-01 00:00:00

abstract：:Varenicline reduces drinking in people with alcohol use disorder, but little is known about the mechanisms underlying this effect. Varenicline targets α4β2 and α7 nicotinic acetylcholine receptors, which are associated with several cognitive functions such as working memory. Varenicline may improve drinking outcomes b...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,McKee SA

更新日期：2018-02-01 00:00:00

abstract：:Repeated drug administration results in sensitization, tolerance, or no change in subsequent drug-induced alterations of motivated behaviors, such as intracranial self-stimulation (ICSS). For example, repeated mu-opioid agonist administration results in increased expression of mu agonist-induced facilitation of ICSS. ...

journal_title：Experimental and clinical psychopharmacology

authors： Faunce KE,Banks ML

更新日期：2020-02-01 00:00:00

abstract：:The present study primarily sought to (a) determine the effects of environmental context on subjective ratings of craving for alcohol and caffeinated alcohol beverages (CAB) and (b) test inhibitory control, a state behavioral aspect of impulsivity, as a mediator of the association between context and craving in a samp...

journal_title：Experimental and clinical psychopharmacology

authors： Stamates AL,Lau-Barraco C

更新日期：2017-12-01 00:00:00

abstract：:Some abused drugs have been reported to alter performance on naturalistic tasks such as driving and also on laboratory tasks. The performance effects of several drug classes were examined using a repeated measures design. Eight volunteers were administered 2 doses of ethanol, marijuana, amphetamine, hydromorphone, pen...

journal_title：Experimental and clinical psychopharmacology

authors： Pickworth WB,Rohrer MS,Fant RV

更新日期：1997-08-01 00:00:00

abstract：:There has been a dramatic rise in the consumption of glucose energy drinks (e.g., Amp, Monster, and Red Bull) in the past decade, particularly among high school and college students. However, little laboratory research has examined the acute objective and subjective effects of energy drinks. The purpose of this study ...

journal_title：Experimental and clinical psychopharmacology

authors： Howard MA,Marczinski CA

更新日期：2010-12-01 00:00:00

abstract：:In Experiment 1, the effect of repeated injections of 2.5, 5.0, or 10.0 mg/kg of chlordiazepoxide (CDP) on food intake and body weight was studied in rats on an activity anorexia (AA) regimen. For several days before CDP testing began, rats lived in activity wheels and had one 60-min meal per day. During CDP testing, ...

journal_title：Experimental and clinical psychopharmacology

authors： Lett BT,Grant VL,Koh MT,Parsons JF

更新日期：1998-11-01 00:00:00

abstract：:Smoking is among the most important health behaviors linked to premature death and disability among the Latinx population. Yet there is limited understanding of whether transdiagnostic factors like anxiety sensitivity may help explain smoking expectancies among Spanish-speaking Latinx smokers. The present investigatio...

journal_title：Experimental and clinical psychopharmacology

authors： Zvolensky MJ,Bakhshaie J,Shepherd JM,Garey L,Peraza N,Viana AG,Brown JT,Brown RA

更新日期：2019-12-01 00:00:00

abstract：:It is becoming increasingly evident that the sex of an organism is a critical determinant of responsiveness to opioid analgesics. However, the factors that determine the magnitude and direction of sex differences in opioid antinociception have not been fully elucidated. One factor that has received attention is the re...

journal_title：Experimental and clinical psychopharmacology

authors： Barrett AC

更新日期：2006-02-01 00:00:00

abstract：:Prevalence of heavy alcohol use remain high, and daily marijuana use is at an all-time high in young adults. As perceptions of drug effects may guide risky decision making, understanding subjective feelings for alcohol and marijuana use is critical. Existing laboratory-based and diary metrics (0-100 rating of "how dru...

journal_title：Experimental and clinical psychopharmacology

authors： Linden-Carmichael AN,Masters LD,Lanza ST

更新日期：2020-12-01 00:00:00

abstract：:Heavy smokers (N = 408, smoking more than 25 cigarettes/day) were randomized to receive high-dose (25 mg) or standard-dose (15 mg) nicotine patch therapy delivered during the daytime only (16 hr) for a period of 6 weeks. Treatment effects of each dose were similar. The percentages of participants not smoking at 2-, 6-...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Davis L,Strausberg L,Varady A

更新日期：1999-08-01 00:00:00

abstract：:Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...

journal_title：Experimental and clinical psychopharmacology

authors： Kleykamp BA,Griffiths RR,Mintzer MZ

更新日期：2010-02-01 00:00:00

abstract：:Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...

journal_title：Experimental and clinical psychopharmacology

authors： Gruber SA,Silveri MM,Dahlgren MK,Yurgelun-Todd D

更新日期：2011-06-01 00:00:00

abstract：:Goods-based contingency management interventions (e.g., those using vouchers or prizes as incentives) have demonstrated efficacy in reducing cocaine use, but cost has limited dissemination to community clinics. Recent research suggests that development of a cash-based contingency management approach may improve treatm...

journal_title：Experimental and clinical psychopharmacology

authors： Vandrey R,Bigelow GE,Stitzer ML

更新日期：2007-08-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with complex genetic inheritance. Findings suggest a role for brain-derived neurotrophic factor (BDNF) in OCD, but reports are limited. Here we studied the association of BDNF polymorphisms rs6265 and rs2883187 with OCD and its clinical charact...

journal_title：Experimental and clinical psychopharmacology

authors： Abdolhosseinzadeh S,Alizadeh N,Shams J,Asadi S,Ahmadiani A

更新日期：2020-04-01 00:00:00

abstract：:Binge drinking is frequently reported by young adults, despite being associated with a number of negative consequences. This type of heavy drinking is associated with deficits in many executive functions, including working memory. Poor working memory may contribute to increased alcohol use by limiting one's ability to...

journal_title：Experimental and clinical psychopharmacology

authors： Looby A,Norton-Baker M,Russell TD

更新日期：2018-08-01 00:00:00

abstract：:In this experiment, the observing-response procedure was adapted for use with drug self-administration. Rats' responding for oral ethanol was sometimes reinforced on a random-ratio schedule, whereas at other times it had no effect (i.e., extinction). Behavior producing stimuli associated with the otherwise unsignaled ...

journal_title：Experimental and clinical psychopharmacology

authors： Shahan TA

更新日期：2002-02-01 00:00:00

abstract：:Drug abuse and obesity are serious public health problems. Dopamine plays a central role in mediating the reinforcing effects of drugs and food. Prolonged use of drugs is known to alter the function and/or sensitivity of many neurotransmitter systems, including dopamine; however, the impact of consuming foods high in ...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Chen Y,Tschumi C,Rush EL,Mensah A,Koek W,France CP

更新日期：2015-08-01 00:00:00

abstract：:Dopamine acts through dopamine Type I receptors (comprising D1 and D5 subtypes) and dopamine Type II receptors (comprising D2, D3, and D4 subtypes). Intracranial self-stimulation (ICSS) is 1 experimental procedure that can be used to evaluate abuse-related effects of drugs targeting dopamine receptors. This study eval...

journal_title：Experimental and clinical psychopharmacology

authors： Lazenka MF,Legakis LP,Negus SS

更新日期：2016-06-01 00:00:00

abstract：:Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Tapscott BE,Krishnan-Sarin S

更新日期：2016-04-01 00:00:00

abstract：:Cocaine dependence constitutes a significant public health concern. This randomized, double-blind, placebo-controlled trial tested a novel approach to reducing cocaine use among cocaine-dependent individuals with d-cycloserine, a drug known to enhance learning and some learning-based therapies. Urine samples and cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Johnson MW,Bruner NR,Johnson PS,Silverman K,Berry MS

更新日期：2020-04-01 00:00:00

abstract：:Two studies were conducted to determine the anger-attenuating effects of nicotine as a function of trait hostility. The 1st study examined the effects of nicotine on diary ratings of anger during a 24-hr period in a natural setting in 30 smokers and 30 nonsmokers. Participants took part in 2 monitoring sessions involv...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Shapiro D,Jarvik ME

更新日期：1999-11-01 00:00:00

abstract：:The consumption of caffeine has become a growing concern, partially because of the withdrawal properties of the drug. The current study examined personality correlates of caffeine consumption and dependence in 60 university students. Self-report and behavioral measures of sensation seeking, impulsivity, and risk takin...

journal_title：Experimental and clinical psychopharmacology

authors： Jones HA,Lejuez CW

更新日期：2005-08-01 00:00:00

abstract：:Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...

journal_title：Experimental and clinical psychopharmacology

authors： Cheng J,Lu Y,Han X,González-Vallejo C,Sui N

更新日期：2012-10-01 00:00:00

abstract：:The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

journal_title：Experimental and clinical psychopharmacology

authors： Zhou J,Heim D,Monk R,Levy A,Pollard P

更新日期：2018-06-01 00:00:00

abstract：:The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effe...

journal_title：Experimental and clinical psychopharmacology

authors： Baldwin RL,Chelonis JJ,Flake RA,Edwards MC,Feild CR,Meaux JB,Paule MG

更新日期：2004-02-01 00:00:00

abstract：:Oxytocin has been shown to decrease cocaine taking and seeking in male rats, suggesting potential treatment efficacy for drug addiction. In the present study, we extended these findings to the assessment of cocaine seeking and taking in female rats. Further, we made direct comparisons of oxytocin's impact on cocaine i...

journal_title：Experimental and clinical psychopharmacology

authors： Leong KC,Zhou L,Ghee SM,See RE,Reichel CM

更新日期：2016-02-01 00:00:00

abstract：:Using data from 4 smoking cessation trials conducted from 1988 to 2000, the authors investigated whether men are more successful than women in quitting smoking. Odds ratios indicated that the abstinence rates were not significantly different for men and women. Thus, there may be little value to diverting research fund...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Varady A,Kraemer HC

更新日期：2002-08-01 00:00:00

abstract：:Research examining the role of pharmacological therapy in the treatment of children and adolescents with clinical disorders is growing. Clinical disorders that present with comorbid aggression can add a challenge to treatment. Child and adolescent neuropsychiatric disorders associated with aggression include attention...

journal_title：Experimental and clinical psychopharmacology

authors： Nevels RM,Dehon EE,Alexander K,Gontkovsky ST

更新日期：2010-04-01 00:00:00