The relations among personality, symptoms of alcohol and marijuana abuse, and symptoms of comorbid psychopathology: results from a community sample.

Abstract:

:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a structured diagnostic interview at age 21 years. Hierarchical regression analyses indicated that unique constellations of personality characteristics were associated with symptoms of alcohol abuse, marijuana abuse, APD, and internalizing disorders. For example, symptoms of alcohol abuse were associated with high Extraversion and low Conscientiousness, whereas symptoms of marijuana abuse were characterized by low Extraversion and high Openness to Experience. Findings have implications for models of the etiology and treatment of substance use and abuse.

authors

Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

doi

10.1037//1064-1297.10.4.425

keywords:

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

425-34

issue

4

eissn

1064-1297

issn

1936-2293

journal_volume

10

pub_type

杂志文章
  • Treatment of heroin-dependent poly-drug abusers with contingency management and buprenorphine maintenance.

    abstract::This study targeted poly-drug (cocaine plus heroin) abstinence among buprenorphine-maintained participants with a 12-week voucher-based reinforcement therapy (VBRT) phase versus a yoked control condition. Baseline levels of cocaine and heroin use were significant predictors of treatment outcome, regardless of treatmen...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.8.2.176

    authors: Downey KK,Helmus TC,Schuster CR

    更新日期:2000-05-01 00:00:00

  • Predicting college student prescription stimulant misuse: An analysis from ecological momentary assessment.

    abstract::Prescription stimulant misuse (PSM) is common in young adult college students, at over 10% in the past year, and it is associated with other substance use and risk behaviors. Research focused on the real-time drivers of PSM is absent, impeding prevention and intervention. This research aimed to fill that gap by examin...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000386

    authors: Schepis TS,Buckner JD,Klare DL,Wade LR,Benedetto N

    更新日期:2020-05-28 00:00:00

  • Aripiprazole: effectiveness and safety under naturalistic conditions.

    abstract::A retrospective study was conducted to examine aripiprazole's effectiveness and safety in a naturalistic treatment setting in both inpatients and outpatients affected by schizophrenia and other psychotic disorders. All patients with schizophrenia, schizoaffective and delusional disorders, and schizoid and schizotypal ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.15.6.569

    authors: Di Lorenzo R,Amoretti A,Forghieri M,Fiorini F,Genedani S,Rigatelli M

    更新日期:2007-12-01 00:00:00

  • Using a dependent schedule to measure risky choice in male rats: Effects of d-amphetamine, methylphenidate, and methamphetamine.

    abstract::Risky choice is the tendency to choose a large, uncertain reward over a small, certain reward, and is typically measured with probability discounting, in which the probability of obtaining the large reinforcer decreases across blocks of trials. One caveat to traditional procedures is that independent schedules are use...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000300

    authors: Yates JR,Prior NA,Chitwood MR,Day HA,Heidel JR,Hopkins SE,Muncie BT,Paradella-Bradley TA,Sestito AP,Vecchiola AN,Wells EE

    更新日期:2020-04-01 00:00:00

  • Correlates of current and heavy smoking among U.S. soldiers returning from combat.

    abstract::Smoking rates are higher in U.S. soldiers than civilians, with combat-experienced soldiers particularly at risk for heavy smoking (≥20 cigarettes/day). While heavy smoking is correlated with mental health symptoms in civilian samples, the extent to which these symptoms, background variables, and unit climate (self-rep...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000193

    authors: Lopez AA,Toblin RL,Riviere LA,Lee JD,Adler AB

    更新日期:2018-06-01 00:00:00

  • The efficacy and tolerability of paliperidone in mania of bipolar disorder: A preliminary meta-analysis.

    abstract::Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1037/pha0000148

    authors: Chang HY,Tseng PT,Stubbs B,Chu CS,Li DJ,Fornaro M,Carvalho A,Solmi M,Veronese N,Vieta E,Chen TY,Chen YW,Lin PY,Chow PC

    更新日期:2017-10-01 00:00:00

  • Effects of sequential fluoxetine and gender on prequit depressive symptoms, affect, craving, and quit day abstinence in smokers with elevated depressive symptoms: a growth curve modeling approach.

    abstract::Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxet...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0037156

    authors: Minami H,Kahler CW,Bloom EL,Prince MA,Abrantes AM,Strong DR,Niaura R,Miller IW,Palm Reed KM,Price LH,Brown RA

    更新日期:2014-10-01 00:00:00

  • A laboratory-based test of the relation between adolescent alcohol use and panic-relevant responding.

    abstract::A burgeoning literature supports a link between alcohol use and panic-spectrum problems (e.g., panic attacks, disorder) among adolescents, but the direction of influence has yet to be properly examined. From a theoretical perspective, panic-spectrum problems may increase risk for problematic drinking via affect regula...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000022

    authors: Blumenthal H,Cloutier RM,Zamboanga BL,Bunaciu L,Knapp AA

    更新日期:2015-10-01 00:00:00

  • Pre-adolescent alcohol expectancies: critical shifts and associated maturational processes.

    abstract::Children's alcohol expectancies shift in late childhood/early adolescence in ways thought to lead to increased risk for adolescent alcohol use. The precise nature of this shift and the maturational processes that may influence it remain to be clarified. To these ends, we compared expectancy endorsement by grade across...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0025373

    authors: Bekman NM,Goldman MS,Worley MJ,Anderson KG

    更新日期:2011-12-01 00:00:00

  • Attentional bias is associated with incentive-related physiological and subjective measures.

    abstract::Drug cue reactivity is theoretically and clinically important. The modified Stroop task has been widely used to assess attention capture by drug cues (attentional bias). Attentional bias to drug cues is assumed to reflect the incentive value of those cues, but this has not been directly tested. The authors examined wh...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0016658

    authors: Waters AJ,Carter BL,Robinson JD,Wetter DW,Lam CY,Kerst W,Cinciripini PM

    更新日期:2009-08-01 00:00:00

  • Impulsive choice as a predictor of acquisition of IV cocaine self- administration and reinstatement of cocaine-seeking behavior in male and female rats.

    abstract::Drug abuse and impulsive choice are related in humans. In female rats, impulsive choice predicted the rate of acquisition of IV cocaine self-administration. The objectives of the present experiments were to: (a) compare impulsive choice in males and females, (b) extend previous research on impulsive choice and acquisi...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.16.2.165

    authors: Perry JL,Nelson SE,Carroll ME

    更新日期:2008-04-01 00:00:00

  • Effect of methylphenidate on time perception in children with attention-deficit/hyperactivity disorder.

    abstract::The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effe...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037/1064-1297.12.1.57

    authors: Baldwin RL,Chelonis JJ,Flake RA,Edwards MC,Feild CR,Meaux JB,Paule MG

    更新日期:2004-02-01 00:00:00

  • Proximal versus distal cues to smoke: the effects of environments on smokers' cue-reactivity.

    abstract::Smokers are highly reactive to smoking-related cues that are directly linked, or most proximal, to actual smoking behavior (e.g., lit cigarettes). However, over the course of smoking, proximal cues may not be the only stimuli to become strongly associated with smoking. Distal cues, such as the environments in which sm...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.16.3.207

    authors: Conklin CA,Robin N,Perkins KA,Salkeld RP,McClernon FJ

    更新日期:2008-06-01 00:00:00

  • Opposing effects of dopamine D1- and D2-like agonists on intracranial self-stimulation in male rats.

    abstract::Dopamine acts through dopamine Type I receptors (comprising D1 and D5 subtypes) and dopamine Type II receptors (comprising D2, D3, and D4 subtypes). Intracranial self-stimulation (ICSS) is 1 experimental procedure that can be used to evaluate abuse-related effects of drugs targeting dopamine receptors. This study eval...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000067

    authors: Lazenka MF,Legakis LP,Negus SS

    更新日期:2016-06-01 00:00:00

  • Effects of acute pramipexole on male rats' preference for gambling-like rewards II.

    abstract::Pramipexole (PPX) is a dopamine agonist medication that has been implicated in the development of pathological gambling and other impulse control disorders. Johnson, Madden, Brewer, Pinkston, and Fowler (2011) reported that PPX increased male rats' preference for gambling-like rewards (those arranged according to a va...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0027117

    authors: Johnson PS,Madden GJ,Stein JS

    更新日期:2012-06-01 00:00:00

  • Characterizing nicotine withdrawal in pregnant cigarette smokers.

    abstract::Maternal smoking is a leading preventable cause of poor pregnancy outcomes and infant morbidity and mortality. Whereas pregnancy has been thought of as a "window of opportunity" when women are more motivated to change health behaviors such as smoking, only 20% of pregnant women quit smoking upon learning they are preg...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.14.2.165

    authors: Heil SH,Higgins ST,Mongeon JA,Badger GJ,Bernstein IM

    更新日期:2006-05-01 00:00:00

  • Psychopharmacology of aggression in children and adolescents with primary neuropsychiatric disorders: a review of current and potentially promising treatment options.

    abstract::Research examining the role of pharmacological therapy in the treatment of children and adolescents with clinical disorders is growing. Clinical disorders that present with comorbid aggression can add a challenge to treatment. Child and adolescent neuropsychiatric disorders associated with aggression include attention...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,评审

    doi:10.1037/a0018059

    authors: Nevels RM,Dehon EE,Alexander K,Gontkovsky ST

    更新日期:2010-04-01 00:00:00

  • The effects of cadmium contamination on the discriminative stimulus properties of cocaine and related drugs.

    abstract::Rats were exposed to a diet containing 100 ppm cadmium chloride or a control diet. At 52 days of exposure, rats were trained to discriminate between saline and 5 mg/kg cocaine injections. After acquisition training, successive substitution tests were conducted using cocaine, the indirect dopamine agonist d-amphetamine...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.7.2.90

    authors: Nation JR,Miller DK

    更新日期:1999-05-01 00:00:00

  • Temporal discounting in heroin-dependent patients: no sign effect, weaker magnitude effect, and the relationship with inhibitory control.

    abstract::Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0029657

    authors: Cheng J,Lu Y,Han X,González-Vallejo C,Sui N

    更新日期:2012-10-01 00:00:00

  • Is self-efficacy for smoking abstinence a cause of, or a reflection on, smoking behavior change?

    abstract::Social learning theory considers self-efficacy as a causal factor in behavior change. However, in line with behavioral theory, recent clinical research suggests self-efficacy ratings may reflect, rather than cause, behavior change. To test these two disparate views, self-efficacy was related to actual smoking abstinen...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0025482

    authors: Perkins KA,Parzynski C,Mercincavage M,Conklin CA,Fonte CA

    更新日期:2012-02-01 00:00:00

  • Pain inhibition, nicotine, and gender.

    abstract::The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differe...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.6.1.96

    authors: Jamner LD,Girdler SS,Shapiro D,Jarvik ME

    更新日期:1998-02-01 00:00:00

  • Alcohol and behavioral control: impaired response inhibition and flexibility in social drinkers.

    abstract::This study shows that a moderate dose of alcohol (0.62 g/kg) can impair cognitive processes controlling behavioral inhibition and flexibility (i.e., inhibiting one response and making a different one). Two groups of male social drinkers (n = 8) received alcohol or a placebo and performed two change tasks that required...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.8.3.387

    authors: Easdon CM,Vogel-Sprott M

    更新日期:2000-08-01 00:00:00

  • A behavioral economic analysis of the nonmedical use of prescription drugs among young adults.

    abstract::The nonmedical use of prescription drugs is a widely recognized public health issue, and young adults are particularly vulnerable to their use. Behavioral economic drug purchase tasks capture an individual's strength of desire and motivation for a particular drug. We examined young adult prescription drug purchase and...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000052

    authors: Pickover AM,Messina BG,Correia CJ,Garza KB,Murphy JG

    更新日期:2016-02-01 00:00:00

  • Effects of repeated kappa-opioid receptor agonist U-50488 treatment and subsequent termination on intracranial self-stimulation in male and female rats.

    abstract::Repeated drug administration results in sensitization, tolerance, or no change in subsequent drug-induced alterations of motivated behaviors, such as intracranial self-stimulation (ICSS). For example, repeated mu-opioid agonist administration results in increased expression of mu agonist-induced facilitation of ICSS. ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000287

    authors: Faunce KE,Banks ML

    更新日期:2020-02-01 00:00:00

  • Mild stress increases attentional bias in social drinkers who drink to cope: a replication and extension.

    abstract::The authors investigated the effects of a laboratory stressor task on rapid initial orienting and delayed disengagement aspects of attentional bias for alcohol-related cues in social drinkers (N = 58). Participants were randomly allocated to receive a stress induction or control manipulation before completing a visual...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0017090

    authors: Field M,Quigley M

    更新日期:2009-10-01 00:00:00

  • Allocating under the influence: Effects of alcohol intoxication and social identification on in-group favoritism.

    abstract::The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000186

    authors: Zhou J,Heim D,Monk R,Levy A,Pollard P

    更新日期:2018-06-01 00:00:00

  • Social facilitation of d-amphetamine self-administration in rats.

    abstract::The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0024682

    authors: Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

    更新日期:2011-12-01 00:00:00

  • Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence.

    abstract::In the United States, the Food and Drug Administration (FDA) has initiated a public dialogue about reducing the nicotine content of cigarettes. A reduced-nicotine standard could increase withdrawal symptoms among current smokers. We examined the impact of switching smokers to cigarettes that varied in nicotine content...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1037/pha0000179

    authors: Dermody SS,McClernon FJ,Benowitz N,Luo X,Tidey JW,Smith TT,Vandrey R,Hatsukami D,Donny EC

    更新日期:2018-06-01 00:00:00

  • Craving is associated with smoking relapse: findings from three prospective studies.

    abstract::In a combined sample of more than 2600 smokers, immediate postcessation craving is shown to be prospectively associated with smokers' ability to maintain abstinence. Relapse is strikingly rapid among those reporting high levels of craving following cessation. More than 32% of those with high craving scores relapsed wi...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.5.2.137

    authors: Killen JD,Fortmann SP

    更新日期:1997-05-01 00:00:00

  • Addiction to prescription opioids: characteristics of the emerging epidemic and treatment with buprenorphine.

    abstract::Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,评审

    doi:10.1037/a0013637

    authors: Mendelson J,Flower K,Pletcher MJ,Galloway GP

    更新日期:2008-10-01 00:00:00