The effects of cadmium contamination on the discriminative stimulus properties of cocaine and related drugs.

abstract：:This study shows that a moderate dose of alcohol (0.62 g/kg) can impair cognitive processes controlling behavioral inhibition and flexibility (i.e., inhibiting one response and making a different one). Two groups of male social drinkers (n = 8) received alcohol or a placebo and performed two change tasks that required...

journal_title：Experimental and clinical psychopharmacology

authors： Easdon CM,Vogel-Sprott M

更新日期：2000-08-01 00:00:00

abstract：:The consumption of caffeine has become a growing concern, partially because of the withdrawal properties of the drug. The current study examined personality correlates of caffeine consumption and dependence in 60 university students. Self-report and behavioral measures of sensation seeking, impulsivity, and risk takin...

journal_title：Experimental and clinical psychopharmacology

authors： Jones HA,Lejuez CW

更新日期：2005-08-01 00:00:00

abstract：:Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...

journal_title：Experimental and clinical psychopharmacology

authors： Gruber SA,Silveri MM,Dahlgren MK,Yurgelun-Todd D

更新日期：2011-06-01 00:00:00

abstract：:The authors investigated the effects of a laboratory stressor task on rapid initial orienting and delayed disengagement aspects of attentional bias for alcohol-related cues in social drinkers (N = 58). Participants were randomly allocated to receive a stress induction or control manipulation before completing a visual...

journal_title：Experimental and clinical psychopharmacology

authors： Field M,Quigley M

更新日期：2009-10-01 00:00:00

abstract：:The authors tested the hypothesis that the effects of nicotine on affect are moderated by the presence or absence of emotionally positive and negative stimuli and by attentional choice to avoid attending to emotionally negative stimuli. Thirty-two habitual smokers were assigned to tasks allowing attentional freedom to...

journal_title：Experimental and clinical psychopharmacology

authors： Gilbert DG,Riise H,Dillon A,Huber J,Rabinovich NE,Sugai C

更新日期：2008-02-01 00:00:00

abstract：:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a struct...

journal_title：Experimental and clinical psychopharmacology

authors： Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

更新日期：2002-11-01 00:00:00

abstract：:Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...

journal_title：Experimental and clinical psychopharmacology

authors： Mendelson J,Flower K,Pletcher MJ,Galloway GP

更新日期：2008-10-01 00:00:00

abstract：:The consumption of alcohol mixed with energy drinks (AmED) has become a popular and controversial practice among young people. Increased rates of impaired driving and injuries have been associated with AmED consumption. The purpose of this study was to examine if the consumption of AmED alters cognitive processing and...

journal_title：Experimental and clinical psychopharmacology

authors： Marczinski CA,Fillmore MT,Henges AL,Ramsey MA,Young CR

更新日期：2012-04-01 00:00:00

abstract：:The present, subjective value of a reinforcer typically decreases as a function of the delay to its receipt, a phenomenon termed delay discounting. Delay discounting, which is assumed to reflect impulsivity, is hypothesized to play an important role in drug abuse. The present study examined delay discounting of cocain...

journal_title：Experimental and clinical psychopharmacology

authors： Woolverton WL,Myerson J,Green L

更新日期：2007-06-01 00:00:00

abstract：:Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Tapscott BE,Krishnan-Sarin S

更新日期：2016-04-01 00:00:00

abstract：:Delay discounting, reflected in the tendency to prefer immediate rewards over delayed rewards, is associated with most forms of problematic substance use. When assessed multiple times to examine within-individual changes, for example, following acute drug administration or an intervention, shifts in delay discounting ...

journal_title：Experimental and clinical psychopharmacology

authors： Kuang J,Milhorn H,Stuppy-Sullivan A,Jung S,Yi R

更新日期：2018-10-01 00:00:00

abstract：:Estrogen increases and progesterone decreases the acquisition and reinstatement of cocaine-seeking behavior in female rats. Here estrogen and progesterone were studied for their effects on the escalation of cocaine self-administration in female rats. The rats received ovariectomy (OVX) or sham (SH) surgery and were tr...

journal_title：Experimental and clinical psychopharmacology

authors： Larson EB,Anker JJ,Gliddon LA,Fons KS,Carroll ME

更新日期：2007-10-01 00:00:00

abstract：:A series of experiments in rats explored the possibility that D3/D2 dopamine receptors are involved in behaviors that might be related to compulsion. A series of D3/D2 agonists and antagonists were shown to elicit yawning (D3-receptor mediated) and its inhibition (D2-receptor mediated). In rats with histories of cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Woods JH

更新日期：2008-12-01 00:00:00

abstract：:The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...

journal_title：Experimental and clinical psychopharmacology

authors： Boucart M,Waucquier N,Michael GA,Libersa C

更新日期：2007-02-01 00:00:00

abstract：:Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...

journal_title：Experimental and clinical psychopharmacology

authors： Lawyer SR,Schoepflin F,Green R,Jenks C

更新日期：2011-08-01 00:00:00

abstract：:In an elegant series of experiments, F. Leri and J. Stewart (2002) report that exposure to heroin increases subsequent reinstatement responding if the animal has access to the drug lever during the lapse and if responding on the lever results in the presentation of conditioned cues. It is interesting that exposure to ...

journal_title：Experimental and clinical psychopharmacology

authors： Goeders NE

更新日期：2002-11-01 00:00:00

abstract：:Some abused drugs have been reported to alter performance on naturalistic tasks such as driving and also on laboratory tasks. The performance effects of several drug classes were examined using a repeated measures design. Eight volunteers were administered 2 doses of ethanol, marijuana, amphetamine, hydromorphone, pen...

journal_title：Experimental and clinical psychopharmacology

authors： Pickworth WB,Rohrer MS,Fant RV

更新日期：1997-08-01 00:00:00

abstract：:Smoking-related cues tend to produce urges and cardiac responses in smokers. This reactivity has been assumed to reflect prior classical conditioning. However, little direct evidence exists supporting the notion that environmental cues can be classically conditioned to cigarette smoking. In this study, 8 smokers recei...

journal_title：Experimental and clinical psychopharmacology

authors： Lazev AB,Herzog TA,Brandon TH

更新日期：1999-02-01 00:00:00

abstract：:Drug abuse and impulsive choice are related in humans. In female rats, impulsive choice predicted the rate of acquisition of IV cocaine self-administration. The objectives of the present experiments were to: (a) compare impulsive choice in males and females, (b) extend previous research on impulsive choice and acquisi...

journal_title：Experimental and clinical psychopharmacology

authors： Perry JL,Nelson SE,Carroll ME

更新日期：2008-04-01 00:00:00

abstract：:Heavy smokers (N = 408, smoking more than 25 cigarettes/day) were randomized to receive high-dose (25 mg) or standard-dose (15 mg) nicotine patch therapy delivered during the daytime only (16 hr) for a period of 6 weeks. Treatment effects of each dose were similar. The percentages of participants not smoking at 2-, 6-...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Davis L,Strausberg L,Varady A

更新日期：1999-08-01 00:00:00

abstract：:Alcohol and cannabis couse is highly prevalent and associated with various negative consequences. The likelihood of same day couse is high, especially among men, however, underlying mechanisms to their couse and its sex-dependent nature remain poorly understood. This study aims to elucidate the effects of controlled a...

journal_title：Experimental and clinical psychopharmacology

authors： Venegas A,Meredith LR,Green R,Cooper ZD,Ray LA

更新日期：2020-07-13 00:00:00

abstract：:Six features of the report are commented on. First, the Therapeutic Workplace intervention described in the report represents a creative and promising new approach to drug abuse treatment. Second, to the author's knowledge, it represents the first intervention that has been shown in a randomized clinical trial to sign...

journal_title：Experimental and clinical psychopharmacology

authors： Higgins ST

更新日期：2001-02-01 00:00:00

abstract：:Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...

journal_title：Experimental and clinical psychopharmacology

authors： Kleykamp BA,Griffiths RR,Mintzer MZ

更新日期：2010-02-01 00:00:00

abstract：:Smoking rates are higher in U.S. soldiers than civilians, with combat-experienced soldiers particularly at risk for heavy smoking (≥20 cigarettes/day). While heavy smoking is correlated with mental health symptoms in civilian samples, the extent to which these symptoms, background variables, and unit climate (self-rep...

journal_title：Experimental and clinical psychopharmacology

authors： Lopez AA,Toblin RL,Riviere LA,Lee JD,Adler AB

更新日期：2018-06-01 00:00:00

abstract：:Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases...

journal_title：Experimental and clinical psychopharmacology

authors： Chang HY,Tseng PT,Stubbs B,Chu CS,Li DJ,Fornaro M,Carvalho A,Solmi M,Veronese N,Vieta E,Chen TY,Chen YW,Lin PY,Chow PC

更新日期：2017-10-01 00:00:00

abstract：:Risky choice is the tendency to choose a large, uncertain reward over a small, certain reward, and is typically measured with probability discounting, in which the probability of obtaining the large reinforcer decreases across blocks of trials. One caveat to traditional procedures is that independent schedules are use...

journal_title：Experimental and clinical psychopharmacology

authors： Yates JR,Prior NA,Chitwood MR,Day HA,Heidel JR,Hopkins SE,Muncie BT,Paradella-Bradley TA,Sestito AP,Vecchiola AN,Wells EE

更新日期：2020-04-01 00:00:00

abstract：:Despite considerable health risks due to lower levels of estrogen production and the compounding antiestrogenic effects of nicotine, postmenopausal females continue to smoke. These females face significant barriers to cessation, including negative affect, weight concerns, and menopausal symptom severity. The current p...

journal_title：Experimental and clinical psychopharmacology

authors： Peltier MR,Roys MR,Waters AF,Vinci C,Waldo KM,Stewart SA,Toups RC,Jones L,Copeland AL

更新日期：2018-04-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with complex genetic inheritance. Findings suggest a role for brain-derived neurotrophic factor (BDNF) in OCD, but reports are limited. Here we studied the association of BDNF polymorphisms rs6265 and rs2883187 with OCD and its clinical charact...

journal_title：Experimental and clinical psychopharmacology

authors： Abdolhosseinzadeh S,Alizadeh N,Shams J,Asadi S,Ahmadiani A

更新日期：2020-04-01 00:00:00

abstract：:The nonmedical use of prescription drugs is a widely recognized public health issue, and young adults are particularly vulnerable to their use. Behavioral economic drug purchase tasks capture an individual's strength of desire and motivation for a particular drug. We examined young adult prescription drug purchase and...

journal_title：Experimental and clinical psychopharmacology

authors： Pickover AM,Messina BG,Correia CJ,Garza KB,Murphy JG

更新日期：2016-02-01 00:00:00

abstract：:Drug abuse and obesity are serious public health problems. Dopamine plays a central role in mediating the reinforcing effects of drugs and food. Prolonged use of drugs is known to alter the function and/or sensitivity of many neurotransmitter systems, including dopamine; however, the impact of consuming foods high in ...

journal_title：Experimental and clinical psychopharmacology

authors： Collins GT,Chen Y,Tschumi C,Rush EL,Mensah A,Koek W,France CP

更新日期：2015-08-01 00:00:00