Effects of acute pramipexole on male rats' preference for gambling-like rewards II.

Abstract:

:Pramipexole (PPX) is a dopamine agonist medication that has been implicated in the development of pathological gambling and other impulse control disorders. Johnson, Madden, Brewer, Pinkston, and Fowler (2011) reported that PPX increased male rats' preference for gambling-like rewards (those arranged according to a variable-ratio schedule) over predictable rewards (those obtained from a fixed-ratio schedule). The present experiment explored the possibility that Johnson et al. underestimated the effects of PPX on gambling-like choices by constraining their rats' daily income. In the present experiment conducted in a closed economy, PPX produced a dose-related increase in choice of the gambling-like alternative. In a control condition, PPX did not disrupt choice, suggesting the increased preference for gambling-like rewards was not because of nonspecific drug effects. Our findings are qualitatively consistent with those of Johnson et al., although the dose-related effect and larger effect size in the current study suggest that the effect of PPX on gambling-like choices is more pronounced when income was not constrained. This finding is consistent with clinical reports suggesting PPX is related to the development of problem gambling in humans.

authors

Johnson PS,Madden GJ,Stein JS

doi

10.1037/a0027117

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

167-72

issue

3

eissn

1064-1297

issn

1936-2293

pii

2012-02450-001

journal_volume

20

pub_type

杂志文章
  • Patterns of opioid and cocaine co-use: a descriptive study in a Canadian sample of untreated opioid-dependent individuals.

    abstract::This study examined prevalence and patterns of co-use of opioids and cocaine in regular users of illicit opioids (N = 729) recruited from 5 Canadian cities. Fifty-seven percent (n = 417) reported having used both opioids and cocaine in the month and week preceding the interview; of these, 73% (n = 304) were able to id...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.13.4.303

    authors: Leri F,Stewart J,Fischer B,Jürgen R,Marsh DC,Brissette S,Bruneau J,El-Guebaly N,Noël L,Tyndall MW,Wild TC

    更新日期:2005-11-01 00:00:00

  • Scripted imagery manipulations and smoking cue reactivity in a clinical sample of self-quitters.

    abstract::The affectively valenced scripts used by S. Tiffany (1990) suggest that different scripts produce relatively equivalent levels of cue reactivity, although it is unclear if these laboratory findings generalize to clinical samples. In this study, cessation-motivated smokers were tested 7 days before they tried to quit s...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.6.2.179

    authors: Shadel WG,Niaura R,Abrams DB,Goldstein MG,Rohsenow DJ,Sirota AD,Monti PM

    更新日期:1998-05-01 00:00:00

  • Role of progesterone in nicotine addiction: evidence from initiation to relapse.

    abstract::Nicotine addiction continues to be the main cause of preventable death in developed countries. Women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. While the mechanism of gender differences in nicotine addiction is not yet clear, evidence suggests that ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,评审

    doi:10.1037/a0021265

    authors: Lynch WJ,Sofuoglu M

    更新日期:2010-12-01 00:00:00

  • Nicotine reduces the frequency of anger reports in smokers and nonsmokers with high but not low hostility: an ambulatory study.

    abstract::Two studies were conducted to determine the anger-attenuating effects of nicotine as a function of trait hostility. The 1st study examined the effects of nicotine on diary ratings of anger during a 24-hr period in a natural setting in 30 smokers and 30 nonsmokers. Participants took part in 2 monitoring sessions involv...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1037//1064-1297.7.4.454

    authors: Jamner LD,Shapiro D,Jarvik ME

    更新日期:1999-11-01 00:00:00

  • Stress-related increases in risk taking and attentional failures predict earlier relapse to smoking in young adults: A pilot investigation.

    abstract::Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000066

    authors: Schepis TS,Tapscott BE,Krishnan-Sarin S

    更新日期:2016-04-01 00:00:00

  • Is self-efficacy for smoking abstinence a cause of, or a reflection on, smoking behavior change?

    abstract::Social learning theory considers self-efficacy as a causal factor in behavior change. However, in line with behavioral theory, recent clinical research suggests self-efficacy ratings may reflect, rather than cause, behavior change. To test these two disparate views, self-efficacy was related to actual smoking abstinen...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0025482

    authors: Perkins KA,Parzynski C,Mercincavage M,Conklin CA,Fonte CA

    更新日期:2012-02-01 00:00:00

  • Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence.

    abstract::In the United States, the Food and Drug Administration (FDA) has initiated a public dialogue about reducing the nicotine content of cigarettes. A reduced-nicotine standard could increase withdrawal symptoms among current smokers. We examined the impact of switching smokers to cigarettes that varied in nicotine content...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1037/pha0000179

    authors: Dermody SS,McClernon FJ,Benowitz N,Luo X,Tidey JW,Smith TT,Vandrey R,Hatsukami D,Donny EC

    更新日期:2018-06-01 00:00:00

  • Allocating under the influence: Effects of alcohol intoxication and social identification on in-group favoritism.

    abstract::The "social lubrication" function of alcohol during interpersonal interactions is well documented. However, less is known about the effects of alcohol consumption on group-level behavior. Empirical findings from social psychological literature suggest that individuals tend to favor those who are considered as members ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000186

    authors: Zhou J,Heim D,Monk R,Levy A,Pollard P

    更新日期:2018-06-01 00:00:00

  • Stimulus compounding enhances conditioned suppression produced by cocaine-paired stimuli.

    abstract::When 2 stimuli that occasion cocaine self-administration are presented in compound, their ability to increase cocaine-reinforced operant responding is substantially enhanced. The goal of the present experiment was to determine whether stimulus compounding could produce analogous enhancements of a classically condition...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.8.1.6

    authors: Panlilio LV,Weiss SJ,Schindler CW

    更新日期:2000-02-01 00:00:00

  • Temporal discounting in heroin-dependent patients: no sign effect, weaker magnitude effect, and the relationship with inhibitory control.

    abstract::Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0029657

    authors: Cheng J,Lu Y,Han X,González-Vallejo C,Sui N

    更新日期:2012-10-01 00:00:00

  • Intoxicated behavioral disinhibition and the heart rate response to alcohol.

    abstract::This study examined the association between the heart rate (HR) response to alcohol intoxication, which is thought to reflect sensitivity to alcohol-induced reward and alcohol-induced behavioral disinhibition. High- and low-HR responders to alcohol participated in a go/no-go task, under sober and intoxicated condition...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.14.3.377

    authors: Assaad JM,Pihl RO,Séguin JR,Nagin DS,Vitaro F,Tremblay RE

    更新日期:2006-08-01 00:00:00

  • Aggressiveness, family history of alcoholism, and the heart rate response to alcohol intoxication.

    abstract::Some sons of male alcoholics (SOMAs) are characterized by an increased heart rate (HR) response to alcohol intoxication, which is thought to reflect increased sensitivity to alcohol-induced reward. Such a response has also been related to increased physical aggression. However, the confounding effect of aggression in ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.11.2.158

    authors: Assaad JM,Pihl RO,Séguin JR,Nagin D,Vitaro F,Carbonneau R,Tremblay RE

    更新日期:2003-05-01 00:00:00

  • Adolescents who experienced negative alcohol-related consequences are willing to experience these consequences again in the future.

    abstract::Alcohol use and risky single occasion drinking are common among adolescents and are associated with a higher risk of various negative social, physical, academic, or sexual consequences. Studies have shown that among college students, willingness to experience negative consequences is associated with a higher likelihoo...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000184

    authors: Wicki M,Mallett KA,Delgrande Jordan M,Reavy R,Turrisi R,Archimi A,Kuntsche E

    更新日期:2018-04-01 00:00:00

  • A preliminary investigation of rapid smoking as a lapse-responsive treatment for tobacco dependence.

    abstract::Lapses within the first 2 weeks of a smoking cessation attempt are strongly associated with a return to regular smoking (S. L. Kenford et al., 1994). Unfortunately, little is known about how to prevent an initial lapse from progressing to a full relapse, and presently there are no validated lapse-responsive therapeuti...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1037/1064-1297.14.4.429

    authors: Juliano LM,Houtsmuller EJ,Stitzer ML

    更新日期:2006-11-01 00:00:00

  • Risk factors in the relationship between gender and crack/cocaine.

    abstract::Female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than on any other drug. Additionally, female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than their male counterparts, despite no cons...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.15.2.165

    authors: Lejuez CW,Bornovalova MA,Reynolds EK,Daughters SB,Curtin JJ

    更新日期:2007-04-01 00:00:00

  • Why so impulsive? White matter alterations are associated with impulsivity in chronic marijuana smokers.

    abstract::Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0023034

    authors: Gruber SA,Silveri MM,Dahlgren MK,Yurgelun-Todd D

    更新日期:2011-06-01 00:00:00

  • The efficacy and tolerability of paliperidone in mania of bipolar disorder: A preliminary meta-analysis.

    abstract::Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. This is the first meta-analysis to evaluate the efficacy, safety, and tolerability of paliperidone for the treatment of BD. We performed a systematic search of the literature using major electronic databases...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1037/pha0000148

    authors: Chang HY,Tseng PT,Stubbs B,Chu CS,Li DJ,Fornaro M,Carvalho A,Solmi M,Veronese N,Vieta E,Chen TY,Chen YW,Lin PY,Chow PC

    更新日期:2017-10-01 00:00:00

  • Placebo cigarettes in smoking research.

    abstract::This review outlines the development and use of placebo cigarettes in smoking research. Research on effects of smoking has been disadvantaged by the lack of an adequate placebo condition. Recently, tobacco-based denicotinized cigarettes have been used in smoking research to distinguish effects of smoking due to the de...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章,评审

    doi:10.1037//1064-1297.8.3.326

    authors: Robinson ML,Houtsmuller EJ,Moolchan ET,Pickworth WB

    更新日期:2000-08-01 00:00:00

  • Alcohol and behavioral control: impaired response inhibition and flexibility in social drinkers.

    abstract::This study shows that a moderate dose of alcohol (0.62 g/kg) can impair cognitive processes controlling behavioral inhibition and flexibility (i.e., inhibiting one response and making a different one). Two groups of male social drinkers (n = 8) received alcohol or a placebo and performed two change tasks that required...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.8.3.387

    authors: Easdon CM,Vogel-Sprott M

    更新日期:2000-08-01 00:00:00

  • Effects of estrogen and progesterone on the escalation of cocaine self-administration in female rats during extended access.

    abstract::Estrogen increases and progesterone decreases the acquisition and reinstatement of cocaine-seeking behavior in female rats. Here estrogen and progesterone were studied for their effects on the escalation of cocaine self-administration in female rats. The rats received ovariectomy (OVX) or sham (SH) surgery and were tr...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.15.5.461

    authors: Larson EB,Anker JJ,Gliddon LA,Fons KS,Carroll ME

    更新日期:2007-10-01 00:00:00

  • The subjective and reinforcing effects of visual and olfactory stimuli in alcohol drinking.

    abstract::Nonpharmacological cues associated with drug intake may influence subjective and reinforcing effects of those drugs. Social drinkers (N = 80) participated in 2 sessions in which they rated and then consumed ad lib their preferred beer (with participants blind to brand). Visual and olfactory stimuli were obscured durin...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.11.4.269

    authors: Perkins KA,Ciccocioppo M,Jacobs L,Doyle T,Caggiula A

    更新日期:2003-11-01 00:00:00

  • Personality correlates of caffeine dependence: the role of sensation seeking, impulsivity, and risk taking.

    abstract::The consumption of caffeine has become a growing concern, partially because of the withdrawal properties of the drug. The current study examined personality correlates of caffeine consumption and dependence in 60 university students. Self-report and behavioral measures of sensation seeking, impulsivity, and risk takin...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.13.3.259

    authors: Jones HA,Lejuez CW

    更新日期:2005-08-01 00:00:00

  • Characterizing nicotine withdrawal in pregnant cigarette smokers.

    abstract::Maternal smoking is a leading preventable cause of poor pregnancy outcomes and infant morbidity and mortality. Whereas pregnancy has been thought of as a "window of opportunity" when women are more motivated to change health behaviors such as smoking, only 20% of pregnant women quit smoking upon learning they are preg...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/1064-1297.14.2.165

    authors: Heil SH,Higgins ST,Mongeon JA,Badger GJ,Bernstein IM

    更新日期:2006-05-01 00:00:00

  • Drug-induced reinstatement to heroin and cocaine seeking: a rodent model of relapse in polydrug use.

    abstract::The authors investigated several features of polydrug use in rats. Heroin and cocaine were self-administered following responses on different levers, with only 1 drug and 1 lever available on alternate days of training. Four doses of each drug (heroin: 25, 50, 100, and 200 microg/kg/infusion; cocaine: 0.25, 0.5, 1, an...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.9.3.297

    authors: Leri F,Stewart J

    更新日期:2001-08-01 00:00:00

  • Treatment of heroin-dependent poly-drug abusers with contingency management and buprenorphine maintenance.

    abstract::This study targeted poly-drug (cocaine plus heroin) abstinence among buprenorphine-maintained participants with a 12-week voucher-based reinforcement therapy (VBRT) phase versus a yoked control condition. Baseline levels of cocaine and heroin use were significant predictors of treatment outcome, regardless of treatmen...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.8.2.176

    authors: Downey KK,Helmus TC,Schuster CR

    更新日期:2000-05-01 00:00:00

  • Modeling the effects of combined behavioral and pharmacological treatment on cigarette smoking: behavioral-economic analyses.

    abstract::Effects of different response requirements, response-independent cigarette puffs, and an alternative nondrug reinforcer on cigarette smoking were assessed in 2 experiments. The response requirement to obtain 2 puffs on a cigarette was manipulated while various numbers of response-independent puffs were provided (0, 6,...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1037//1064-1297.5.4.334

    authors: Bickel WK,Madden GJ,DeGrandpre RJ

    更新日期:1997-11-01 00:00:00

  • Opposing effects of dopamine D1- and D2-like agonists on intracranial self-stimulation in male rats.

    abstract::Dopamine acts through dopamine Type I receptors (comprising D1 and D5 subtypes) and dopamine Type II receptors (comprising D2, D3, and D4 subtypes). Intracranial self-stimulation (ICSS) is 1 experimental procedure that can be used to evaluate abuse-related effects of drugs targeting dopamine receptors. This study eval...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/pha0000067

    authors: Lazenka MF,Legakis LP,Negus SS

    更新日期:2016-06-01 00:00:00

  • Craving is associated with smoking relapse: findings from three prospective studies.

    abstract::In a combined sample of more than 2600 smokers, immediate postcessation craving is shown to be prospectively associated with smokers' ability to maintain abstinence. Relapse is strikingly rapid among those reporting high levels of craving following cessation. More than 32% of those with high craving scores relapsed wi...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.5.2.137

    authors: Killen JD,Fortmann SP

    更新日期:1997-05-01 00:00:00

  • Methamphetamine impairs sexual motivation but not sexual performance in male Japanese quail.

    abstract::The present study investigated the effects of chronic pre-exposure to methamphetamine on sexual motivation and performance in male Japanese quail. Quail were pre-exposed to methamphetamine (1.0 or 3.0 mg/kg ip) or saline (ip) once daily for 10 days and locomotor activity was measured. After a 10 day washout period, se...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037/a0014505

    authors: Bolin BL,Akins CK

    更新日期:2009-02-01 00:00:00

  • The observing-response procedure: a novel method to study drug-associated conditioned reinforcement.

    abstract::In this experiment, the observing-response procedure was adapted for use with drug self-administration. Rats' responding for oral ethanol was sometimes reinforced on a random-ratio schedule, whereas at other times it had no effect (i.e., extinction). Behavior producing stimuli associated with the otherwise unsignaled ...

    journal_title:Experimental and clinical psychopharmacology

    pub_type: 杂志文章

    doi:10.1037//1064-1297.10.1.3

    authors: Shahan TA

    更新日期:2002-02-01 00:00:00