Low efficacy opioids: implications for sex differences in opioid antinociception.

abstract：:This study shows that a moderate dose of alcohol (0.62 g/kg) can impair cognitive processes controlling behavioral inhibition and flexibility (i.e., inhibiting one response and making a different one). Two groups of male social drinkers (n = 8) received alcohol or a placebo and performed two change tasks that required...

journal_title：Experimental and clinical psychopharmacology

authors： Easdon CM,Vogel-Sprott M

更新日期：2000-08-01 00:00:00

abstract：:Smoking-related cues tend to produce urges and cardiac responses in smokers. This reactivity has been assumed to reflect prior classical conditioning. However, little direct evidence exists supporting the notion that environmental cues can be classically conditioned to cigarette smoking. In this study, 8 smokers recei...

journal_title：Experimental and clinical psychopharmacology

authors： Lazev AB,Herzog TA,Brandon TH

更新日期：1999-02-01 00:00:00

abstract：:Previous field research has shown that individuals consumed more alcohol and at a faster rate in environments paired with loud music. Theoretically, this effect has been linked to approach/avoidance accounts of how music influences arousal and mood, but no work has tested this experimentally. In the present study, fem...

journal_title：Experimental and clinical psychopharmacology

authors： Stafford LD,Dodd H

更新日期：2013-10-01 00:00:00

abstract：:The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

journal_title：Experimental and clinical psychopharmacology

authors： Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

更新日期：2011-12-01 00:00:00

abstract：:Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,Fillmore MT,Milich R

更新日期：2012-04-01 00:00:00

abstract：:In the United States, marijuana is the most commonly used illicit drug. Its prevalence is growing, particularly among young adults. Behavioral economic indices of the relative reinforcing efficacy (RRE) of substances have been used to examine the appeal of licit (e.g., alcohol) and illicit (e.g., heroin) drugs. The pr...

journal_title：Experimental and clinical psychopharmacology

authors： Collins RL,Vincent PC,Yu J,Liu L,Epstein LH

更新日期：2014-06-01 00:00:00

abstract：:Heavy drinking among college students is a public health concern in part due to the accessibility of alcohol and promotions such as "happy hours," which discount the price of alcohol. In addition, consuming alcohol at unregulated off-campus parties may result in greater alcohol consumption, higher blood alcohol concen...

journal_title：Experimental and clinical psychopharmacology

authors： Morrell MN,Reed DD,Martinetti MP

更新日期：2020-03-19 00:00:00

abstract：:Some abused drugs have been reported to alter performance on naturalistic tasks such as driving and also on laboratory tasks. The performance effects of several drug classes were examined using a repeated measures design. Eight volunteers were administered 2 doses of ethanol, marijuana, amphetamine, hydromorphone, pen...

journal_title：Experimental and clinical psychopharmacology

authors： Pickworth WB,Rohrer MS,Fant RV

更新日期：1997-08-01 00:00:00

abstract：:Cocaine dependence constitutes a significant public health concern. This randomized, double-blind, placebo-controlled trial tested a novel approach to reducing cocaine use among cocaine-dependent individuals with d-cycloserine, a drug known to enhance learning and some learning-based therapies. Urine samples and cocai...

journal_title：Experimental and clinical psychopharmacology

authors： Johnson MW,Bruner NR,Johnson PS,Silverman K,Berry MS

更新日期：2020-04-01 00:00:00

abstract：:The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effe...

journal_title：Experimental and clinical psychopharmacology

authors： Baldwin RL,Chelonis JJ,Flake RA,Edwards MC,Feild CR,Meaux JB,Paule MG

更新日期：2004-02-01 00:00:00

abstract：:Dopamine acts through dopamine Type I receptors (comprising D1 and D5 subtypes) and dopamine Type II receptors (comprising D2, D3, and D4 subtypes). Intracranial self-stimulation (ICSS) is 1 experimental procedure that can be used to evaluate abuse-related effects of drugs targeting dopamine receptors. This study eval...

journal_title：Experimental and clinical psychopharmacology

authors： Lazenka MF,Legakis LP,Negus SS

更新日期：2016-06-01 00:00:00

abstract：:Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...

journal_title：Experimental and clinical psychopharmacology

authors： Kleykamp BA,Griffiths RR,Mintzer MZ

更新日期：2010-02-01 00:00:00

abstract：:Habitual substance use is associated with attentional bias for stimuli related to the use. The current study tested whether individuals' substance use can be predicted from their attentional bias for concern-related and substance-related stimuli. Participants (N = 71; 54% male) were selected among university students ...

journal_title：Experimental and clinical psychopharmacology

authors： Fadardi JS,Ziaee S,Shamloo ZS

更新日期：2009-12-01 00:00:00

abstract：:Nonpharmacological cues associated with drug intake may influence subjective and reinforcing effects of those drugs. Social drinkers (N = 80) participated in 2 sessions in which they rated and then consumed ad lib their preferred beer (with participants blind to brand). Visual and olfactory stimuli were obscured durin...

journal_title：Experimental and clinical psychopharmacology

authors： Perkins KA,Ciccocioppo M,Jacobs L,Doyle T,Caggiula A

更新日期：2003-11-01 00:00:00

abstract：:Two groups of male Japanese quail (Coturnix japonica) were trained [corrected] to discriminate cocaine from saline in a conditioned approach procedure maintained by sexual reinforcement. For 1 group, cocaine (10 mg/kg ip) was administered prior to a conditioned stimulus (CS) that predicted copulation; saline followed ...

journal_title：Experimental and clinical psychopharmacology

authors： Troisi JR 2nd,Akins C

更新日期：2004-11-01 00:00:00

abstract：:A burgeoning literature supports a link between alcohol use and panic-spectrum problems (e.g., panic attacks, disorder) among adolescents, but the direction of influence has yet to be properly examined. From a theoretical perspective, panic-spectrum problems may increase risk for problematic drinking via affect regula...

journal_title：Experimental and clinical psychopharmacology

authors： Blumenthal H,Cloutier RM,Zamboanga BL,Bunaciu L,Knapp AA

更新日期：2015-10-01 00:00:00

abstract：:Drug cue reactivity is theoretically and clinically important. The modified Stroop task has been widely used to assess attention capture by drug cues (attentional bias). Attentional bias to drug cues is assumed to reflect the incentive value of those cues, but this has not been directly tested. The authors examined wh...

journal_title：Experimental and clinical psychopharmacology

authors： Waters AJ,Carter BL,Robinson JD,Wetter DW,Lam CY,Kerst W,Cinciripini PM

更新日期：2009-08-01 00:00:00

abstract：:While smokers are known to find smoking-related stimuli motivationally salient, the extent to which former smokers do so is largely unknown. In this study, we collected event-related potential (ERP) data from former and never smokers and compared them to a sample of current smokers interested in quitting who completed...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson JD,Versace F,Engelmann JM,Cui Y,Slapin A,Oum R,Cinciripini PM

更新日期：2015-02-01 00:00:00

abstract：:In Experiment 1, the effect of repeated injections of 2.5, 5.0, or 10.0 mg/kg of chlordiazepoxide (CDP) on food intake and body weight was studied in rats on an activity anorexia (AA) regimen. For several days before CDP testing began, rats lived in activity wheels and had one 60-min meal per day. During CDP testing, ...

journal_title：Experimental and clinical psychopharmacology

authors： Lett BT,Grant VL,Koh MT,Parsons JF

更新日期：1998-11-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with complex genetic inheritance. Findings suggest a role for brain-derived neurotrophic factor (BDNF) in OCD, but reports are limited. Here we studied the association of BDNF polymorphisms rs6265 and rs2883187 with OCD and its clinical charact...

journal_title：Experimental and clinical psychopharmacology

authors： Abdolhosseinzadeh S,Alizadeh N,Shams J,Asadi S,Ahmadiani A

更新日期：2020-04-01 00:00:00

abstract：:This review outlines the development and use of placebo cigarettes in smoking research. Research on effects of smoking has been disadvantaged by the lack of an adequate placebo condition. Recently, tobacco-based denicotinized cigarettes have been used in smoking research to distinguish effects of smoking due to the de...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson ML,Houtsmuller EJ,Moolchan ET,Pickworth WB

更新日期：2000-08-01 00:00:00

abstract：:Cigarette smoking is highly prevalent among patients who are being treated for opioid-dependence, yet there have been limited scientific efforts to promote smoking cessation in this population. Contingency management (CM) is a behavioral treatment that provides monetary incentives contingent upon biochemical evidence ...

journal_title：Experimental and clinical psychopharmacology

authors： Dunn KE,Saulsgiver KA,Sigmon SC

更新日期：2011-02-01 00:00:00

abstract：:Despite depressive symptoms being very common among patients seeking treatment for cocaine dependence, few studies have examined the effects of depressive symptoms on cocaine outpatient treatment outcomes, and there is even less research in the context of Contingency Management (CM). The purpose of this study was to a...

journal_title：Experimental and clinical psychopharmacology

authors： García-Fernández G,Secades-Villa R,García-Rodríguez O,Peña-Suárez E,Sánchez-Hervás E

更新日期：2013-12-01 00:00:00

abstract：:Lapses within the first 2 weeks of a smoking cessation attempt are strongly associated with a return to regular smoking (S. L. Kenford et al., 1994). Unfortunately, little is known about how to prevent an initial lapse from progressing to a full relapse, and presently there are no validated lapse-responsive therapeuti...

journal_title：Experimental and clinical psychopharmacology

authors： Juliano LM,Houtsmuller EJ,Stitzer ML

更新日期：2006-11-01 00:00:00

abstract：:Children's alcohol expectancies shift in late childhood/early adolescence in ways thought to lead to increased risk for adolescent alcohol use. The precise nature of this shift and the maturational processes that may influence it remain to be clarified. To these ends, we compared expectancy endorsement by grade across...

journal_title：Experimental and clinical psychopharmacology

authors： Bekman NM,Goldman MS,Worley MJ,Anderson KG

更新日期：2011-12-01 00:00:00

abstract：:Prevalence of heavy alcohol use remain high, and daily marijuana use is at an all-time high in young adults. As perceptions of drug effects may guide risky decision making, understanding subjective feelings for alcohol and marijuana use is critical. Existing laboratory-based and diary metrics (0-100 rating of "how dru...

journal_title：Experimental and clinical psychopharmacology

authors： Linden-Carmichael AN,Masters LD,Lanza ST

更新日期：2020-12-01 00:00:00

abstract：:Delay discounting, reflected in the tendency to prefer immediate rewards over delayed rewards, is associated with most forms of problematic substance use. When assessed multiple times to examine within-individual changes, for example, following acute drug administration or an intervention, shifts in delay discounting ...

journal_title：Experimental and clinical psychopharmacology

authors： Kuang J,Milhorn H,Stuppy-Sullivan A,Jung S,Yi R

更新日期：2018-10-01 00:00:00

abstract：:The effect of benzodiazepines on attention has been the object of few investigations. Studies using the spatial cueing paradigm (Posner's paradigm) have reported inconsistent results, which are likely due to methodological and/or dose differences but suggest impaired disengagement of attention from the cue to the targ...

journal_title：Experimental and clinical psychopharmacology

authors： Boucart M,Waucquier N,Michael GA,Libersa C

更新日期：2007-02-01 00:00:00

abstract：:Maternal smoking is a leading preventable cause of poor pregnancy outcomes and infant morbidity and mortality. Whereas pregnancy has been thought of as a "window of opportunity" when women are more motivated to change health behaviors such as smoking, only 20% of pregnant women quit smoking upon learning they are preg...

journal_title：Experimental and clinical psychopharmacology

authors： Heil SH,Higgins ST,Mongeon JA,Badger GJ,Bernstein IM

更新日期：2006-05-01 00:00:00

abstract：:Research examining the role of pharmacological therapy in the treatment of children and adolescents with clinical disorders is growing. Clinical disorders that present with comorbid aggression can add a challenge to treatment. Child and adolescent neuropsychiatric disorders associated with aggression include attention...

journal_title：Experimental and clinical psychopharmacology

authors： Nevels RM,Dehon EE,Alexander K,Gontkovsky ST

更新日期：2010-04-01 00:00:00