Stimulus compounding enhances conditioned suppression produced by cocaine-paired stimuli.

abstract：:Adolescent brains are particularly susceptible to the rewarding properties of risky decisions in social contexts. Individual differences in genetic influences on dopamine transmission moderate neural outcome processing of risky decisions and may exert pronounced effects on adolescent risk-taking behavior (RTB) and cor...

journal_title：Experimental and clinical psychopharmacology

authors： Webber TA,Soder HE,Potts GF,Park JY,Bornovalova MA

更新日期：2017-02-01 00:00:00

abstract：:Substantial evidence links greater impulsivity and stress exposure to poorer smoking cessation outcomes. Results from adolescents also indicate that stress-related change in risk taking can impede cessation attempts. We investigated the effects of stress-related change in impulsivity, risk taking, attention and nicoti...

journal_title：Experimental and clinical psychopharmacology

authors： Schepis TS,Tapscott BE,Krishnan-Sarin S

更新日期：2016-04-01 00:00:00

abstract：:This report describes a novel procedure for computer-controlled drug-dose determination for IV drug self-administration studies. By modifying the duration of each infusion of a single concentration of a drug solution, five or more unit doses (mg/kg/inj) can be dispensed from the same syringe. The advantages of this pr...

journal_title：Experimental and clinical psychopharmacology

authors： Fivel PA

更新日期：2011-04-01 00:00:00

abstract：:Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...

journal_title：Experimental and clinical psychopharmacology

authors： Cheng J,Lu Y,Han X,González-Vallejo C,Sui N

更新日期：2012-10-01 00:00:00

abstract：:Sprague-Dawley (Rattus norvegicus) rats were trained in a drug discrimination task using the state-dependent interoceptive stimulus attributes of cocaine's delayed or rebound effects (CDE) versus "normal" basal homeostasis. Rats were injected with either 32 mg/kg cocaine or equivalent volumes of saline (SAL), subcutan...

journal_title：Experimental and clinical psychopharmacology

authors： Gauvin DV,Vanecek SA,Baird TJ,Briscoe RJ,Vallett M,Carl KL,Wasielewski JA,Holloway FA

更新日期：1998-08-01 00:00:00

abstract：:Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether delay discounting changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects who completed discounting assessments at ba...

journal_title：Experimental and clinical psychopharmacology

authors： Landes RD,Christensen DR,Bickel WK

更新日期：2012-08-01 00:00:00

abstract：:This study analyzed whether a contingency management (CM) for shaping cessation period implemented prior to an abstinence-only period (CMS) improves outcomes relative to CM that reinforces only a fixed abstinence criteria (CMA) among treatment-seeking patients in a community setting. A total of 110 patients were rando...

journal_title：Experimental and clinical psychopharmacology

authors： Secades-Villa R,López-Núñez C,Weidberg S,González-Roz A,Alonso-Pérez F

更新日期：2019-12-01 00:00:00

abstract：:Alcohol-specific attentional biases (AttB) and approach biases (AppB) are postulated to play a role in alcohol use disorders but their association with drinking in young adults remains unknown. A subsample of young adults with risky alcohol use (N = 296) enrolled in a randomized trial, testing different text message i...

journal_title：Experimental and clinical psychopharmacology

authors： Suffoletto B,Field M,Chung T

更新日期：2020-12-01 00:00:00

abstract：:This study examined the relation of the Five-Factor Model (FFM) of personality to symptoms of alcohol and marijuana abuse before and after controlling for symptoms of antisocial personality disorder (APD) and internalizing psychopathology. The 481 participants completed a well-validated measure of the FFM and a struct...

journal_title：Experimental and clinical psychopharmacology

authors： Flory K,Lynam D,Milich R,Leukefeld C,Clayton R

更新日期：2002-11-01 00:00:00

abstract：:Two groups of male Japanese quail (Coturnix japonica) were trained [corrected] to discriminate cocaine from saline in a conditioned approach procedure maintained by sexual reinforcement. For 1 group, cocaine (10 mg/kg ip) was administered prior to a conditioned stimulus (CS) that predicted copulation; saline followed ...

journal_title：Experimental and clinical psychopharmacology

authors： Troisi JR 2nd,Akins C

更新日期：2004-11-01 00:00:00

abstract：:The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...

journal_title：Experimental and clinical psychopharmacology

authors： Gipson CD,Yates JR,Beckmann JS,Marusich JA,Zentall TR,Bardo MT

更新日期：2011-12-01 00:00:00

abstract：:Repeated drug administration results in sensitization, tolerance, or no change in subsequent drug-induced alterations of motivated behaviors, such as intracranial self-stimulation (ICSS). For example, repeated mu-opioid agonist administration results in increased expression of mu agonist-induced facilitation of ICSS. ...

journal_title：Experimental and clinical psychopharmacology

authors： Faunce KE,Banks ML

更新日期：2020-02-01 00:00:00

abstract：:The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differe...

journal_title：Experimental and clinical psychopharmacology

authors： Jamner LD,Girdler SS,Shapiro D,Jarvik ME

更新日期：1998-02-01 00:00:00

abstract：:Estrogen increases and progesterone decreases the acquisition and reinstatement of cocaine-seeking behavior in female rats. Here estrogen and progesterone were studied for their effects on the escalation of cocaine self-administration in female rats. The rats received ovariectomy (OVX) or sham (SH) surgery and were tr...

journal_title：Experimental and clinical psychopharmacology

authors： Larson EB,Anker JJ,Gliddon LA,Fons KS,Carroll ME

更新日期：2007-10-01 00:00:00

abstract：:Methylphenidate (MPH) is one of the most widely prescribed drugs for treating attention-deficit hyperactivity disorder. Previous research suggested that MPH is a reinforcer for rats, but not all of the manipulations to show that lever pressing is controlled by the contingency to obtain MPH have been examined. In Exper...

journal_title：Experimental and clinical psychopharmacology

authors： Marusich JA,Beckmann JS,Gipson CD,Bardo MT

更新日期：2010-06-01 00:00:00

abstract：:Pramipexole (PPX) is a dopamine agonist medication that has been implicated in the development of pathological gambling and other impulse control disorders. Johnson, Madden, Brewer, Pinkston, and Fowler (2011) reported that PPX increased male rats' preference for gambling-like rewards (those arranged according to a va...

journal_title：Experimental and clinical psychopharmacology

authors： Johnson PS,Madden GJ,Stein JS

更新日期：2012-06-01 00:00:00

abstract：:While smokers are known to find smoking-related stimuli motivationally salient, the extent to which former smokers do so is largely unknown. In this study, we collected event-related potential (ERP) data from former and never smokers and compared them to a sample of current smokers interested in quitting who completed...

journal_title：Experimental and clinical psychopharmacology

authors： Robinson JD,Versace F,Engelmann JM,Cui Y,Slapin A,Oum R,Cinciripini PM

更新日期：2015-02-01 00:00:00

abstract：:Some sons of male alcoholics (SOMAs) are characterized by an increased heart rate (HR) response to alcohol intoxication, which is thought to reflect increased sensitivity to alcohol-induced reward. Such a response has also been related to increased physical aggression. However, the confounding effect of aggression in ...

journal_title：Experimental and clinical psychopharmacology

authors： Assaad JM,Pihl RO,Séguin JR,Nagin D,Vitaro F,Carbonneau R,Tremblay RE

更新日期：2003-05-01 00:00:00

abstract：:There are important individual differences in acute subjective responses to alcohol, which have often been assessed using self-report measures. There is also evidence of meaningful between-persons variation in alcohol's disinhibiting effects on behavior, such that some individuals become more impaired on tasks of inhi...

journal_title：Experimental and clinical psychopharmacology

authors： Quinn PD,Fromme K

更新日期：2016-04-01 00:00:00

abstract：:Habitual substance use is associated with attentional bias for stimuli related to the use. The current study tested whether individuals' substance use can be predicted from their attentional bias for concern-related and substance-related stimuli. Participants (N = 71; 54% male) were selected among university students ...

journal_title：Experimental and clinical psychopharmacology

authors： Fadardi JS,Ziaee S,Shamloo ZS

更新日期：2009-12-01 00:00:00

abstract：:It is becoming increasingly evident that the sex of an organism is a critical determinant of responsiveness to opioid analgesics. However, the factors that determine the magnitude and direction of sex differences in opioid antinociception have not been fully elucidated. One factor that has received attention is the re...

journal_title：Experimental and clinical psychopharmacology

authors： Barrett AC

更新日期：2006-02-01 00:00:00

abstract：:In community-based alcoholism and drug abuse treatment programs, the vast majority of interventions are delivered in a group therapy context. In turn, treatment providers and funding agencies have called for more research on interventions delivered in groups in an effort to make the emerging empirical literature on th...

journal_title：Experimental and clinical psychopharmacology

authors： Morgan-Lopez AA,Fals-Stewart W

更新日期：2006-05-01 00:00:00

abstract：:Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...

journal_title：Experimental and clinical psychopharmacology

authors： Roberts W,Fillmore MT,Milich R

更新日期：2012-04-01 00:00:00

abstract：:The present study explores the relation among 4 personality traits associated with impulsive behavior and alcohol abuse. Personality traits were measured using the 4 subscales of the UPPS Impulsive Behavior Scale (UPPS; S. P. Whiteside & D. R. Lynam, 2001). The UPPS and measures of psychopathology were administered to...

journal_title：Experimental and clinical psychopharmacology

authors： Whiteside SP,Lynam DR

更新日期：2003-08-01 00:00:00

abstract：:Using data from 4 smoking cessation trials conducted from 1988 to 2000, the authors investigated whether men are more successful than women in quitting smoking. Odds ratios indicated that the abstinence rates were not significantly different for men and women. Thus, there may be little value to diverting research fund...

journal_title：Experimental and clinical psychopharmacology

authors： Killen JD,Fortmann SP,Varady A,Kraemer HC

更新日期：2002-08-01 00:00:00

abstract：:Substance use disorders and pathological gambling share similarities in terms of diagnostic criteria, epidemiology, and clinical course. However, relatively few studies have evaluated the efficacy of treatments for gambling disorders. As interest in pathological gambling grows, adaptation of effective treatments from ...

journal_title：Experimental and clinical psychopharmacology

authors： Petry NM

更新日期：2002-08-01 00:00:00

abstract：:There has been a dramatic rise in the consumption of glucose energy drinks (e.g., Amp, Monster, and Red Bull) in the past decade, particularly among high school and college students. However, little laboratory research has examined the acute objective and subjective effects of energy drinks. The purpose of this study ...

journal_title：Experimental and clinical psychopharmacology

authors： Howard MA,Marczinski CA

更新日期：2010-12-01 00:00:00

abstract：:Nicotine addiction continues to be the main cause of preventable death in developed countries. Women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. While the mechanism of gender differences in nicotine addiction is not yet clear, evidence suggests that ...

journal_title：Experimental and clinical psychopharmacology

authors： Lynch WJ,Sofuoglu M

更新日期：2010-12-01 00:00:00

abstract：:The authors investigated the effects of a laboratory stressor task on rapid initial orienting and delayed disengagement aspects of attentional bias for alcohol-related cues in social drinkers (N = 58). Participants were randomly allocated to receive a stress induction or control manipulation before completing a visual...

journal_title：Experimental and clinical psychopharmacology

authors： Field M,Quigley M

更新日期：2009-10-01 00:00:00

abstract：:Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...

journal_title：Experimental and clinical psychopharmacology

authors： Lawyer SR,Schoepflin F,Green R,Jenks C

更新日期：2011-08-01 00:00:00