Getting back to basics: commentary on McSweeney, Murphy, and Kowal (2005).

Abstract:

:The review article "Regulation of Drug Taking by Sensitization and Habituation" by F. K. McSweeney, E. S. Murphy, and B. P. Kowal introduces 2 basic principles of behavior, sensitization and habituation, into a comprehensive model for studying drug intake and drug addiction. A key assumption of the model is that the reinforcing effectiveness of drugs sensitize and/or habituate; however, issues with the measurement of reinforcing effectiveness should be carefully considered. In addition, a multidisciplinary approach might broaden this model and increase its power. Other approaches include, but are not limited to, pharmacokinetic-pharmacodynamic modeling and in vivo measures of brain activity.

authors

Rowlett JK

doi

10.1037/1064-1297.13.3.187

keywords:

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

187-9; discussion 194-9

issue

3

eissn

1064-1297

issn

1936-2293

pii

2005-10634-003

journal_volume

13

pub_type

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