Abstract:
:NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regulation of these responses by the killer cell inhibitory (KIR) receptors.
journal_name
Immunol Revjournal_title
Immunological reviewsauthors
Lanier LL,Corliss B,Phillips JHdoi
10.1111/j.1600-065x.1997.tb00947.xsubject
Has Abstractpub_date
1997-02-01 00:00:00pages
145-54eissn
0105-2896issn
1600-065Xjournal_volume
155pub_type
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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更新日期:1985-10-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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更新日期:2019-11-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章
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更新日期:2006-12-01 00:00:00
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更新日期:2018-07-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:2016-07-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:1998-06-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
doi:10.1111/j.0105-2896.2005.00325.x
更新日期:2005-12-01 00:00:00
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更新日期:2017-03-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
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更新日期:2013-09-01 00:00:00
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更新日期:2008-06-01 00:00:00
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更新日期:2011-09-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:2005-06-01 00:00:00
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journal_title:Immunological reviews
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abstract::With increasing evidence that complement activation significantly contributes to the pathogenesis of a large number of inflammatory diseases, strategies that interfere with its deleterious action have become a major focus in pharmacological research. Endogenous soluble complement inhibitors (C1 inhibitor, recombinant ...
journal_title:Immunological reviews
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更新日期:2001-04-01 00:00:00
abstract::Solid organ transplantation is a vital therapy for end stage diseases. Decades of research have established that components of the adaptive immune system are critical for transplant rejection, but the role of the innate immune system in organ transplantation is just emerging. Accumulating evidence indicates that the i...
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abstract::Multiple myeloma (MM) is a tumor of long-lived bone marrow plasma cells (PCs). Nearly 40% of MM tumors have immunoglobulin H (IgH) translocations involving four recurrent chromosomal loci (oncogenes): 11q13 (cyclin D1), 6p21 (cyclin D3), 4p16 (MMSET and FGFR3), and 16q23 (c-maf). Other MM tumors have Ig translocations...
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更新日期:2003-08-01 00:00:00