Analysis of perchloric-acid-soluble Mycobacterium bovis bacille bilié de Calmette-Guérin antigen.

abstract：BACKGROUND:Asthma is a common co-morbidity of allergic rhinitis (AR). The prevalence of these two allergic diseases has increased in China and has been shown to cluster in families independently. This study evaluated the association between maternal AR (presenting with or without asthma) and the allergic conditions in ...

journal_title：International archives of allergy and immunology

authors： Wang QP,Wu KM,Li ZQ,Xue F,Chen W,Ji H,Wang BL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Asthma is a major health problem worldwide, and the morbidity and mortality caused by asthma are on the rise. Corticosteroid therapies for asthma treatment frequently induce many side effects. Therefore, the development of new medicines that have both high efficacy and fewer side effects has been a scientifi...

journal_title：International archives of allergy and immunology

authors： Lim YJ,Na HS,Yun YS,Choi IS,Oh JS,Rhee JH,Cho BH,Lee HC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The high-affinity IgE receptor, FcepsilonRI, is unresponsive on mast cells and basophils from people in several populations through an unknown mechanism. Similarly, FcepsilonRI-positive basophils from 'nonreleasers' are IgE-unresponsive and are deficient in the tyrosine kinase Syk. OBJECTIVE:To test the hyp...

journal_title：International archives of allergy and immunology

authors： Kepley CL

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:House dust mite (HDM)-sensitive allergic rhinitis is a perennial rhinitis with persistent nasal inflammation. Currently, there are no reliable parameters to monitor the severity of perennial allergic rhinitis. The purpose of this study was to evaluate correlations between clinical and laboratory parameters i...

journal_title：International archives of allergy and immunology

authors： Klaewsongkram J,Ruxrungtham K,Wannakrairot P,Ruangvejvorachai P,Phanupak P

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:We showed previously that treatment with an agonistic anti-4-1BB Ab during the induction phase of murine experimental allergic conjunctivitis (EC) suppresses the development of this model disease. It was reported that 4-1BB promotes the expansion of regulatory T cells. Here we asked whether the suppression o...

journal_title：International archives of allergy and immunology

authors： Sumi T,Ishida W,Mittler RS,Yagita H,Taguchi O,Fukushima A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin (HA) of influenza viruses is one of the major targets of the humoral response. The role of serum antibody to HA in the protection against infection has been demonstrated by long-standing observation. In previous studies, we suggested that an epitope vaccine might be a new strategy against t...

journal_title：International archives of allergy and immunology

authors： Lu Y,Ding J,Liu W,Chen YH

更新日期：2002-03-01 00:00:00

abstract：:A quantitative determination of the inflammatory mediators was performed and correlated with complaints and the measurement of the inflammatory cells in nasal secretions of 18 seasonal allergic rhinitis patients (group 1) outside the pollen season and 40 symptomatic patients (group 2) with seasonal allergic rhinitis d...

journal_title：International archives of allergy and immunology

authors： Wang D,Clement P,Smitz J,De Waele M,Derde MP

更新日期：1995-03-01 00:00:00

abstract：:Accumulation and activation of eosinophils in tissue are critical events in the allergic inflammatory response and adhesion molecules play important roles in this process. We previously demonstrated that human eosinophils expressed a nuclear receptor, peroxisome proliferator-activated receptor gamma (PPARgamma), and t...

journal_title：International archives of allergy and immunology

authors： Hirasawa H,Chiba T,Ueki S,Kamada Y,Ito W,Takeda M,Fujita M,Kato H,Kayaba H,Chihara J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The implementation of allergen immunotherapy (AIT) requires extensive knowledge of allergen distribution in the region to identify high-risk regions for AIT utilization. However, the geographical distribution patterns of the major Dermatophagoides allergens in China remain unclear despite the increasing prev...

journal_title：International archives of allergy and immunology

authors： Chen ZG,Li YT,Wang WH,Tan KS,Zheng R,Yang LF,Guan WJ,Hong HY,Yang QT

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Ultra-rush regimens for administering sublingual immunotherapy to patients with allergies are becoming more widespread. We aimed to assess treatment safety for patients with allergic rhinitis with or without asthma caused by Dermatophagoides house dust mites. METHODS:This observational study at 5 Spanish ce...

journal_title：International archives of allergy and immunology

authors： Roger A,Justicia JL,Navarro LÁ,Eseverri JL,Ferrès J,Malet A,Alvà V

更新日期：2011-01-01 00:00:00

abstract：:We evaluated whether c-myc and ras P-21 oncogene expression could identify familial polyposis coli/Gardner's syndrome patients at risk for colon cancer. Monoclonal antibodies recognizing c-myc and ras P-21 proteins were used in immunohistochemistry to stain 26 paraffin-embedded tissue specimens collected over 12 years...

journal_title：International archives of allergy and immunology

authors： Yuwono M,Rossi TM,Fisher JE,Tjota A

更新日期：1996-09-01 00:00:00

abstract：:Hypersensitivity pneumonitis remains an important industrial disease in mushroom workers. It has a significant morbidity, and early diagnosis and removal from exposure to the antigen are critically important in its management. Recently, several new allergens have been described, particularly those from mushroom specie...

journal_title：International archives of allergy and immunology

authors： Moore JE,Convery RP,Millar BC,Rao JR,Elborn JS

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:A number of different molecules are known to be involved in the signal pathway to release histamine from mast cells, among which arachidonic acid (AA) is one of the key mediators. On the other hand, we found that the application of compound 48/80, a typical histamine liberator, generated superoxide in mast c...

journal_title：International archives of allergy and immunology

authors： Sakaguchi M,Fukuishi N,Teramoto K,Miyazaki M,Huh NH,Namba M,Akagi M

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:In vivo, all blood vessels are lined by a single layer of flattened noncycling endothelial cells. We tested the hypothesis that the maintenance of such a quiescent endothelial monolayer depends on homotypic contacts between not yet defined growth-inhibitory molecules located at interendothelial junctions. M...

journal_title：International archives of allergy and immunology

authors： Halama T,Staffler G,Hoch S,Stockinger H,Wolff K,Petzelbauer P

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Nitrosative and acid stress play an important role in the pathogenesis of asthma. The aim of this study was to evaluate whether, in asthmatics, a link exists between the concentrations of nitrite/nitrate, ammonia and pH values in exhaled breath condensate (EBC) and asthma severity, lung function, exhaled nit...

journal_title：International archives of allergy and immunology

authors： Tomasiak-Lozowska MM,Zietkowski Z,Przeslaw K,Tomasiak M,Skiepko R,Bodzenta-Lukaszyk A

更新日期：2012-01-01 00:00:00

abstract：:The low responsiveness of contact sensitivity (CS) in sensitized and challenged mice was induced by using hapten-amino acid derivatives. Subcutaneous injection of trinitrophenyl (TNP)-lysine or oxazolone-glycine inhibited ear swelling responses in mice that received rechallenge. The inhibitory effect was long-lasting ...

journal_title：International archives of allergy and immunology

authors： Satoh T,Yokozeki H,Katayama I,Nishioka K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:alpha-Melanocyte-stimulating hormone (alpha-MSH) is a neuropeptide that controls melanogenesis in pigmentary cells. In addition, its potent immunomodulatory activity has been recently described in cutaneous inflammatory disorders. However the mechanism of such pollen allergies remains to be elucidated. The p...

journal_title：International archives of allergy and immunology

authors： Hiramoto K,Hashimoto M,Orita K,Jikumaru M,Sato EF,Inoue M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35%, autoimmune urticaria (AIU) at 25% and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. METHODS:Differences in clinical and laboratory parameters among AIU, PU and CIU groups were...

journal_title：International archives of allergy and immunology

authors： Irinyi B,Széles G,Gyimesi E,Tumpek J,Herédi E,Dimitrios G,Adány R,Hunyadi J,Szegedi A

更新日期：2007-01-01 00:00:00

abstract：:Bronchial asthma, characterized by eosinophilic inflammation in airways, may involve Th2-type cytokines such as interleukin-5 (IL-5). IL-12, a newly established cytokine, induces IFN-gamma production, which may have a regulatory effect on the production of Th2-type cytokines. We examined the effects of IL-12 on the pr...

journal_title：International archives of allergy and immunology

authors： Okano Y,Nakamura Y,Sano T,Azuma M,Sone S

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:DNA immunization and protein immunization with CpG motifs as adjuvants represent promising approaches in allergen-specific immunotherapy. OBJECTIVE:We investigated the effect of coinjection or prepriming with CpG-ODN on Th2-type responses induced by gene gun and protein immunization. METHODS:BALB/c mice we...

journal_title：International archives of allergy and immunology

authors： Hochreiter R,Hartl A,Freund J,Valenta R,Ferreira F,Thalhamer J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:While searching for antigliadin and anticasein antibodies in sera from coeliac patients we investigated more than 20 persons suffering from this enteropathy. In some of sera, we registered antibodies against gliadin and in parallel the appearance of anticasein antibodies. A high percentage of glutamic acid h...

journal_title：International archives of allergy and immunology

authors： Paranos S,Nikolic G

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:A subset of drug-intolerant patients show a marked propensity to react to several chemically unrelated antibacterial drugs. This condition is termed multiple drug allergy syndrome (MDAS). The pathogenesis of MDAS is still unclear. A possible mechanism is that a nonspecific patient-related factor leading to d...

journal_title：International archives of allergy and immunology

authors： Asero R,Tedeschi A,Lorini M,Caldironi G,Barocci F

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:It is important to understand that allergic rhinitis, whether seasonal or perennial, may be difficult to distinguish clinically from the nonallergic forms of rhinitis. OBJECTIVE:This study aimed to investigate the presence of local allergic rhinitis (LAR) in children who have allergic rhinitis symptoms in t...

journal_title：International archives of allergy and immunology

authors： Duman H,Bostanci I,Ozmen S,Dogru M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The fractional concentration of exhaled nitric oxide (FeNO) is a surrogate biomarker for Th2-dependent bronchial inflammation. The present study investigated whether FeNO may characterize allergic rhinitis (AR) patients. METHODS:A total of 553 AR patients (497 males, mean age 28.8 years) were evaluated. Tho...

journal_title：International archives of allergy and immunology

authors： Ciprandi G,Gallo F,Ricciardolo FL,Cirillo I

更新日期：2017-01-01 00:00:00

abstract：:IL-13 is a relatively novel cytokine produced by activated T cells. IL-13 inhibits the production of proinflammatory cytokines and chemokines by activated monocytes, induces B cell proliferation and differentiation, including IgE production, and the expression of certain adhesion molecules on endothelial cells. All th...

journal_title：International archives of allergy and immunology

authors： de Vries JE,Zurawski G

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Epinephrine autoinjector (EAI) is prescribed to prevent a fatal outcome in the case of a repeated anaphylactic reactions. We wanted to determine how adult patients who received their first prescription as part of an urgent treatment of an anaphylactic reaction or at their family physician were instructed on ...

journal_title：International archives of allergy and immunology

authors： Kadivec S,Košnik M

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:Mercury causes in mouse strains of the H-2s haplotype an autoimmune syndrome with antibodies to the nucleolar protein fibrillarin and systemic immune complex (IC) deposits. Other strains, like BALB/C (H-2d), develop only IC deposits, and most strains are resistant. However, mercury activates the murine immun...

journal_title：International archives of allergy and immunology

authors： Johansson U,Hansson-Georgiadis H,Hultman P

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demograp...

journal_title：International archives of allergy and immunology

authors： Ferriani MP,Silva MF,Pereira RM,Terreri MT,Saad Magalhães C,Bonfá E,Pastorino AC,Carolina Dos Santos M,Appenzeller S,Ferriani VP,Len CA,Sallum AM,Libório J,Monteiro de Castro TC,Silva CA

更新日期：2015-01-01 00:00:00

abstract：:The role of CD8+ T cells in the regulation of IgE was investigated by in vivo CD8+ T-cell depletion. Following intraperitoneal immunization with ovalbumin (OVA), OVA-specific T cell responses were first detected in the draining lymph nodes (LN) and subsequently in the spleen. In vitro depletion of LN CD8+ cells reduce...

journal_title：International archives of allergy and immunology

authors： Holmes BJ,MacAry PA,Kemeny DM

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Autoimmune disorders are considered to be associated with a Th1 immune response while allergic diseases with a Th2 response. We carried out a study to determine whether there is an inverse relationship between allergic diseases in IgE-sensitized children or positive skin-prick test reactions to allergens and...

journal_title：International archives of allergy and immunology

authors： Caffarelli C,Cavagni G,Pierdomenico R,Chiari G,Spattini A,Vanelli M

更新日期：2004-08-01 00:00:00