Rhodnius prolixus: salivary antihemostatic components decrease with Trypanosoma rangeli infection.

Abstract:

:Feeding behavior and some antihemostatic properties of the saliva of Rhodnius prolixus infected with Trypanosoma rangeli were studied and compared with those of uninfected controls. Insects with salivary gland infection pierced host skin more often and drew less blood and at a lower rate than controls when feeding on a rabbit. None of these differences was observed when feeding was performed through a membrane feeder. Salivary gland homogenates from infected insects, at 30 days after feeding/infection, had a significantly lower amount of total protein/salivary gland pair and less anticoagulant activity than controls. Also, infected salivary glands exhibited significantly reduced apyrase activities and reactive nitrogen groups when compared to controls. It is concluded that salivary infection of T. rangeli impairs the ability of the vector to locate blood vessels by affecting salivary antihemostatic properties, thus enhancing the possibility of intradermal inoculation of parasites into the mammalian host.

journal_name

Exp Parasitol

authors

Garcia ES,Mello CB,Azambuja P,Ribeiro JM

doi

10.1006/expr.1994.1030

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

287-93

issue

3

eissn

0014-4894

issn

1090-2449

pii

S0014-4894(84)71030-7

journal_volume

78

pub_type

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