An improved method to obtain antigen-excreting Toxocara canis larvae.

abstract：:We have identified congenic mouse strains that differ dramatically in resistance to infection with the murine malaria parasite Plasmodium yoelii 17X. After infection, BALB/c mice develop severe anemia and a high degree of parasitemia which sometimes results in death. The mtv-7 congenic strain BALB.D2.mlsa, however, de...

journal_title：Experimental parasitology

authors： Swardson CJ,Wassom DL,Avery AC

更新日期：1997-06-01 00:00:00

abstract：:S(2) complex has been reported to have a direct antileishmanial effect. The possibility that the direct antileishmanial effect may be due to inhibition of key enzymes involved in glucose metabolism and/ or enzymes associated with virulence was investigated. Cell pellets were prepared from cultures of both axenic amast...

journal_title：Experimental parasitology

authors： Al-Mulla Hummadi YM,Al-Bashir NM,Najim RA

更新日期：2006-02-01 00:00:00

abstract：:In the present study, we examined the effect of the histone deacetylase (HDAC) inhibitors trichostatin A (TSA), valproic acid (VA) and sodium-butyrate on the metamorphosis of larvae of the human blood-fluke Schistosoma mansoni from the free-swimming miracidia into the intramolluskal sporocyst. We show that HDAC inhibi...

journal_title：Experimental parasitology

authors： Azzi A,Cosseau C,Grunau C

更新日期：2009-03-01 00:00:00

abstract：:Trypanosoma cruzi is the ethiological agent for Chagas disease in Latin America. This study aimed to test the trypanocidal effect of licarin A and burchellin isolated from plants in northeastern Brazil. These neolignans were tested on T. cruzi and on peritoneal macrophages, to evaluate drug toxicity. Epimastigote grow...

journal_title：Experimental parasitology

authors： Cabral MM,Barbosa-Filho JM,Maia GL,Chaves MC,Braga MV,De Souza W,Soares RO

更新日期：2010-03-01 00:00:00

abstract：:Protective immunity against a Plasmodium falciparum blood infection can be passively transferred by antibodies in humans and in the primate experimental malaria model Saimiri sciureus. We report here the emergence of a novel virulent parasite population after such passive transfer of hyperimmune serum in splenectomize...

journal_title：Experimental parasitology

authors： Morales-Betoulle ME,de la Salmonière YO,Zwetyenga J,Le Scanf C,Jouin H,Michel JC

更新日期：1998-09-01 00:00:00

abstract：:Aedes albopictus mosquito is an opportunistic blood feeder and has a broad host range. The feeding behavior and habits of this mosquito are liable to increase the transmission potential of arboviruses. The survival and fecundity in A. albopictus fed on different hosts and post-blood meal provision of sugar were invest...

journal_title：Experimental parasitology

authors： Xue RD,Ali A,Barnard DR

更新日期：2008-06-01 00:00:00

abstract：:By using a sensitive fluorometric method with Val-Leu-Gly-Arg-3-amino-9-ethylcarbazole (VLGR-AEC) as a substrate, two endopeptidase activities were identified in two fractions of Sephacryl S-200 gel filtration from soluble P. berghei and P. chabaudi extracts. Controls with normal mouse erythrocytes, with leukocytes, a...

journal_title：Experimental parasitology

authors： Bernard F,Mayer R,Picard I,Deguercy A,Monsigny M,Schrevel J

更新日期：1987-08-01 00:00:00

abstract：:Human cysticercosis caused by Taenia crassiceps is unusual; however, it is an useful experimental model for cysticercosis studies. Benzimidazole derivatives are important antihelminthic drugs widely used against helminths. A novel compound 6-chloro-5-(1-naphthyloxy) -2-(trifluoromethyl)-1H-benzimidazole (RCB20) is a b...

journal_title：Experimental parasitology

authors： Fraga CM,da Costa TL,de Castro AM,Reynoso-Ducoing O,Ambrosio J,Hernández-Campos A,Castillo R,Vinaud MC

更新日期：2017-01-01 00:00:00

abstract：:The cDNA of a Schistosoma japonicum myophilin-like protein was cloned, sequenced, and expressed in Escherichia coli as a recombined protein (rSj myophilin-like protein), and the protein was purified by affinity chromatography. The deduced amino acid sequences of the Sj myophilin-like protein showed significant homolog...

journal_title：Experimental parasitology

authors： Peng H,Song K,Huang C,Ye S,Song H,Hu W,Han Z,McManus DP,Zhao G,Zhang Q

更新日期：2008-05-01 00:00:00

abstract：:Cytoadherence of Plasmodium falciparum-infected erythrocytes to amelanotic melanoma cells was pH dependent; increased adherence was observed in the pH range of 6.1 to 6.8 and was greatest between pH 6.6 and 6.8 Ca2+ promoted cytoadherence, but at higher concentrations (40-50 mM) than is usually the case for cell-cell ...

journal_title：Experimental parasitology

authors： Crandall I,Smith H,Sherman IW

更新日期：1991-10-01 00:00:00

abstract：:Entomopathogenic nematodes complete their life cycles inside dead insects. The emergence of new infective juveniles from the cadaver has been attributed (but never demonstrated) to food depletion or to the accumulation of metabolites from the breakdown of the host's tissues. Here we give evidence that emergence is tri...

journal_title：Experimental parasitology

authors： San-Blas E,Gowen SR,Pembroke B

更新日期：2008-05-01 00:00:00

abstract：:The schistosomicidal activity of praziquantel (PZQ) is accompanied by a large influx of calcium into the worms, suggesting that this phenomenon could be the source of the observed muscular contraction, surface disruption and eventual death of the parasite. We have incubated live adult schistosomes in a medium containi...

journal_title：Experimental parasitology

authors： Pica-Mattoccia L,Orsini T,Basso A,Festucci A,Liberti P,Guidi A,Marcatto-Maggi AL,Nobre-Santana S,Troiani AR,Cioli D,Valle C

更新日期：2008-07-01 00:00:00

abstract：:Amebiasis contributes to approximately 50 million cases of life-threatening dysentery worldwide. Comparison of the lectins from Entamoeba histolytica (pathogenic) and Entamoeba dispar (nonpathogenic) was undertaken to elucidate the differential roles of this molecule in invasion versus colonization. Surface lectin was...

journal_title：Experimental parasitology

authors： Pillai DR,Kobayashi S,Kain KC

更新日期：2001-12-01 00:00:00

abstract：:Schistosoma mansoni infection in humans and animals induces abnormal neurobehavioral responses following granuloma formation. In mice, granulomas in the liver are observed 8 weeks after infection, while after 15-20 weeks, the presence of eggs and granulomas in the brain has been reported. In this study, outbred CD-1 f...

journal_title：Experimental parasitology

authors： Fiore M,Moroni R,Alleva E,Aloe L

更新日期：1996-06-01 00:00:00

abstract：:Philasterides dicentrarchi is a histophagous scuticociliate infecting Korean olive flounder farms in Jeju Island, South Korea, where it causes significant economic losses. However, the route of entry of these parasites in olive flounder is currently unknown. In the present study, we attempted experimental infection wi...

journal_title：Experimental parasitology

authors： Harikrishnan R,Jin CN,Kim JS,Balasundaram C,Heo MS

更新日期：2012-03-01 00:00:00

abstract：:One difficulty facing post-genomic analyses of schistosomes is the limited data on sites of expression of many gene products expressed by the parasites in their hosts. The potential for use of laser microdissection microscopy as a preparative technique for transcriptional and proteomic profiling is reviewed. This tech...

journal_title：Experimental parasitology

authors： Jones MK,Higgins T,Stenzel DJ,Gobert GN

更新日期：2007-11-01 00:00:00

abstract：:Lipophosphoglycan (LPG) is structurally characterized by a series of phosphoglycan repeat units. Cellular LPG, isolated from promastigotes, has a very similar structure to culture supernatant LPG, but differs in the average number of phosphorylated oligosaccharide repeat units and in glycan composition. Comparison of ...

journal_title：Experimental parasitology

authors： Kavoosi G,Ardestani SK,Kariminia A,Alimohammadian MH

更新日期：2010-02-01 00:00:00

abstract：:Murine malarial parasites have long been characterized by their requirement for either antibody-mediated immunity (AMI) or cell-mediated immunity (CMI) for suppression of acute parasitemia, with Plasmodium yoelii reportedly requiring AMI for suppression and P. chabaudi requiring CMI. To assess this characterization in...

journal_title：Experimental parasitology

authors： van der Heyde HC,Pepper B,Batchelder J,Cigel F,Weidanz WP

更新日期：1997-02-01 00:00:00

abstract：:In this study, a survey was conducted in order to determine the presence and pathogenic potential of free-living amoebae of Acanthamoeba genus in a population of Barbary Ground squirrels in Fuerteventura Island (Canary Islands, Spain) and Morocco. Identification of Acanthamoeba was based on the morphology of cyst and ...

journal_title：Experimental parasitology

authors： Lorenzo-Morales J,López-Darias M,Martínez-Carretero E,Valladares B

更新日期：2007-09-01 00:00:00

abstract：:Typically, antimicrobial peptides (AMPs) are short positive charged peptides serving a key role in innate immunity as well as antimicrobial activity. Discovering novel therapeutic agents is considered as an undeniable demand due to increasing microbial species with antibiotic resistance. In this direction, the unique ...

journal_title：Experimental parasitology

authors： Zahedifard F,Lee H,No JH,Salimi M,Seyed N,Asoodeh A,Rafati S

更新日期：2020-02-01 00:00:00

abstract：:There has been some evidence from several parasite systems that proteinases might have potential as protective antigens against parasitic infection. A cysteine proteinase complex identified in the regurgitant of adult F. hepatica was examined in this context. The thiol-cathepsin-related proteinases of M(r) 28,000 were...

journal_title：Experimental parasitology

authors： Wijffels GL,Salvatore L,Dosen M,Waddington J,Wilson L,Thompson C,Campbell N,Sexton J,Wicker J,Bowen F

更新日期：1994-03-01 00:00:00

abstract：:Infection with Leishmania infantum causes the disease visceral leishmaniasis (VL), which is a serious clinical and veterinary problem. The drugs used to treat canine leishmaniasis (CanL) do not cause complete parasite clearance; they can be toxic, and emerging drug resistance in parasite populations limits their clini...

journal_title：Experimental parasitology

authors： Miret JA,Moreno J,Nieto J,Carter KC,Mullen AB,Ambros L,Rodríguez C,San Andrés MI,González F

更新日期：2021-01-01 00:00:00

abstract：:Trypanosoma cruzi epimastigotes cultured in vitro were disrupted by successive freezing and thawing and subsequent sonication. The total homogenate was fractionated by differential centrifugation to obtain an enriched plasma membrane fraction. The proteins of subcellular parasite fractions were labeled with 131I and t...

journal_title：Experimental parasitology

authors： Calderon RO,de Fabro SP

更新日期：1983-10-01 00:00:00

abstract：:During its parasitic life stages, the marine ectoparasitic copepod Lepeophtheirus salmonis ingests large amounts of host blood, which contains high amounts of iron. Iron is an essential micronutrient, but also toxic in high dosages, and blood-feeding parasites like the salmon louse must thus possess an efficient syste...

journal_title：Experimental parasitology

authors： Tröße C,Kongshaug H,Dondrup M,Nilsen F

更新日期：2015-10-01 00:00:00

abstract：:The presence of the cytoskeleton of Acanthamoeba castellanii was observed by means of cryo-electronmicroscopy and immunofluorescence techniques. This structure is formed largely by fibers and networks of actin located mainly in cytoplasmic locomotion structures as lamellipodia and as well as in various endocytic struc...

journal_title：Experimental parasitology

authors： González-Robles A,Castañón G,Hernández-Ramírez VI,Salazar-Villatoro L,González-Lázaro M,Omaña-Molina M,Talamás-Rohana P,Martínez-Palomo A

更新日期：2008-07-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) constitute a large family of Zn(2+) and Ca(2+) dependent endopeptidases implicated in tissue remodeling and chronic inflammation. MMPs also play key roles in the activation of growth factors, chemokines and cytokines produced by many cell types, including lymphocytes, granulocytes, and...

journal_title：Experimental parasitology

authors： de Pinho RT,da Silva WS,de Castro Côrtes LM,da Silva Vasconcelos Sousa P,de Araujo Soares RO,Alves CR

更新日期：2014-12-01 00:00:00

abstract：:Malaria caused by the protozoan parasite Plasmodium falciparum, is a major health problem of the developing world. In the present study medicinal plants from Eastern Ghats of South India have been extracted with ethyl acetate and assayed for growth inhibition of asexual erythrocytic stages of chloroquine (CQ)-sensitiv...

journal_title：Experimental parasitology

authors： Kaushik NK,Bagavan A,Rahuman AA,Mohanakrishnan D,Kamaraj C,Elango G,Zahir AA,Sahal D

更新日期：2013-05-01 00:00:00

abstract：:Cutaneous lesions elicited in guinea pigs by primary and secondary feeding populations of the argasid tick, Ornithodorus tartakovskyi, were analyzed by light and electron microscopy. Small clusters of basophils appeared at primary bite sites within 24 hr of tick attachment, and by 72 hr constituted approximately 11% o...

journal_title：Experimental parasitology

authors： McLaren DJ,Worms MJ,Brown SJ,Askenase PW

更新日期：1983-10-01 00:00:00

abstract：:Chemotherapy of food-borne trematodes relies on two drugs, praziquantel and tricabendazole, and there is growing interest in finding alternative therapies. Plant oil extracts have long been used in traditional Chinese medicine as sources of bioactive compounds with antiparasitic activity. Species of the genus Echinost...

journal_title：Experimental parasitology

authors： Souza JG,Lopes Torres EJ,Garcia JS,Gomes AP,Rodrigues-Silva R,Maldonado A Jr,Machado-Silva JR

更新日期：2017-03-01 00:00:00

abstract：:In murine Schistosoma mansoni infections, fewer adult worms develop in male than in female mice infected with the same number of cercariae. To evaluate a potential role for testosterone in this phenomenon, testosterone levels were manipulated in groups of CBA/J mice that were then infected and monitored for survival r...

journal_title：Experimental parasitology

authors： Nakazawa M,Fantappie MR,Freeman GL Jr,Eloi-Santos S,Olsen NJ,Kovacs WJ,Secor WE,Colley DG

更新日期：1997-03-01 00:00:00