Abstract：
:Schistosoma mansoni sporocysts originally derived from monomiracidially infected Biomphalaria glabrata snails were serially transplanted into the cephalopedal sinus of anesthetized snails by the microsurgical implantation of fragments of parasitized hepatopancreas and ovotestis. Three to six passages each of five male and five female clones were maintained for as long as 2.0 years. Of the recipient snails which survived surgery, 87% released cercariae, usually beginning 5-7 weeks after surgery. The percentage of snails which released cercariae increased with successive passages. The mean survival time of surgically infected snails after cercarial emergence began was 9.2 +/- 0.5 weeks, nearly the same as that of miracidially infected snails. Longevities of snails infected with male or female clones were similar. Recipient snail size and age did not influence cloning success. Beginning 5 weeks from the onset of cercarial emergence large numbers of cercariae (a mean of 3900/snail from male clones and 1300/snail from females) were obtained during each shedding period. These results clearly demonstrate that the microsurgical transplantation of sporocysts is a practical means of maintaining and expanding populations of genetically homogeneous schistosomes (clones).
journal_name
Exp Parasitoljournal_title
Experimental parasitologyauthors
Cohen LM,Eveland LKdoi
10.1016/0014-4894(84)90056-0subject
Has Abstractpub_date
1984-02-01 00:00:00pages
15-9issue
1eissn
0014-4894issn
1090-2449pii
0014-4894(84)90056-0journal_volume
57pub_type
杂志文章abstract：:Trypanosoma congolense is an important pathogen that wreaks havoc in the livestock industry of the African continent. This study evaluated the in vivo antitrypanosomal activity of geranylacetone and its ameliorative effect on the disease-induced anaemia and organ damages as well as its inhibitory effects against trypa...
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journal_title：Experimental parasitology
pub_type： 杂志文章
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journal_title：Experimental parasitology
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：2015-09-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1006/expr.2001.4622
更新日期：2001-06-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.exppara.2008.04.014
更新日期：2008-09-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2006.01.008
更新日期：2006-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0014-4894(89)90178-1
更新日期：1989-08-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2009.10.011
更新日期：2010-09-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2009.03.004
更新日期：2009-06-01 00:00:00
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journal_title：Experimental parasitology
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更新日期：1992-09-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：1992-03-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1006/expr.1997.4147
更新日期：1997-05-01 00:00:00
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doi：10.1016/j.exppara.2015.09.003
更新日期：2015-12-01 00:00:00
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journal_title：Experimental parasitology
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更新日期：2016-03-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：1986-06-01 00:00:00
abstract：:Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi, which is transmitted by insects of the family Reduviidae. Since conventional treatments with nitroheterocyclic drugs show serious adverse reactions and have questionable...
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2011.12.001
更新日期：2012-02-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：2018-02-01 00:00:00
abstract：:Two strains of mice which share identical H-2 genes but differ in their genetic backgrounds were compared for their ability to resist infection with Trichinella spiralis. The two strains of mice, C3HeB/FeJ and AKR/J, share the H-2k haplotype which is associated with susceptibility to primary infection with T. spiralis...
journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/0014-4894(83)90009-7
更新日期：1983-04-01 00:00:00
