High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone.

abstract：:While long-term effects of temperature treatment in respect of, e.g., gene-expression and cellular function have already been studied in some detail, nothing is known on the physiological responses of lymphocytes during short-term hypothermal shifts. In this report, we characterized the effects of such a stimulation u...

journal_title：FEBS letters

authors： Wurm S,Paar C,Sonnleitner A,Sonnleitner M,Höglinger O,Romanin C,Wechselberger C

更新日期：2004-05-21 00:00:00

abstract：:A role for the cytokines produced by tissue-infiltrated inflammatory cells (mainly T-lymphocytes and mast cells) in the pathophysiology of fibrosis has been suggested by several groups. Among the products of these cells, interleukin-4 (IL-4) might be one of the factors involved in the initiation of the fibrotic proces...

journal_title：FEBS letters

authors： Gillery P,Fertin C,Nicolas JF,Chastang F,Kalis B,Banchereau J,Maquart FX

更新日期：1992-05-18 00:00:00

abstract：:A cDNA clone of about 2300 base pairs was prepared from the human osteosarcoma cell line U-2 OS by hybridization with a 22-mer oligonucleotide complementary to the NH2-terminus of PDGF-A. Restriction and sequence analysis showed that this clone contains the entire coding region for PDGF-A and a long 3'-untranslated re...

journal_title：FEBS letters

authors： Hoppe J,Schumacher L,Eichner W,Weich HA

更新日期：1987-11-02 00:00:00

abstract：:Saccharomyces bayanus var. uvarum investigated here is the species closest to Saccharomyces cerevisiae. Random sequence tags (RSTs) allowed us to identify homologues to 2789 open reading frames (ORFs) in S. cerevisiae, ORFs duplicated in S. uvarum but not in S. cerevisiae, centromeres, tRNAs, homologues of Ty1/2 and T...

journal_title：FEBS letters

authors： Bon E,Neuvéglise C,Casaregola S,Artiguenave F,Wincker P,Aigle M,Durrens P

更新日期：2000-12-22 00:00:00

abstract：:32P-Labelled tRNA was isolated from uninfected and phage phi 149-infected Vibrio cholerae cells. These tRNA preparations were then hybridised with DNA isolated from phage phi 149. Significant hybridisation was observed only with tRNA from phage phi 149-infected cells. This strongly suggests that infection of classical...

journal_title：FEBS letters

authors： Ghosh RK,Guhathakurta I

更新日期：1983-10-03 00:00:00

abstract：:BSP-30K is a major acidic glycoprotein of bovine seminal plasma. It displays heparin-, gelatin-, and phospholipid-binding activities. BSP-30K binds to spermatozoa upon ejaculation and is thought to play a role in sperm capacitation. We have determined its amino acid sequence, disulfide bonds, and 0-glycosylation sites...

journal_title：FEBS letters

authors： Calvete JJ,Mann K,Sanz L,Raida M,Töpfer-Petersen E

更新日期：1996-12-09 00:00:00

abstract：:Casein phosphopeptides beta-CN(1-25)4P and alpha(s1)-CN(59-79)5P, from beta- and alpha(s1)-casein, respectively, both carrying the characteristic 'acidic motif' Ser(P)-Ser(P)-Ser(P)-Glu-Glu, were chemically synthesized and administered to HT-29 cells differentiated in culture, which are a used model of intestinal epit...

journal_title：FEBS letters

authors： Ferraretto A,Gravaghi C,Fiorilli A,Tettamanti G

更新日期：2003-09-11 00:00:00

abstract：:When cultured porcine aortic endothelial cells (ECs) were incubated with porcine big endothelin-1 (bit ET-1(1-39)), there was a time-dependent increase in immunoreactive (IR)-ET in the culture supernatant, in addition to an endogenous IR-ET release fron the cells. Reverse-phase HPLC of the culture supernatant revealed...

journal_title：FEBS letters

authors： Ikegawa R,Matsumura Y,Tsukahara Y,Takaoka M,Morimoto S

更新日期：1991-11-18 00:00:00

abstract：:Rubrivivax gelatinosus is a facultative phototrophic non-sulfur bacterium belonging to the beta subclass of the purple bacteria. A terbutryn-resistant mutant of R. gelatinosus has been isolated and characterized. Increased resistance levels to terbutryn (300-fold), atrazine (6-fold) and o-phenanthroline (3-fold) were ...

journal_title：FEBS letters

authors： Ouchane S,Picaud M,Astier C

更新日期：1995-10-23 00:00:00

abstract：:The article presents the results of the first regular study of Russian populations by sequencing the control region of mitochondrial DNA (mtDNA). The sequenced region is the most variable on mtDNA molecule and is commonly used for population and evolutionary studies. Russians form one of the largest ethnic groups (mor...

journal_title：FEBS letters

authors： Orekhov V,Poltoraus A,Zhivotovsky LA,Spitsyn V,Ivanov P,Yankovsky N

更新日期：1999-02-19 00:00:00

abstract：:Toll-like receptors (TLRs) are crucial components of the innate immune system, coupling pathogen recognition to a cellular response. We used the MAPPIT mammalian two-hybrid technique to investigate protein-protein interactions in the early steps in TLR signalling. A partial TLR-adaptor interaction map was constructed ...

journal_title：FEBS letters

authors： Ulrichts P,Peelman F,Beyaert R,Tavernier J

更新日期：2007-02-20 00:00:00

abstract：:To gain insight into the nuclear organization of the mouse Ig kappa locus and how it may relate to the formation of synapses during recombination, we have studied the kinetics of rearrangement of different V kappa gene families to J kappa gene segments in the pre-B cell line, 103bcl2. Remarkably, V kappa gene families...

journal_title：FEBS letters

authors： Li S,Garrard WT

更新日期：2003-02-11 00:00:00

abstract：:Tumor necrosis factor alpha (TNF-α) is a prototypical proinflammatory cytokine that can elicit strong inflammation in macrophages by activating NF-κB. The underlying epigenetic mechanism is obscure. We show here that megakaryocytic leukemia 1 (MKL1) is an epigenetic mediator of TNF-α-induced proinflammatory transcript...

journal_title：FEBS letters

authors： Song M,Fang F,Dai X,Yu L,Fang M,Xu Y

更新日期：2017-03-01 00:00:00

abstract：:Cytochrome oxidase exhibits phosphorescence from tryptophan in aqueous solution in the absence of oxygen. The lifetime for the resting reduced enzyme suspended in Tween-20 is around 30 ms at pH 8. The lifetime is longest between pH 7 and 8 and decreases with lowering of pH. Oxygen quenches the phosphorescence with a S...

journal_title：FEBS letters

authors： Papp S,King TE,Vanderkooi JM

更新日期：1991-05-20 00:00:00

abstract：:Prostaglandin E2 receptors (EPR), which belong to the family of heterotrimeric G protein-coupled ectoreceptors with seven transmembrane domains, can be classified into four subtypes according to their ligand binding and G protein coupling specificity. Of these, EP3betaR is coupled to Gi, whereas EP4R is coupled to Gs....

journal_title：FEBS letters

authors： Neuschäfer-Rube F,Hänecke K,Püschel GP

更新日期：1997-09-29 00:00:00

abstract：:We report a new method for the detection of ligand-induced receptor internalization by fluorescence ratiometric imaging of pH in endosomes in combination with a recently developed posttranslational labeling system based on the formation of a heterodimeric coiled-coil structure. The N-terminus of the β2-adrenergic rece...

journal_title：FEBS letters

authors： Yano Y,Matsuzaki K

更新日期：2011-07-21 00:00:00

abstract：:We report isolation of a murine gene, NPYR-D, which predicts an intronless novel G protein-coupled receptor of 375 amino acids. Percent identities of NPYR-D to the clone Y1, Y2, rat Y4/PP1 and human Y4/PP1 receptors are 45, 32, 92 and 76, respectively. Southern blots indicate that NPYR-D and human Y4/PP1 receptor gene...

journal_title：FEBS letters

authors： Gregor P,Millham ML,Feng Y,DeCarr LB,McCaleb ML,Cornfield LJ

更新日期：1996-02-26 00:00:00

abstract：:Using a panel of monoclonal antibodies, it has previously been demonstrated that the cytosol of nucleated red cells (trout and turkey) contains a protein similar to arrestin, a soluble protein found so far only in the photosensitive cells and which, by binding to photoexcited rhodopsin, inhibits the phototransduction ...

journal_title：FEBS letters

authors： Scheuring U,Franco M,Fievet B,Guizouarn H,Mirshahi M,Faure JP,Motais R

更新日期：1990-12-10 00:00:00

abstract：:Binding of the thiazolyl peptide antibiotic thiostrepton to the GTPase domain of 23S rRNA involves a few crucial nucleotides, notably A1067 (E. coli). Small RNA transcripts were prepared corresponding to the GTPase domain of the plastid 23S rRNA and the two forms of cytosolic 28S rRNAs found in the human malaria paras...

journal_title：FEBS letters

authors： Clough B,Strath M,Preiser P,Denny P,Wilson IR

更新日期：1997-04-07 00:00:00

abstract：:According to the endosymbiont hypothesis, mitochondria are descended from ancient aerobic bacteria that were engulfed by protoeukaryotic cells. Experiments described here show that a synthetic peptide corresponding to a yeast mitochondrial targeting sequence can be imported into Paracoccus denitrificans, a soil bacter...

journal_title：FEBS letters

authors： Roise D,Maduke M

更新日期：1994-01-03 00:00:00

abstract：:The effect of synthetic cationic lipids on the structure of DNA was studied. The fluorescence enhancement of ethidium bromide on intercalation into DNA was suppressed by the addition of bilayer-forming lipids, but not by micellar ones. Results on the fluorescence depolarization index suggest that ethidium bromide is n...

journal_title：FEBS letters

authors： Akao T,Fukumoto T,Ihara H,Ito A

更新日期：1996-08-05 00:00:00

abstract：:The role of lipids in the interaction of the beta-adrenergic receptor (R) with the regulatory protein (Gs) was investigated. Solubilized preparations of R and of Gs from turkey erythrocytes were delipidated by gel filtration. They were subsequently combined and reconstituted by the addition of various lipids. When rec...

journal_title：FEBS letters

authors： Kirilovsky J,Steiner-Mordoch S,Selinger Z,Schramm M

更新日期：1985-04-08 00:00:00

abstract：:The unfolded protein response (UPR)--the endoplasmic reticulum stress response--is found in various pathologies including ischemia-reperfusion injury (IRI). However, its role during IRI is still unclear. Here, by combining two different bioinformatical methods--a method based on ordinary differential equations (Time S...

journal_title：FEBS letters

authors： Le Pape S,Dimitrova E,Hannaert P,Konovalov A,Volmer R,Ron D,Thuillier R,Hauet T

更新日期：2014-08-25 00:00:00

abstract：:The effect of the three platelet-derived growth factor (PDGF) isoforms AA, AB and BB on the induction of the early growth response genes c-fos, egr-1 and c-myc mRNA in vascular smooth muscle cells from rat was compared with their respective mitogenic potency. The three PDGF isoforms strongly stimulated the induction t...

journal_title：FEBS letters

authors： Sachinidis A,Schulte K,Ko Y,Meyer zu Brickwedde MK,Hoppe V,Hoppe J,Vetter H

更新日期：1993-03-22 00:00:00

abstract：:Two tandem cassettes, one containing the telomerase reverse transcriptase gene (hTERT) promoter upstream of a constitutively activated form of heat shock transcription factor 1 (cHSF1) and followed by the other containing the heat shock protein 70B (hsp70B) promoter (HSE) upstream of the cytosine deaminase (CD) gene, ...

journal_title：FEBS letters

authors： Wang J,Yao M,Zhang Z,Gu J,Zhang Y,Li B,Sun L,Liu X

更新日期：2003-07-10 00:00:00

abstract：:The replacement of O2 with CO was studied on cobalt-iron hemoglobin hybrids. Both proto- and mesocobalt hemes were used for the reconstitution. In the oxy quaternary conformation no difference is observed between alpha- and beta-subunits when only proto hemes are present in the hybrid (k4 = 30 s-1, k'4/l'4 = 2.5). If ...

journal_title：FEBS letters

authors： Oertle M,Winterhalter KH,Di Iorio EE

更新日期：1983-03-07 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 plays a pivotal role in mediating the nuclear export of KSHV intronless transcripts. We demonstrate that ORF57 localises and dynamically trafficks through the nucleolus. To assess if nucleolar shuttling of ORF57 is important for the export of intronless viral mRNA, ...

journal_title：FEBS letters

authors： Boyne JR,Whitehouse A

更新日期：2009-11-19 00:00:00

abstract：:The purpose of this investigation was to study the effect on cap structure for trans-splicing in mammalian cells. The early SV40 Bst/Bam pre-mRNA (cRNA) was synthesized in vitro in both capped (cap-Bst/Bam-cRNA) and non-capped (Bst/Bam-cRNA) versions and microinjected into the nuclei of TC7 cells. Trans-splicing was m...

journal_title：FEBS letters

authors： Graessmann M,Eul J,Berg B,Zimmermann C,Graessmann A

更新日期：1996-09-30 00:00:00

abstract：:The function of the coenzyme Q (CoQ) pool in the inner mitochondrial membrane is reviewed in view of recent findings suggesting a supramolecular organization of the mitochondrial respiratory complexes. In spite of the structural evidence for preferential aggregations of the inner membrane components, most kinetic evid...

journal_title：FEBS letters

authors： Lenaz G

更新日期：2001-12-07 00:00:00

abstract：:Stimulation of monocytes/macrophages with lipopolysaccharide (LPS) results in activation of nuclear factor-kappaB (NF-kappaB), which plays crucial roles in regulating expression of many genes involved in the subsequent inflammatory responses. Here, we investigated roles of transforming growth factor-beta activated kin...

journal_title：FEBS letters

authors： Irie T,Muta T,Takeshige K

更新日期：2000-02-11 00:00:00