Abstract:
:The replacement of O2 with CO was studied on cobalt-iron hemoglobin hybrids. Both proto- and mesocobalt hemes were used for the reconstitution. In the oxy quaternary conformation no difference is observed between alpha- and beta-subunits when only proto hemes are present in the hybrid (k4 = 30 s-1, k'4/l'4 = 2.5). If Co-meso heme is present on the beta-chains the binding properties of the partner subunit are modified (k'4/l'4 = 4).
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Oertle M,Winterhalter KH,Di Iorio EEdoi
10.1016/0014-5793(83)80150-1subject
Has Abstractpub_date
1983-03-07 00:00:00pages
213-6issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(83)80150-1journal_volume
153pub_type
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