Results of heavy ion radiotherapy.

Abstract:

:The potential of heavy ion therapy for clinical use in cancer therapy stems from the biological parameters of heavy charged particles and their precise dose localization. Biologically, carbon, neon, and other heavy ion beams (up to about silicon) are clinically useful in overcoming the radioresistance of hypoxic tumors, thus increasing the biological effectiveness relative to low linear energy transfer x-ray or electron beams. Cells irradiated by heavy ions show less variation in cell-cycle-related radiosensitivity and decreased repair of radiation injury. The physical parameters of these heavy charged particles allow precise delivery of high doses to tumors while minimizing irradiation of normal tissues. Clinical use requires a close interaction between radiation oncologists, medical physicists, accelerator physicists, engineers, computer scientists, and radiation biologists.

journal_name

Radiat Environ Biophys

authors

Castro JR

doi

10.1007/BF01210545

subject

Has Abstract

pub_date

1995-03-01 00:00:00

pages

45-8

issue

1

eissn

0301-634X

issn

1432-2099

journal_volume

34

pub_type

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