Quantitative analysis of DNA-damage response factors after sequential ion microirradiation.

abstract：:The oxyhemoglobin saturation (HbO2) of single red blood cells within tumor microvessels (diameter: 3-12 micrometers) of DS-Carcinosarcoma was studied using a cryophotometric micromethod. In untreated control tumors (mean tissue temperature approx. 35 degrees C) the measured values scattered over the whole saturation r...

journal_title：Radiation and environmental biophysics

authors： Vaupel PW,Otte J,Manz R

更新日期：1982-01-01 00:00:00

abstract：:The aim of this study was to detect membrane fluidity modifications in blood lymphocytes that had been exposed to gamma-radiation, at a graded series of depths from the surface to the centre of the membrane bilayer and as a function of cell viability. A time course was performed to verify the contribution of the membr...

journal_title：Radiation and environmental biophysics

authors： Vincent-Genod L,Benderitter M,Voisin P

更新日期：2001-09-01 00:00:00

abstract：:In order to provide fundamental data required for dose evaluation due to environmental exposures, effective dose conversion coefficients, that is, the effective dose rate per unit activity per unit area, were calculated for a number of potentially important radionuclides, assuming an exponential distribution in ground...

journal_title：Radiation and environmental biophysics

authors： Saito K,Ishigure N,Petoussi-Henss N,Schlattl H

更新日期：2012-11-01 00:00:00

abstract：:Many experimental studies are carried out to compare biological effectiveness of high dose rate (HDR) with that of low dose rate (LDR). The rational for this is the uncertainty regarding the value of the dose rate effectiveness factor (DREF) used in radiological protection. While a LDR is defined as 0.1 mGy/min or low...

journal_title：Radiation and environmental biophysics

authors： Olofsson D,Cheng L,Fernández RB,Płódowska M,Riego ML,Akuwudike P,Lisowska H,Lundholm L,Wojcik A

更新日期：2020-08-01 00:00:00

abstract：:The model of radiocaesium transfer to sheep presented by Galer et al. provides reliable predictions only for sheep of a similar body weight to those used in the development of the model (approximately 30 kg). To extend the applicability of the model, it was necessary to re-parameterise it in terms of activity concentr...

journal_title：Radiation and environmental biophysics

authors： Crout NM,Beresford NA,Howard BJ,Mayes RW,Assimakopoulos PA,Vandecasteele CM

更新日期：1996-02-01 00:00:00

abstract：:Waterborne radioactive releases into the Techa River from the Mayak Production Association in Russia during 1949-1956 resulted in significant doses to about 30,000 persons who lived in downstream settlements. The residents were exposed to internal and external radiation. Two methods for reconstruction of the external ...

journal_title：Radiation and environmental biophysics

authors： Degteva MO,Shagina NB,Shishkina EA,Vozilova AV,Volchkova AY,Vorobiova MI,Wieser A,Fattibene P,Della Monaca S,Ainsbury E,Moquet J,Anspaugh LR,Napier BA

更新日期：2015-11-01 00:00:00

abstract：:The effect of negative pions (peak and plateau), photons (140 kV and 29 MeV), and 20 MeV electrons on the proliferative capacity of Ehrlich ascites carcinoma cells was investigated. Proliferative survival curves plotted for the modalities employed are presented. Under the experimental conditions used, the peak pions w...

journal_title：Radiation and environmental biophysics

authors： Rao KR,Blattmann H,Cordt I,Fritz-Niggli H

更新日期：1979-08-10 00:00:00

abstract：:Large lung sections of humans of advanced adult age revealed a markedly nonuniform retention pattern of dense anthracotic particle aggregates, with an impressive accumulation of this material along pulmonary lymphatics, i.e. the deep (peribronchial), septal (perivenous) and superficial (pleural) networks. Conversely, ...

journal_title：Radiation and environmental biophysics

authors： Cottier H,Meister F,Zimmermann A,Kraft R,Burkhardt A,Gehr P,Poretti G

更新日期：1987-01-01 00:00:00

abstract：:In the mountainous "Hohe Tauern" region of Salzburg (Austria), milk samples have been collected in a long-term montitoring programme since 1988, at eight alpine sites used for extensive, seasonal stock farming. For this alpine environment with its acidic soils developed on silicate bedrock, high soil-to-plant transfer...

journal_title：Radiation and environmental biophysics

authors： Lettner H,Hubmer A,Bossew P,Strebl F,Steinhäusler F

更新日期：2009-02-01 00:00:00

abstract：:For radiation exposures employing targeted sources such as particle microbeams, the deposition of energy and dose will depend on the spatial heterogeneity of the sample. Although cell structural variations are relatively minor for two-dimensional cell cultures, they can vary significantly for fully differentiated tiss...

journal_title：Radiation and environmental biophysics

authors： Miller JH,Chrisler WB,Wang X,Sowa MB

更新日期：2011-08-01 00:00:00

abstract：:Activity concentrations of the selected radionuclides (40)K, (226)Ra and (232)Th were measured in surface soil samples collected from 38 cities in the southwest region of Nigeria by means of gamma spectroscopy with a high-purity germanium detector. Measured activity concentration values of (40)K varied from 34.9 +/- 4...

journal_title：Radiation and environmental biophysics

authors： Ajayi OS

更新日期：2009-08-01 00:00:00

abstract：:It is shown by UV absorption and absolute fluorescence spectroscopy of solutions containing both DNA and quinacrine that the components experience mutual radio-protection due to scavenging of water radicals. From measurements at different ionic strengths it is inferred that quinacrine bound to DNA is more efficiently ...

journal_title：Radiation and environmental biophysics

authors： Hissung A,Dertinger H,Heinrich G

更新日期：1975-06-13 00:00:00

abstract：:Model experiments with two structurally different proteins (alcohol dehydrogenase and salmine) show that glycine, alanine, and tyrosine are by far more frequently involved in photochemically induced cross-link formations with DNA than is cysteine. The yields for cross-link formation of thymidine with salmine (cysteine...

journal_title：Radiation and environmental biophysics

authors： Toth B,Dose K

更新日期：1976-07-30 00:00:00

abstract：:The root apex cells of Pisum sativum were irradiated in an U-240 isochronous cyclotron at the Institute for Nuclear Research of the Ukrainian National Academy of Sciences, Kyiv. Several types of micronuclei, differing in structural peculiarities, were observed in the 84 h following exposure to beams of accelerated 1H,...

journal_title：Radiation and environmental biophysics

authors： Vasilenko A,Sidorenko PG

更新日期：1995-06-01 00:00:00

abstract：:Because of the increasing application of ionizing radiation in medicine, quantitative data on effects of low-dose radiation are needed to optimize radiation protection, particularly with respect to cataract development. Using mice as mammalian animal model, we applied a single dose of 0, 0.063, 0.125 and 0.5 Gy at 10 ...

journal_title：Radiation and environmental biophysics

authors： Dalke C,Neff F,Bains SK,Bright S,Lord D,Reitmeir P,Rößler U,Samaga D,Unger K,Braselmann H,Wagner F,Greiter M,Gomolka M,Hornhardt S,Kunze S,Kempf SJ,Garrett L,Hölter SM,Wurst W,Rosemann M,Azimzadeh O,Tapio S,Au

更新日期：2018-05-01 00:00:00

abstract：:Within the Theory of Dual Radiation Action, the heuristically useful function, gamma(chi), that two energy depositions, a distance chi apart, will result in observable damage can be written in terms of two more fundamental quantities: One, s(chi), describes the structure of the sensitive matrix of the cell. The other,...

journal_title：Radiation and environmental biophysics

authors： Brenner DJ

更新日期：1988-01-01 00:00:00

abstract：:Radiocaesium absorption and retention in reindeer (Rangifer tarandus) calves was compared in groups fed diets containing different proportions of lichen and concentrates, and different chemical forms of radiocaesium ((134)CsCl in solution or fallout from the Chernobyl accident). Daily intakes of fallout radiocaesium w...

journal_title：Radiation and environmental biophysics

authors： Skuterud L,Pedersen Ø,Staaland H,Røed KH,Salbu B,Liken A,Hove K

更新日期：2004-12-01 00:00:00

abstract：:To explore possible applications of iodoacetate (IA), a glycolytic inhibitor, in cancer treatment, we screened its cytotoxicity and radioprotective/sensitizing efficacy in three different mammalian cell lines; A549 (human lung carcinoma), MCF7 (human mammary cancer), a non-cancerous CHO (Chinese hamster ovary) cells a...

journal_title：Radiation and environmental biophysics

authors： Yadav U,Anjaria KB,Nairy R,Shirsath KB,Desai UN,Chaurasia RK,Bhat NN,Sapra BK

更新日期：2017-08-01 00:00:00

abstract：:Age-specific and cumulative mortality rates are presented for different cancer sites from 1970 until 1988 for the 11 individual federal states of West Germany (FRG). Sex- and age-specific evaluations are performed and temporal and regional trends in mortality from different cancer sites are revealed. In the FRG there ...

journal_title：Radiation and environmental biophysics

authors： Kvasnicka J,Kvasnicka E,Schnadt H,Geuer W,Havers W,Breckow J

更新日期：1993-01-01 00:00:00

abstract：:Cosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime...

journal_title：Radiation and environmental biophysics

authors： Langner I,Blettner M,Gundestrup M,Storm H,Aspholm R,Auvinen A,Pukkala E,Hammer GP,Zeeb H,Hrafnkelsson J,Rafnsson V,Tulinius H,De Angelis G,Verdecchia A,Haldorsen T,Tveten U,Eliasch H,Hammar N,Linnersjö A

更新日期：2004-02-01 00:00:00

abstract：:Osteosarcoma is the most frequent secondary malignancy following radiotherapy of patients with bilateral retinoblastoma. This suggests that the Rb1 tumour suppressor gene might confer genetic susceptibility towards radiation-induced osteosarcoma. To define the contribution of the Rb1 pathway in the multistep process o...

journal_title：Radiation and environmental biophysics

authors： Gonzalez-Vasconcellos I,Domke T,Kuosaite V,Esposito I,Sanli-Bonazzi B,Nathrath M,Atkinson MJ,Rosemann M

更新日期：2011-03-01 00:00:00

abstract：:The Goiânia accident, Brazil, was used as an opportunity to quantify the contributions of different mechanisms, in particular mass loading, leading to caesium uptake by leafy vegetables in a semi-urban environment contaminated with 137Cs. Soil splash contributions of 70-90% were quantified for lettuce and 50-60% for g...

journal_title：Radiation and environmental biophysics

authors： Amaral EC,Paretzke HG,Campos MJ,Pires do Rio MA,Franklin M

更新日期：1994-01-01 00:00:00

abstract：:The article is devoted to the study of the role of intracellular mechanisms in the formation of radiation-induced genetic instability and its transgenerational effect in cells of different tissues of the descendants of Drosophila melanogaster mutant strains whose parents were exposed to chronic radiation (0.42 and 3.5...

journal_title：Radiation and environmental biophysics

authors： Yushkova E

更新日期：2020-05-01 00:00:00

abstract：:The relationship between occupational exposure to extremely low-frequency electromagnetic fields and adult leukaemia has been studied extensively during the last decade. The first studies were based on crude exposure assessments, estimated through job titles, with no or only limited control confounding factors. The re...

journal_title：Radiation and environmental biophysics

authors： Feychting M

更新日期：1996-11-01 00:00:00

abstract：:The main target of this work is to examine blood clearance and external exposure for 177Lu-DOTATATE compared with new emerging 177Lu-PSMA therapy. Blood clearance and radiation exposure of 31 patients treated with 5.5 ± 1.1 GBq 177Lu-DOTATATE were compared to those of 23 patients treated with 7.4 GBq 177Lu-PSMA. Dose ...

journal_title：Radiation and environmental biophysics

authors： Abuqbeitah M,Demir M,Uslu-Beşli L,Yeyin N,Sönmezoğlu K

更新日期：2018-03-01 00:00:00

abstract：:The method of iteratively reweighted least squares for the regression analysis of Poisson distributed chromosome aberration data is reviewed in the context of other fit procedures used in the cytogenetic literature. As an application of the resulting regression curves methods for calculating confidence intervals on do...

journal_title：Radiation and environmental biophysics

authors： Merkle W

更新日期：1983-01-01 00:00:00

abstract：:In spite of a well-known relationship between exposure to radiation and increased risk for cancer development, the biological mechanisms involved in radiation-induced carcinogenesis remain poorly documented. Various hypotheses are discussed in this paper. It appears that radiation cannot be directly responsible for th...

journal_title：Radiation and environmental biophysics

authors： Sabatier L,Lebeau J,Dutrillaux B

更新日期：1995-11-01 00:00:00

abstract：:The objective of the present work is to apply the plasma clearance parameters to strontium, previously determined in our laboratory, to improve the biokinetic and dosimetric models of strontium-90 ((90)Sr) used in radiological protection; and also to apply this data for the estimation of the radiation doses from stron...

journal_title：Radiation and environmental biophysics

authors： Li WB,Höllriegl V,Roth P,Oeh U

更新日期：2008-04-01 00:00:00

abstract：:Responses of the S/S variant of the L5178Y murine leukemic lymphoblast, the photoreceptor cell of the rabbit retina and the lenticular epithelium of the rabbit to heavy ions (20Ne, 28Si, 40Ar and 56Fe) are described and discussed primarily from the standpoint of the need for a comprehensive theory of cellular radiosen...

journal_title：Radiation and environmental biophysics

authors： Lett JT,Cox AB,Bergtold DS

更新日期：1986-01-01 00:00:00

abstract：:In the work presented here, changes in haematopoiesis of mice (B6129SF2/J) were studied 1 year after their whole-body exposure to a dose of 7 Gy (72% of mice survived). The irradiated mice were compared with non-irradiated younger (4 months of age) and older (16 months of age) mice. There was a significant increase in...

journal_title：Radiation and environmental biophysics

authors： Vávrová J,Sinkorová Z,Rezáčová M,Tichý A,Filip S,Mokrý J,Lukášová E

更新日期：2012-05-01 00:00:00