Differential killing and radio-modifying effects of iodoacetate in mammalian normal and cancer cells.

abstract：:The biological phenomena observed at low doses of ionizing radiation (adaptive response, bystander effects, genomic instability, etc.) are still not well understood. While at high irradiation doses, cellular death may be directly linked to DNA damage, at low doses, other cellular structures may be involved in what are...

journal_title：Radiation and environmental biophysics

authors： Cunha M,Testa E,Komova OV,Nasonova EA,Mel'nikova LA,Shmakova NL,Beuve M

更新日期：2016-03-01 00:00:00

abstract：:The potential of proton microchannel radiotherapy to reduce radiation effects in the healthy tissue but to keep tumor control the same as in conventional proton therapy is further elucidated. The microchannels spread on their way to the tumor tissue resulting in different fractions of the healthy tissue covered with d...

journal_title：Radiation and environmental biophysics

authors： Girst S,Greubel C,Reindl J,Siebenwirth C,Zlobinskaya O,Dollinger G,Schmid TE

更新日期：2015-08-01 00:00:00

abstract：:Blue (F450) and green (F530) leaf fluorescence were studied together with the red chlorophyll fluorescence (emission maxima F690 and F735) during light-induced chlorophyll fluorescence induction kinetics (Kautsky effect) in predarkened leaves of wheat (Triticum aestivum L.) and soybean (Glycine max L.). The intensity ...

journal_title：Radiation and environmental biophysics

authors： Stober F,Lichtenthaler HK

更新日期：1993-01-01 00:00:00

abstract：:The evolution of the proflavine triplet state population with the extent of aggregation is examines, by ESRmeasurements, as a function of organic solvents and mineral salts, well known for their ability to influence the aggregation process. The intensity of the triplet state population has also been investigated as a ...

journal_title：Radiation and environmental biophysics

authors： Lion Y,Saucin M,Van de Vorst A

更新日期：1975-12-04 00:00:00

abstract：:The fluorescent intercalation complex of ethidium bromide with DNA was used as a probe to demonstrate damage in the base-pair region of DNA, due to the action of superoxide radicals. The O.2- radical itself, generated by gamma-radiolysis of oxygenated aqueous Na-formate solutions, is rather ineffective with respect to...

journal_title：Radiation and environmental biophysics

authors： Prütz WA

更新日期：1984-01-01 00:00:00

abstract：:After ingestion or inhalation of radionuclides, internal organs of the human body will be exposed to ionising radiation. Current risk estimates of radiation-associated cancer from internal emitters are largely based on extrapolation of risk from high-dose externally exposed groups. Concerns have been expressed that ex...

journal_title：Radiation and environmental biophysics

authors： Little MP,Hall P,Charles MW

更新日期：2007-11-01 00:00:00

abstract：:The major goal of this study was to identify and quantitatively describe the association between the characteristics of chronic (low-dose rate) exposure to (low LET) ionizing radiation and cellularity of peripheral blood cell lines. About 3,200 hemograms (i.e., spectra of blood counts) obtained over the years of maxim...

journal_title：Radiation and environmental biophysics

authors： Akleyev AV,Akushevich IV,Dimov GP,Veremeyeva GA,Varfolomeyeva TA,Ukraintseva SV,Yashin AI

更新日期：2010-05-01 00:00:00

abstract：:Waterborne radioactive releases into the Techa River from the Mayak Production Association in Russia during 1949-1956 resulted in significant doses to about 30,000 persons who lived in downstream settlements. The residents were exposed to internal and external radiation. Two methods for reconstruction of the external ...

journal_title：Radiation and environmental biophysics

authors： Degteva MO,Shagina NB,Shishkina EA,Vozilova AV,Volchkova AY,Vorobiova MI,Wieser A,Fattibene P,Della Monaca S,Ainsbury E,Moquet J,Anspaugh LR,Napier BA

更新日期：2015-11-01 00:00:00

abstract：:Radiocaesium absorption and retention in reindeer (Rangifer tarandus) calves was compared in groups fed diets containing different proportions of lichen and concentrates, and different chemical forms of radiocaesium ((134)CsCl in solution or fallout from the Chernobyl accident). Daily intakes of fallout radiocaesium w...

journal_title：Radiation and environmental biophysics

authors： Skuterud L,Pedersen Ø,Staaland H,Røed KH,Salbu B,Liken A,Hove K

更新日期：2004-12-01 00:00:00

abstract：:In mice, persisting radiation-induced growth retardation of hematopoietic tissue suggested that at least part of the surviving stem cells are genetically injured. Additional mitotic stress some time after the radiation insult might remove injured stem cells, thus improving the overall recovery of the irradiated bone m...

journal_title：Radiation and environmental biophysics

authors： von Wangenheim KH,Peterson HP,Cronkite EP,Feinendegen LE

更新日期：1987-01-01 00:00:00

abstract：:During anthropogenic activities, such as agricultural soil management and traffic on unpaved roads, size distribution measurements were performed of atmospheric particulate radionuclides at a site in the Chernobyl 30-km exclusion zone. Analysis of cascade impactor measurements showed an increase of the total atmospher...

journal_title：Radiation and environmental biophysics

authors： Garger EK,Paretzke HG,Tschiersch J

更新日期：1998-10-01 00:00:00

abstract：:The aim of this interdisciplinary project is to establish slice culture preparations from rodents and humans as a new model system for studying effects of X-rays and heavy ions within normal and tumor tissues. The advantage of such slice cultures relies on the conservation of an organotypic environment, the easy treat...

journal_title：Radiation and environmental biophysics

authors： Merz F,Müller M,Taucher-Scholz G,Rödel F,Stöcker H,Schopow K,Laprell L,Dehghani F,Durante M,Bechmann I

更新日期：2010-08-01 00:00:00

abstract：:Analyses of structural aberrations of chromosomes and of the body burden of lead-210 were carried out in a group of workers occupationally exposed to chemical pollutants and low doses of ionizing radiation during a technological process in which coal is used as fuel. A parallel study was performed in a control group o...

journal_title：Radiation and environmental biophysics

authors： Horvat D,Bauman A,Racić J

更新日期：1980-01-01 00:00:00

abstract：:Within the Theory of Dual Radiation Action, the heuristically useful function, gamma(chi), that two energy depositions, a distance chi apart, will result in observable damage can be written in terms of two more fundamental quantities: One, s(chi), describes the structure of the sensitive matrix of the cell. The other,...

journal_title：Radiation and environmental biophysics

authors： Brenner DJ

更新日期：1988-01-01 00:00:00

abstract：:Several proteins are known to form foci at DNA sites damaged by ionizing radiation. We study DNA damage response by immunofluorescence microscopy after microirradiation of cells with energetic ions. By using microirradiation, it is possible to irradiate different regions on a single dish at different time-points and t...

journal_title：Radiation and environmental biophysics

authors： Greubel C,Hable V,Drexler GA,Hauptner A,Dietzel S,Strickfaden H,Baur I,Krücken R,Cremer T,Friedl AA,Dollinger G

更新日期：2008-11-01 00:00:00

abstract：:An inter-comparison of five models designed to predict the effect of ionizing radiation on populations of non-human wildlife, performed under the IAEA EMRAS II programme, is presented and discussed. A benchmark scenario 'Population response to chronic irradiation' was developed in which stable generic populations of m...

journal_title：Radiation and environmental biophysics

authors： Vives I Batlle J,Sazykina TG,Kryshev A,Monte L,Kawaguchi I

更新日期：2012-11-01 00:00:00

abstract：:The use of Green's function has played a fundamental role in transport calculations for high-charge high-energy (HZE) ions. Two recent developments have greatly advanced the practical aspects of implementation of these methods. The first was the formulation of a closed-form solution as a multiple fragmentation perturb...

journal_title：Radiation and environmental biophysics

authors： Shinn JL,Wilson JW,Schimmerling W,Shavers MR,Miller J,Benton EV,Frank AL,Badavi FF

更新日期：1995-08-01 00:00:00

abstract：:Preliminary results on the spectral dependence of the absorption of light in tissue are presented and discussed with respect to medical laser application. ...

journal_title：Radiation and environmental biophysics

authors： Eichler J,Knof J,Lenz H

更新日期：1977-10-12 00:00:00

abstract：:The aim of this study was to detect membrane fluidity modifications in blood lymphocytes that had been exposed to gamma-radiation, at a graded series of depths from the surface to the centre of the membrane bilayer and as a function of cell viability. A time course was performed to verify the contribution of the membr...

journal_title：Radiation and environmental biophysics

authors： Vincent-Genod L,Benderitter M,Voisin P

更新日期：2001-09-01 00:00:00

abstract：:The aim of this work was to define the possible occurrence of hematological changes during the course of a chronic ingestion of (137)Cs. A mouse model was used, with ingestion through drinking water with a cesium concentration of 20 kBq l(-1). Ingestion started in parent animals before mating, and (137)Cs intake and i...

journal_title：Radiation and environmental biophysics

authors： Bertho JM,Louiba S,Faure MC,Tourlonias E,Stefani J,Siffert B,Paquet F,Dublineau I

更新日期：2010-05-01 00:00:00

abstract：:The migration of radionuclides from waste repositories to the biosphere potentially leads to a contamination of soil. Due to the importance of food production, the mobilisation and accumulation behaviour of long-lived radionuclides in the soil plays a key role in performance assessment studies. In this paper, the main...

journal_title：Radiation and environmental biophysics

authors： Koch-Steindl H,Pröhl G

更新日期：2001-06-01 00:00:00

abstract：:The non-cancer mortality data for cerebrovascular disease (CVD) and cardiovascular diseases from Report 13 on the atomic bomb survivors published by the Radiation Effects Research Foundation were analysed to investigate the dose-response for the influence of radiation on these detrimental health effects. Various param...

journal_title：Radiation and environmental biophysics

authors： Schöllnberger H,Kaiser JC,Jacob P,Walsh L

更新日期：2012-05-01 00:00:00

abstract：:To evaluate the dose distributions of an electron microbeam and to help optimization of its design, the condensed-history (CH) Monte Carlo simulation algorithm implemented in the Geant4 toolkit was selected as an alternative to the conventionally used analog algorithm. Compared to the analog algorithm, the CH algorith...

journal_title：Radiation and environmental biophysics

authors： Ma Y,Zhou H,Zhuo Y

更新日期：2006-03-01 00:00:00

abstract：:This work describes the radiological assessment of the near-surface Maisiagala radioactive waste repository (Lithuania) over the period 2005-2012, with focus on water pathways and special emphasis on tritium. The study includes an assessment of the effect of post-closure upgrading, the durability of which is greater t...

journal_title：Radiation and environmental biophysics

authors： Nedveckaite T,Gudelis A,Vives i Batlle J

更新日期：2013-05-01 00:00:00

abstract：:Radiation is known to be carcinogenic to humans but attempts to demonstrate the process using human tissue culture models have met with little success. In the present study explants were established from urothelium and exposed to radiation and a range of chemical carcinogens, suspected promotor or metabolic agents. Th...

journal_title：Radiation and environmental biophysics

authors： Mothersill C,O'Brien A,Seymour CB

更新日期：1990-01-01 00:00:00

abstract：:In spite of a well-known relationship between exposure to radiation and increased risk for cancer development, the biological mechanisms involved in radiation-induced carcinogenesis remain poorly documented. Various hypotheses are discussed in this paper. It appears that radiation cannot be directly responsible for th...

journal_title：Radiation and environmental biophysics

authors： Sabatier L,Lebeau J,Dutrillaux B

更新日期：1995-11-01 00:00:00

abstract：:The hypoxic cytotoxic effect of chlorpromazine towards E. coli B/r was observed to be dependent on temperature of incubation and irradiation. Increasing the temperature of incubation from ambient to 37 degrees C followed by irradiation revealed that the organisms showed radiosensitivity of a magnitude which was two to...

journal_title：Radiation and environmental biophysics

authors： Shenoy MA,Singh BB

更新日期：1985-01-01 00:00:00

abstract：:Quantitative cancer incidence data exist for various laboratory animal models, but little of this information is usable for estimating human risks, primarily because of uncertainties about possible mechanistic differences among species. Acceptance and utilization of animal data for human risk assessment will require a...

journal_title：Radiation and environmental biophysics

authors： Burns FJ,Tang MS,Frenkel K,Nádas A,Wu F,Uddin A,Zhang R

更新日期：2007-06-01 00:00:00

abstract：:With a model system of pBR322 plasmid DNA solution in vitro, the dose effects of radiation-induced single- and double-strand breaks (SSB and DSB) were measured and DSB was distinguished into alpha- and beta-types. Under the condition of low scavenging capacity existing in the irradiated DNA solution, SSB and alpha DSB...

journal_title：Radiation and environmental biophysics

authors： Shao C,Yu Z,Saito M

更新日期：2000-06-01 00:00:00

abstract：:The study reported in the present paper aimed to evaluate the effective energy (Eeff) of X-rays emitted from the surface of a bare X-ray probe and from different spherical applicators with various diameters, which are widely employed for low kV intraoperative radiotherapy (IORT) of breast cancer. A previously validate...

journal_title：Radiation and environmental biophysics

authors： Shamsabadi R,Baghani HR,Mowlavi AA,Azadegan B

更新日期：2021-01-03 00:00:00