Tissue slice cultures from humans or rodents: a new tool to evaluate biological effects of heavy ions.

abstract：:The effects of single pulses and multiple pulses of 7 MV electrons on micronuclei (MN) induction in cytokinesis-blocked human peripheral blood lymphocytes (PBLs) were investigated over a wide range of dose rates per pulse (instantaneous dose rate). PBLs were exposed to graded doses of 2, 3, 4, 6, and 8 Gy of single el...

journal_title：Radiation and environmental biophysics

authors： Acharya S,Bhat NN,Joseph P,Sanjeev G,Sreedevi B,Narayana Y

更新日期：2011-05-01 00:00:00

abstract：:Simple, ellipsoidal geometries have long been the standard for estimating radiation dose rates in non-human biota (NHB). With the introduction of a regulatory protection standard that emphasizes protection of NHB as its own end point, there has been interest in improved models for the calculation of dose rates in NHB....

journal_title：Radiation and environmental biophysics

authors： Ruedig E,Caffrey E,Hess C,Higley K

更新日期：2014-08-01 00:00:00

abstract：:The model of radiocaesium transfer to sheep presented by Galer et al. provides reliable predictions only for sheep of a similar body weight to those used in the development of the model (approximately 30 kg). To extend the applicability of the model, it was necessary to re-parameterise it in terms of activity concentr...

journal_title：Radiation and environmental biophysics

authors： Crout NM,Beresford NA,Howard BJ,Mayes RW,Assimakopoulos PA,Vandecasteele CM

更新日期：1996-02-01 00:00:00

abstract：:The TEL1 gene from Saccharomyces cerevisiae has been shown to be the closest sequence homologue to ATM, the gene mutated in ataxia-telangiectasia (A-T) patients. Functional homology shared between the ATM and Tell proteins has recently been demonstrated based on heterologous expression of the TEL1 gene in human cells ...

journal_title：Radiation and environmental biophysics

authors： Cao JP,Meyn MS,Eckardt-Schupp F,Fritz E

更新日期：2001-12-01 00:00:00

abstract：:Native horseradish peroxidase, as well as its reduced and carboxymethylated form, and the apoenzyme, showed resistance to photodynamic action. Sensitivity to this action was detected only in reduced and carboxymethylated apoenzyme, when the photooxidation of its histidine residues was observed. When analyzing the bulk...

journal_title：Radiation and environmental biophysics

authors： Silva E,Barrera M

更新日期：1985-01-01 00:00:00

abstract：:An inter-comparison of five models designed to predict the effect of ionizing radiation on populations of non-human wildlife, performed under the IAEA EMRAS II programme, is presented and discussed. A benchmark scenario 'Population response to chronic irradiation' was developed in which stable generic populations of m...

journal_title：Radiation and environmental biophysics

authors： Vives I Batlle J,Sazykina TG,Kryshev A,Monte L,Kawaguchi I

更新日期：2012-11-01 00:00:00

abstract：:In the work presented here, changes in haematopoiesis of mice (B6129SF2/J) were studied 1 year after their whole-body exposure to a dose of 7 Gy (72% of mice survived). The irradiated mice were compared with non-irradiated younger (4 months of age) and older (16 months of age) mice. There was a significant increase in...

journal_title：Radiation and environmental biophysics

authors： Vávrová J,Sinkorová Z,Rezáčová M,Tichý A,Filip S,Mokrý J,Lukášová E

更新日期：2012-05-01 00:00:00

abstract：:An LBO (Li2B4O7) walled ionization chamber was designed to monitor the epithermal neutron fluence in boron neutron capture therapy clinical irradiation. The thermal and epithermal neutron sensitivities of the device were evaluated using accelerator neutrons from the 9Be(d, n) reaction at a deuteron energy of 4 MeV (4 ...

journal_title：Radiation and environmental biophysics

authors： Endo S,Sato H,Shimazaki T,Nakajima E,Kotani K,Suda M,Hamano T,Kajimoto T,Tanaka K,Hoshi M

更新日期：2017-08-01 00:00:00

abstract：:Investigation of cell-free DNA (cf-DNA) in body fluids, as a potential biomarker for assessing the effect of ionizing radiation on the organism, is of considerable interest. We investigated changes in the contents of cell-free mitochondrial DNA (cf-mtDNA) and cell-free nuclear DNA (cf-nDNA) in the urine of X-ray-expos...

journal_title：Radiation and environmental biophysics

authors： Abdullaev SA,Minkabirova GM,Bezlepkin VG,Gaziev AI

更新日期：2015-08-01 00:00:00

abstract：:Cosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime...

journal_title：Radiation and environmental biophysics

authors： Langner I,Blettner M,Gundestrup M,Storm H,Aspholm R,Auvinen A,Pukkala E,Hammer GP,Zeeb H,Hrafnkelsson J,Rafnsson V,Tulinius H,De Angelis G,Verdecchia A,Haldorsen T,Tveten U,Eliasch H,Hammar N,Linnersjö A

更新日期：2004-02-01 00:00:00

abstract：:In this work, direct DNA damage induced by low-energy electrons (<5 keV) is simulated using Monte Carlo methods, and the resulting yield of various strand breaks and base damages in cellular environment is presented. The simulation is based on a new inelastic cross section for the production of electron track structur...

journal_title：Radiation and environmental biophysics

authors： Zhang L,Tan Z

更新日期：2010-03-01 00:00:00

abstract：:In order to provide fundamental data required for dose evaluation due to environmental exposures, effective dose conversion coefficients, that is, the effective dose rate per unit activity per unit area, were calculated for a number of potentially important radionuclides, assuming an exponential distribution in ground...

journal_title：Radiation and environmental biophysics

authors： Saito K,Ishigure N,Petoussi-Henss N,Schlattl H

更新日期：2012-11-01 00:00:00

abstract：:The rare earth radionuclides 177 Lu and 153Sm were administered as single i.p. injections in NMRI mice. Lu was deposited principally (up to 60%) in the skeleton if the quantity of stable carrier was low. Increase of stable carrier enhanced deposition in the reticulo-endothelial system. Sm was preferentially deposited ...

journal_title：Radiation and environmental biophysics

authors： Müller WA,Scháffer EH,Linzner U

更新日期：1980-01-01 00:00:00

abstract：:The probability of the formation of ionization clusters by primary alpha-particles at 5.4 MeV in nanometric volumes of propane was studied experimentally and by Monte Carlo simulation, as a function of the distance between the center line of the particle beam and the center of the target volume. The volumes were of cy...

journal_title：Radiation and environmental biophysics

authors： De Nardo L,Colautti P,Conte V,Baek WY,Grosswendt B,Tornielli G

更新日期：2002-12-01 00:00:00

abstract：:In mice, persisting radiation-induced growth retardation of hematopoietic tissue suggested that at least part of the surviving stem cells are genetically injured. Additional mitotic stress some time after the radiation insult might remove injured stem cells, thus improving the overall recovery of the irradiated bone m...

journal_title：Radiation and environmental biophysics

authors： von Wangenheim KH,Peterson HP,Cronkite EP,Feinendegen LE

更新日期：1987-01-01 00:00:00

abstract：:The aim of this study was to verify whether extremely low frequency (ELF) magnetic fields (MF) could affect transposition activity like some environmental stress factors such as heat shock or UV irradiation. Using an Escherichia coli Lac Z(-) strain transformed with a plasmid containing a Tn 10 derivative element expr...

journal_title：Radiation and environmental biophysics

authors： Del Re B,Garoia F,Mesirca P,Agostini C,Bersani F,Giorgi G

更新日期：2003-07-01 00:00:00

abstract：:To explore possible applications of iodoacetate (IA), a glycolytic inhibitor, in cancer treatment, we screened its cytotoxicity and radioprotective/sensitizing efficacy in three different mammalian cell lines; A549 (human lung carcinoma), MCF7 (human mammary cancer), a non-cancerous CHO (Chinese hamster ovary) cells a...

journal_title：Radiation and environmental biophysics

authors： Yadav U,Anjaria KB,Nairy R,Shirsath KB,Desai UN,Chaurasia RK,Bhat NN,Sapra BK

更新日期：2017-08-01 00:00:00

abstract：:Microcalorimetric experiments on growth and maintenance metabolism of Saccharomyces strains ranging from haploid to hexaploid are described. During growth, the mean dry weight, the mean volume and the maximum heat flux of the cells are nearly linear functions of ploidy. These parameters are correlated with the cell co...

journal_title：Radiation and environmental biophysics

authors： Lamprecht I,Schaarschmidt B,Welge G

更新日期：1976-03-30 00:00:00

abstract：:Osteosarcoma is the most frequent secondary malignancy following radiotherapy of patients with bilateral retinoblastoma. This suggests that the Rb1 tumour suppressor gene might confer genetic susceptibility towards radiation-induced osteosarcoma. To define the contribution of the Rb1 pathway in the multistep process o...

journal_title：Radiation and environmental biophysics

authors： Gonzalez-Vasconcellos I,Domke T,Kuosaite V,Esposito I,Sanli-Bonazzi B,Nathrath M,Atkinson MJ,Rosemann M

更新日期：2011-03-01 00:00:00

abstract：:It is usually assumed that sparsely ionizing radiation produces randomly distributed DNA breakages. This seems to be supported by the finding that in some DNA fragments single-strand scissions occur uniformly at all nucleotide sites, regardless of sequence. We performed experiments on two DNA fragments of about 300 bp...

journal_title：Radiation and environmental biophysics

authors： Barone F,Belli M,Mazzei F

更新日期：1994-01-01 00:00:00

abstract：:It has generally been assumed that the neutron and γ-ray absorbed doses in the data from the life span study (LSS) of the Japanese A-bomb survivors are too highly correlated for an independent separation of the all solid cancer risks due to neutrons and due to γ-rays. However, with the release of the most recent data ...

journal_title：Radiation and environmental biophysics

authors： Walsh L

更新日期：2013-03-01 00:00:00

abstract：:Age-specific and cumulative mortality rates are presented for different cancer sites from 1970 until 1988 for the 11 individual federal states of West Germany (FRG). Sex- and age-specific evaluations are performed and temporal and regional trends in mortality from different cancer sites are revealed. In the FRG there ...

journal_title：Radiation and environmental biophysics

authors： Kvasnicka J,Kvasnicka E,Schnadt H,Geuer W,Havers W,Breckow J

更新日期：1993-01-01 00:00:00

abstract：:About a century ago, Conrad Röentgen discovered X-rays, and Henri Becquerel discovered a new phenomenon, which Marie and Pierre Curie later coined as radio-activity. Since their seminal work, we have learned much about the physical properties of radiation and its effects on living matter. Alas, the more we discover, t...

journal_title：Radiation and environmental biophysics

authors： Feinendegen L,Hahnfeldt P,Schadt EE,Stumpf M,Voit EO

更新日期：2008-02-01 00:00:00

abstract：:It is shown that the properties of ATPase (EC 3.6.1.3) of Micrococcus luteus depend only to some extent on the state of the membrane to which it is attached. Its interaction with the membrane appears to be largely controlled by polar forces. It is shown, however, that the UV-sensitivity of the membrane-bound ATPase is...

journal_title：Radiation and environmental biophysics

authors： Volotovskij J,Risi S,Dose K

更新日期：1976-03-30 00:00:00

abstract：:The results of a study in which groups of sheep were given single oral administrations of 14C, 3H and 35S and then slaughtered over a period of 1 year are reported. The experimental data were used to investigate the potential of metabolically based models for describing the transfer of the three radionuclides to sheep...

journal_title：Radiation and environmental biophysics

authors： Crout NM,Mayes RW,Beresford NA,Lamb CS,Howard BJ

更新日期：1998-02-01 00:00:00

abstract：:Recent analyses of the Canadian fluoroscopy cohort study reported significantly increased radiation risks of mortality from ischemic heart diseases (IHD) with a linear dose-response adjusted for dose fractionation. This cohort includes 63,707 tuberculosis patients from Canada who were exposed to low-to-moderate dose f...

journal_title：Radiation and environmental biophysics

authors： Schöllnberger H,Kaiser JC,Eidemüller M,Zablotska LB

更新日期：2020-03-01 00:00:00

abstract：:Since the early 1990s, information on radiation-exposed populations other than those exposed from the Chernobyl accident in 1986 has become increasingly available for international scientific research. It is essential to understand how the cohorts of exposed populations have been defined and what mechanisms can be use...

journal_title：Radiation and environmental biophysics

authors： Winkelmann RA,Tretyakov FD,Startsev NV,Kolyado IB,Gusev BI,Grosche B,Storm HH,Hall P

更新日期：2002-03-01 00:00:00

abstract：:For radiation exposures employing targeted sources such as particle microbeams, the deposition of energy and dose will depend on the spatial heterogeneity of the sample. Although cell structural variations are relatively minor for two-dimensional cell cultures, they can vary significantly for fully differentiated tiss...

journal_title：Radiation and environmental biophysics

authors： Miller JH,Chrisler WB,Wang X,Sowa MB

更新日期：2011-08-01 00:00:00

abstract：:In this work, direct DNA damage induced by low-energy electrons (sub-keV) is simulated using a Monte Carlo method. The characteristics of the present simulation are to consider the new mechanism of DNA damage due to dissociative electron attachment (DEA) and to allow determining damage to specific bases (i.e., adenine...

journal_title：Radiation and environmental biophysics

authors： Liu W,Tan Z,Zhang L,Champion C

更新日期：2017-03-01 00:00:00

abstract：:Microcalorimetry, in combination with conventional methods for determining metabolic activity, opens the possibility to study the efficiency with which ATP, produced as a result of metabolic activity, is utilized by the cell for energy-requiring synthetic reactions. Using commercial baker's yeast as a test organism an...

journal_title：Radiation and environmental biophysics

authors： Hoogerheide JC

更新日期：1975-12-04 00:00:00