Temperature dependent modification of radiosensitivity following hypoxic cytocidal action of chlorpromazine.

Abstract:

:The hypoxic cytotoxic effect of chlorpromazine towards E. coli B/r was observed to be dependent on temperature of incubation and irradiation. Increasing the temperature of incubation from ambient to 37 degrees C followed by irradiation revealed that the organisms showed radiosensitivity of a magnitude which was two to three times the oxygen effect. The possible mechanisms of this effect are discussed.

journal_name

Radiat Environ Biophys

authors

Shenoy MA,Singh BB

doi

10.1007/BF01229816

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

113-7

issue

2

eissn

0301-634X

issn

1432-2099

journal_volume

24

pub_type

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