Abstract:
:Cosmic radiation is an occupational risk factor for commercial aircrews. In this large European cohort study (ESCAPE) its association with cancer mortality was investigated on the basis of individual effective dose estimates for 19,184 male pilots. Mean annual doses were in the range of 2-5 mSv and cumulative lifetime doses did not exceed 80 mSv. All-cause and all-cancer mortality was low for all exposure categories. A significant negative risk trend for all-cause mortality was seen with increasing dose. Neither external and internal comparisons nor nested case-control analyses showed any substantially increased risks for cancer mortality due to ionizing radiation. However, the number of deaths for specific types of cancer was low and the confidence intervals of the risk estimates were rather wide. Difficulties in interpreting mortality risk estimates for time-dependent exposures are discussed.
journal_name
Radiat Environ Biophysjournal_title
Radiation and environmental biophysicsauthors
Langner I,Blettner M,Gundestrup M,Storm H,Aspholm R,Auvinen A,Pukkala E,Hammer GP,Zeeb H,Hrafnkelsson J,Rafnsson V,Tulinius H,De Angelis G,Verdecchia A,Haldorsen T,Tveten U,Eliasch H,Hammar N,Linnersjö Adoi
10.1007/s00411-003-0214-7keywords:
subject
Has Abstractpub_date
2004-02-01 00:00:00pages
247-56issue
4eissn
0301-634Xissn
1432-2099journal_volume
42pub_type
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