Enamel matrix proteins and ameloblast biology.

abstract：:Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal li...

journal_title：Connective tissue research

authors： Cho H,Tarafder S,Fogge M,Kao K,Lee CH

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The presence of genetic variants in uric acid (UA) transporters can be associated with hyperuricemia, and therefore with an increased risk of monosodium urate (MSU) crystal precipitation. The inflammatory process triggered by these crystals leads to cartilage damage, which, in turn, could promote knee osteoa...

journal_title：Connective tissue research

authors： Fernández-Torres J,Martínez-Nava GA,Oliviero F,López-Reyes AG,Martínez-Flores K,Garrido-Rodríguez D,Francisco-Balderas A,Zamudio-Cuevas Y

更新日期：2019-05-01 00:00:00

abstract：:Oral mandibular epithelium determines the position and number of tooth organs. Cranial neural crest-derived ectomesenchyme provides inductive signals for (i) tooth shape, and (ii) sequential determination and expression of several different epithelial-derived enamel proteins. Inductive signalling follows a precise seq...

journal_title：Connective tissue research

authors： Slavkin HC

更新日期：1989-01-01 00:00:00

abstract：:Activation of protein kinase C (PKC) can upregulate tooth eruption molecules such as osteoprotegerin (OPG) and vascular endothelial growth factor (VEGF). In this study, we examined the in vivo gene expression of classic isoforms of PKC in the dental follicle of postnatal rats. The expression level of PKC-alpha was sig...

journal_title：Connective tissue research

authors： Yao S,Wise G

更新日期：2004-01-01 00:00:00

abstract：:Degeneration of the intervertebral discs, a natural progression of the aging process, is strongly implicated as a cause of low back pain. Aggrecan is the major structural proteoglycan in the extracellular matrix of the intervertebral disc. It is large, possessing numerous glycosaminoglycan chains and the ability to fo...

journal_title：Connective tissue research

authors： Wei Q,Zhang X,Zhou C,Ren Q,Zhang Y

更新日期：2019-05-01 00:00:00

abstract：:Fras1 and the structurally related proteins Frem1, Frem2, and Frem3, comprise a novel family of extracellular matrix proteins, which localize in a similar fashion underneath the lamina densa of epithelial basement membranes. They are involved in the structural adhesion of the skin epithelium to its underlying mesenchy...

journal_title：Connective tissue research

authors： Petrou P,Makrygiannis AK,Chalepakis G

更新日期：2008-01-01 00:00:00

abstract：:The experiments described herein tested the effects of CaCl2 and ZnCl2, added at various concentrations in the culture medium, upon the synthesis of collagen and proteoglycan by adult and fetal (articular, epiphyseal and hypertrophic) bovine chondrocytes maintained in high density multilayer cultures. CaCl2 concentrat...

journal_title：Connective tissue research

authors： Koyano Y,Hejna M,Flechtenmacher J,Schmid TM,Thonar EJ,Mollenhauer J

更新日期：1996-01-01 00:00:00

abstract：:Studies were designed to test the hypothesis that plasma- and serum-deprived embryonic cells and tissues in vitro are capable of producing growth regulating factors which augment cartilage, bone and tooth induction during mouse mandibular process development. Embryonic mouse first branchial arch-derived mandibular pro...

journal_title：Connective tissue research

authors： Slavkin HC,Sasano Y,Kikunaga S,Bessem C,Bringas P Jr,Mayo M,Luo W,Mak G,Rall L,Snead ML

更新日期：1990-01-01 00:00:00

abstract：:The relationship between structural changes and hyaluronic acid (HA) content in muscular atrophy is unknown. The objective of our study was to conduct multifaceted evaluations of the change in muscle extensibility in muscular atrophy, in terms of morphological aspects as well as from a biochemical viewpoint, including...

journal_title：Connective tissue research

authors： Ishikawa T,Shimizu M,Mikawa Y,Zhu BL,Quan L,Li DR,Zhao D,Maeda H

更新日期：2005-01-01 00:00:00

abstract：:The turnover of proteoglycans in bovine articular cartilage was determined in explant cultures, maintained at 32 degrees C or 37 degrees C. Both the rate of proteoglycan synthesis and the release of newly synthesized proteoglycans were decreased in cultures incubated at 32 degrees C compared to 37 degrees C. At both t...

journal_title：Connective tissue research

authors： Brand HS,De Koning MH,van Kampen GP,Van der Korst JK

更新日期：1991-01-01 00:00:00

abstract：:Collagen type I fiber-based scaffolds for anterior cruciate ligament (ACL) replacement were evaluated for their mechanical properties and their ability to promote cellular proliferation. Prior to scaffold formation, two crosslinking methods were investigated on individual reconstituted collagen type I fibers, ultravio...

journal_title：Connective tissue research

authors： Walters VI,Kwansa AL,Freeman JW

更新日期：2012-01-01 00:00:00

abstract：:This investigation is devoted to the study of the viscoelastic behavior of human abdominal fascia from the umbilical region. Seventeen samples 10 mm wide and up to 70 mm long were cut along the primary fiber direction (group FL) or perpendicular to it (group FT) and subjected to relaxation tests. The viscoelastic resp...

journal_title：Connective tissue research

authors： Kirilova M

更新日期：2012-01-01 00:00:00

abstract：:We demonstrated the cells producing collagenase and the time course of collagenase-production at early stages of wound healing, using histology and two immunohistochemical procedures on cross sections of rat skin harvested 0, 3, 5, 7 and 12 days after full-thickness incisions. A monospecific rabbit polyclonal antibody...

journal_title：Connective tissue research

authors： Porras-Reyes BH,Blair HC,Jeffrey JJ,Mustoe TA

更新日期：1991-01-01 00:00:00

abstract：:The meniscal cartilages in the knee function to improve congruity of the medial and lateral femoro-tibial joints and play critical roles in load distribution and joint stability. Meniscal tears of various configurations are one of the most common conditions of the knee and are associated with an increased risk of deve...

journal_title：Connective tissue research

authors： Melrose J,Fuller ES,Little CB

更新日期：2017-01-01 00:00:00

abstract：:Short term cultures were carried out with chondrocytes and tissue fragments from fetal guinea pig epiphyseal cartilage. Proteoglycans were isolated from these cultures and their properties were compared with those of proteoglycans from adult hyaline cartilage. It was concluded that the proteoglycans synthesized in cul...

journal_title：Connective tissue research

authors： Madsen K,Lohmander S,Moskalewski S,Hinek A

更新日期：1978-01-01 00:00:00

abstract：:Small proteoglycans were dissociatively extracted from normal human thoracic aorta with 4 M guanidine hydrochloride containing protease inhibitors, and purified by Sepharose CL-4B chromatography, dissociative cesium chloride density gradient centrifugation, and diethylaminoethyl cellulose chromatography. The intact pr...

journal_title：Connective tissue research

authors： Register TC,Wagner WD

更新日期：1990-01-01 00:00:00

abstract：:The purpose of this study was to investigate overall degradative changes occurring to enamel matrix proteins in small, freeze-dried pieces of rat incisor enamel homogenized and incubated directly for 0-48 hours in a synthetic enamel fluid solution (165 mM total ionic strength with 0.153 mM calcium chloride) versus oth...

journal_title：Connective tissue research

authors： Smith CE,Chen WY

更新日期：1998-01-01 00:00:00

abstract：:We have previously shown in a transgenic mouse line, in which 5.2 kb of the elastin promoter was linked to the reporter enzyme chloramphenicol acetyltransferase (CAT), that the highest levels of expression were found in embryonic lungs and aorta, while lower levels were detected in other elastin-containing tissues. Fu...

journal_title：Connective tissue research

authors： Lakkakorpi J,Li K,Decker S,Korkeela E,Piddington R,Abrams W,Bashir M,Uitto J,Rosenbloom J

更新日期：1999-01-01 00:00:00

abstract：:The in-vitro fluoride treatment technique has been introduced to investigate the composite behavior of bone tissue. Bone tissue with different mechanical properties can be obtained by varying the concentration, pH and immersion time in fluoride ion solutions. The chemical and physical changes in intact pieces of bone ...

journal_title：Connective tissue research

authors： Kotha SP,DePaula CA,Koike K,Pan Y,Ohno M,Abjornson C,Rangarajan S,Guzelsu N

更新日期：2002-01-01 00:00:00

abstract：:Growth and differentiation factor-5 (GDF-5) is known to induce tendon tissue and stimulate tendon healing. The hypothesis was that adenoviral GDF-5 transfer leads to transitory transgene expression and improves Achilles tendon healing. In vitro experiments were first performed with rat tenocytes. Transgene expression ...

journal_title：Connective tissue research

authors： Rickert M,Wang H,Wieloch P,Lorenz H,Steck E,Sabo D,Richter W

更新日期：2005-01-01 00:00:00

abstract：:Eruption requires synchrony of the tooth with the surrounding tissues, particularly the bone. One important step during eruption is remodelling of the alveolar bone at the base of the tooth and along the roots. Expression of BMP6 was reported to be increased in the basal half of the dental follicle prior to eruption a...

journal_title：Connective tissue research

authors： Oralová V,Chlastáková I,Radlanski RJ,Matalová E

更新日期：2014-10-01 00:00:00

abstract：:X-Ray diffraction and scanning electron microscopy show that collagen fibrils tend to be oriented parallel to the surface of the vertebral end plates in pig, rat and man. It is suggested that this orientation allows the end plate to withstand the pressure exerted on it by the nucleus pulposus. Scanning electron micros...

journal_title：Connective tissue research

authors： Aspden RM,Hickey DS,Hukins DW

更新日期：1981-01-01 00:00:00

abstract：:The biological effects of isolated soluble dentin extracellular matrix components on the induction of reparative dentinogenesis in exposed cavities in ferret canine teeth have been shown to be blocked by immobilizing the extracellular matrix components on nitrocellulose or Millipore membranes during implantation. This...

journal_title：Connective tissue research

authors： Smith AJ,Tobias RS,Cassidy N,Bégue-Kirn C,Ruch JV,Lesot H

更新日期：1995-01-01 00:00:00

abstract：:Alveolar mucosa and attached gingiva are two continuous but functionally distinct connective tissues covering alveolar bone of the jaw. In this study, the major matrix component of these tissues, collagen, was biochemically characterized and compared. The tissues were obtained from mature pigs and analyzed for collage...

journal_title：Connective tissue research

authors： Katafuchi M,Matsuura T,Atsawasuwan P,Sato H,Yamauchi M

更新日期：2007-01-01 00:00:00

abstract：:Part of the hyaluronic acid (HA) synthesized in peripheral tissues enters the blood circulation through the lymph. It is rapidly taken up by the endothelial cells in the liver (half-life in blood is 2.5-5.5 minutes) and degraded. Pure primary cultures of liver endothelial cells were obtained by a newly developed techn...

journal_title：Connective tissue research

authors： Laurent TC,Dahl IM,Dahl LB,Engström-Laurent A,Eriksson S,Fraser JR,Granath KA,Laurent C,Laurent UB,Lilja K

更新日期：1986-01-01 00:00:00

abstract：:Keratocan is an extracellular matrix protein that belongs to the small leucine-rich proteoglycan family that also includes lumican, biglycan, decorin, mimecan, and fibromodulin. Members of this family are known to play a role in regulating cellular processes such as proliferation and modulation of osteoprogenitor line...

journal_title：Connective tissue research

authors： Igwe JC,Gao Q,Kizivat T,Kao WW,Kalajzic I

更新日期：2011-10-01 00:00:00

abstract：:Purpose: In our previous study, we demonstrated that hyaluronan induces odontoblastic differentiation of dental pulp stem cells via interactions with CD44. However, it remains unclear whether CD44 expression by dental pulp stem cells is required for odontoblastic differentiation. Methods: We searched for a compound ot...

journal_title：Connective tissue research

authors： Kajiura K,Umemura N,Ohkoshi E,Ohta T,Kondoh N,Kawano S

更新日期：2021-01-12 00:00:00

abstract：:The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved...

journal_title：Connective tissue research

authors： Møller R,Serup J,Ammitzbøll T

更新日期：1985-01-01 00:00:00

abstract：:The interaction of elastin and microfibrils in elastogenesis in vitro was investigated with electron microscopy and immunohistochemistry. Fetal human pulmonary fibroblasts were cultured with or without beta-aminopropionitrile (BAPN). One week after seeding, the extracellular microfibrils were loosely arranged without ...

journal_title：Connective tissue research

authors： Fukuda Y,Nakazawa N,Yamanaka N

更新日期：1993-01-01 00:00:00

abstract：:The molecular substructure of human articular cartilage has been difficult to study because of its complex composition and high degree of hydration. Using newly available small-angle X-ray diffraction (SAX) instrumentation that allows very short exposure times (0.1 to 10 sec), we have obtained spatially resolved infor...

journal_title：Connective tissue research

authors： Mollenhauer J,Aurich M,Muehleman C,Khelashvilli G,Irving TC

更新日期：2003-01-01 00:00:00