In vivo expression of classic PKC isoforms in the rat dental follicle as related to tooth eruption.

abstract：:Changes in the structure and organization of collagen fibrils were recently described in the skin of aspartylglycosaminuria patients. The skin of the patients contained a normal amount and distribution of glycosaminoglycans, but the dermatan sulfate of aspartylglycosaminuria skin was more sensitive to chondroitinase A...

journal_title：Connective tissue research

authors： Näntö-Salonen K,Larjava H,Säämanen AM,Heino J,Penttinen R,Pelliniemi LJ,Tammi M

更新日期：1987-01-01 00:00:00

abstract：:The purpose of this study was to examine the hypoxic and inflammatory conditions after immobilization in the joint capsule of rat knees. The unilateral knee joints of adult male rats were immobilized with an internal fixator (Im group) for 1 day, 3 days, and 1, 2, 4, 8, and 16 weeks. Sham-operated animals had holes dr...

journal_title：Connective tissue research

authors： Yabe Y,Hagiwara Y,Suda H,Ando A,Onoda Y,Tsuchiya M,Hatori K,Itoi E

更新日期：2013-01-01 00:00:00

abstract：:The total and individual glycosaminoglycan (GAG) content at various stages of the Dupuytren disease process and in samples of normal palmar connective tissue (palmar dermis, palmar fascia and digital flexor tendon) from the hands of uninvolved age-matched controls have been assayed and compared. Morphological comparis...

journal_title：Connective tissue research

authors： Flint MH,Gillard GC,Reilly HC

更新日期：1982-01-01 00:00:00

abstract：:The menisci are intricately organized structures that perform many tasks in the knee. We review their structure and function and introduce new data about their tibial and femoral surfaces. As the femur and tibia approach each other when the knee is bearing load, circumferential tension develops in the menisci, enablin...

journal_title：Connective tissue research

authors： Andrews SHJ,Adesida AB,Abusara Z,Shrive NG

更新日期：2017-01-01 00:00:00

abstract：:Muscle-derived cells can differentiate into chondrogenic cells. In our present study, we investigated the pattern of expression of Sox9, a transcription factor known to play a key role in chondrogenesis, in a rat myoblastic cell line, L6. In addition, we evaluated expression of type II collagen and myogenic regulatory...

journal_title：Connective tissue research

authors： Matsushita T,Matsui N,Fujioka H,Kubo S,Kuroda R,Kurosaka M,Yoshiya S

更新日期：2004-01-01 00:00:00

abstract：:Glycosaminoglycan synthesis by cells cultured from nodule or band tissues of patients with Dupuytren's disease was compared with that of skin fibroblasts cultured from uninvolved areas of the palm. No differences were observed in culture which could account either for the abnormal glycosaminoglycan content or the incr...

journal_title：Connective tissue research

authors： Slack C,Flint MH,Thompson BM

更新日期：1982-01-01 00:00:00

abstract：:To investigate the source of bone brittleness in the disease osteogenesis imperfecta (OI), biomechanical properties have been measured in the femurs from a homozygous (oim/oim) mutant mouse model of OI, its heterozygous littermates, and wild-type animals. The novel technique of ultrasound critical-angle reflectometry ...

journal_title：Connective tissue research

authors： Mehta SS,Antich PP,Landis WJ

更新日期：1999-01-01 00:00:00

abstract：:Many organisms from a wide variety of taxa produce amorphous calcium carbonate (ACC), despite the fact that it is inherently unstable and relatively soluble in its pure state. These properties also make it difficult to detect and characterize ACC. Raman spectroscopy is a particularly useful method for investigating AC...

journal_title：Connective tissue research

authors： Weiner S,Levi-Kalisman Y,Raz S,Addadi L

更新日期：2003-01-01 00:00:00

abstract：:Degeneration of the intervertebral discs, a natural progression of the aging process, is strongly implicated as a cause of low back pain. Aggrecan is the major structural proteoglycan in the extracellular matrix of the intervertebral disc. It is large, possessing numerous glycosaminoglycan chains and the ability to fo...

journal_title：Connective tissue research

authors： Wei Q,Zhang X,Zhou C,Ren Q,Zhang Y

更新日期：2019-05-01 00:00:00

abstract：:Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal li...

journal_title：Connective tissue research

authors： Cho H,Tarafder S,Fogge M,Kao K,Lee CH

更新日期：2016-11-01 00:00:00

abstract：:Parietal yolk sacs isolated from 14.5-day rat embryos and incubated in vitro with either [14C]proline, [3H]mannose or 3H-labeled amino acid mixture synthesized and secreted basement membrane collagenous and noncollagenous glycoprotein components with relative molecular weights of 350,000 (350K), 220,000 (220K), 185,00...

journal_title：Connective tissue research

authors： Clark CC,Kefalides NA

更新日期：1982-01-01 00:00:00

abstract：:Collagen type I fiber-based scaffolds for anterior cruciate ligament (ACL) replacement were evaluated for their mechanical properties and their ability to promote cellular proliferation. Prior to scaffold formation, two crosslinking methods were investigated on individual reconstituted collagen type I fibers, ultravio...

journal_title：Connective tissue research

authors： Walters VI,Kwansa AL,Freeman JW

更新日期：2012-01-01 00:00:00

abstract：:Tubulointerstitial nephritis antigen (TIN-ag) is a recently described basement membrane component reactive with autoantibodies in some forms of autoimmune mediated tubulointerstitial nephritis. Immunofluorescence studies using polyclonal and monoclonal antibodies have indicated a restrictive tissue distribution for TI...

journal_title：Connective tissue research

authors： Nelson TR,Butkowski RJ,Michael AF,Charonis AS

更新日期：1997-01-01 00:00:00

abstract：:Ligaments have limited regenerative potential and as a consequence, repair is protracted and results in a mechanically inferior tissue more scar-like than native ligament. We previously reported that a single injection of interleukin-1 receptor antagonist (IL-1Ra) delivered at the time of injury, decreased the number ...

journal_title：Connective tissue research

authors： Chamberlain CS,Leiferman EM,Frisch KE,Duenwald-Kuehl SE,Brickson SL,Murphy WL,Baer GS,Vanderby R

更新日期：2014-06-01 00:00:00

abstract：:Bone sialoprotein (BSP) and osteopontin (OPN) are two extracellular bone matrix proteins that have the ability to modulate the growth of hydroxyapatite in vitro. Studies of BSP/OPN hydroxyapatite interactions in the past have been directed toward the identification of essential structural elements that allow these two...

journal_title：Connective tissue research

authors： Stubbs JT 3rd

更新日期：1996-01-01 00:00:00

abstract：:Solutions of type I acid soluble collagen were studied in light and electron microscopy at concentrations over 40 mg/ml. Banded patterns spontaneously emerge in samples observed between crossed polars between slide and coverslip. The textures are interpreted as precholesteric, appearing at the transition between the i...

journal_title：Connective tissue research

authors： Giraud-Guille MM,Besseau L

更新日期：1998-01-01 00:00:00

abstract：:To elucidate the mechanism of accumulation and fragmentation of hyaluronic acid (HA) under inflammatory conditions, we investigated the effect of proinflammatory cytokines on hyaluronic acid synthetase (HAS) mRNA expression using cultured rabbit synovial membrane cells. HASs mRNA levels were determined by real-time PC...

journal_title：Connective tissue research

authors： Tanimoto K,Ohno S,Fujimoto K,Honda K,Ijuin C,Tanaka N,Doi T,Nakahara M,Tanne K

更新日期：2001-01-01 00:00:00

abstract：:Aggrecan is the prominent proteoglycan in cartilage and is modified with approximately 100 chondroitin sulfate (CS) chains through a tetrasaccharide linkage structure. In osteoarthritis (OA), the viscoelastic properties of cartilage are compromised on both the quantity and integrity of aggrecan core protein expressed ...

journal_title：Connective tissue research

authors： Frankenberger C,Borgia JA,Edirisinghe PD,Oegema TR

更新日期：2013-01-01 00:00:00

abstract：:Depolymerization of Ch-4-S, Ch-6-S, HA and HP was observed by gel filtration after treatment with 2-10 N NaOH or Ba(OH)2 in the presence of NaBH4 at 80-83 degrees for 1-5 hr. Depolymerized products were isolated after these treatments. 4-Deoxy-alpha-L-threo-4-enohexopyranosyluronic acid residue as the nonreducing end ...

journal_title：Connective tissue research

authors： Hirano S,Ishigami M,Koga Y

更新日期：1975-01-01 00:00:00

abstract：:The connective tissue protein elastin is largely responsible for maintaining the elasticity of major blood vessels and lung tissue. Comparatively few studies have been made of the immunologic properties of elastin because of its high degree of insolubility and because of its apparent limited capacity to elicit precipi...

journal_title：Connective tissue research

authors： Kucich U,Christner P,Rosenbloom J,Weinbaum G

更新日期：1981-01-01 00:00:00

abstract：:For many years we have investigated the earliest crystal formations of different developing hard tissues (matrix vesicle, bone, dentine, enamel, etc.) by different electron microscopic measurements. It was observed that primarily Ca-phosphate (apatite) "chains," composed of nanometer sized particles (dots, islands), e...

journal_title：Connective tissue research

authors： Höhling HJ,Arnold S,Barckhaus RH,Plate U,Wiesmann HP

更新日期：1995-01-01 00:00:00

abstract：:Raman spectra have been determined for hyaluronan, chondroitin-4-sulfate, chondroitin-6-sulfate, aggrecan monomers and aggregates. The nature of the saccharides and the pattern of sulfation can be discerned. There were only small spectral changes with pH and ionic composition. Differences between hydroxyl vibrations, ...

journal_title：Connective tissue research

authors： Ellis R,Green E,Winlove CP

更新日期：2009-01-01 00:00:00

abstract：:Sea urchin's teeth from four families of order Echinoida and from orders Temnopleuroida, Arbacioida and Cidaroida were studied with synchrotron X-ray diffraction. The high and very high Mg calcite phases of the teeth, i.e. the first and second stage mineral constituents, respectively, have the same crystallographic or...

journal_title：Connective tissue research

authors： Stock SR,Ignatiev K,Lee PL,Almer JD

更新日期：2014-08-01 00:00:00

abstract：:The fibrous collagens form the structural basis of all mammalian connective tissues, including the vasculature, dermis, bones, tendons, cartilage, and those tissues that support organs such as the heart, kidneys, liver, and lungs. The helical structure of collagen has been extensively studied but in addition to its he...

journal_title：Connective tissue research

authors： Orgel JP,San Antonio JD,Antipova O

更新日期：2011-02-01 00:00:00

abstract：:The binding of highly purified bovine aortic lysyl oxidase to native fibrils of type I collagen has been measured by assay of unbound lysyl oxidase activity in the supernatants of enzyme-collagen mixtures after centrifugation. The apparent binding affinity of lysyl oxidase for native fibrils is quite similar to that f...

journal_title：Connective tissue research

authors： Cronlund AL,Smith BD,Kagan HM

更新日期：1985-01-01 00:00:00

abstract：:Human skin fibroblasts cultured with 4-methylumbelliferone (MU), a hyaluronan synthesis inhibitor, produce a hyaluronan-deficient extracellular matrix (See [9]). Our present study investigated the effects of MU on proteoglycan, which is the other main component of the extracellular matrix, and interacts with hyalurona...

journal_title：Connective tissue research

authors： Funahashi M,Nakamura T,Kakizaki I,Mizunuma H,Endo M

更新日期：2009-01-01 00:00:00

abstract：:To study the glycosylation of glomerular basement membrane collagen (GBMC) in diabetes, kidneys were obtained at autopsy from 5 patients with insulin-requiring diabetes of long duration and diabetic complications, and from 5 control subjects. Glomeruli were prepared by sieving and collagen was isolated by limited peps...

journal_title：Connective tissue research

authors： Uitto J,Perejda AJ,Grant GA,Rowold EA,Kilo C,Williamson JR

更新日期：1982-01-01 00:00:00

abstract：:This study examines the similarities and differences in the noncollagenous domain (NC1) of type IV collagen from human glomerular basement membrane (hGBM), alveolar basement membrane (hABM), and placenta (hPBM). Following collagenase digestion, NC1 domain was isolated on Bio-Gel A-0.5m or by cation exchange chromatogr...

journal_title：Connective tissue research

authors： Shen GQ,Butkowski R,Cheng T,Wieslander J,Katz A,Cass J,Fish AJ

更新日期：1990-01-01 00:00:00

abstract：:Although intervertebral disc (IVD) degeneration is one of most common causes of morbidity, its etiology remains unclear. In healthy discs, the rates of synthesis and breakdown of the extracelluar matrix (ECM) are in equilibrium because of intricate regulation by growth factors and catabolic cytokines. Important among ...

journal_title：Connective tissue research

authors： Cho H,Lee S,Park SH,Huang J,Hasty KA,Kim SJ

更新日期：2013-01-01 00:00:00

abstract：:To explore crucial early molecular events involved in contact healing of the intrasynovial flexor tendon, integrin expression was evaluated at the transcriptional and post-transcriptional levels during the first two weeks following injury, repair and controlled passive motion in a canine model. Specifically, immunohis...

journal_title：Connective tissue research

authors： Harwood FL,Monosov AZ,Goomer RS,Gelberman RH,Winters SC,Silva MJ,Amiel D

更新日期：1998-01-01 00:00:00