Current concepts on structure-function relationships in the menisci.

abstract：:The critical remembrance of my research activity displays aspects of inconsequence and mental rigidity. Particular probative examples are called to mind. Unpublished observations concerning immortalized dental cells are summarized. As a consequence, if I could start again, I would improve several aspects of my behavio...

journal_title：Connective tissue research

authors： Ruch JV

更新日期：2002-01-01 00:00:00

abstract：:We previously reported that circulating peripheral blood-borne cells (PBCs) contribute to early-phase meniscal reparative change. Because macrophages and myofibroblasts are important contributors of tissue regeneration, we examined their origin and distribution in the reparative meniscus. Reparative menisci were evalu...

journal_title：Connective tissue research

authors： Terai S,Hashimoto Y,Orita K,Yamasaki S,Takigami J,Shinkuma T,Teraoka T,Nishida Y,Takahashi M,Nakamura H

更新日期：2017-11-01 00:00:00

abstract：:Purpose: In our previous study, we demonstrated that hyaluronan induces odontoblastic differentiation of dental pulp stem cells via interactions with CD44. However, it remains unclear whether CD44 expression by dental pulp stem cells is required for odontoblastic differentiation. Methods: We searched for a compound ot...

journal_title：Connective tissue research

authors： Kajiura K,Umemura N,Ohkoshi E,Ohta T,Kondoh N,Kawano S

更新日期：2021-01-12 00:00:00

abstract：:Large joint arthrofibrosis and scarring, involving the shoulder, elbow, hip, and knee, can result in the loss of function and immobility. The pathway of joint contracture formation is still being elucidated and is due to aberrations in collagen synthesis and misorientation of collagen fibrils. Novel antibodies are bei...

journal_title：Connective tissue research

authors： Chen AF,Lee YS,Seidl AJ,Abboud JA

更新日期：2019-01-01 00:00:00

abstract：:To extend previous studies on the apparent acceleration of collagen aging in diabetes mellitus, dura collagen from human adults of different ages, with and without diabetes, was processed to yield soluble and insoluble fractions. Insoluble fractions were cleaved by cyanogen bromide. Release of peptides from insoluble ...

journal_title：Connective tissue research

authors： Kohn RR

更新日期：1983-01-01 00:00:00

abstract：:Aggrecan is the prominent proteoglycan in cartilage and is modified with approximately 100 chondroitin sulfate (CS) chains through a tetrasaccharide linkage structure. In osteoarthritis (OA), the viscoelastic properties of cartilage are compromised on both the quantity and integrity of aggrecan core protein expressed ...

journal_title：Connective tissue research

authors： Frankenberger C,Borgia JA,Edirisinghe PD,Oegema TR

更新日期：2013-01-01 00:00:00

abstract：:Transforming growth factor beta (TGF-beta) is a ubiquitous regulator of cellular growth and differentiation. The present study investigated the effects of TGF-beta on chick growth plate chondrocyte proliferation, matrix synthesis, and alkaline phosphatase activity in short term cultures. TGF-beta markedly stimulated D...

journal_title：Connective tissue research

authors： Rosier RN,O'Keefe RJ,Crabb ID,Puzas JE

更新日期：1989-01-01 00:00:00

abstract：:Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxypro...

journal_title：Connective tissue research

authors： Heeger P,Rosenbloom J

更新日期：1980-01-01 00:00:00

abstract：:Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal li...

journal_title：Connective tissue research

authors： Cho H,Tarafder S,Fogge M,Kao K,Lee CH

更新日期：2016-11-01 00:00:00

abstract：:Objective: Aseptic loosening is a major problem in total joint replacement. Implant wear debris provokes a foreign body host response and activates cells to produce a variety of mediators and ROS, leading to periprosthetic osteolysis. Elevated ROS levels can harm proteasome function. Proteasome inhibitors have been re...

journal_title：Connective tissue research

authors： Niarakis A,Giannopoulou E,Syggelos SA,Panagiotopoulos E

更新日期：2019-11-01 00:00:00

abstract：:Cumulative damage to long-lived connective tissue proteins play a key role in the development of age-related human diseases such as cardiovascular stiffening and age-related macular degeneration. The processes that result in the accumulation of increasingly insoluble, undigestible damaged collagen are only partially k...

journal_title：Connective tissue research

authors： Paik DC,Saito LY,Sugirtharaj DD,Holmes JW

更新日期：2006-01-01 00:00:00

abstract：:This study evaluated the effect of short bouts of stretching on the soleus muscle after immobilization, by measuring the birefringence of the intramuscular connective tissue (ICT) and the muscle fiber area. Thirty rats were divided into five groups: the left soleus was immobilized in the shortened position; after immo...

journal_title：Connective tissue research

authors： Coutinho EL,DeLuca C,Salvini TF,Vidal BC

更新日期：2006-01-01 00:00:00

abstract：:Collagen type I fiber-based scaffolds for anterior cruciate ligament (ACL) replacement were evaluated for their mechanical properties and their ability to promote cellular proliferation. Prior to scaffold formation, two crosslinking methods were investigated on individual reconstituted collagen type I fibers, ultravio...

journal_title：Connective tissue research

authors： Walters VI,Kwansa AL,Freeman JW

更新日期：2012-01-01 00:00:00

abstract：:Alveolar mucosa and attached gingiva are two continuous but functionally distinct connective tissues covering alveolar bone of the jaw. In this study, the major matrix component of these tissues, collagen, was biochemically characterized and compared. The tissues were obtained from mature pigs and analyzed for collage...

journal_title：Connective tissue research

authors： Katafuchi M,Matsuura T,Atsawasuwan P,Sato H,Yamauchi M

更新日期：2007-01-01 00:00:00

abstract：:An agarose gel matrix was utilized to grow chondrocytes from human donors of various ages in cell culture. The chondrocytes produced the pericellular matrix characteristic for such cells and synthesized collagen type II as well as glyco-saminoglycans. The latter exhibit the typical distribution pattern of the respecti...

journal_title：Connective tissue research

authors： Delbrück A,Dresow B,Gurr E,Reale E,Schröder H

更新日期：1986-01-01 00:00:00

abstract：:The diameter of collagen fibrils has been measured in electron micrographs of the tunica media and adventitia of the common carotid artery of 14 rats (19,262 counts). The fibrils of the media were measured in each of its three interlamellar spaces. The mean fibril diameters in the innermost space and the middle space ...

journal_title：Connective tissue research

authors： Buck RC

更新日期：1987-01-01 00:00:00

abstract：:The turnover of proteoglycans in bovine articular cartilage was determined in explant cultures, maintained at 32 degrees C or 37 degrees C. Both the rate of proteoglycan synthesis and the release of newly synthesized proteoglycans were decreased in cultures incubated at 32 degrees C compared to 37 degrees C. At both t...

journal_title：Connective tissue research

authors： Brand HS,De Koning MH,van Kampen GP,Van der Korst JK

更新日期：1991-01-01 00:00:00

abstract：:Bovine articular chondrocytes cultured in agarose gel comprise a heterogeneous population when judged by morphological and histochemical criteria. The purpose of the present experiments was to compare, under the same conditions of culture, sub-populations of chondrocytes derived from different depths of articular cart...

journal_title：Connective tissue research

authors： Aydelotte MB,Kuettner KE

更新日期：1988-01-01 00:00:00

abstract：:Syndecan-4 is emerging as an important player in cell interaction with the extracellular environment and has been shown to be involved in the progression of intervertebral disc degeneration. However, the mechanism of syndecan-4 regulation by TNF-α and the role of TGF-β1 in regulating syndecan-4 expression remain poorl...

journal_title：Connective tissue research

authors： Yang H,Liu H,Li X,Pan H,Li Z,Wang J,Zheng Z

更新日期：2015-01-01 00:00:00

abstract：:To investigate the source of bone brittleness in the disease osteogenesis imperfecta (OI), biomechanical properties have been measured in the femurs from a homozygous (oim/oim) mutant mouse model of OI, its heterozygous littermates, and wild-type animals. The novel technique of ultrasound critical-angle reflectometry ...

journal_title：Connective tissue research

authors： Mehta SS,Antich PP,Landis WJ

更新日期：1999-01-01 00:00:00

abstract：:Genetic diseases affecting tooth structure have been classified by the tissue affected enamel versus dentin, and their pattern of inheritance autosomal dominant, autosomal recessive, or X-linked. Advances in molecular genetics and the Human Genome Project have provided substantial progress regarding the identification...

journal_title：Connective tissue research

authors： MacDougall M

更新日期：2003-01-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are members of the Metzincin family of proteases responsible for degrading the extracellular matrix (ECM). In early studies, MMP degradation of the sub-epithelial basement membrane was thought to be tumor cell autonomous and contribute to the invasive behavior of malignant cells. It is...

journal_title：Connective tissue research

authors： Stetler-Stevenson WG,Gavil NV

更新日期：2014-01-01 00:00:00

abstract：:Muscle-derived cells can differentiate into chondrogenic cells. In our present study, we investigated the pattern of expression of Sox9, a transcription factor known to play a key role in chondrogenesis, in a rat myoblastic cell line, L6. In addition, we evaluated expression of type II collagen and myogenic regulatory...

journal_title：Connective tissue research

authors： Matsushita T,Matsui N,Fujioka H,Kubo S,Kuroda R,Kurosaka M,Yoshiya S

更新日期：2004-01-01 00:00:00

abstract：:Heparin treated and aldehyde crosslinked rat aorta segments were implanted in infrarenal aorta of homologous rats. One year following aortic replacement, the subendothelial scar and the prosthetic remnants were excised. The scar and the host intima-media were incubated with 3H-valine for 4 h and extracted with 5 M gua...

journal_title：Connective tissue research

authors： Moczar M,Bessou JP,Loisance D

更新日期：1983-01-01 00:00:00

abstract：:These studies examined the effects of heat-inactivated horse serum, insulin, triiodothyronine (T3), and thyroxine (T4), individually and in combination, on collagen and proteoglycan synthesis by primary cell cultures of articular chondrocytes from immature male rabbits. Insulin concentrations of 25 to 100 ng/ml (4.4 t...

journal_title：Connective tissue research

authors： Glade MJ,Kanwar YS,Stern PH

更新日期：1994-01-01 00:00:00

abstract：:Volume and morphology of chondrocytes in osteoarthritic human hip joint articular cartilage were characterized, and their relationship to tissue structure and function was determined. Human osteochondral articular cartilage samples (n=16) were obtained from the femoral heads of nine patients undergoing total hip arthr...

journal_title：Connective tissue research

authors： Huttu MR,Puhakka J,Mäkelä JT,Takakubo Y,Tiitu V,Saarakkala S,Konttinen YT,Kiviranta I,Korhonen RK

更新日期：2014-08-01 00:00:00

abstract：:Laminin promotes adhesion of various cell types via multiple interactions with cell surface components. We have used a laminin domain involved in adhesion of melanoma cells, peptide F9 (Charonis et al., J. Cell Biol. 107:1253 [( 1988]), to examine its specific interaction with cell surface components. Cells were surfa...

journal_title：Connective tissue research

authors： Koliakos GG,Tsilibary EC,Charonis AS

更新日期：1991-01-01 00:00:00

abstract：:A theoretical expression has been derived for the mean collagen fibril length in tendon based on the assumption that collagen fibrils originate in cell surface invaginations and terminate either at some remote cell surface or another collagen fibril bundle. The expression thus determined requires knowledge of the effe...

journal_title：Connective tissue research

authors： Craig AS,Birtles MJ,Conway JF,Parry DA

更新日期：1989-01-01 00:00:00

abstract：:To study the glycoproteins and transglutaminase substrates involved in healing, wounds were made in the skin of anesthetized rats with a biopsy punch. Explants made 1-5 days later were incubated with [3H]-labelled putrescine, fucose or proline. As compared with unwounded skin there was an increased incorporation of la...

journal_title：Connective tissue research

authors： Bowness JM,Henteleff H,Dolynchuk KN

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:Our previous study showed that partial-thickness articular cartilage defects (PTCDs) created in immature rats spontaneously healed to resemble normal hyaline cartilage, but that of mature rats did not. To identify molecules involved in the spontaneous cartilage repair observed in this model, gene expression was...

journal_title：Connective tissue research

authors： Ikegawa N,Sasho T,Yamaguchi S,Saito M,Akagi R,Muramatsu Y,Akatsu Y,Fukawa T,Nakagawa K,Nakajima A,Suzuki T,Takahashi K

更新日期：2016-05-01 00:00:00