Expression of transcription factor Sox9 in rat L6 myoblastic cells.

abstract：:During cloning of the rat incisor phosphophoryn gene, several clones were identified with a PP antibody. One of the clones (2PP) was shown to encode a PP denoted as dentin matrix protein 2, DMP2. We have now sequenced another clone, which appears to be bifunctional, or at minimum, has two distinct domains. The 5' regi...

journal_title：Connective tissue research

authors： George A,Srinivasan RThotakura SR,Liu K,Veis A

更新日期：1999-01-01 00:00:00

abstract：:A theoretical expression has been derived for the mean collagen fibril length in tendon based on the assumption that collagen fibrils originate in cell surface invaginations and terminate either at some remote cell surface or another collagen fibril bundle. The expression thus determined requires knowledge of the effe...

journal_title：Connective tissue research

authors： Craig AS,Birtles MJ,Conway JF,Parry DA

更新日期：1989-01-01 00:00:00

abstract：AIM OF THE STUDY:To further elucidate the pathogenesis of systemic sclerosis (SSc) an experimental avian model was used. The University of California at Davis line 200 (UCD-200) chickens spontaneously develop a SSc-like disease that has most features of human SSc with vascular effects, inflammation, autoimmunity, and f...

journal_title：Connective tissue research

authors： Kerje S,Hellman U,Do L,Larsson G,Kämpe O,Engström-Laurent A,Lindqvist U

更新日期：2016-09-01 00:00:00

abstract：: Purpose/Aim of the study mice are the most often used pre-clinical lab models for studying the pathologies of bone mineralization. However, recent evidence suggests that two of the most often used mice strains (C57BL/6J and CD-1) might show differences in the bone minerali...

journal_title：Connective tissue research

authors： Fayolle C,Labrune M,Berteau JP

更新日期：2020-09-01 00:00:00

abstract：AIM OF THE STUDY:Tendons are exposed to mechanical stress constantly during movements and thus they are frequently subjected to injuries. Rotator cuff tears are common musculoskeletal disorders, mainly involving the supraspinatus tendon. The characterization of the tenocytes derived from this tendon and the comparison ...

journal_title：Connective tissue research

authors： Viganò M,Lugano G,Orfei CP,Menon A,Ragni E,Colombini A,de Luca P,Talò G,Randelli PS,de Girolamo L

更新日期：2020-09-14 00:00:00

abstract：:Positive effects on the tensile characteristics of swine digital extensors were found following twelve months of exercise training. Compared to sedentary controls, the tendons from the exercised animals became stronger as a material and exhibited hypertrophy. These biomechanical results were supported by biochemical a...

journal_title：Connective tissue research

authors： Woo SL,Ritter MA,Amiel D,Sanders TM,Gomez MA,Kuei SC,Garfin SR,Akeson WH

更新日期：1980-01-01 00:00:00

abstract：:DNA synthesis in rat and rabbit polyvinyl sponge induced granulation tissue has been studied using thymidine (methyl-3H). Synthesis was determined by measurement of thymidine incorporation into cold trichloroacetic acid insoluble material and by autoradiography. Granulation tissue was removed and immediately incubated...

journal_title：Connective tissue research

authors： Wiener SL,Urivetzky M,Isenberg HD,Havier R,Wiener R,Belenko M,Heydu E,Meilman E

更新日期：1976-01-01 00:00:00

abstract：:EMDOGAIN is derived from porcine developing enamel matrix and has been shown to facilitate regeneration of the periodontium, although its mechanism of action is unknown. The aim of the present study was to identify enamel matrix proteins and proteolytic enzymes present in EMDOGAIN and compare them with those extracted...

journal_title：Connective tissue research

authors： Maycock J,Wood SR,Brookes SJ,Shore RC,Robinson C,Kirkham J

更新日期：2002-01-01 00:00:00

abstract：:Of more than 2 million segmental bone defects repaired annually with bone autografts and allografts, 15-40% fail. Improving healing rates may be approached with tissue engineering and use of periosteum overlying an allograft. The present study documents gene expression in human periosteum-allograft constructs compared...

journal_title：Connective tissue research

authors： Kemppainen J,Yu Q,Alexander J,Jacquet R,Scharschmidt T,Landis W

更新日期：2014-08-01 00:00:00

abstract：:The use of electron microscopic observations to characterize the state of aggregation of collagen molecules in solution has been examined from the point of view that the observed structures must be compatible with the physical chemical properties of the solution. The common procedure of addition of droplets of a colla...

journal_title：Connective tissue research

authors： Schwartz D,Veis A

更新日期：1978-01-01 00:00:00

abstract：:To explore crucial early molecular events involved in contact healing of the intrasynovial flexor tendon, integrin expression was evaluated at the transcriptional and post-transcriptional levels during the first two weeks following injury, repair and controlled passive motion in a canine model. Specifically, immunohis...

journal_title：Connective tissue research

authors： Harwood FL,Monosov AZ,Goomer RS,Gelberman RH,Winters SC,Silva MJ,Amiel D

更新日期：1998-01-01 00:00:00

abstract：:Proteoglycans extracted from articular cartilage of large joints of humans aged 4, 11, 70 and 75, were fractionated on associative density gradients. The top fraction (A3) was purified by ion-exchange chromatography and subsequent gel filtration on Sepharose CL 4B in 4 M GuCl, 0.5% Triton x 100. Proteoglycans from you...

journal_title：Connective tissue research

authors： Stanescu V,Chaminade F,Muriel MP

更新日期：1988-01-01 00:00:00

abstract：:The purpose of this study was to examine the hypoxic and inflammatory conditions after immobilization in the joint capsule of rat knees. The unilateral knee joints of adult male rats were immobilized with an internal fixator (Im group) for 1 day, 3 days, and 1, 2, 4, 8, and 16 weeks. Sham-operated animals had holes dr...

journal_title：Connective tissue research

authors： Yabe Y,Hagiwara Y,Suda H,Ando A,Onoda Y,Tsuchiya M,Hatori K,Itoi E

更新日期：2013-01-01 00:00:00

abstract：:This investigation is devoted to the study of the viscoelastic behavior of human abdominal fascia from the umbilical region. Seventeen samples 10 mm wide and up to 70 mm long were cut along the primary fiber direction (group FL) or perpendicular to it (group FT) and subjected to relaxation tests. The viscoelastic resp...

journal_title：Connective tissue research

authors： Kirilova M

更新日期：2012-01-01 00:00:00

abstract：:The in-vitro fluoride treatment technique has been introduced to investigate the composite behavior of bone tissue. Bone tissue with different mechanical properties can be obtained by varying the concentration, pH and immersion time in fluoride ion solutions. The chemical and physical changes in intact pieces of bone ...

journal_title：Connective tissue research

authors： Kotha SP,DePaula CA,Koike K,Pan Y,Ohno M,Abjornson C,Rangarajan S,Guzelsu N

更新日期：2002-01-01 00:00:00

abstract：:Volume and morphology of chondrocytes in osteoarthritic human hip joint articular cartilage were characterized, and their relationship to tissue structure and function was determined. Human osteochondral articular cartilage samples (n=16) were obtained from the femoral heads of nine patients undergoing total hip arthr...

journal_title：Connective tissue research

authors： Huttu MR,Puhakka J,Mäkelä JT,Takakubo Y,Tiitu V,Saarakkala S,Konttinen YT,Kiviranta I,Korhonen RK

更新日期：2014-08-01 00:00:00

abstract：:White Carneau pigeons have previously been shown to be genetically susceptible to the development of spontaneous atherogenesis. The severity of development of atheromatous lesions is considerably greater than a more resistant breed of Show Racer pigeons. Analysis of levels of total hydroxyproline and isodesmosine in t...

journal_title：Connective tissue research

authors： Park HS,Kniep AC,Smith SC,Robie SM,Smith EC,Yu SY,Mackenzie JW,Scott GE,Boyd CD

更新日期：1990-01-01 00:00:00

abstract：:Studies were designed to test the hypothesis that plasma- and serum-deprived embryonic cells and tissues in vitro are capable of producing growth regulating factors which augment cartilage, bone and tooth induction during mouse mandibular process development. Embryonic mouse first branchial arch-derived mandibular pro...

journal_title：Connective tissue research

authors： Slavkin HC,Sasano Y,Kikunaga S,Bessem C,Bringas P Jr,Mayo M,Luo W,Mak G,Rall L,Snead ML

更新日期：1990-01-01 00:00:00

abstract：:The crystal ghosts represent a crystal associated organic material which is stained by acidic phosphotungstic acid, periodic acid-silver methenamine and periodic acid-thiosemicarbazide-osmium, and is reactive with cations and with colloidal iron at pH 2.0, and unreactive after methylation and saponification. These res...

journal_title：Connective tissue research

authors： Bonucci E,Silvestrini G,di Grezia R

更新日期：1989-01-01 00:00:00

abstract：:A partially purified BMP preparation was combined with a fibrous glass membrane (FGM) or porous particles of hydroxyapatite (PPHAP), and then implanted subcutaneously into the backs of rats. As a control of these new carriers, a conventional carrier of insoluble bone matrix (IBM) was also used. These new geometrically...

journal_title：Connective tissue research

authors： Kuboki Y,Saito T,Murata M,Takita H,Mizuno M,Inoue M,Nagai N,Poole AR

更新日期：1995-01-01 00:00:00

abstract：:The effects of two forms of elastase on the Young's Modulus of elastic tissue have been studied. The monomeric, calcium poor form of the enzyme lowers the value of the Young's Modulus before an appreciable amount of protein is taken into solution. The polymeric, calcium rich enzyme on the other hand degrades the prote...

journal_title：Connective tissue research

authors： Hall DA

更新日期：1976-01-01 00:00:00

abstract：AIMS:The structural organization of collagen from mineralized tissues, such as dentin and bone, has been a topic of debate in the recent literature. Recent reports have presented novel interpretations of the complexity of collagen type I at different hierarchical levels and in different tissues. Here, we investigate th...

journal_title：Connective tissue research

authors： Bertassoni LE,Swain MV

更新日期：2017-09-01 00:00:00

abstract：:The resorption of devitalized bone by isolated osteoclasts in culture was studied by scanning electron microscopy. Osteoclasts attached to the bone and resorbed mineral but left most of matrix collagen undigested in the resorption pits. Postculture-treatment of bone substrate with collagenase completely removed the ma...

journal_title：Connective tissue research

authors： Shimizu H,Sakamoto S,Sakamoto M

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The presence of genetic variants in uric acid (UA) transporters can be associated with hyperuricemia, and therefore with an increased risk of monosodium urate (MSU) crystal precipitation. The inflammatory process triggered by these crystals leads to cartilage damage, which, in turn, could promote knee osteoa...

journal_title：Connective tissue research

authors： Fernández-Torres J,Martínez-Nava GA,Oliviero F,López-Reyes AG,Martínez-Flores K,Garrido-Rodríguez D,Francisco-Balderas A,Zamudio-Cuevas Y

更新日期：2019-05-01 00:00:00

abstract：:We examined the effects of several variables on the ratio of type I:type III collagen secreted by human caucasian skin fibroblasts in normal and osteogenesis imperfecta (OI) phenotypes. Isotopically labelled collagen extracted from fibroblast medium was analyzed by DEAE-cellulose chromatography and identified by appro...

journal_title：Connective tissue research

authors： Fraser J,Lancaster GA,Scriver CR

更新日期：1983-01-01 00:00:00

abstract：:Since hyaluronan anchors the proteoglycan-rich pericellular matrix to chondrocytes, hyaluronan-cell interactions may direct cartilage matrix assembly. To test this hypothesis, the competitive binding of hyaluronan hexasaccharides for native hyaluronan during matrix assembly, accumulation and retention in embryonic car...

journal_title：Connective tissue research

authors： Maleski MP,Knudson CB

更新日期：1996-01-01 00:00:00

abstract：:The matrix metalloproteinases collagenase (MMP-1) and stromelysin (MMP-3) are often coordinately expressed, and their promoters contain similar regulatory elements, including an AP-1 site at about -70. There are, however, additional sequences including an adjacent ETS site at about -90 in both promoters, and a NIP (nu...

journal_title：Connective tissue research

authors： White LA,Maute C,Brinckerhoff CE

更新日期：1997-01-01 00:00:00

abstract：:To study the glycosylation of glomerular basement membrane collagen (GBMC) in diabetes, kidneys were obtained at autopsy from 5 patients with insulin-requiring diabetes of long duration and diabetic complications, and from 5 control subjects. Glomeruli were prepared by sieving and collagen was isolated by limited peps...

journal_title：Connective tissue research

authors： Uitto J,Perejda AJ,Grant GA,Rowold EA,Kilo C,Williamson JR

更新日期：1982-01-01 00:00:00

abstract：:Cell cultures propagated from fetal bovine ligamentum nuchae were found to accumulate an extensive extracellular matrix containing collagen and elastic fibers when maintained for periods up to 8 weeks. The synthesis by these cells of two glycoproteins, designated MFP I and MFP II, which are immunologically related to ...

journal_title：Connective tissue research

authors： Sear CH,Jones CJ,Knight KR,Grant ME

更新日期：1981-01-01 00:00:00

abstract：:The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. One of these was found to have similar molecular ...

journal_title：Connective tissue research

authors： Hincke MT

更新日期：1995-01-01 00:00:00