The physical properties of elastic fibers and elastolysis.

abstract：:Purpose/Aim: Knee meniscus is a wedge-shaped fibrocartilaginous tissue, playing important roles in maintaining joint stability and function. Injuries to the meniscus, particularly with the avascular inner third zone, hardly heal and frequently progress into structural breakdown, followed by the initiation of osteoarth...

journal_title：Connective tissue research

authors： Tarafder S,Park G,Lee CH

更新日期：2020-05-01 00:00:00

abstract：:Abnormal polyanion metabolism in cultured fibroblasts from patients with pseudoxanthoma elasticum (PXE) was studied by incubating normal and PXE fibroblasts in culture medium containing 35SO4 for 96 hr and measuring differences in secreted 35SO4-labelled proteoglycans (35S-PG). PXE medium contained less high molecular...

journal_title：Connective tissue research

authors： Gordon SG,Overland M,Foley J

更新日期：1978-01-01 00:00:00

abstract：:Scanning electron microscopy and high angle X-ray diffraction were used to define the relationship between collagen and elastin of bovine aortic wall. The diffraction pattern shows on one hand that the broad rings at 4.5 A and 9 A, due to elastin, do not orient on stretching and on the other hand, that the collagen ri...

journal_title：Connective tissue research

authors： Bigi A,Ripamonti A,Roveri N

更新日期：1977-01-01 00:00:00

abstract：:Parietal yolk sacs isolated from 14.5-day rat embryos and incubated in vitro with either [14C]proline, [3H]mannose or 3H-labeled amino acid mixture synthesized and secreted basement membrane collagenous and noncollagenous glycoprotein components with relative molecular weights of 350,000 (350K), 220,000 (220K), 185,00...

journal_title：Connective tissue research

authors： Clark CC,Kefalides NA

更新日期：1982-01-01 00:00:00

abstract：:The biological effects of isolated soluble dentin extracellular matrix components on the induction of reparative dentinogenesis in exposed cavities in ferret canine teeth have been shown to be blocked by immobilizing the extracellular matrix components on nitrocellulose or Millipore membranes during implantation. This...

journal_title：Connective tissue research

authors： Smith AJ,Tobias RS,Cassidy N,Bégue-Kirn C,Ruch JV,Lesot H

更新日期：1995-01-01 00:00:00

abstract：:The purpose of this study was to investigate overall degradative changes occurring to enamel matrix proteins in small, freeze-dried pieces of rat incisor enamel homogenized and incubated directly for 0-48 hours in a synthetic enamel fluid solution (165 mM total ionic strength with 0.153 mM calcium chloride) versus oth...

journal_title：Connective tissue research

authors： Smith CE,Chen WY

更新日期：1998-01-01 00:00:00

abstract：:The majority of patients eligible for periodontal regenerative therapies are aged subjects. Since periodontal ligament cells (PDLC) are essential for periodontal regeneration, the aim of the present study was to determine the effect of cellular aging on PDLC, including genes associated with extracellular matrix metabo...

journal_title：Connective tissue research

authors： Benatti BB,Silvério KG,Casati MZ,Sallum EA,Nociti FH Jr

更新日期：2008-01-01 00:00:00

abstract：OVERVIEW:Periostin (POSTN) is critical to bone and dental tissue morphogenesis, postnatal development, and maintenance; however, its roles in tissue repair and regeneration mediated by human periodontal ligament mesenchymal stem cells (PDLSCs) remain unclear. The present study was designed to evaluate the effects of PO...

journal_title：Connective tissue research

authors： Wu Z,Dai W,Wang P,Zhang X,Tang Y,Liu L,Wang Q,Li M,Tang C

更新日期：2018-03-01 00:00:00

abstract：:Large joint arthrofibrosis and scarring, involving the shoulder, elbow, hip, and knee, can result in the loss of function and immobility. The pathway of joint contracture formation is still being elucidated and is due to aberrations in collagen synthesis and misorientation of collagen fibrils. Novel antibodies are bei...

journal_title：Connective tissue research

authors： Chen AF,Lee YS,Seidl AJ,Abboud JA

更新日期：2019-01-01 00:00:00

abstract：:The menisci are intricately organized structures that perform many tasks in the knee. We review their structure and function and introduce new data about their tibial and femoral surfaces. As the femur and tibia approach each other when the knee is bearing load, circumferential tension develops in the menisci, enablin...

journal_title：Connective tissue research

authors： Andrews SHJ,Adesida AB,Abusara Z,Shrive NG

更新日期：2017-01-01 00:00:00

abstract：AIM:To investigate the effect of extracellular matrix (ECM) proteins on characteristics of mesenchymal stem cells (MSCs) and tendon-derived cells (TDCs). MATERIALS AND METHODS:MSCs and TDCs, cultured in a monolayer (2D) or hydrogels (3D), with or without ECM protein supplementation, and on a non-viable native tendon (...

journal_title：Connective tissue research

authors： Clements LE,Garvican ER,Dudhia J,Smith RK

更新日期：2016-11-01 00:00:00

abstract：:The binding of highly purified bovine aortic lysyl oxidase to native fibrils of type I collagen has been measured by assay of unbound lysyl oxidase activity in the supernatants of enzyme-collagen mixtures after centrifugation. The apparent binding affinity of lysyl oxidase for native fibrils is quite similar to that f...

journal_title：Connective tissue research

authors： Cronlund AL,Smith BD,Kagan HM

更新日期：1985-01-01 00:00:00

abstract：:The in-vitro fluoride treatment technique has been introduced to investigate the composite behavior of bone tissue. Bone tissue with different mechanical properties can be obtained by varying the concentration, pH and immersion time in fluoride ion solutions. The chemical and physical changes in intact pieces of bone ...

journal_title：Connective tissue research

authors： Kotha SP,DePaula CA,Koike K,Pan Y,Ohno M,Abjornson C,Rangarajan S,Guzelsu N

更新日期：2002-01-01 00:00:00

abstract：:STR/ort mice develop a naturally occurring osteoarthritis (OA) of the knee joints. However, the evaluation of early OA changes has been difficult due to variability caused by gender, individual differences, and differences between the right and left lower limbs. The objective of this study was to analyze the variabili...

journal_title：Connective tissue research

authors： Naruse K,Urabe K,Jiang SX,Uchida K,Kozai Y,Minehara H,Mikuni-Takagaki Y,Kashima I,Itoman M

更新日期：2009-01-01 00:00:00

abstract：:Raman spectra have been determined for hyaluronan, chondroitin-4-sulfate, chondroitin-6-sulfate, aggrecan monomers and aggregates. The nature of the saccharides and the pattern of sulfation can be discerned. There were only small spectral changes with pH and ionic composition. Differences between hydroxyl vibrations, ...

journal_title：Connective tissue research

authors： Ellis R,Green E,Winlove CP

更新日期：2009-01-01 00:00:00

abstract：:The expression of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) by human vascular smooth muscle cells (SMC) was monitored as a function of the phenotypic modulation in vitro. Cell phenotype was manipulated by varying serum concentration and cell density. Synthetic phenotype was characterized by a minim...

journal_title：Connective tissue research

authors： Kato S,Yasukawa H,Fujii T,Yamaguchi M,Miyagi N,Okamoto K,Wada Y,Miyamoto T,Morimatsu M,Fox JC

更新日期：2000-01-01 00:00:00

abstract：:Since hyaluronan anchors the proteoglycan-rich pericellular matrix to chondrocytes, hyaluronan-cell interactions may direct cartilage matrix assembly. To test this hypothesis, the competitive binding of hyaluronan hexasaccharides for native hyaluronan during matrix assembly, accumulation and retention in embryonic car...

journal_title：Connective tissue research

authors： Maleski MP,Knudson CB

更新日期：1996-01-01 00:00:00

abstract：:Bone morphogenetic protein-2 (BMP-2) is a multi-functional growth factor belonging to the transforming growth factor β superfamily that has a broad range of activities that affect many different cell types. BMP-2 induces odontoblastic differentiation of human dental pulp cells (DPCs), but the underlying mechanism rema...

journal_title：Connective tissue research

authors： Qin W,Liu P,Zhang R,Huang S,Gao X,Song Z,Wang R,Chen L,Guo B,Lin Z

更新日期：2014-06-01 00:00:00

abstract：:The desmoplastic response to breast carcinoma is being studied. The stimulation of stromal cell proliferation by a preformed breast tumor matrix was shown. An additional mechanism for stimulating scleroprotein deposition is described here. On a per-cell basis, the synthesis of collagen and elastin was increased by 50%...

journal_title：Connective tissue research

authors： Kao RT,Hall J,Stern R

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Orthodontic tooth movement occurs during the bone remodeling induced by therapeutic mechanical strain. It is important to investigate the relation between the strength of mechanical stress and bone formation activity. The aim of this study was to determine the effect of high-magnitude mechanical strain on bone ...

journal_title：Connective tissue research

authors： Fushiki R,Mayahara K,Ogawa M,Takahashi Y,Karasawa Y,Tsurumachi N,Tamura T,Shimizu N

更新日期：2015-01-01 00:00:00

abstract：:By using ultramorphological and biochemical methods, we analyzed the regional differences between the three parts of the equine superficial digital flexor tendon (SDFT), namely, the myotendinous junction (MTJ), middle metacarpal (mM), and osteotendinous junction (OTJ). Cross-sectional images showed unique distribution...

journal_title：Connective tissue research

authors： Watanabe T,Imamura Y,Hosaka Y,Ueda H,Takehana K

更新日期：2007-01-01 00:00:00

abstract：:Recently our laboratory has reported, in a lacerated flexor tendon model, that the "early turnover" phase of the repair process extends for a longer period of time in vivo than previously documented. The extensive turnover of the collagenous matrix was consistent with the presence of collagenolytic activity in repairi...

journal_title：Connective tissue research

authors： Russell JE,Manske PR

更新日期：1989-01-01 00:00:00

abstract：:The connective tissue protein elastin is largely responsible for maintaining the elasticity of major blood vessels and lung tissue. Comparatively few studies have been made of the immunologic properties of elastin because of its high degree of insolubility and because of its apparent limited capacity to elicit precipi...

journal_title：Connective tissue research

authors： Kucich U,Christner P,Rosenbloom J,Weinbaum G

更新日期：1981-01-01 00:00:00

abstract：:Cumulative damage to long-lived connective tissue proteins play a key role in the development of age-related human diseases such as cardiovascular stiffening and age-related macular degeneration. The processes that result in the accumulation of increasingly insoluble, undigestible damaged collagen are only partially k...

journal_title：Connective tissue research

authors： Paik DC,Saito LY,Sugirtharaj DD,Holmes JW

更新日期：2006-01-01 00:00:00

abstract：:Odontogenesis involves a complex series of processes including epithelial-mesenchymal interactions, morphogenesis, differentiation, fibrillogenesis, and mineralization. Extracellular (ECM) remodeling plays a critical role in the rapid morphological changes that accompany these events. It is proposed that matrix metall...

journal_title：Connective tissue research

authors： Randall LE,Hall RC

更新日期：2002-01-01 00:00:00

abstract：:Growth factors were historically defined as molecules produced by the body to regulate cell growth and proliferation. After the identification of their receptors and the intracellular signaling machinery they activate, it is now clear that they are involved in the regulation of multiple processes essential for develop...

journal_title：Connective tissue research

authors： Oehrl W,Panayotou G

更新日期：2008-01-01 00:00:00

abstract：:Laminin promotes adhesion of various cell types via multiple interactions with cell surface components. We have used a laminin domain involved in adhesion of melanoma cells, peptide F9 (Charonis et al., J. Cell Biol. 107:1253 [( 1988]), to examine its specific interaction with cell surface components. Cells were surfa...

journal_title：Connective tissue research

authors： Koliakos GG,Tsilibary EC,Charonis AS

更新日期：1991-01-01 00:00:00

abstract：:Radiation therapy is one of the routine treatment modalities for cancer patients. Ionizing radiation (IR) can induce bone loss, and consequently increases the risk of fractures with delayed and nonunion of the bone in the cancer patients who receive radiotherapy. The orchestrated bone remodeling can be disrupted due t...

journal_title：Connective tissue research

authors： Zhang J,Qiu X,Xi K,Hu W,Pei H,Nie J,Wang Z,Ding J,Shang P,Li B,Zhou G

更新日期：2018-11-01 00:00:00

abstract：:Epithelial-mesenchymal interactions are required for tissue growth and gene expression patterns during odontogenesis. We showed previously that Sonic hedgehog (SHH) is detectable in both dental epithelium and mesenchyme, while Shh transcripts are present in dental epithelium only, suggesting that SHH functions as an a...

journal_title：Connective tissue research

authors： Wu C,Shimo T,Liu M,Pacifici M,Koyama E

更新日期：2003-01-01 00:00:00

abstract：:The small leucine-rich repeat proteoglycans (SLRPs) constitute a group of structurally and functionally related molecules that participate in the organization of the extracellular matrix ECM and have important effects on cell behavior. Osteosarcomas are heterogeneous bone tumors whose common characteristic is the prod...

journal_title：Connective tissue research

authors： Nikitovic D,Berdiaki K,Chalkiadaki G,Karamanos N,Tzanakakis G

更新日期：2008-01-01 00:00:00