Abstract:
:Fusion experiments with three colonies (AC-BC-BD) by Tanaka and Watanabe indicated that the mixture of blood from two nonfusible colonies induced a "nonfusion" reaction (NFR)-like responses. Thus, artificial mixture of the blood from two nonfusible colonies is expected to result in NFR-like reactions. The present study deals with an in vivo bioassay using syngeneic and allogeneic blood injections. Syngeneic injection of whole blood induced no response, while allogeneic injection of whole blood induced inflammatory responses indicating recognition of allogeneic tissue. Syngeneic injection of blood plasma or blood cells induced no response. On the other hand, allogeneic injection of blood cells resulted in a response similar to that of whole blood injections. Allogeneic blood plasma induced only weak responses. It is hypothesized that NFR is initiated by the mutual interaction between blood cells and blood humoral factor(s).
journal_name
Dev Comp Immunoljournal_title
Developmental and comparative immunologyauthors
Taneda Y,Watanabe Hdoi
10.1016/s0145-305x(82)80007-4subject
Has Abstractpub_date
1982-04-01 00:00:00pages
243-52issue
2eissn
0145-305Xissn
1879-0089pii
S0145-305X(82)80007-4journal_volume
6pub_type
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