当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > Jagged-1hi or Delta-1hi thymic stromal cell populations can trigger acquisition of Thy-1 and loss of B220.

Jagged-1hi or Delta-1hi thymic stromal cell populations can trigger acquisition of Thy-1 and loss of B220.

Abstract：

:Effects of endogenous Notch ligands Jagged-1 and Delta-1 on maturation markers in adult mouse lymphocytes were checked in vitro on putative thymocyte precursors from bone marrow and on DN3 cells from the thymus. Both populations were cocultured with stromal cells (Small M, Histochem Cell Biol 2005;123:513) naturally expressing high levels of either Jagged-1 or Delta-1. Initially the bone marrow cells were Thy-1.2(neg) while the majority were B220(hi). These trends were reversed by culture on both the Jagged-1(hi) and Delta-1(hi) monolayers. Then DN3 thymocytes were cultured with stroma expressing these two ligands and the T cell receptor beta chain was expressed more clearly after coculture on Delta-1(hi) stroma. These findings indicate that stromal cells with endogenous Jagged-1 as well as Delta-1 could initiate early changes toward T cell commitment while Delta-1 favored later alphabeta-TCR development.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Small M

doi

10.1016/j.dci.2005.12.003

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

966-73

issue

10

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(05)00240-5

journal_volume

30

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • Dynamics of immune cell infiltration in the caecal lamina propria of chickens after neonatal infection with a Salmonella enteritidis strain.

    abstract：:Dynamics of leucocyte infiltration and bacterial invasion in the caecal wall were studied after oral infection of 2-day-old chicks with Salmonella enterica ser. Enteritidis. Bacteria invaded the lamina propria of the caecal wall from 12h post-challenge onwards. Bacteriological examination of internal organs (liver, sp...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(01)00084-2

    authors： Van Immerseel F,De Buck J,De Smet I,Mast J,Haesebrouck F,Ducatelle R

    更新日期：2002-05-01 00:00:00

  • The Toll immune signaling pathway control conserved anti-dengue defenses across diverse Ae. aegypti strains and against multiple dengue virus serotypes.

    abstract：:Dengue virus has become one of the most important arboviral pathogens affecting the world today. The virus is transmitted among humans by the mosquitoes Aedes aegypti and Ae. albopictus. Like other vector-borne pathogens, this virus encounters innate immune defenses within the mosquito vector that limit infection. We ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.01.006

    authors： Ramirez JL,Dimopoulos G

    更新日期：2010-06-01 00:00:00

  • Lipopolysaccharide enhances bactericidal activity in Dictyostelium discoideum cells.

    abstract：:Innate immune cells respond to invading microbes upon detection of pathogen-associated molecular patterns (PAMPS). PAMP-recognition machinery is evolutionarily conserved, allowing for characterization in model organisms. The model organism Dictyostelium discoideum can exist as single-celled amoebae, which phagocytize ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.03.018

    authors： Walk A,Callahan J,Srisawangvong P,Leuschner J,Samaroo D,Cassilly D,Snyder ML

    更新日期：2011-08-01 00:00:00

  • Receptors for complement on echinoid phagocytes. I. The opsonic effect of vertebrae sera on echinoid phagocytosis.

    abstract：:The ingestion of sheep erythrocytes (SRBC) by echinoid phagocytes was greatly increased after treatment of SRBC with sera from mouse, human and fish. The opsonic principle in the sera was heat labile (56 degrees C 1/2 hr). Opsonization with mammalian sera was studied more extensively. It was dependent on pre-sensitiza...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(82)80028-1

    authors： Bertheussen K,Seljelid R

    更新日期：1982-07-01 00:00:00

  • Thioredoxin peroxidase gene is involved in resistance to biocontrol fungus Nomuraea rileyi in Spodoptera litura: gene cloning, expression, localization and function.

    abstract：:Thioredoxin peroxidases (Tpxs) are a ubiquitous family of antioxidant enzymes that play important roles in protecting organisms against oxidative stress. Here, one Tpx was cloned from Spodoptera litura named as SlTpx. The full-length cDNA consists of 1165 bp with 588 bp open reading frame, encoding 195 amino acids. Th...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.11.012

    authors： Chen H,Yin Y,Feng E,Li Y,Xie X,Wang Z

    更新日期：2014-05-01 00:00:00

  • Mitigation of ER-stress and inflammation by chemokine (C-C motif) ligand 21 during early pregnancy.

    abstract：:The immune system plays an important role in pregnancy. Chemokines recruit leukocytes at the maternal-fetal interface during early pregnancy. However, the role of the chemokine, C-C motif chemokine ligand 21 (CCL21), is less known. The aim of this study was to identify the expression of CCL21 and its receptor, CCR7, i...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.01.016

    authors： Bae H,Lim W,Bazer FW,Whang KY,Song G

    更新日期：2019-05-01 00:00:00

  • CMPK2 of triploid crucian carp is involved in immune defense against bacterial infection.

    abstract：:Cytidine/uridine monophosphate kinase 2 (CMPK2) is a thymidylate kinase and in mammals is known to be involved in mitochondrial DNA (mtDNA) synthesis and antiviral immunity. However, very little is known about the function of CMPK2 in fish. With an aim to elucidate the antimicrobial mechanism of CMPK2 in fish, we in t...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103924

    authors： Feng C,Tang Y,Liu X,Zhou Z

    更新日期：2021-03-01 00:00:00

  • The expression of CD8α discriminates distinct T cell subsets in teleost fish.

    abstract：:CD8, belonging to the TCR complex, is the main marker molecule of CTLs. Although CD8 genes have been detected in many fish species, the analysis of teleost CD8+ cells has been limited because of the lack of antibodies. Using newly established mAbs against rainbow trout CD8α, we found high ratios of CD8α+ cells in trou...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.02.008

    authors： Takizawa F,Dijkstra JM,Kotterba P,Korytář T,Kock H,Köllner B,Jaureguiberry B,Nakanishi T,Fischer U

    更新日期：2011-07-01 00:00:00

  • Immunogenetics of disease resistance in fish: a comparative approach.

    abstract：:The study of the genetic regulation of infectious disease resistance depends on the availability of inbred lines or selection lines of the species under investigation. The small numbers of such lines of fish has limited the strategy in teleosts to studies of associations between disease and immune/health traits. Attem...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(96)00032-8

    authors： Wiegertjes GF,Stet RJ,Parmentier HK,van Muiswinkel WB

    更新日期：1996-11-01 00:00:00

  • Changes in mucosal and serum immunoglobulin levels of California sea lions during early development.

    abstract：:To date, most studies on pinniped immunoglobulins have focused on circulating antibodies. However, systemic and local immune activities differ in terms of maturation, intensity, and types of effectors that participate. Here, we examined levels of three immunoglobulin isotypes, IgG, IgM and IgA, in the blood and mucosa...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.08.006

    authors： Espinosa-de Aquino W,Bailey M,Acevedo-Whitehouse K

    更新日期：2017-12-01 00:00:00

  • Comparison of suppressor cells obtained from tumor-allosensitized adult and untreated neonatal mice.

    abstract：:Splenic suppressor cells from neonatal ("intrinsic") and adult (tumor-allosensitized) mice were compared. Both are non-antigen specific and non-H-2 restricted, and are Ly1+2+, I-J+, QA2+ T-cells. Injection of adult peritoneal exudate cells into neonates or adult tumor-allosensitized mice decreases suppressor cell acti...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(85)90066-7

    authors： Argyris BF

    更新日期：1985-01-01 00:00:00

  • Molecular cloning, characterization and function of a germinal center kinase MST4 gene from Litopenaeus vannamei in response to Vibrio alginolyticus challenge in TLR-TRAF6 signaling pathway.

    abstract：:The serine/threonine protein kinase MST4 plays multiple roles in the regulation of signaling pathways that govern cellular processes including mitosis, migration, homeostasis, polarity, proliferation, differentiation and apoptosis. Here we report the identification and characterization of the full-length sequence of L...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.03.026

    authors： Zhao CS,Huang D,Peng T,Huang MZ,Xie CY,Chen J,Kong JR,Xie RC,Liu Y,Wang WN

    更新日期：2017-08-01 00:00:00

  • Molecular cloning and characterisation of chicken IL-18 binding protein.

    abstract：:The human IL-1 receptor family is comprised of 11 membrane bound or soluble receptors and the IL-18 binding protein (IL-18BP). These receptors are dispersed across seven genomic loci, with the majority at a single locus. Direct orthologues were identified in the chicken at conserved genomic loci; however, the IL-18BP ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103850

    authors： Gibson MS,Steyn A,Kealy D,Kaspers B,Fife MS

    更新日期：2021-01-01 00:00:00

  • Identification and characterization of the first reptilian CD9, and its expression analysis in response to bacterial infection.

    abstract：:In this study, a CD9 homologue in a reptile, Chinese soft-shelled turtle, has been cloned and identified for the first time. The full-length cDNA of turtle CD9 was 1146bp and contained a 672bp open reading frame (ORF) coding for a protein of 224 amino acids. Four transmembrane domains (TMs) divided the turtle CD9 into...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.09.001

    authors： Zhou X,Feng H,Guo Q,Dai H

    更新日期：2010-02-01 00:00:00

  • Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.

    abstract：:The chemokine RANTES plays an essential role in inflammation and immune response. In this study, we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription. Analyses of a series of 5' deletion constructs demons...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.10.008

    authors： Wang D,Fang L,Li P,Chen Q,Luo R,Chen H,Xiao S

    更新日期：2011-03-01 00:00:00

  • Age-related changes of naive and memory CD4 rat lymphocyte subsets in mucosal and systemic lymphoid organs.

    abstract：:The purpose of this study was to investigate in rats, by double-label immunofluorescence and flow cytometric analysis, the age related changes in the CD4 subset of gut-associated lymphoid tissues and spleen. We found that the percentage of CD4+ T cells in Peyer's patches (PP) and spleen (SP) increased during the first...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(97)00023-2

    authors： Fló J,Massouh E

    更新日期：1997-09-01 00:00:00

  • Role of lectins in the innate immunity of horseshoe crab.

    abstract：:We have purified five types of lectins, named tachylectins, from circulating hemocytes and hemolymph plasma of the Japanese horseshoe crab, Tachypleus tridentatus. Tachylectin-1 interacts with Gram-negative bacteria probably through 2-keto-3-deoxyoctonate, one of the constituents of lipopolysaccharides (LPS). Tachylec...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(99)00019-1

    authors： Kawabata S,Iwanaga S

    更新日期：1999-06-01 00:00:00

  • Proteomic analysis of host responses to Marek's disease virus infection in spleens of genetically resistant and susceptible chickens.

    abstract：:Resistance to Marek's disease (MD) in chickens is genetically regulated and there are lines of chickens with differential susceptibility or resistance to this disease. The present study was designed to study comparative changes in the spleen proteomes of MD-susceptible B19 and MD-resistant B21 chickens in response to ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.01.016

    authors： Thanthrige-Don N,Parvizi P,Sarson AJ,Shack LA,Burgess SC,Sharif S

    更新日期：2010-07-01 00:00:00

  • The amphibian (Xenopus laevis) colony-stimulating factor-1 and interleukin-34-derived macrophages possess disparate pathogen recognition capacities.

    abstract：:Pathogens such as the Frog Virus 3 (FV3) ranavirus are contributing to the worldwide amphibian declines. While amphibian macrophages (Mϕs) are central to the immune defenses against these viruses, the pathogen recognition capacities of disparate amphibian Mϕ subsets remain unexplored. In turn, Mϕ differentiation and f...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.04.011

    authors： Yaparla A,Docter-Loeb H,Melnyk MLS,Batheja A,Grayfer L

    更新日期：2019-09-01 00:00:00

  • Evolution of thymus organogenesis.

    abstract：:The thymus is the primary organ for functional T lymphocyte development in jawed vertebrates. A new study in the jawless fish, lampreys, indicates the existence of a primitive thymus in these surviving representatives of the most ancient vertebrates, providing strong evidence of co-evolution of T cells and thymus. Thi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2012.01.002

    authors： Ge Q,Zhao Y

    更新日期：2013-01-01 00:00:00

  • Molecular cloning, expression and functional analysis of interleukin-8 (IL-8) in South African clawed frog (Xenopus laevis).

    abstract：:In this study, an IL-8 homologue has been cloned and identified from South African clawed frog Xenopus laevis (designated XlIL-8). The open reading frame (ORF) of XlIL-8 consists of 312 bases encoding a protein of 103 amino acids. The chemokine CXC domain, which contained Glu-Leu-Arg (ELR) motif and four cysteine resi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.04.005

    authors： Cui X,Han Y,Pan Y,Xu X,Ren W,Zhang S

    更新日期：2011-11-01 00:00:00

  • High sequence variability among hemocyte-specific Kazal-type proteinase inhibitors in decapod crustaceans.

    abstract：:Crustacean hemocytes were found to produce a large number of transcripts coding for Kazal-type proteinase inhibitors (KPIs). A detailed study performed with the crayfish Pacifastacus leniusculus and the shrimp Penaeus monodon revealed the presence of at least 26 and 20 different Kazal domains from the hemocyte KPIs, r...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.08.005

    authors： Cerenius L,Liu H,Zhang Y,Rimphanitchayakit V,Tassanakajon A,Gunnar Andersson M,Söderhäll K,Söderhäll I

    更新日期：2010-01-01 00:00:00

  • The oyster immunity.

    abstract：:Oysters, the common name for a number of different bivalve molluscs, are the worldwide aquaculture species and also play vital roles in the function of ecosystem. As invertebrate, oysters have evolved an integrated, highly complex innate immune system to recognize and eliminate various invaders via an array of orchest...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2017.05.025

    authors： Wang L,Song X,Song L

    更新日期：2018-03-01 00:00:00

  • Transfection of crayfish hematopoietic tissue cells.

    abstract：:Transfection is a powerful tool useful for studying gene function. Establishing transfection methods that enable highly efficient DNA uptake has become increasingly important. The crayfish hematopoietic tissue (Hpt) cell cultures have been proven to be suitable for studies on immunity and cell differentiation in crust...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.07.005

    authors： Shi H,Ruan L,Söderhäll I,Söderhäll K,Xu X

    更新日期：2018-11-01 00:00:00

  • Molecular cloning and expression analysis of mannose receptor C type 1 in grass carp (Ctenopharyngodon idella).

    abstract：:Mannose receptor C type 1 (MRC1) is a pattern-recognition receptor (PRR) which plays a significant role in immune responses. Much work on MRC1 has been done in mammals and birds while little in fish. In this study, we cloned and characterized MRC1 in grass carp (gcMR). The full-length gcMR contained 5291bp encoding a ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.10.006

    authors： Wang L,Liu L,Zhou Y,Zhao X,Xi M,Wei S,Fang R,Ji W,Chen N,Gu Z,Liu X,Wang W,Asim M,Liu X,Lin L

    更新日期：2014-03-01 00:00:00

  • Molecular cloning and characterisation of the griffon vulture (Gyps fulvus) toll-like receptor 1.

    abstract：:The toll-like receptor (TLR) family is an ancient pattern recognition receptor family, conserved from insects to mammals. Members of the TLR family are vital to immune function through the sensing of pathogenic agents and initiation of an appropriate immune response. In this study, we cloned a cDNA encoding for a grif...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2006.08.003

    authors： de la Lastra JM,de la Fuente J

    更新日期：2007-01-01 00:00:00

  • Porcine reproductive and respiratory syndrome virus infection activates IL-10 production through NF-κB and p38 MAPK pathways in porcine alveolar macrophages.

    abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is an emerging animal virus that has caused high economic losses for the swine industry worldwide. Previous in vitro and in vivo studies demonstrated that PRRSV infection induces significant production of interleukin 10 (IL-10), a pleiotropic cytokine with im...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.10.001

    authors： Song S,Bi J,Wang D,Fang L,Zhang L,Li F,Chen H,Xiao S

    更新日期：2013-03-01 00:00:00

  • Fish immune responses to parasitic copepod (namely sea lice) infection.

    abstract：:Parasitic copepods, in particular sea lice, have considerable impacts upon global freshwater and marine fisheries, with major economic consequences recognized primarily in aquaculture. Sea lice have been a contentious issue with regards to interactions between farmed and wild populations of fish, in particular salmoni...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2013.08.019

    authors： Fast MD

    更新日期：2014-04-01 00:00:00

  • Pre-acute hepadnaviral infection is associated with activation-induced apoptotic death of lymphocytes in the woodchuck (Marmota monax) model of hepatitis B.

    abstract：:Woodchucks (Marmota monax) infected with woodchuck hepatitis virus (WHV) represent a highly valuable immunopathogenic model of hepatitis B virus (HBV) infection. Both WHV and HBV are noncytopathic hepadnaviruses which induce a strong but delayed virus-specific cellular immune response believed to be a cause of hepatit...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.05.001

    authors： Gujar SA,Jenkins AK,Macparland SA,Michalak TI

    更新日期：2010-09-01 00:00:00

  • Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins.

    abstract：:Siglecs (sialic acid-binding immunoglobulin-type lectins) are a family of immune regulatory receptors predominantly found on the cells of the hematopoietic system. A V-set Ig-like domain mediates the recognition of different sialylated glycoconjugates, which can lead to the activation or inhibition of the immune respo...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2018.05.008

    authors： Bornhöfft KF,Goldammer T,Rebl A,Galuska SP

    更新日期：2018-09-01 00:00:00