Abstract:
:The avirulent Salmonella typhimurium galE strain G30, following oral feeding to mice, developed a state of immunity to a secondary oral challenge with virulent Salmonella typhimurium. This immunity was concommitant with the development of intestinal and serum antibodies and delayed-type hyepersensitivity (DTH) to Salmonella antigens. In contrast, repeated oral doses of a hybrid E. coli vaccine, which expresses the O antigens of Salmonella typhimurium, provided a lesser degree of immunity and, although able to stimulate the formation of serum antibodies, it elicited only a low level of intestinal antibodies and no measurable DTH.
journal_name
Med Microbiol Immunoljournal_title
Medical microbiology and immunologyauthors
Moser I,Hohmann A,Schmidt G,Rowley Ddoi
10.1007/BF02121760subject
Has Abstractpub_date
1980-01-01 00:00:00pages
119-28issue
2eissn
0300-8584issn
1432-1831journal_volume
168pub_type
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