Inducing protective antibodies against ring-infected erythrocyte surface peptide antigen of Plasmodium falciparum using immunostimulating complex (ISCOMs) delivery.

abstract：:A microcytoxicity assay with 3H-proline prelabeled target cells was used for the detection of sensitized lymphoid spleen cells from STU inbred mice inoculated with Moloney sarcoma virus (MSV-M) or ascitic MSV-M tumor cells. The target cell line was derived from ascitic MSV-M tumor cells. With regard to the specificity...

journal_title：Medical microbiology and immunology

authors： Weiland E,Mussgay M

更新日期：1976-06-01 00:00:00

abstract：:Cytomegaloviruses (CMVs) are large double-stranded DNA viruses that replicate slowly and cause life-long persisting infections in their hosts. To achieve this, the CMVs had to evolve numerous countermeasures against innate and adaptive immune responses. Induction of programmed cell death is one important host defense ...

journal_title：Medical microbiology and immunology

authors： Handke W,Krause E,Brune W

更新日期：2012-11-01 00:00:00

abstract：:Thrombi formation was demonstrated in mesenteric microcirculation of guinea pigs inoculated with Fusobacterium necrophorum and the bacterial hemagglutinin (HA). The thrombi were initially observed in venules and later, in arterioles. Immunofluorescence study revealed that the HA bound to the thrombi in the microcircul...

journal_title：Medical microbiology and immunology

authors： Kanoe M,Yamanaka M,Inoue M

更新日期：1989-01-01 00:00:00

abstract：:It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetr...

journal_title：Medical microbiology and immunology

authors： Jankovičová J,Neuerová Z,Sečová P,Bartóková M,Bubeníčková F,Komrsková K,Postlerová P,Antalíková J

更新日期：2020-08-01 00:00:00

abstract：:The aroB gene from Helicobacter pylori strain P1 was cloned and further characterized by sequence analysis and by functional complementation of the aroB mutation in Escherichia coli. The aroB gene encodes the enzyme 3-dehydroquinate synthase which catalyzes one of the early steps in the shikimate pathway. This pathway...

journal_title：Medical microbiology and immunology

authors： Bereswill S,Fassbinder F,Völzing C,Haas R,Reuter K,Ficner R,Kist M

更新日期：1997-10-01 00:00:00

abstract：:Moraxella catarrhalis is an important pathogen of respiratory and middle ear infections. We previously reported that the attachment of M. catarrhalis to pharyngeal epithelial cells is mediated by ganglioside M2 (GM2). Several sets of adhesins or receptors are involved in such attachment process. In this study, we used...

journal_title：Medical microbiology and immunology

authors： Ahmed K,Suzuki Y,Miyamoto D,Nagatake T

更新日期：2002-05-01 00:00:00

abstract：:Since the dynamics of transmission of human cytomegalovirus (HCMV) have not been clarified yet, we assessed a possible change in HCMV seroprevalence in Frankfurt am Main, Germany during the past twenty years and tried to detect variables with an impact on epidemiology. Between 1/1/1988 and 10/15/2008, a total of 54443...

journal_title：Medical microbiology and immunology

authors： Lübeck PR,Doerr HW,Rabenau HF

更新日期：2010-02-01 00:00:00

abstract：:The infant rat model is widely used to study the pathogenesis of meningitis caused by a variety of gram-positive and gram-negative bacteria. However, the interpretation of published results concerning meningitis is difficult in many records because the fact that blood contamination of the cerebrospinal fluid (CSF) can...

journal_title：Medical microbiology and immunology

authors： Vogel U,Steinmetz I,Frosch M

更新日期：1996-05-01 00:00:00

abstract：:Industrial and academic needs for innovation and fundamental research are essential and not widely different. Depending on the industrial setting, research and development (R&D) activities may be more focused on the developmental aspects given the need to ultimately sell useful products. However, one of the biggest di...

journal_title：Medical microbiology and immunology

authors： van Belkum A,Pelegrin AC,Datar R,Goyal M,Palmieri M,Mirande C,Chalansonnet V,Orenga S

更新日期：2020-06-01 00:00:00

abstract：:During normal interpandemic influenza seasons, immune responses to vaccines are quite predictable and meet the licensing criteria of the European Union (EU) Committee for Proprietary Medicinal Products (CPMP). In a pandemic situation, large sections, if not all of the community will be immunologically naïve and theref...

journal_title：Medical microbiology and immunology

authors： Wood JM,Nicholson KG,Stephenson I,Zambon M,Newman RW,Major DL,Podda A

更新日期：2002-12-01 00:00:00

abstract：:Porphyromonas gingivalis, a periodontal pathogen, is epidemiologically associated with oral squamous cell carcinoma (OSCC). Matrix metalloproteinase 9 (MMP9) which degrades the extracellular matrix and basement membrane components has been implicated in invasion and metastasis of tumor cells. We previously reported th...

journal_title：Medical microbiology and immunology

authors： Inaba H,Amano A,Lamont RJ,Murakami Y

更新日期：2015-10-01 00:00:00

abstract：:The effects of sheep anti-murine recombinant tumor necrosis factor-alpha (TNF-alpha) on resistance to Listeria monocytogenes infection were studied in T cell-deficient nu/nu mice. The sheep anti-TNF-alpha antibody preparation was specific for TNF since it neutralized 300 U of recombinant murine TNF-alpha in vitro at a...

journal_title：Medical microbiology and immunology

authors： Hauser T,Frei K,Zinkernagel RM,Leist TP

更新日期：1990-01-01 00:00:00

abstract：:A set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of inc...

journal_title：Medical microbiology and immunology

authors： Nord C-E,Linberg AA,Dahlbäck A

更新日期：1975-09-19 00:00:00

abstract：:Phosphorylcholine (ChoP) is covalently incorporated into bacterial surface structures, contributing to host mimicry and promoting adhesion to surfaces. Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which surface structures bear ChoP, and whethe...

journal_title：Medical microbiology and immunology

authors： Ihalin R,Zhong D,Karched M,Chen C,Asikainen S

更新日期：2018-11-01 00:00:00

abstract：:The present study was designed to determine whether tumor induction by 3-methylcholanthrene (MC), a carcinogenic hydrocarbon, can be inhibited by oral administration of Lactobacillus casei strain Shirota (LC). C3H/HeN mice were divided into four groups and assigned to the following treatments: treated with MC and give...

journal_title：Medical microbiology and immunology

authors： Takagi A,Matsuzaki T,Sato M,Nomoto K,Morotomi M,Yokokura T

更新日期：1999-12-01 00:00:00

abstract：:A 33-kDa protein (TB33) was isolated from a delipidated cell sonicate (CS) of Mycobacterium tuberculosis H37Rv (grown in Middlebrook 7H9 broth supplemented with glucose) using immobilized metal affinity chromatography (IMAC) on a nickel-nitrilotriacetic acid (Ni-NTA) column. TB33 could not be isolated from the culture...

journal_title：Medical microbiology and immunology

authors： Deshpande RG,Khan MB,Bhat DA,Navalkar RG

更新日期：1996-11-01 00:00:00

abstract：:Illness and death of mice infected by intracerebral inoculation with lymphocytic choriomeningitis virus are pathologic immune phenomena, and mice thus infected were protected when immunosuppressed with cyclosporin A (CSA), although the virus multiplied extensively in all major organs. Concentrations remained high as l...

journal_title：Medical microbiology and immunology

authors： Löliger C,Lehmann-Grube F

更新日期：1985-01-01 00:00:00

abstract：:We assessed whether the intracellular bacterium Chlamydia pneumoniae was present in post-mortem brain samples from patients with and without late-onset Alzheimer's disease (AD), since some indirect evidence seems to suggest that infection with the organism might be associated with the disease. Nucleic acids prepared f...

journal_title：Medical microbiology and immunology

authors： Balin BJ,Gérard HC,Arking EJ,Appelt DM,Branigan PJ,Abrams JT,Whittum-Hudson JA,Hudson AP

更新日期：1998-06-01 00:00:00

abstract：:Pteridine derivatives neopterin and 7,8-dihydroneopterin are produced by human macrophages and dendritic cells upon stimulation with interferon-gamma (IFN-gamma) and therefore become detectable in increased amounts in humans during cell-mediated (Th1-type) immune response. Compounds produced upon influence of cytokine...

journal_title：Medical microbiology and immunology

authors： Bratslavska O,Platace D,Miklasevics E,Fuchs D,Martinsons A

更新日期：2007-03-01 00:00:00

abstract：:The avirulent Salmonella typhimurium galE strain G30, following oral feeding to mice, developed a state of immunity to a secondary oral challenge with virulent Salmonella typhimurium. This immunity was concommitant with the development of intestinal and serum antibodies and delayed-type hyepersensitivity (DTH) to Salm...

journal_title：Medical microbiology and immunology

authors： Moser I,Hohmann A,Schmidt G,Rowley D

更新日期：1980-01-01 00:00:00

abstract：:A coupled luminescent method (CLM) based on glyceraldehyde-3-phosphate dehydrogenase released from injured target cells was used to evaluate the cytotoxicity of antigen-specific HLA class I-restricted CTLs. In contrast to established methods, CLM does not require the pretreatment of target cells with radioactive or to...

journal_title：Medical microbiology and immunology

authors： Ogbomo H,Geiler J,Leutz A,von Kietzell K,Michaelis M,Doerr HW,Cinatl J Jr

更新日期：2009-11-01 00:00:00

abstract：:Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper (Th) and regulatory T cells (Tregs). Then, aiming at clarifying the immune response, ...

journal_title：Medical microbiology and immunology

authors： Azevedo MCS,Marques H,Binelli LS,Malange MSV,Devides AC,Silva EA,Fachin LRV,Ghidella CC,Soares CT,Garlet GP,Rosa PS,Belone AFF,Trombone APF

更新日期：2017-12-01 00:00:00

abstract：:The purpose of this study was to characterize antigenic determinants on structural polypeptides of human immunodeficiency virus type 2 (HIV-2ben). Therefore, three HIV-2-specific monoclonal antibodies (mAbs) against the p24 core protein (gag) and one mAb against the gp130 envelope glycoprotein (env) were produced. In ...

journal_title：Medical microbiology and immunology

authors： Faisst AC,Otteken A,Nick S,Hunsmann G

更新日期：1993-07-01 00:00:00

abstract：:Turkey is seeing a steady rise in rates of HIV infection in the country. The number of individuals with HIV/AIDS was greater than 7000 in 2014 according to data released by the Ministry of Health, and heterosexual contacts were reported to be the main transmission routes. Istanbul has the highest number of reported ca...

journal_title：Medical microbiology and immunology

authors： Köksal MO,Beka H,Lübke N,Verheyen J,Eraksoy H,Cagatay A,Kaiser R,Akgül B,Agacfidan A

更新日期：2015-08-01 00:00:00

abstract：:The endogenous danger signal bradykinin was recently found implicated in the development of immunity against parasites via dendritic cells. We here report an essential role of the B(2) (B(2)R) bradykinin receptor in the early immune response against Listeria infection. Mice deficient in B(2)R (B(2)R(-/-) mice) were sh...

journal_title：Medical microbiology and immunology

authors： Kaman WE,Wolterink AF,Bader M,Boele LC,van der Kleij D

更新日期：2009-02-01 00:00:00

abstract：:To characterize the role of specific lymphocyte subsets in Chlamydia trachomatis infection, we established a murine model using the mouse pneumonitis agent (MoPn) of C. trachomatis and C.B-17 scid/scid (SCID) mice which lack functional B and T cells. After intraperitoneal inoculation with the bacteria, SCID mice devel...

journal_title：Medical microbiology and immunology

authors： Thoma-Uszynski S,Simnacher U,Marre R,Essig A

更新日期：1998-10-01 00:00:00

abstract：:Neutrophil extracellular traps (NETs) have recently been discovered as a central part of antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also generated upon non-infectious stimuli in various clinical settings. In acute or chronic inflammatory disorders aberrantly enhanced NET format...

journal_title：Medical microbiology and immunology

authors： Lögters T,Margraf S,Altrichter J,Cinatl J,Mitzner S,Windolf J,Scholz M

更新日期：2009-11-01 00:00:00

abstract：:In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4-6 weeks, followed by ivermectin (IVM) after 6 months. After 6-27 months, efficacy was evaluated by onchocercoma histology, PCR and microfilariae determination. Administration of doxycycline resulted in ...

journal_title：Medical microbiology and immunology

authors： Hoerauf A,Specht S,Büttner M,Pfarr K,Mand S,Fimmers R,Marfo-Debrekyei Y,Konadu P,Debrah AY,Bandi C,Brattig N,Albers A,Larbi J,Batsa L,Taylor MJ,Adjei O,Büttner DW

更新日期：2008-09-01 00:00:00

abstract：:Chronic hepatitis C virus (HCV) infections affect 71 million people worldwide, often resulting in severe liver damage. Since 2014 highly efficient therapies based on directly acting antivirals (DAAs) are available, offering cure rates of almost 100%, if the infection is diagnosed in time. It took more than a decade to...

journal_title：Medical microbiology and immunology

authors： Lohmann V

更新日期：2019-02-01 00:00:00

abstract：:The structural relation of YOP-1 of "european" and "american" Yersinia enterocolitica serotypes O:3, O:9, O:5,27, and O:8 and O:20, respectively, and Y. pseudotuberculosis serotypes I, II, and III was compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis and peptide mapping using Staphylococcus aureus ...

journal_title：Medical microbiology and immunology

authors： Mack D,Pulz M,Heesemann J

更新日期：1991-01-01 00:00:00