Influence of neopterin and 7,8-dihydroneopterin on the replication of Coxsackie type B5 and influenza A viruses.

abstract：:Neutrophil extracellular traps (NETs) have recently been discovered as a central part of antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also generated upon non-infectious stimuli in various clinical settings. In acute or chronic inflammatory disorders aberrantly enhanced NET format...

journal_title：Medical microbiology and immunology

authors： Lögters T,Margraf S,Altrichter J,Cinatl J,Mitzner S,Windolf J,Scholz M

更新日期：2009-11-01 00:00:00

abstract：:In resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen for early infections. We evaluated the performance of the antibody and antigen components of the...

journal_title：Medical microbiology and immunology

authors： Wratil PR,Rabenau HF,Eberle J,Stern M,Münchhoff M,Friedrichs I,Stürmer M,Berger A,Kuttner-May S,Münstermann D,Lucht A,Meixenberger K,Bannert N,Keppler OT

更新日期：2020-04-01 00:00:00

abstract：:When P3HR-1 lymphoblastoid cells expressing Epstein-Barr virus (EBV)-related antigens at very low frequency were cocultivated with human umbilical cord blood lymphocytes and the cell-free mixed culture fluid was applied to fresh cord lymphocytes, cells morphologically distinct from normal lymphocytes became evident af...

journal_title：Medical microbiology and immunology

authors： Aya T,Osato T

更新日期：1978-01-01 00:00:00

abstract：:The essential protein lysyl-tRNA synthetase (LysRS) exists in two unrelated forms, a class I and a class II-type aminoacyl-tRNA synthetase. Comparative genome sequence analysis revealed that Borrelia burgdorferi sensu lato, the etiological agent of Lyme disease, contains a class I-type LysRS, whereas its tick and mamm...

journal_title：Medical microbiology and immunology

authors： Mejlhede N,Monthán A,Theisen M,Ibba M

更新日期：2003-05-01 00:00:00

abstract：:The DNAs of two kinds of microorganisms from human leprosy lesion, Mycobacterium leprae and Corynebacterium tuberculostearicum (also known as "leprosy-derived corynebacterium" or LDC), have been analysed and compared with the genomes of reference bacteria of the CMN group (genera Corynebacterium, Mycobacterium and Noc...

journal_title：Medical microbiology and immunology

authors： Hottat F,Coene M,Cocito C

更新日期：1988-01-01 00:00:00

abstract：:Influenza remains an important threat for human health, despite the extensive study of influenza viruses and the production of effective vaccines. In contrast to virus genetics determinants, host genetic factors with clinical impact remained unexplored until recently. The association between three single nucleotide po...

journal_title：Medical microbiology and immunology

authors： Chatzopoulou F,Gioula G,Kioumis I,Chatzidimitriou D,Exindari M

更新日期：2019-10-01 00:00:00

abstract：:As enteroviruses are mainly transmitted by the fecal-oral route, this study was initiated to investigate the nature of the binding of enteroviruses to human skin. Using poliovirus 1, Mahoney, we investigated the overall effectiveness of soap and water hand-washing of 1 and 5 min duration. The virus-skin interaction wa...

journal_title：Medical microbiology and immunology

authors： Schürmann W,Eggers HJ

更新日期：1985-01-01 00:00:00

abstract：:NFR nude (nu/nu) and euthymic (+/nu) littermates were infected with coxsackievirus B3 (CBV-3) and assayed for virus persistence in the heart, pancreas and spleen, for development of myocarditis and for antibody production. The virus grew to higher titer and persisted longer in hearts of nu/nu mice. In both types of mi...

journal_title：Medical microbiology and immunology

authors： Schnurr DP,Schmidt NJ

更新日期：1984-01-01 00:00:00

abstract：:Due to its ability to attach to polymeric surfaces Staphylococcus epidermidis is a common pathogen in chronic, medical device-associated infections. Attached S. epidermidis displays reduced susceptibility against a variety of antimicrobial substances, and little correlation between standard susceptibility test results...

journal_title：Medical microbiology and immunology

authors： Knobloch JK,Von Osten H,Horstkotte MA,Rohde H,Mack D

更新日期：2002-10-01 00:00:00

abstract：:We have examined 118 oral squamous cell carcinomas, 72 oral leukoplakias, 12 cases of cheilitis and 65 of oral lichen planus for the presence of human papillomavirus (HPV) 6/11, 16 and 18 DNA by PCR/Southern blot hybridization. HPV DNA were found in 51/118 carcinomas (43.2%), in 16/72 (22.2%) leukoplakias, 3/12 (25.0%...

journal_title：Medical microbiology and immunology

authors： Ostwald C,Rutsatz K,Schweder J,Schmidt W,Gundlach K,Barten M

更新日期：2003-08-01 00:00:00

abstract：:The aroB gene from Helicobacter pylori strain P1 was cloned and further characterized by sequence analysis and by functional complementation of the aroB mutation in Escherichia coli. The aroB gene encodes the enzyme 3-dehydroquinate synthase which catalyzes one of the early steps in the shikimate pathway. This pathway...

journal_title：Medical microbiology and immunology

authors： Bereswill S,Fassbinder F,Völzing C,Haas R,Reuter K,Ficner R,Kist M

更新日期：1997-10-01 00:00:00

abstract：:Streptococcus pyogenes is a human pathogen which causes a spectrum of diseases ranging from pharyngitis to rheumatic fever, necrotising fasciitis and toxic shock syndrome. Development of a vaccine for S. pyogenes has been confounded both by the diversity of the disease-causing serotypes and the spectre of inadvertentl...

journal_title：Medical microbiology and immunology

authors： Radcliff FJ,Fraser JD,Proft T

更新日期：2015-04-01 00:00:00

abstract：:Recently we demonstrated that lack of mecA transcription was responsible for the decreased methicillin resistance phenotype of strongly slime-negative Staphylococcus epidermidis phase variants [Mempel M, Feucht H, Ziehbuhr W, Endres M, Laufs R, Grüter L (1994) Antimicrob Agents Chemother 38: 1251-1255]. In the present...

journal_title：Medical microbiology and immunology

authors： Mempel M,Müller E,Hoffmann R,Feucht H,Laufs R,Grüter L

更新日期：1995-10-01 00:00:00

abstract：:Killer cell immunoglobulin like receptors (KIRs) have a principal role in regulating the effector functions of NK cells, particularly in viral infections. The major ligands for KIRs are human leukocyte antigen (HLA) class I molecules. The aim of this study is to investigate the possible association of KIR genes, their...

journal_title：Medical microbiology and immunology

authors： Shah-Hosseini A,Jafari M,Mohammadi A,Sanaei R,Alavian SM,Doosti-Irani A,Nooradeh Keykavousi M,Tajik N

更新日期：2017-12-01 00:00:00

abstract：:9 antigen distribution and sensitivity to the bactericidal effect of normal human serum were determined in 485 Proteus strains isolated from urine, blood, wounds, and feces. Of all strains, 62% could be grouped according to 25 0 antigens. The most frequent one, 0 3, appeared in 13% of all the strains. In blood culture...

journal_title：Medical microbiology and immunology

authors： Larsson P,Olling S

更新日期：1977-07-18 00:00:00

abstract：:Outer membrane fractions (OMs) of nine Campylobacter (C.) jejuni and two C. coli strains belonging to different serovars, from human and various animal origins, were extracted by treatment with sodium N-lauryl sarcosinate. Using n-octyl-beta-D-glucopyranoside a 42-kDa protein and a flagella-enriched fraction were obta...

journal_title：Medical microbiology and immunology

authors： Moser I,Schröder WF,Hellmann E

更新日期：1992-01-01 00:00:00

abstract：:This is a summary of the recent work on some glycosidases of sand flies and their Leishmania parasites. Glycosidases catalyze the hydrolysis of complex sugar subunits of polysaccharides into simple sugars. Leishmania major parasites secrete chitinase and N-acetylglucosaminase, which enables them to survive in the gut ...

journal_title：Medical microbiology and immunology

authors： Jacobson RL,Schlein Y,Eisenberger CL

更新日期：2001-11-01 00:00:00

abstract：:It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetr...

journal_title：Medical microbiology and immunology

authors： Jankovičová J,Neuerová Z,Sečová P,Bartóková M,Bubeníčková F,Komrsková K,Postlerová P,Antalíková J

更新日期：2020-08-01 00:00:00

abstract：:The infant rat model is widely used to study the pathogenesis of meningitis caused by a variety of gram-positive and gram-negative bacteria. However, the interpretation of published results concerning meningitis is difficult in many records because the fact that blood contamination of the cerebrospinal fluid (CSF) can...

journal_title：Medical microbiology and immunology

authors： Vogel U,Steinmetz I,Frosch M

更新日期：1996-05-01 00:00:00

abstract：:We assessed whether the intracellular bacterium Chlamydia pneumoniae was present in post-mortem brain samples from patients with and without late-onset Alzheimer's disease (AD), since some indirect evidence seems to suggest that infection with the organism might be associated with the disease. Nucleic acids prepared f...

journal_title：Medical microbiology and immunology

authors： Balin BJ,Gérard HC,Arking EJ,Appelt DM,Branigan PJ,Abrams JT,Whittum-Hudson JA,Hudson AP

更新日期：1998-06-01 00:00:00

abstract：:Gliosis of glial fibrillary acidic protein (GFAP) associated astrocytes is considered to be one of the hallmarks of transmissible spongiform encephalopathies (TSEs). In the present study, remarkable GFAP-PrP(Sc) or GFAP-PrP(C) complexes were separately detected in the brain homogenates of 263 K (Scrapie)-infected or n...

journal_title：Medical microbiology and immunology

authors： Dong CF,Wang XF,Wang X,Shi S,Wang GR,Shan B,An R,Li XL,Zhang BY,Han J,Dong XP

更新日期：2008-12-01 00:00:00

abstract：:Both aging and treated human immunodeficiency virus (HIV) infection are characterized by low-level chronic inflammation and immune activation which contribute to the development of age-related diseases, frailty, and early mortality. Chronic cytomegalovirus (CMV) infection is highly prevalent in older adults and HIV-in...

journal_title：Medical microbiology and immunology

authors： Tavenier J,Margolick JB,Leng SX

更新日期：2019-08-01 00:00:00

abstract：:A total of 114 Clostridium difficile strains were analysed for a possible correlation between serological susceptibility to chloramphenicol, tetracycline and clindamycin, and serogrouping. All 17 chloramphenicol-resistant strains belonged to serovar I, while none of 32 tetracycline-resistant strains belonged to serova...

journal_title：Medical microbiology and immunology

authors： Nakamura S,Yamakawa K,Nakashio S,Kamiya S,Nishida S

更新日期：1987-01-01 00:00:00

abstract：:We have studied the incidence of enterotoxigenic and enteropathogenic Escherichia coli strains associated with infant diarrhoeal disease in Galicia (North-west Spain). During a period of 9 months we isolated heat-labile enterotoxin-positive strains in 2.1% of children with diarrhoea examined, whereas the production of...

journal_title：Medical microbiology and immunology

authors： Blanco J,González EA,Bernárdez I,Varela BR

更新日期：1983-01-01 00:00:00

abstract：:Cytomegaloviruses (CMVs) are large double-stranded DNA viruses that replicate slowly and cause life-long persisting infections in their hosts. To achieve this, the CMVs had to evolve numerous countermeasures against innate and adaptive immune responses. Induction of programmed cell death is one important host defense ...

journal_title：Medical microbiology and immunology

authors： Handke W,Krause E,Brune W

更新日期：2012-11-01 00:00:00

abstract：:We previously reported that Trypanosoma cruzi, the agent of Chagas disease, induces in congenitally infected fetuses a strong, adult-like parasite-specific CD8(+) T cell response producing IFN-γ (Hermann et al. in Blood 100:2153-2158, 2002). This suggests that the parasite is able to overcome the immaturity of neonata...

journal_title：Medical microbiology and immunology

authors： Rodriguez P,Carlier Y,Truyens C

更新日期：2012-05-01 00:00:00

abstract：:Streptomyces globisporus produced an enzyme which had lytic effects on streptococci and was able to solubilize their Fc-receptors. A new method for rapid purification of this enzyme was described. It consisted of adsorption to Amberlite CG 50 and subsequent chromatography on CM-cellulose Whatman CM 52. The purified en...

journal_title：Medical microbiology and immunology

authors： Tille D,Chhatwal GS,Blobel H

更新日期：1986-01-01 00:00:00

abstract：:Several lines of evidence suggest a viral infection as the initiating event for the development of myocarditis (MC). Especially enteroviruses like coxsackie B3 virus have been shown to induce MC in humans and strains of MC-prone mice after an infection. The further course of the disease is, however, determined not onl...

journal_title：Medical microbiology and immunology

authors： Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

更新日期：2004-05-01 00:00:00

abstract：:BALB/c male mice infected with the H3 variant of coxsackievirus B3 (CVB3) develop fulminant myocarditis. Age-matched female mice show little myocarditis due to decreased virus receptor expression on cardiac cells. TNFalpha and IL-1beta levels were increased in males by 3 days after infection. IFNgamma levels increased...

journal_title：Medical microbiology and immunology

authors： Huber SA

更新日期：2005-05-01 00:00:00

abstract：:Antibodies against the human coronavirus OC43 in human sera were measured by haemagglutination inhibition (HI), complement fixation (CF), and radial diffusion-haemolysis in gel (HIG) techniques. The apparent HI titres in a fraction of sera with no antibodies detectable by the two other methods were found to be reduced...

journal_title：Medical microbiology and immunology

authors： Hovi T

更新日期：1978-11-17 00:00:00