Variable degree of slime production is linked to different levels of beta-lactam susceptibility in Staphylococcus epidermidis phase variants.


:Recently we demonstrated that lack of mecA transcription was responsible for the decreased methicillin resistance phenotype of strongly slime-negative Staphylococcus epidermidis phase variants [Mempel M, Feucht H, Ziehbuhr W, Endres M, Laufs R, Grüter L (1994) Antimicrob Agents Chemother 38: 1251-1255]. In the present study we compared the beta-lactam susceptibility and the slime production capacity of 60 phenotypic variants of S. epidermidis parent strain RP62A identified by their colony morphology on congo red agar. We could show that the variable degree of slime production is linked to different levels of beta-lactam susceptibility in intermediate-stage phase variants. The increased deltahemolysin production of slime-negative phase variants may indicate an accessory gene regulator-like control.


Med Microbiol Immunol


Mempel M,Müller E,Hoffmann R,Feucht H,Laufs R,Grüter L




Has Abstract


1995-10-01 00:00:00












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    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章


    authors: Brade L,Schmidt WA

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  • Cloning of Clostridium difficile toxin B gene and demonstration of high N-terminal homology between toxin A and B.

    abstract::High titered Clostridium sordellii lethal toxin antiserum, cross-reactive with C. difficile cytotoxin B (ToxB), was used to isolate toxB fragments from a C. difficile expression library. Recombinant clones containing toxB fragments of the 5' and 3' end were isolate. A 2.5-kb HincII fragment of chromosomal DNA overlaps...

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  • Intrauterine therapy of cytomegalovirus infection with valganciclovir: review of the literature.

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    journal_title:Medical microbiology and immunology

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    journal_title:Medical microbiology and immunology

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    authors: Li H,Wang L,Ye L,Mao Y,Xie X,Xia C,Chen J,Lu Z,Song J

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    journal_title:Medical microbiology and immunology

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    authors: Yuhas Y,Nofech-Mozes Y,Weizman A,Ashkenazi S

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    journal_title:Medical microbiology and immunology

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  • Vaccination against infectious diseases: what is promising?

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    journal_title:Medical microbiology and immunology

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    更新日期:2014-12-01 00:00:00

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    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章


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    journal_title:Medical microbiology and immunology

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    journal_title:Medical microbiology and immunology

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    authors: Moser I,Hellmann E

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    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章


    authors: Mack D,Pulz M,Heesemann J

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  • Increased viability but decreased culturability of Mycobacterium avium subsp. paratuberculosis in macrophages from inflammatory bowel disease patients under Infliximab treatment.

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    authors: Nazareth N,Magro F,Appelberg R,Silva J,Gracio D,Coelho R,Cabral JM,Abreu C,Macedo G,Bull TJ,Sarmento A

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    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章


    authors: Willers H,Höpken W

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    authors: Nishio M,Tsurudome M,Ito M,Ito Y

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    journal_title:Medical microbiology and immunology

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    journal_title:Medical microbiology and immunology

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    authors: El-Huneidi W,Mui R,Zhang TH,Palmer M

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    journal_title:Medical microbiology and immunology

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    authors: Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

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    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审


    authors: Jacobson RL,Schlein Y,Eisenberger CL

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  • Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood.

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    journal_title:Medical microbiology and immunology

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    authors: Bache C,Spreitzer I,Becker B,Loeschner B,Rosskopf U,Hanschmann KM,Schwanig M,Schneider CK,Lieb B,Montag T

    更新日期:2012-08-01 00:00:00