Coxsackievirus B3 persistence and myocarditis in NFR nu/nu and +/nu mice.

abstract：:Virus adsorption and uptake of human rhinovirus 14 (HRV14) were studied with HeLa cells and baby hamster kidney (BHK) cells which were transfected with the HRV14 receptor intercellular adhesion molecule-1 (ICAM-1). Transmission electron microscopy of HeLa cells revealed that HRV14 was internalized via clathrin-coated ...

journal_title：Medical microbiology and immunology

authors： Grunert HP,Wolf KU,Langner KD,Sawitzky D,Habermehl KO,Zeichhardt H

更新日期：1997-06-01 00:00:00

abstract：:Several lines of evidence suggest a viral infection as the initiating event for the development of myocarditis (MC). Especially enteroviruses like coxsackie B3 virus have been shown to induce MC in humans and strains of MC-prone mice after an infection. The further course of the disease is, however, determined not onl...

journal_title：Medical microbiology and immunology

authors： Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

更新日期：2004-05-01 00:00:00

abstract：:Serum-starved human foreskin fibroblasts were infected by human cytomegalovirus (Towne strain) that is thought to induce DNA replication in host cells during lytic infection. At various times postinfection, the cultures were pulse labeled with either 3H-thymidine or 14C-thymidine and 3H-lysine to examine DNA synthesis...

journal_title：Medical microbiology and immunology

authors： Radsak K,Schmitz B

更新日期：1980-02-01 00:00:00

abstract：:Upon infection of human T-cell leukemia virus type I (HTLV-I)-carrying human T-cell lines such as MT-4, HTLV-III, a probable etiologic agent of acquired immune deficiency syndrome (AIDS) caused fast and strong cytopathic effects leading ultimately to the death of the cells. Such effects were preceded by the rapid indu...

journal_title：Medical microbiology and immunology

authors： Nakashima H,Koyanagi Y,Harada S,Yamamoto N

更新日期：1986-01-01 00:00:00

abstract：:BALB/c male mice infected with the H3 variant of coxsackievirus B3 (CVB3) develop fulminant myocarditis. Age-matched female mice show little myocarditis due to decreased virus receptor expression on cardiac cells. TNFalpha and IL-1beta levels were increased in males by 3 days after infection. IFNgamma levels increased...

journal_title：Medical microbiology and immunology

authors： Huber SA

更新日期：2005-05-01 00:00:00

abstract：:198 strains of Propionibacterium acnes, P. avidum, and P. granulosum were tested for their immunostimulatory potency using splenomegaly as index of stimulation, the activity differed widely from strain to strain. The antitumor and antimetastatic properties of six strains with differing stimulation activities were care...

journal_title：Medical microbiology and immunology

authors： Ko HL,Roszkowski W,Jeljaszewicz J,Pulverer G

更新日期：1981-01-01 00:00:00

abstract：:Streptomyces globisporus produced an enzyme which had lytic effects on streptococci and was able to solubilize their Fc-receptors. A new method for rapid purification of this enzyme was described. It consisted of adsorption to Amberlite CG 50 and subsequent chromatography on CM-cellulose Whatman CM 52. The purified en...

journal_title：Medical microbiology and immunology

authors： Tille D,Chhatwal GS,Blobel H

更新日期：1986-01-01 00:00:00

abstract：:The avirulent Salmonella typhimurium galE strain G30, following oral feeding to mice, developed a state of immunity to a secondary oral challenge with virulent Salmonella typhimurium. This immunity was concommitant with the development of intestinal and serum antibodies and delayed-type hyepersensitivity (DTH) to Salm...

journal_title：Medical microbiology and immunology

authors： Moser I,Hohmann A,Schmidt G,Rowley D

更新日期：1980-01-01 00:00:00

abstract：:A clinical trial was conducted with Alice/R-75 strain live attenuated intranasal influenza A/B vaccine. With double blind control 88 adult volunteers were administered 2 doses of Alice/R-75 vaccine, 93 volunteers received one dose of Alice/R-75 vaccine and one dose placebo solution and 94 subjects were administered 2 ...

journal_title：Medical microbiology and immunology

authors： Spencer MJ,Cherry JD,Powell KR,Sumaya CV

更新日期：1979-03-13 00:00:00

abstract：:The rapid and correct identification of pathogens is of paramount importance for the treatment of patients with invasive infections. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) can speed up the identification of bacteria and fungi and has quickly been embraced by medical...

journal_title：Medical microbiology and immunology

authors： Hamprecht A,Christ S,Oestreicher T,Plum G,Kempf VA,Göttig S

更新日期：2014-04-01 00:00:00

abstract：:Monoclonal antibody (MAb) 2c, specific for glycoprotein B of herpes simplex virus (HSV), had been shown to mediate clearance of infection from the mucous membranes of mice, thereby completely inhibiting mucocutaneous inflammation and lethality, even in mice depleted of both CD4(+) and CD8(+) cells. Additionally, gangl...

journal_title：Medical microbiology and immunology

authors： Däumer MP,Schneider B,Giesen DM,Aziz S,Kaiser R,Kupfer B,Schneweis KE,Schneider-Mergener J,Reineke U,Matz B,Eis-Hübinger AM

更新日期：2011-05-01 00:00:00

abstract：:In order to take the conditions of natural Herpes simplex virus (HSV) infection into consideration, the genetic resistance of C57-Bl mice, which was established by intraperitoneal HSV-1 infection [Lopez, 1975], was investigated in vaginally infected mice. The course of infection in the mucous membranes did not differ ...

journal_title：Medical microbiology and immunology

authors： Schneweis KE,Olbrich M,Saftig V,Scholz R

更新日期：1982-01-01 00:00:00

abstract：:Oral candidiasis (OC) is a frequent oral manifestation of HIV infection, is a marker disease and occurs as a pseudomembranous, erythematous or rarely hyperplastic variant; angular cheilitis is also seen. Candida albicans is frequently isolated but other species such as C. krusei and C. dublienensis are emerging. Resis...

journal_title：Medical microbiology and immunology

authors： Reichart PA

更新日期：2003-08-01 00:00:00

abstract：:It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetr...

journal_title：Medical microbiology and immunology

authors： Jankovičová J,Neuerová Z,Sečová P,Bartóková M,Bubeníčková F,Komrsková K,Postlerová P,Antalíková J

更新日期：2020-08-01 00:00:00

abstract：:A set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of inc...

journal_title：Medical microbiology and immunology

authors： Nord C-E,Linberg AA,Dahlbäck A

更新日期：1975-09-19 00:00:00

abstract：:We previously reported that Trypanosoma cruzi, the agent of Chagas disease, induces in congenitally infected fetuses a strong, adult-like parasite-specific CD8(+) T cell response producing IFN-γ (Hermann et al. in Blood 100:2153-2158, 2002). This suggests that the parasite is able to overcome the immaturity of neonata...

journal_title：Medical microbiology and immunology

authors： Rodriguez P,Carlier Y,Truyens C

更新日期：2012-05-01 00:00:00

abstract：:The DNAs of two kinds of microorganisms from human leprosy lesion, Mycobacterium leprae and Corynebacterium tuberculostearicum (also known as "leprosy-derived corynebacterium" or LDC), have been analysed and compared with the genomes of reference bacteria of the CMN group (genera Corynebacterium, Mycobacterium and Noc...

journal_title：Medical microbiology and immunology

authors： Hottat F,Coene M,Cocito C

更新日期：1988-01-01 00:00:00

abstract：:The yeast Candida albicans is part of the microflora in most healthy people, but can become a pathogen when host defenses are compromised. The phenotypic plasticity of C. albicans, which includes switching between different morphologies, contributes to its ability to colonize and infect virtually all body locations. A...

journal_title：Medical microbiology and immunology

authors： Morschhäuser J

更新日期：2010-08-01 00:00:00

abstract：:Phosphorylcholine (ChoP) is covalently incorporated into bacterial surface structures, contributing to host mimicry and promoting adhesion to surfaces. Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which surface structures bear ChoP, and whethe...

journal_title：Medical microbiology and immunology

authors： Ihalin R,Zhong D,Karched M,Chen C,Asikainen S

更新日期：2018-11-01 00:00:00

abstract：:Adaptation of Borrelia burgdorferi in the vector and vertebrate host is mediated by mechanisms that regulate differential expression of outer surface lipoproteins (Osps). In this study, real time PCR was applied to quantify tissue-specific expression of four linear plasmid (lp54)-encoded (ospA, zs7.a36, zs7.a66 zs7.a6...

journal_title：Medical microbiology and immunology

authors： Lederer S,Brenner C,Stehle T,Gern L,Wallich R,Simon MM

更新日期：2005-01-01 00:00:00

abstract：:Both aging and treated human immunodeficiency virus (HIV) infection are characterized by low-level chronic inflammation and immune activation which contribute to the development of age-related diseases, frailty, and early mortality. Chronic cytomegalovirus (CMV) infection is highly prevalent in older adults and HIV-in...

journal_title：Medical microbiology and immunology

authors： Tavenier J,Margolick JB,Leng SX

更新日期：2019-08-01 00:00:00

abstract：:In resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen for early infections. We evaluated the performance of the antibody and antigen components of the...

journal_title：Medical microbiology and immunology

authors： Wratil PR,Rabenau HF,Eberle J,Stern M,Münchhoff M,Friedrichs I,Stürmer M,Berger A,Kuttner-May S,Münstermann D,Lucht A,Meixenberger K,Bannert N,Keppler OT

更新日期：2020-04-01 00:00:00

abstract：:Pertussis Toxin (PTx) is one of the most important virulence factors of Bordetella pertussis, the cause of whooping cough. Therefore, the inactivated toxin is an obligatory constituent of acellular pertussis vaccines. It is described in the literature that both native PTx and recombinant Pertussis Toxin (PTg) activate...

journal_title：Medical microbiology and immunology

authors： Bache C,Spreitzer I,Becker B,Loeschner B,Rosskopf U,Hanschmann KM,Schwanig M,Schneider CK,Lieb B,Montag T

更新日期：2012-08-01 00:00:00

abstract：:Almost 4000 sera from seven African states were examined for antibodies to ATLV/HTLV-1. Between 1% and 8% of healthy people from sub-Saharan Africa have such antibodies. The highest frequency was observed in Gabon. There were considerable variations between villages. The percentage of seropositives and the mean titre ...

journal_title：Medical microbiology and immunology

authors： Hunsmann G,Bayer H,Schneider J,Schmitz H,Kern P,Dietrich M,Büttner DW,Goudeau AM,Kulkarni G,Fleming AF

更新日期：1984-01-01 00:00:00

abstract：:Proteus mirabilis (P. mirabilis), a gram-negative enteric bacterium, frequently causes urinary tract infections. Many virulence factors of uropathogenic P. mirabilis have been identified, including urease, flagella, hemolysin and fimbriae. However, the functions of polyphosphate kinase (PPK), which are related to the ...

journal_title：Medical microbiology and immunology

authors： Peng L,Jiang Q,Pan JY,Deng C,Yu JY,Wu XM,Huang SH,Deng XY

更新日期：2016-04-01 00:00:00

abstract：:Interactions of virulent Leptospira interrogans with murine monocyte-macrophage-like J774A.1 cells and Vero (African green monkey kidney fibroblasts) cells from attachment to internalization were investigated by a series of morphological analysis. Fontana silver staining revealed that only the pathogenic leptospires w...

journal_title：Medical microbiology and immunology

authors： Liu Y,Zheng W,Li L,Mao Y,Yan J

更新日期：2007-12-01 00:00:00

abstract：:Two antigens were isolated from the culture filtrates of H37Ra Mycobacterium tuberculosis by immunoabsorbent affinity chromatography, M. tuberculosis antigen 5 and immunoabsorbent affinity column-purified antigen (IAP). The potential application of these two mycobacterial antigens in the laboratory diagnosis of tuberc...

journal_title：Medical microbiology and immunology

authors： Krishnan VV,Mathai A

更新日期：1991-01-01 00:00:00

abstract：:The effects of sheep anti-murine recombinant tumor necrosis factor-alpha (TNF-alpha) on resistance to Listeria monocytogenes infection were studied in T cell-deficient nu/nu mice. The sheep anti-TNF-alpha antibody preparation was specific for TNF since it neutralized 300 U of recombinant murine TNF-alpha in vitro at a...

journal_title：Medical microbiology and immunology

authors： Hauser T,Frei K,Zinkernagel RM,Leist TP

更新日期：1990-01-01 00:00:00

abstract：:The streptococcal pyrogenic exotoxin B (SpeB) is known to be involved in group A streptococcus (GAS) survival in blood, but the detailed mechanism is not clear. For clarification of this issue, speB isogenic mutants of strains M6 and M49 were constructed by using an integrational plasmid and confirmed by Southern blot...

journal_title：Medical microbiology and immunology

authors： Chiang-Ni C,Wang CH,Tsai PJ,Chuang WJ,Lin YS,Lin MT,Liu CC,Wu JJ

更新日期：2006-06-01 00:00:00

abstract：:Cytomegaloviruses (CMVs) are large double-stranded DNA viruses that replicate slowly and cause life-long persisting infections in their hosts. To achieve this, the CMVs had to evolve numerous countermeasures against innate and adaptive immune responses. Induction of programmed cell death is one important host defense ...

journal_title：Medical microbiology and immunology

authors： Handke W,Krause E,Brune W

更新日期：2012-11-01 00:00:00