0 antigen distribution and sensitivity to the bactericidal effect of normal human serum of Proteus strains from clinical specimens.

Abstract:

:9 antigen distribution and sensitivity to the bactericidal effect of normal human serum were determined in 485 Proteus strains isolated from urine, blood, wounds, and feces. Of all strains, 62% could be grouped according to 25 0 antigens. The most frequent one, 0 3, appeared in 13% of all the strains. In blood cultures this antigen was found significantly more often. No other 0 group dominated. Of all strains, 11% were spontaneously agglutinating but such strains were significantly more common in urinary specimens from children with neurogenic bladder disorders. Strains sensitive to the bactericidal effect of normal human serum were significantly more prevalent in urines than in fecal specimens. Most of the sensitive strains were spontaneously agglutinating and were isolated from the urines of children with neurogenic bladder disorders. This may be an example of 'antigenic drift' of the bacteria as a response to host defense mechanisms in the urinary tract.

journal_name

Med Microbiol Immunol

authors

Larsson P,Olling S

doi

10.1007/BF02121822

subject

Has Abstract

pub_date

1977-07-18 00:00:00

pages

77-82

issue

2

eissn

0300-8584

issn

1432-1831

journal_volume

163

pub_type

杂志文章
  • Generation, characterization and cross-reactivities of monoclonal antibodies against the p24 core protein and the gp130 envelope glycoprotein of HIV-2ben.

    abstract::The purpose of this study was to characterize antigenic determinants on structural polypeptides of human immunodeficiency virus type 2 (HIV-2ben). Therefore, three HIV-2-specific monoclonal antibodies (mAbs) against the p24 core protein (gag) and one mAb against the gp130 envelope glycoprotein (env) were produced. In ...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00190264

    authors: Faisst AC,Otteken A,Nick S,Hunsmann G

    更新日期:1993-07-01 00:00:00

  • Clinical evaluation of prophylactic intranasal 1-phenyl-3-(4-phenyl-2-thiazolyl) guanidine (CL 88,277) medication against rhinovirus 44 challenge.

    abstract::The prophylactic intranasal medication with a new antiviral compound, 1-phenyl-3-(4 phenyl-2-thiazolyl) guanidine (CL 88,277) was evaluated in humans against rhinovirus 44 challenge. One ml containing 250 mg of CL 88,277 was administered to 10 seronegative volunteers three times a day plus one dose prior to the rhinov...

    journal_title:Medical microbiology and immunology

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02126707

    authors: Togo Y,Durr FE,Laurenzana DA

    更新日期:1977-05-18 00:00:00

  • Immunogenicity of some common thermolabile surface antigens of Escherichia coli.

    abstract::The development in rabbits of antibodies against common thermolabile Escherichia coli surface antigens - and against O and K antigens - was investigated. Three strains, E3b (O75:K95:H5), E56b (O8:K27:H-), and H61 (O45:K1:H10), and five rabbits per strain were used. Immunization was carried out by routine procedures us...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02122676

    authors: Orskov F,Larsen JC,Orskov I

    更新日期:1981-01-01 00:00:00

  • Clonal differentiation of uropathogenic Escherichia coli isolates of serotype O6:K5 by fimbrial antigen typing and DNA long-range mapping techniques.

    abstract::Escherichia coli isolates of serotype O6:K5 are the most common causative agents of cystitis and pyelonephritis in adults. To answer the question, as to whether strains of this particular serotype represent one special clonal group, out of a collection of 34 serotype O6:K5 isolates [Zingler et al. (1990) Zentralbl. Ba...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00195947

    authors: Zingler G,Blum G,Falkenhagen U,Orskov I,Orskov F,Hacker J,Ott M

    更新日期:1993-03-01 00:00:00

  • Interferon induces an antiviral state in ganglioside-deficient transformed mouse fibroblasts.

    abstract::The antiviral activity of mouse fibroblast interferon against vesicular stomatitis virus was investigated in L-929 mouse fibroblasts and the ganglioside-deficient L-929 mutant cells (ATCC clone NCTC 2071). Although it has been widely reported that gangliosides serve as primary receptors for interferon at the cellular ...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02125527

    authors: Schiffmann D,Koschel K

    更新日期:1981-01-01 00:00:00

  • Differences and overlaps between Phd studies in diagnostic microbiology in industrial and academic settings.

    abstract::Industrial and academic needs for innovation and fundamental research are essential and not widely different. Depending on the industrial setting, research and development (R&D) activities may be more focused on the developmental aspects given the need to ultimately sell useful products. However, one of the biggest di...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1007/s00430-019-00643-4

    authors: van Belkum A,Pelegrin AC,Datar R,Goyal M,Palmieri M,Mirande C,Chalansonnet V,Orenga S

    更新日期:2020-06-01 00:00:00

  • Avoiding artifacts in the infant rat model for bacterial meningitis: use of Sangur test strips for the rapid quantification of blood contamination in cerebrospinal fluid.

    abstract::The infant rat model is widely used to study the pathogenesis of meningitis caused by a variety of gram-positive and gram-negative bacteria. However, the interpretation of published results concerning meningitis is difficult in many records because the fact that blood contamination of the cerebrospinal fluid (CSF) can...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s004300050011

    authors: Vogel U,Steinmetz I,Frosch M

    更新日期:1996-05-01 00:00:00

  • Simultaneous analysis of multiple T helper subsets in leprosy reveals distinct patterns of Th1, Th2, Th17 and Tregs markers expression in clinical forms and reactional events.

    abstract::Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper (Th) and regulatory T cells (Tregs). Then, aiming at clarifying the immune response, ...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-017-0519-9

    authors: Azevedo MCS,Marques H,Binelli LS,Malange MSV,Devides AC,Silva EA,Fachin LRV,Ghidella CC,Soares CT,Garlet GP,Rosa PS,Belone AFF,Trombone APF

    更新日期:2017-12-01 00:00:00

  • Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain.

    abstract::We assessed whether the intracellular bacterium Chlamydia pneumoniae was present in post-mortem brain samples from patients with and without late-onset Alzheimer's disease (AD), since some indirect evidence seems to suggest that infection with the organism might be associated with the disease. Nucleic acids prepared f...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s004300050071

    authors: Balin BJ,Gérard HC,Arking EJ,Appelt DM,Branigan PJ,Abrams JT,Whittum-Hudson JA,Hudson AP

    更新日期:1998-06-01 00:00:00

  • The clinical value of neutrophil extracellular traps.

    abstract::Neutrophil extracellular traps (NETs) have recently been discovered as a central part of antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also generated upon non-infectious stimuli in various clinical settings. In acute or chronic inflammatory disorders aberrantly enhanced NET format...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1007/s00430-009-0121-x

    authors: Lögters T,Margraf S,Altrichter J,Cinatl J,Mitzner S,Windolf J,Scholz M

    更新日期:2009-11-01 00:00:00

  • Hepatitis A virus in cell culture. II. Growth characteristics of hepatitis A virus in Frhk-4/R cells.

    abstract::The propagation of hepatitis A virus (HAV) is shown in a rapidly growing fetal rhesus monkey kidney cell line (Frhk-4/R). In the course of ten passages through Frhk-4/R cells the HAV, which was released in the supernatants of the cell cultures, was adapted to these cells. In the tenth passage 6 days after infection, i...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02122671

    authors: Flehmig B

    更新日期:1981-01-01 00:00:00

  • In vitro binding of Campylobacter jejuni surface proteins to murine small intestinal cell membranes.

    abstract::Surface proteins of nine Campylobacter jejuni strains belonging to three different serovia were extracted with lysozyme/ethylenediamine-tetraacetic acid. The preparations bound to isolated murine small intestinal cells and to a membrane fraction (MF) of isolated brush borders obtained by detergent treatment with Trito...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00202555

    authors: Moser I,Hellmann E

    更新日期:1989-01-01 00:00:00

  • Antibacterial effect of bovine milk antibody against Escherichia coli in a mouse indigenous infection model.

    abstract::A skim-milk fraction and a whey-protein concentrate (WPC) fraction were prepared from the cows that had been immunized with E. coli isolated from the mouse intestine. The antibacterial effect of these fractions against E. coli was examined. They contained antibody with a high affinity for E. coli strain 48, a represen...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00189427

    authors: Nomoto K,Matsuoka Y,Hayakawa K,Ohwaki M,Kan T,Yoshikai Y,Nomoto K

    更新日期:1992-01-01 00:00:00

  • Isolation of two antigens from the culture filtrates of Mycobacterium tuberculosis and their applications in the laboratory diagnosis of the tuberculous meningitis.

    abstract::Two antigens were isolated from the culture filtrates of H37Ra Mycobacterium tuberculosis by immunoabsorbent affinity chromatography, M. tuberculosis antigen 5 and immunoabsorbent affinity column-purified antigen (IAP). The potential application of these two mycobacterial antigens in the laboratory diagnosis of tuberc...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00193851

    authors: Krishnan VV,Mathai A

    更新日期:1991-01-01 00:00:00

  • Interaction between Clostridium difficile and polymorphonuclear leucocytes from the elderly and post-operative cancer patients: phagocytosis and bactericidal function.

    abstract::The ability of polymorphonuclear leucocytes (PMNs) from elderly healthy subjects and post-operative cancer patients to ingest and kill Clostridium difficile was studied. The percentage of phagocytosis in clinically healthy subjects aged 69-82 years ranged from 20.2 +/- 3.2 (mean +/- SD) to 34.1 +/- 4.2, depending on t...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02123569

    authors: Bassaris HP,Lianou PE,Legakis NJ,Papavassiliou JT

    更新日期:1984-01-01 00:00:00

  • Human cytomegalovirus riding the cell cycle.

    abstract::Human cytomegalovirus (HCMV) infection modulates the host cell cycle to create an environment that is optimal for viral gene expression, DNA replication, and production of infectious virus. The virus mostly infects quiescent cells and thus must push the cell into G1 phase of the cell cycle to co-opt the cellular mecha...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1007/s00430-015-0396-z

    authors: Spector DH

    更新日期:2015-06-01 00:00:00

  • Human papilloma virus (HPV) infection leads to the development of head and neck lesions but offers better prognosis in malignant Indian patients.

    abstract::Head and neck cancers constitute a multifactorial global disease burden and are associated with human papilloma virus (HPV) as a possible risk factor. The aim of the study is to understand the relationship between HPV and the development of head and neck lesions in Indian patients. To this end, frequency of HPV was as...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-017-0502-5

    authors: Sarkar S,Alam N,Chakraborty J,Biswas J,Mandal SS,Roychoudhury S,Panda CK

    更新日期:2017-06-01 00:00:00

  • Highly individual patterns of virus-immune IgG effector responses in humans.

    abstract::IgG responses are fundamental to adaptive immunity and document immunological memory of previous pathogen encounter. While specific antigen recognition is mediated by the variable F(ab')2 domain of IgG, various effector functions become activated via the constant Fcγ part bridging IgG-opsonized targets to FcγR-express...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-016-0457-y

    authors: Corrales-Aguilar E,Trilling M,Reinhard H,Falcone V,Zimmermann A,Adams O,Santibanez S,Hengel H

    更新日期:2016-10-01 00:00:00

  • Influence of the age of sheep red blood cells on virus-induced and hypotonic hemolysis.

    abstract::The effect of red blood cell age on the susceptibility towards NDV- induced hemolysis has been investigated. It was found that young sheep red blood cells (SRBC), although more resistant to hypotonic hemolysis, are more susceptible towards viral hemolysis than older cells. This may be because young red blood cells hav...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02122855

    authors: Sziegoleit A,Füssle R,Wellensiek HJ

    更新日期:1980-01-01 00:00:00

  • An immunodominant 30-kDa antigen of a candidate anti-leprosy vaccine, Mycobacterium w, shares T and B cell determinants with M. leprae and M. tuberculosis.

    abstract::Earlier we reported that vaccination of leprosy patients with Mycobacterium w induces an immune response directed predominantly against low molecular weight antigens. One of these antigens, with a molecular mass of 30-kDa, was recognized by a majority of the vaccinated subjects as well as the tuberculoid leprosy patie...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF00579623

    authors: Yadava A,Mukherjee R

    更新日期:1993-11-01 00:00:00

  • Transcripts expressed in cytomegalovirus latency coding for an antigenic IE/E phase peptide that drives "memory inflation".

    abstract::Roizman's definition of herpesviral latency, which applies also to cytomegaloviruses (CMVs), demands maintenance of reactivation-competent viral genomes after clearance of productive infection. It is more recent understanding that failure to complete the productive viral cycle for virus assembly and release does not i...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-019-00615-8

    authors: Renzaho A,Schmiedeke JK,Griessl M,Kühnapfel B,Seckert CK,Lemmermann NAW

    更新日期:2019-08-01 00:00:00

  • Quantitative analysis of Borrelia burgdorferi gene expression in naturally (tick) infected mouse strains.

    abstract::Adaptation of Borrelia burgdorferi in the vector and vertebrate host is mediated by mechanisms that regulate differential expression of outer surface lipoproteins (Osps). In this study, real time PCR was applied to quantify tissue-specific expression of four linear plasmid (lp54)-encoded (ospA, zs7.a36, zs7.a66 zs7.a6...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-004-0218-1

    authors: Lederer S,Brenner C,Stehle T,Gern L,Wallich R,Simon MM

    更新日期:2005-01-01 00:00:00

  • Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood.

    abstract::Pertussis Toxin (PTx) is one of the most important virulence factors of Bordetella pertussis, the cause of whooping cough. Therefore, the inactivated toxin is an obligatory constituent of acellular pertussis vaccines. It is described in the literature that both native PTx and recombinant Pertussis Toxin (PTg) activate...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-012-0238-1

    authors: Bache C,Spreitzer I,Becker B,Loeschner B,Rosskopf U,Hanschmann KM,Schwanig M,Schneider CK,Lieb B,Montag T

    更新日期:2012-08-01 00:00:00

  • Live and let die: manipulation of host hepatocytes by exoerythrocytic Plasmodium parasites.

    abstract::The generation of rodent Plasmodium strains expressing fluorescent proteins in all life cycle stages has had a big impact on malaria research. With this tool in hand, for the first time it was possible to follow in real time by in vivo microscopy the infection route of Plasmodium sporozoites transmitted to the mammali...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1007/s00430-007-0044-3

    authors: Sturm A,Heussler V

    更新日期:2007-09-01 00:00:00

  • Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.

    abstract::In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4-6 weeks, followed by ivermectin (IVM) after 6 months. After 6-27 months, efficacy was evaluated by onchocercoma histology, PCR and microfilariae determination. Administration of doxycycline resulted in ...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00430-007-0062-1

    authors: Hoerauf A,Specht S,Büttner M,Pfarr K,Mand S,Fimmers R,Marfo-Debrekyei Y,Konadu P,Debrah AY,Bandi C,Brattig N,Albers A,Larbi J,Batsa L,Taylor MJ,Adjei O,Büttner DW

    更新日期:2008-09-01 00:00:00

  • Modulation of the lung local immune response by systemic immunization.

    abstract::The present study describes the respiratory immune response of mice to locally administered antigen, and the modulation of this response by systemic immunization. Intranasal immunization of mice with the A/PR/8/34 strain of influenza virus evoked local antibody response of the IgA type. The titer of the IgA antibodies...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/BF02121133

    authors: Zakay-Rones Z,Hadas O,Levy R

    更新日期:1978-11-17 00:00:00

  • Pathogenesis of leptospirosis: interaction of Leptospira interrogans with in vitro cultured mammalian cells.

    abstract::Interactions of virulent Leptospira interrogans with murine monocyte-macrophage-like J774A.1 cells and Vero (African green monkey kidney fibroblasts) cells from attachment to internalization were investigated by a series of morphological analysis. Fontana silver staining revealed that only the pathogenic leptospires w...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-007-0047-0

    authors: Liu Y,Zheng W,Li L,Mao Y,Yan J

    更新日期:2007-12-01 00:00:00

  • Increased viability but decreased culturability of Mycobacterium avium subsp. paratuberculosis in macrophages from inflammatory bowel disease patients under Infliximab treatment.

    abstract::Mycobacterium avium subsp. paratuberculosis (MAP) has long been implicated as a triggering agent in Crohn's disease (CD). In this study, we investigated the growth/persistence of both M. avium subsp. hominissuis (MAH) and MAP, in macrophages from healthy controls (HC), CD and ulcerative colitis patients. For viability...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-015-0393-2

    authors: Nazareth N,Magro F,Appelberg R,Silva J,Gracio D,Coelho R,Cabral JM,Abreu C,Macedo G,Bull TJ,Sarmento A

    更新日期:2015-12-01 00:00:00

  • Clinical utility of measuring Epstein-Barr virus-specific cell-mediated immunity after HSCT in addition to virological monitoring: results from a prospective study.

    abstract::Lack of virus-specific cell-mediated immunity (CMI) is associated with worse viral infection outcome in hematopoietic stem cell transplantation (HSCT). We aimed to evaluate the role of immunological monitoring of Epstein-Barr virus (EBV) infection in addition to virological one in 33 adult and 18 pediatric allogeneic ...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章

    doi:10.1007/s00430-019-00629-2

    authors: Chiereghin A,Piccirilli G,Belotti T,Prete A,Bertuzzi C,Gibertoni D,Gabrielli L,Turello G,Borgatti EC,Barbato F,Sessa M,Arpinati M,Bonifazi F,Lazzarotto T

    更新日期:2019-12-01 00:00:00

  • Herpes simplex and varicella-zoster virus infections during pregnancy: current concepts of prevention, diagnosis and therapy. Part 2: Varicella-zoster virus infections.

    abstract::Varicella during pregnancy can be associated with severe illnesses for both the mother and her neonate. Varicella pneumonia must be regarded as a medical emergency, since pregnant women are at risk of life-threatening ventilatory compromise and death. After maternal chickenpox in the first and second trimesters, conge...

    journal_title:Medical microbiology and immunology

    pub_type: 杂志文章,评审

    doi:10.1007/s00430-006-0032-z

    authors: Sauerbrei A,Wutzler P

    更新日期:2007-06-01 00:00:00